[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"face\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:face":27},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,3,0,[8,46,77],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":13,"acronym":14,"eligibilityCriteria":15,"healthyVolunteers":11,"sex":16,"minAge":17,"maxAge":4,"enrollmentInfo":18,"targetDuration":4,"studyType":21,"phases":22,"briefSummary":24,"conditions":25,"keywords":30,"overallStatus":33,"whyStopped":4,"lastUpdateSubmitDate":34,"lastUpdatePostDateStruct":35,"startDateStruct":38,"completionDateStruct":40,"leadSponsor":42,"locationsCount":45},"100452889","efficacy-of-a-personalized-rehabilitation-program-of-facial-involvement-in-systemic-sclerosis-100452889",false,"NCT05177380","Efficacy of a Personalized Rehabilitation Program of Facial Involvement in Systemic Sclerosis","PREVISS","Inclusion Criteria:\n\n* Age ≥ 18 yo\n* Systemic sclerosis according to the 2013 ACR\u002FEULAR (American College of Rheumatology) classification criteria\n* Systemic sclerosis with facial involvement defined by a MHISS score \\> 6\n* Immunosuppressive and\u002For anti-fibrosis treatment stable for at least 1 month\n* Subject able to understand the objectives and risks of research and to give informed consent\n* Subject enrolment in the health insurance scheme\n\nExclusion Criteria:\n\n* Pregnancy\n* Previous participation in a rehabilitation program of facial involvement\n* Patient under legal protection\n* Impossibility to give clear information of subject","ALL","18 Years",{"count":19,"type":20},60,"ESTIMATED","INTERVENTIONAL",[23],"NA","Systemic sclerosis is a rare autoimmune disorder characterized by microangiopathy, activation of the immune system, and sclerosis of tissues including the skin. Facial involvement is frequent and disabling. It causes significant functional and aesthetic discomfort, and a major deterioration in quality of life. It results in a loss of suppleness of the skin and subcutaneous tissues, dysfunction of the temporomandibular joint, peribuccal rhagades, microstomia, and dry mouth causing difficulties in mouth opening, feeding, dental care, and weight loss.\n\nFacial involvement in systemic sclerosis can be assessed using the Mouth Handicap in Systemic Sclerosis (MHISS) score, a validated patient questionnaire assessing the functional and aesthetic consequences of systemic sclerosis on the face.\n\nAlthough common and disabling, facial involvement is underestimated and poorly managed. Immunosuppressive and\u002For anti-fibrosis drugs are not very effective. Facial rehabilitation could significantly improve the mouth handicap but facial rehabilitation is not currently performed in standard care in systemic sclerosis patients.\n\nThe aim of the study is to evaluate the efficacy of a personalized rehabilitation program vs standard care in facial involvement of systemic sclerosis patients.",[26,27,28,29],"Systemic Sclerosis","Face","Facial Involvement","Rehabilitation",[27,31,29,32],"Facial involvement","Systemic sclerosis","RECRUITING","2026-06-05",{"date":36,"type":37},"2026-06-08","ACTUAL",{"date":39,"type":37},"2022-10-13",{"date":41,"type":20},"2029-12",{"name":43,"class":44},"University Hospital, Strasbourg, France","OTHER",1,{"id":47,"slug":48,"hasResults":11,"nctId":49,"briefTitle":50,"officialTitle":51,"acronym":52,"eligibilityCriteria":53,"healthyVolunteers":11,"sex":16,"minAge":17,"maxAge":4,"enrollmentInfo":54,"targetDuration":4,"studyType":21,"phases":56,"briefSummary":57,"conditions":58,"keywords":63,"overallStatus":33,"whyStopped":4,"lastUpdateSubmitDate":68,"lastUpdatePostDateStruct":69,"startDateStruct":71,"completionDateStruct":73,"leadSponsor":75,"locationsCount":45},"100356853","evaluation-of-the-effectiveness-of-hypnosis-support-on-patient-perception-of-outpatient-surgery-under-local-anaesthesia-100356853","NCT03926403","Evaluation of the Effectiveness of Hypnosis Support on Patient Perception of Outpatient Surgery Under Local Anaesthesia","Evaluation of the Effectiveness of Hypnosis Support on Patient Perception of Outpatient Surgery Under Local Anaesthesia in the Maxillo-Facial Surgery Department of the CHU Amiens-Picardie.","HYPNOFACE","Inclusion Criteria:\n\n* Patient treated under local anaesthesia in