[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"eye-movement-desensitization-and-reprocessing\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:eye-movement-desensitization-and-reprocessing":29},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,4,0,[8,48,77,107],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":13,"acronym":14,"eligibilityCriteria":15,"healthyVolunteers":11,"sex":16,"minAge":17,"maxAge":18,"enrollmentInfo":19,"targetDuration":4,"studyType":22,"phases":23,"briefSummary":25,"conditions":26,"keywords":30,"overallStatus":35,"whyStopped":4,"lastUpdateSubmitDate":36,"lastUpdatePostDateStruct":37,"startDateStruct":40,"completionDateStruct":42,"leadSponsor":44,"locationsCount":47},"100414125","emdr-treatment-in-ptsd-following-cardiac-events-100414125",false,"NCT04672551","EMDR Treatment in PTSD Following Cardiac Events","EMDR_PTSD_MI","Inclusion Criteria:\n\n* Age between 18-70 years\n* Men or women\n* STEMI (irrespective of troponin, but ST-elevation) or non-STEMI (troponin positive) at the time of the cardiac event, as verified by the cardiologist\n* Diagnosis of PTSD caused by the cardiac event\n\nExclusion Criteria:\n\n* Psychotic disorder, bipolar disorder, substance abuse as measured with the Mini International Neuropsychiatric Interview (M.I.N.I)\n* Acute suicidal ideation as assessed with the M.I.N.I.\n* Non-selective beta blockers (e.g., propranolol) during the study period\n* Ongoing psychological\u002Fpsychiatric treatment outside of the trial during the study period\n* Visionary problems, e.g. strabismus, which does not allow adequate eye movements\n* Insufficient knowledge of the German language\n* Expected inability or willingness to follow the study protocol\n* Regular medication with benzodiazepine","ALL","18 Years","70 Years",{"count":20,"type":21},60,"ESTIMATED","INTERVENTIONAL",[24],"NA","Cardiac events can often result in debilitating and persistent psychological symptoms. A key question involves whether optimal treatment of cardiac-induced posttraumatic stress disorder (PTSD) reduces PTSD symptoms and thereby may offset the risk of recurrent or worsening cardiovascular disease. Cardiac-induced PTSD 1) is prevalent, 2) features symptoms unique to internal ongoing somatic threat, with fears and worries that can be distinguished from PTSD resulting from external causes, 3) is persistent, 4) is associated with negative physical and emotional consequences, and 5) has not been the subject of randomized-controlled treatment trials (RCT). There is preliminary evidence suggesting that patients with cardiac-disease induced PTSD might particularly profit from EMDR. Nevertheless, this possibility has not been tested in cardiac-induced PTSD. Currently, patients with cardiac-induced PTSD are not routinely offered trauma-focused therapies, with a lack of scientific evidence likely being one major reason for this omission. If our proposed RCT shows that EMDR can be an effective treatment for patients with ACS-induced PTSD, EMDR could be routinely implemented as first-line treatment. The RCT outcomes might inform larger trials to test whether poor prognosis in terms of major adverse cardiovascular events can be improved through EMDR in patients with cardiac-induced PTSD.",[27,28,29],"Posttraumatic Stress Disorder","Myocardial Infarction","Eye Movement Desensitization and Reprocessing",[31,32,33,34],"PTSD","MI","ACS","EMDR","RECRUITING","2026-05-06",{"date":38,"type":39},"2026-05-07","ACTUAL",{"date":41,"type":39},"2020-11-21",{"date":43,"type":21},"2027-11-30",{"name":45,"class":46},"University of Zurich","OTHER",1,{"id":49,"slug":50,"hasResults":11,"nctId":51,"briefTitle":52,"officialTitle":53,"acronym":4,"eligibilityCriteria":54,"healthyVolunteers":11,"sex":16,"minAge":17,"maxAge":55,"enrollmentInfo":56,"targetDuration":4,"studyType":22,"phases":58,"briefSummary":59,"conditions":60,"keywords":4,"overallStatus":35,"whyStopped":4,"lastUpdateSubmitDate":68,"lastUpdatePostDateStruct":69,"startDateStruct":71,"completionDateStruct":73,"leadSponsor":75,"locationsCount":47},"100552149","theories-of-working-memory-and-consolidationreconsolidation-in-the-process-of-resorption-of-post-traumatic-symptoms-100552149","NCT06469333","Theories of Working Memory and Consolidation\u002FRECOnsolidation in the Process of Resorption of Post-traumatic Symptoms.","Theories of Working Memory and Consolidation\u002FRECOnsolidation in the