[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"extremity-injury\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:extremity-injury":29},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,3,0,[8,53,86],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":4,"eligibilityCriteria":15,"healthyVolunteers":11,"sex":16,"minAge":17,"maxAge":18,"enrollmentInfo":19,"targetDuration":4,"studyType":22,"phases":23,"briefSummary":25,"conditions":26,"keywords":34,"overallStatus":40,"whyStopped":4,"lastUpdateSubmitDate":41,"lastUpdatePostDateStruct":42,"startDateStruct":45,"completionDateStruct":47,"leadSponsor":49,"locationsCount":52},"100586924","pilot-trial-for-woundx-clinical-decision-support-tool-100586924",false,"NCT06921707","Pilot Trial for WounDx™ Clinical Decision Support Tool","SC2i-WounDx-001-WounDx™ Pilot Trial: Proof of Concept Feasibility for the Clinical Operations of WounDx™ in Aiding Clinicians Identify Wounds That Are Ready For Surgical Closure","Inclusion Criteria:\n\n* Wound surface area ≥75cm 2\n* Extremity injury (including shoulder and buttock - without visceral communication)\n* Wound amenable to Negative Pressure Wound Therapy using 3M™ V.A.C. ® canisters without gel pack\n\nExclusion Criteria:\n\n* Insulin Dependent Diabetes\n* Peripheral Vascular Disease\n* Connective Tissue Disorders\n* Preexisting immunosuppressive conditions or immunosuppression therapy\n* Pregnancy\n* Prisoners","ALL","18 Years","65 Years",{"count":20,"type":21},40,"ESTIMATED","INTERVENTIONAL",[24],"NA","The purpose of this research is to evaluate the overall use of the WounDx medical device in a clinical setting, such as a hospital. The WounDx device is experimental and not yet approved by the United States Food and Drug Administration (FDA). WounDx uses information about a patient's wound to generate a report that a surgeon may use to help determine when to close or not close the wound. The final decision to close the wound remains with the surgeon. The results from this pilot trial will inform a larger pivotal trial.",[27,28,29,30,31,32,33],"Wounds","Wounds and Injuries","Extremity Injury","Traumatic Wounds and Injuries","Amputation, Traumatic\u002FSurgery","Amputation, Wound","Open Fracture Wounds",[27,29,35,36,37,38,39],"Clinical Decision Support Tool","Delayed Wound Closure","Cytokine Biomarkers","Wound Effluent","Traumatic Extremity Wounds","RECRUITING","2026-04-14",{"date":43,"type":44},"2026-04-17","ACTUAL",{"date":46,"type":21},"2026-03-21",{"date":48,"type":21},"2026-09-20",{"name":50,"class":51},"Henry M. Jackson Foundation for the Advancement of Military Medicine","OTHER",5,{"id":54,"slug":55,"hasResults":11,"nctId":56,"briefTitle":57,"officialTitle":57,"acronym":58,"eligibilityCriteria":59,"healthyVolunteers":11,"sex":16,"minAge":17,"maxAge":4,"enrollmentInfo":60,"targetDuration":4,"studyType":62,"phases":4,"briefSummary":63,"conditions":64,"keywords":74,"overallStatus":40,"whyStopped":4,"lastUpdateSubmitDate":77,"lastUpdatePostDateStruct":78,"startDateStruct":80,"completionDateStruct":82,"leadSponsor":84,"locationsCount":5},"100617117","procedural-sedation-and-analgesia-for-treatment-of-adults-with-fractures-and-dislocations-in-the-emergency-department-100617117","NCT07314450","Procedural Sedation and Analgesia for Treatment of Adults With Fractures and Dislocations in the Emergency Department","PAINEX","Inclusion Criteria:\n\n1. Age ≥18.\n2. Patients with the following injuries are eligible:\n\n   1. Reduction treatment of shoulder dislocation\n   2. Reduction treatment of elbow dislocation\n   3. Reduction treatment of distal radius fractures, application of cast\n   4. Reduction treatment of finger fractures\u002Fdislocation\n   5. Casting treatment of upper extremity fractures\n\n      * Proximal humerus fracture, application of fixed sling\n      * Humeral shaft fracture, application of Sarmiento brace\n      * Supracondylar fracture, application of angled cast\n   6. Reduction treatment of hip dislocation\n   7. Reduction treatment of patella dislocation\n   8. Reduction of tibial shaft fracture, application of cast\n   9. Reduction treatment of ankle fractures including distal tibia fracture\n   10. Reduction treatment for toe fractures\u002Fdislocation\n   11. Casting treatment of lower extremity fractures\n\n       * Distal femur fracture, application of cast\u002Ftraction\n       * Proximal tibia fracture, application of cast or hinged brace\n       * Ankle fracture, application of walker\n\nExclusion Criteria:\n\n1. Unable to give informed consent (e.g. unconscious, psychotic or dementia)\n2. Unwilling to participate in the study\n3. Prior inclusion in the study\n4. Already included in another clinical study at the same day\u002Fhospital visit\n5. Pregnant or breastfeeding",{"count":61,"type":21},200,"OBSERVATIONAL","The goal of this observational study is to evaluate the effectiveness and safety of different procedural sedation and analgesia methods used for adults with painful fractures requiring reduction treatment in the emergency department.\n\nThe main questions it aims to answer are:\n\n* Which sedation and analgesia methods provide the best patient satisfaction and pain relief?