the Maxillo Facial Surgery department with ultra-short circuit\n* Patient undergoing face surgery\n* Patient who has received appropriate information and has provided informed consent\n* Adult patient ≥ 18 years old\n* Patient with a score of ≥ 36 on the initial anxiety self-assessment questionnaire\n\nExclusion Criteria:\n\n* Patient under general anaesthesia\n* Patients treated in conventional inpatient care or in the traditional ambulatory circuit\n* Patient under guardianship or trusteeship\n* Minor patient \\\u003C 18 years of age\n* Patient who has not provided informed consent or who cannot submit to the study protocol\n* Patient suffering from cognitive disorders (ex: Alzheimer's disease)\n* Patients who are deaf or hearing-impaired",{"count":55,"type":20},66,[23],"Many clinical trials assessing the effectiveness of hypnosis have been conducted in recent years, some of which show that hypnosis reduces pain perception better than drug treatments administered to control groups, and that it is at least as effective as other complementary therapies (such as massage, acupuncture, yoga). However, their conclusions are limited by a significant risk of bias, and further studies with rigorous methodology remain necessary. The hypothesis of this study is that hypnosis support methods can reduce anxiety in patients requiring facial surgery under local anaesthesia, and thus improve their medical management.\n\nThe purpose of this study is to evaluate the effectiveness of hypnosis support on the patient's state of anxiety before and after outpatient surgery under local anaesthesia in the Maxillofacial Surgery Department.",[59,60,61,62],"Hypnosis","Local Anaesthesia","Outpatient Surgery","FACE",[64,65,66,67],"hypnosis","local anaesthesia","outpatient surgery","face surgery","2026-05-12",{"date":70,"type":37},"2026-05-13",{"date":72,"type":37},"2020-01-28",{"date":74,"type":20},"2027-10",{"name":76,"class":44},"Centre Hospitalier Universitaire, Amiens",{"id":78,"slug":79,"hasResults":11,"nctId":80,"briefTitle":81,"officialTitle":81,"acronym":4,"eligibilityCriteria":82,"healthyVolunteers":83,"sex":16,"minAge":17,"maxAge":4,"enrollmentInfo":84,"targetDuration":4,"studyType":86,"phases":4,"briefSummary":87,"conditions":88,"keywords":4,"overallStatus":33,"whyStopped":4,"lastUpdateSubmitDate":92,"lastUpdatePostDateStruct":93,"startDateStruct":95,"completionDateStruct":97,"leadSponsor":99,"locationsCount":5},"100614291","ai-facial-analysis-algorithm-to-screening-coronary-artery-disease-in-high-risk-community-population-100614291","NCT07277686","AI Facial Analysis Algorithm to Screening Coronary Artery Disease in High-Risk Community Population","Inclusion Criteria:\n\n* Age \\>= 18 years.\n* Community high-risk population, defined as individuals meeting at least one of the following criteria:\n\n  1. Diagnosed with Diabetes Mellitus;\n  2. Diagnosed with Hypertension;\n  3. Advanced age (\\> 65 years old).\n\nExclusion Criteria:\n\n* Prior confirmed diagnosis of Coronary Heart Disease (CAD), including clinically diagnosed CAD, history of Coronary Artery Bypass Grafting (CABG), or history of Percutaneous Coronary Intervention (PCI).\n* History of diagnosed Heart Failure.\n* Significant facial alterations or conditions that may interfere with AI image analysis, such as plastic surgery, severe facial trauma, or heavy makeup.\n* Refusal to participate in the study.",true,{"count":85,"type":20},1392,"OBSERVATIONAL","This study aims to evaluate the effectiveness of this facial image-based AI algorithm for screening CAD in high-risk community populations (specifically individuals with diabetes, hypertension, or aged over 65). The main objectives are:\n\n1. To verify if the AI algorithm can accurately distinguish between high-risk and low-risk groups by comparing the actual prevalence of CAD in these groups.\n2. To compare the CAD detection rate using this AI screening strategy against the natural detection rate in a real-world cohort.",[89,90,27,91],"Coronary Artery Disease (CAD)","Artificial Intelligence Algorithms","Screening","2026-01-01",{"date":94,"type":37},"2026-01-06",{"date":96,"type":37},"2025-12-11",{"date":98,"type":20},"2026-08-01",{"name":100,"class":101},"China National Center for Cardiovascular Diseases","OTHER_GOV"]