Process of Resorption of Certain Post-traumatic Symptoms: Interventional, Randomized Single-center Study","Inclusion Criteria:\n\n* Present symptoms of acute stress (score between 22 and 35 on the Impact Event Scale-Revised, IES-R) and\u002For PTSD (higher score or equal to 36 on the IES-R), but at least present moderate to high psychological distress (score equal to or greater than 8 on the Kessler Abbreviated Psychological Distress Scale, K6);\n* Being in need of psychotherapeutic follow-up but not having started it yet;\n* Be aged between 18 and 65 years inclusive;\n* Speak and write French (be able to understand information and complete questionnaires independently);\n* Have good vision (being able to follow the movement of a white point on a screen);\n* Have good hearing and tactile abilities (being able to perceive auditory and tactile tones);\n* Have a computer equipped with a webcam;\n* Be informed and sign informed consent.\n\nExclusion Criteria:\n\n* Be an adult protected under guardianship or curatorship;\n* Be a person subject to a judicial safeguard measure;\n* Present a lack of autonomy implying an impossibility in terms of administering questionnaires and filling out questionnaires;\n* Have a vision defect implying an impossibility of visual tracking of a white dot;\n* Present a hearing defect and\u002For tactile abilities implying an impossibility of perception;\n* Have a neurological condition constituting measurement biases (muscular dysfunctions, perceptual dysfunctions, etc.);\n* Suffer from psychotraumatic and dissociative disorders of complex type (respectively evaluated with regard to the anamestistic data of the patients and with a score greater than 25 on the dissociative experiences scale (Dissociative Experiences Scale, DES);\n* Do not present psychological distress (score less than 8 on the Kessler Abbreviated Psychological Distress Scale, K6) ;\n* Have a drug or alcohol dependence;\n* Benefit from ongoing psychotherapeutic monitoring;\n* Have already benefited from psychotherapeutic follow-up or have participated in studies in the last 6 months, both involving EMDR therapy.","65 Years",{"count":57,"type":21},150,[24],"EMDR is a psychotherapeutic approach recommended by the World Health Organization (WHO) for the treatment of disorders such as post-traumatic stress disorder, anxiety, depression and, more generally, psychological distress. In all these disorders, intrusions are one of the symptoms leading to intense emotional distress. EMDR therapy, by making intrusions less emotional and less present in the mind (i.e. less vivid), would reduce psychological distress. This symptomatological reduction would be made possible by the therapist's application of alternating bilateral visual (rapid eye movements following a point from left to right), auditory (tones emitted alternately in the right ear and then in the left ear) and\u002For tactile (tapping with fingers on the left and right shoulders alternately) stimulations administered while the patient concentrates on his or her intrusive thoughts. Accordingly, the aim of this research is to investigate the efficacy of self-administration of Alternating Bilateral Stimulations (ABS), on the emotional intensity (emotionality) associated with negative intrusive thoughts (or intrusions).",[61,62,29,63,64,65,66,67],"Working Memory","Consolidation\u002FRecconsolidation Memory","Alterning Bilateral Stimulation","Stress Disorders, Post-Traumatic","Intrusive Memories","Vividness","Emotivity","2025-11-20",{"date":70,"type":39},"2025-11-26",{"date":72,"type":39},"2024-09-06",{"date":74,"type":21},"2026-06",{"name":76,"class":46},"University of Lorraine",{"id":78,"slug":79,"hasResults":11,"nctId":80,"briefTitle":81,"officialTitle":81,"acronym":82,"eligibilityCriteria":83,"healthyVolunteers":11,"sex":16,"minAge":17,"maxAge":4,"enrollmentInfo":84,"targetDuration":4,"studyType":22,"phases":86,"briefSummary":87,"conditions":88,"keywords":92,"overallStatus":35,"whyStopped":4,"lastUpdateSubmitDate":97,"lastUpdatePostDateStruct":98,"startDateStruct":100,"completionDateStruct":102,"leadSponsor":104,"locationsCount":106},"100575057","emdr-for-fear-of-cancer-recurrence-in-patients-with-familial-melanoma-a-waiting-list-control-trial-100575057","NCT06767332","EMDR for Fear of Cancer Recurrence in Patients with Familial Melanoma: a Waiting List Control Trial","FAME","Inclusion Criteria:\n\n* a score of 16 or higher on the FCRI-NL-SF\n* 18 years or older\n* diagnosed with familial melanoma\n\nExclusion Criteria:\n\n* insufficient knowledge of the Dutch language.