\n* How do different treatment methods affect clinician satisfaction and the occurrence of adverse events?\n\nThe investigators will compare different types of procedural sedative and analgesic treatments (such as systemic sedation\u002Fanalgesia and regional techniques like nerve or hematoma blocks) to see which approach offers the best patient satisfaction and most effective pain control.\n\nParticipants will:\n\nBe adult patients with upper or lower extremity fractures or joint dislocations requiring painful reduction procedures.\n\nReceive one of the routinely used sedation or analgesia treatments (or no analgesia) during their emergency department care.\n\nReport their pain levels and satisfaction before, during, and after treatment. Be monitored for any side effects, complications, or use of antidotes. Data will be collected over a six-month period at Odense University Hospital, Holbæk Hospital, and Zealand University Hospital, Køge, following the STROBE guidelines for observational studies.",[65,66,29,67,68,69,70,71,72,73],"Pain, Procedural","Analgesia","Patient Satisfaction","Satisfaction, Personal","Satisfaction","Upper Extremity Injury","Lower Extremity Fracture","Upper Extremity Fracture","Extremity Injuries Lower",[75,76],"Emergency Department","Procedural sedation and analgesia","2025-12-17",{"date":79,"type":44},"2026-01-02",{"date":81,"type":44},"2025-07-29",{"date":83,"type":21},"2026-07-01",{"name":85,"class":51},"Region Zealand",{"id":87,"slug":88,"hasResults":11,"nctId":89,"briefTitle":90,"officialTitle":91,"acronym":4,"eligibilityCriteria":92,"healthyVolunteers":11,"sex":16,"minAge":17,"maxAge":93,"enrollmentInfo":94,"targetDuration":4,"studyType":62,"phases":4,"briefSummary":96,"conditions":97,"keywords":100,"overallStatus":109,"whyStopped":4,"lastUpdateSubmitDate":110,"lastUpdatePostDateStruct":111,"startDateStruct":113,"completionDateStruct":115,"leadSponsor":117,"locationsCount":4},"100541205","inoss-mbcp-putty-ortho-100541205","NCT06326827","In'Oss™ (MBCP® Putty) Ortho","Study of the Osteoconductive Potential of the Injectable Bone Substitute In'Oss™ (MBCP® Putty) in the Filling of Orthopaedic Bone Defects","Inclusion Criteria:\n\n1. Patient is male or female, 18 - 85 years old;\n2. Patient is willing and able to give written informed consent;\n3. Patient is able to comply with a prior medical examination;\n4. Patient is or has been scheduled for a surgical procedure to correct epiphyso-metaphyseal and\u002For metaphyso-diaphyseal bone defect in one of the following anatomical locations:\n\n   * Proximal humerus ▪ Distal radius\n   * Distal femur ▪ Proximal tibia ▪ Distal tibia\n5. Patient is willing and able to comply with the study procedures during surgery and the post-surgical follow up period, up to 12 months.\n\nExclusion Criteria:\n\n1. Patient has had an infection in the same extremity within last 24 months;\n2. Patient has signs of necrosis at the surgical site;\n3. Patient has cellulitis;\n4. Patient has granuloma or non-curetted cyst;\n5. Patient has an history of uncontrolled diabetes;\n6. Patient is alcoholic and\u002For heavy smoker (\\> 20 cigarettes per day);\n7. Patient has a congenital or acquired immunodeficiency;\n8. Patient has severe bone loss (≥ 40cm3);\n9. Patient is on long-term steroidal therapy or treatment acting on the calcium or phosphorus metabolism;\n10. Patient is or has been scheduled for surgery that would involve intra-articular implantation of the study device;\n11. Patient who has or had an uncontained bone defect created as a result of trauma injury or surgically created;\n12. Patient was exposed to any radiation (e.g. X-Rays, handling of radiolabelled materials) other than the normal background radiation within the 12 months before the screening visit;\n13. Patient is pregnant;\n14. Patient who is an employee at the study site;\n15. Patient is known to be non-compliant with medical treatment or follow-up\n16. Patient has any significant or unstable medical\u002Fpsychiatric condition that, in the opinion of the Investigator, would interfere with their ability to participate in the study;\n17. Patient is currently enrolled or planning to enrol in another clinical study or treatment with another investigational drug\u002Fdevice that may interfere with the assessments, visits or outcomes of this study.","85 Years",{"count":95,"type":21},100,"Study of the osteoconductive potential of the injectable bone substitute In'Oss™ (MBCP® Putty) in the filling of orthopaedic bone defects to collect Post-Market Clinical Follow-up (PMCF) data for the CE-marked In'Oss™ (MBCP® Putty) device in the orthopaedic trauma surgery",[98,99,29],"Orthopedic Disorder","Trauma Injury",[101,102,103,104,105,106,107,108],"Proximal humerus","Distal radius","Distal femur","Proximal tibia","Distal tibia","Fracture","MBCP Putty","Bone defect reconstruction","NOT_YET_RECRUITING","2025-02-03",{"date":112,"type":44},"2025-02-05",{"date":114,"type":21},"2025-03",{"date":116,"type":21},"2027-03",{"name":118,"class":119},"Advanced Medical Solutions Ltd.","INDUSTRY"]