[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"extreme-longevity\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:extreme-longevity":25},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,2,0,[8,40],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":4,"eligibilityCriteria":15,"healthyVolunteers":16,"sex":17,"minAge":18,"maxAge":4,"enrollmentInfo":19,"targetDuration":4,"studyType":22,"phases":4,"briefSummary":23,"conditions":24,"keywords":26,"overallStatus":28,"whyStopped":4,"lastUpdateSubmitDate":29,"lastUpdatePostDateStruct":30,"startDateStruct":33,"completionDateStruct":35,"leadSponsor":37,"locationsCount":5},"100110848","the-longevity-genes-in-founder-populations-project-100110848",false,"NCT00707694","The Longevity Genes in Founder Populations Project","Searching for Longevity Genes in the Historically Unique Ashkenazi Jewish Population","Inclusion Criteria:\n\n* Ashkenazi Jewish, age 95+,\n* Offspring of person age 95+,\n* Offspring of parents who died age 70 or younger.\n\nExclusion Criteria:\n\n* Non-Ashkenazis",true,"ALL","65 Years",{"count":20,"type":21},2000,"ESTIMATED","OBSERVATIONAL","We believe extreme longevity is due to specific genes which function to delay aging and prevent disease. The purpose of the research is to identify the genes\u002Fmutations associated with healthier aging; to understand the biological functions of these genes\u002Fmutations; and to develop therapies to replicate these preservative genetic activities in individuals who do not have the genetic profile for longevity.",[25],"Extreme Longevity",[27],"95 years of age and older","RECRUITING","2025-12-30",{"date":31,"type":32},"2026-01-02","ACTUAL",{"date":34,"type":32},"1998-07",{"date":36,"type":21},"2032-12",{"name":38,"class":39},"Albert Einstein College of Medicine","OTHER",{"id":41,"slug":42,"hasResults":11,"nctId":43,"briefTitle":44,"officialTitle":44,"acronym":45,"eligibilityCriteria":46,"healthyVolunteers":16,"sex":17,"minAge":47,"maxAge":4,"enrollmentInfo":48,"targetDuration":4,"studyType":22,"phases":4,"briefSummary":50,"conditions":51,"keywords":4,"overallStatus":28,"whyStopped":4,"lastUpdateSubmitDate":55,"lastUpdatePostDateStruct":56,"startDateStruct":58,"completionDateStruct":60,"leadSponsor":62,"locationsCount":64},"100544836","longevity-families-of-the-netherlands-100544836","NCT06374069","Longevity Families of the Netherlands","LOF-NL","Inclusion Criteria:\n\n* Siblings of Dutch Caucasian descent age 75+ enriched for familial longevity\n* Individuals of Dutch Caucasian descent age 75+ who are not enriched for familial longevity\n\nExclusion Criteria:\n\n\\-","75 Years",{"count":49,"type":21},600,"The demographic life expectancy enhancement of the past 150 years imposes an urgent challenge in Western and economically growing societies to stimulate the healthy lifespan that is lagging behind. Families surviving into exceptionally high ages (longevity) in good physical and mental health illustrate that this is physiologically possible. Such families harbor cross generational socio-genetic mechanisms that mediate healthy aging and protection from (multi)morbidity.\n\nThe purpose of our research is: to identify gene variants associated with healthy aging and protection from (multi)morbidity; to study the social-, environment- and behavioral factors of familial longevity, their role in (multi-)morbidity and its interaction with the genetic component.",[52,53,25,54],"Longevity","Familial Longevity","Aging","2024-04-15",{"date":57,"type":32},"2024-04-18",{"date":59,"type":32},"2023-09-11",{"date":61,"type":21},"2026-12",{"name":63,"class":39},"Leiden University Medical Center",1]