\n* acute psychiatric disease (psychosis, suicidal ideation)\n* variable dosis of anxiolytics",{"count":85,"type":21},30,[24],"High fear of cancer recurrence (FCR) impacts patient's quality of life (QoL) and is prevalent among patients with familial melanoma. The main objective is to investigate whether EMDR is effective in treating high FCR in patients with familial melanoma. The study design is a non-blinded, randomized waiting-list controlled trial. Patients aged 18 years or older with familial melanoma can be included. Patients with high FCR will receive a maximum of 4, 90 minutes, EMDR-sessions. The main study parameter is the decrease and level of FCR measured with the Cancer Worry Scale (CWS). The secondary study parameter is quality of life, measured with the EORTC.",[89,90,29,91],"Familial Melanoma","Fear of Cancer Recurrence","Psychological Intervention",[34,90,89,29,93,94,95,96],"Psychological intervention","Anxiety","Psycho-oncology","FCR","2025-01-08",{"date":99,"type":39},"2025-01-09",{"date":101,"type":39},"2023-11-01",{"date":103,"type":21},"2025-12-31",{"name":105,"class":46},"Leiden University Medical Center",2,{"id":108,"slug":109,"hasResults":11,"nctId":110,"briefTitle":111,"officialTitle":112,"acronym":4,"eligibilityCriteria":113,"healthyVolunteers":11,"sex":16,"minAge":17,"maxAge":4,"enrollmentInfo":114,"targetDuration":4,"studyType":22,"phases":116,"briefSummary":117,"conditions":118,"keywords":4,"overallStatus":35,"whyStopped":4,"lastUpdateSubmitDate":124,"lastUpdatePostDateStruct":125,"startDateStruct":127,"completionDateStruct":129,"leadSponsor":131,"locationsCount":47},"100569215","effectiveness-of-trauma-treatment-in-the-specialist-health-care-services-100569215","NCT06691347","Effectiveness of Trauma Treatment in the Specialist Health Care Services","Towards Evidence-based PTSD Care in Norwegian Specialist Health Services - A Randomized Controlled Trial","Inclusion Criteria:\n\n* age ≥18 years\n* meeting criteria for PTSD based on the Clinician-Administered PTSD Scale for DSM-5 (CAPS-5) with a total score ≥23\n\nExclusion Criteria:\n\n* insufficient mastery of the Norwegian language\n* severe intellectual impairment (estimated IQ of 70 or less)\n* comorbid psychiatric illnesses in an acute phase where other types of treatment need to be prioritized (e.g. hospitalization)\n* history of EMDR or CT-PTSD treatment",{"count":115,"type":21},270,[24],"Post-traumatic stress disorder (PTSD) is a common mental illness. Treatments for PTSD are regarded as highly effective, but a large-scale, prospective, longitudinal randomized controlled trial comparing the effectiveness of these treatments has been requested by the research community. This study aims to conduct a comprehensive investigation into the effectiveness of two prominent PTSD therapies, eye movement desensitization and reprocessing (EMDR) and cognitive therapy for PTSD (CT-PTSD), within the Norwegian specialist health care services. The study aims to compare the therapy effectiveness, including their impact on comorbid disorders, complex PTSD symptoms, and functional outcomes post-treatment. Patients will be randomly assigned to EMDR or CT-PTSD and given manualized therapy aligned with their treatment goals. Each arm aims to recruit 135 patients, resulting in a total sample size of 270 patients.\n\nThe main objective of this study is to examine the growth curves of the two methods and how patient characteristics affect their developments. Secondary short-term aims include (1) investigating the impact of EMDR and CT-PTSD on complex PTSD symptoms, (2) assessing effects on other clinical conditions and functional outcomes, and (3) exploring whether the therapeutic alliance mediates treatment effects. Secondary long-term aims are (1) to assess the long-term effects of EMDR and CT-PTSD on PTSD symptoms and (2) to explore the impact of extended or additional treatments on outcomes.",[119,120,121,122,29,123],"Post Traumatic Stress Disorder PTSD","Quality of Life","Functional Outcome","Complex Post-Traumatic Stress Disorder","Cognitive Therapy","2024-11-13",{"date":126,"type":39},"2024-11-15",{"date":128,"type":39},"2024-09-26",{"date":130,"type":21},"2030-12",{"name":132,"class":46},"Vestre Viken Hospital Trust"]