[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"facet-joint-arthropathy\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:facet-joint-arthropathy":26},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,3,0,[8,41,74],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":4,"eligibilityCriteria":15,"healthyVolunteers":11,"sex":16,"minAge":17,"maxAge":18,"enrollmentInfo":19,"targetDuration":22,"studyType":23,"phases":4,"briefSummary":24,"conditions":25,"keywords":4,"overallStatus":28,"whyStopped":4,"lastUpdateSubmitDate":29,"lastUpdatePostDateStruct":30,"startDateStruct":33,"completionDateStruct":35,"leadSponsor":37,"locationsCount":40},"100643490","association-between-trendelenburg-sign-and-lumbar-mri-abnormalities-100643490",false,"NCT07629466","Association Between Trendelenburg Sign and Lumbar MRI Abnormalities","Association of the Trendelenburg Sign With Spinopelvic Biomechanics and Lumbar MRI Abnormalities\"","Inclusion Criteria:\n\n* Age between 18 and 65 years.\n* Patients who have previously presented to the clinic with a complaint of low back pain.\n* Willingness and ability to provide written informed consent for participation in the study.\n* Availability of lumbar MRI images obtained within the previous 12 months and accessible for evaluation.\n\nExclusion Criteria:\n\n* Presence of red flag conditions associated with low back pain, including malignancy, infection, acute trauma, or significant neurological deficits.\n* History of lumbar spine surgery.\n* Structural spinal anomalies such as sacralization or lumbarization.\n* Spinal deformities, including scoliosis.\n* Rheumatologic diseases affecting the spine (e.g., axial spondyloarthritis).\n* Significant radiculopathy or advanced neurological deficits, and the presence of extruded or sequestrated lumbar disc herniation.\n* Clinically significant lumbar spinal stenosis.\n* Spondylolysis and\u002For spondylolisthesis.\n* Acute vertebral fracture, compression fracture, or recent fracture associated with severe osteoporosis.\n* Hip or pelvic conditions that may directly influence the Trendelenburg sign, including: History of hip arthroplasty or hip surgery, advanced hip osteoarthritis, residual deformity following lower-extremity fracture, significant leg length discrepancy (\\>2 cm).\n* Systemic or neuromuscular disorders, including multiple sclerosis, myopathies, amyotrophic lateral sclerosis (ALS), stroke, or peripheral neuropathies.\n* Pregnancy.\n* Severe knee or ankle pathology or other conditions causing substantial gait impairment.","ALL","18 Years","65 Years",{"count":20,"type":21},120,"ESTIMATED","1 Day","OBSERVATIONAL","The Trendelenburg sign is a common clinical finding indicating hip abductor dysfunction and altered pelvic stability. The relationship between the Trendelenburg sign, spinopelvic biomechanics, hip muscle strength, and lumbar magnetic resonance imaging (MRI) abnormalities remains insufficiently understood. This study aims to investigate the association between Trendelenburg sign positivity and lumbar MRI findings, including facet arthropathy, ligamentum flavum hypertrophy, multifidus muscle morphology, and psoas muscle characteristics, as well as spinopelvic biomechanical parameters and hip abductor muscle strength.",[26,27],"Facet Joint Arthropathy","Lower Back Pain","NOT_YET_RECRUITING","2026-06-09",{"date":31,"type":32},"2026-06-10","ACTUAL",{"date":34,"type":21},"2026-06-04",{"date":36,"type":21},"2026-10-10",{"name":38,"class":39},"Bahçeşehir University","OTHER",1,{"id":42,"slug":43,"hasResults":11,"nctId":44,"briefTitle":45,"officialTitle":46,"acronym":4,"eligibilityCriteria":47,"healthyVolunteers":11,"sex":16,"minAge":17,"maxAge":48,"enrollmentInfo":49,"targetDuration":4,"studyType":51,"phases":52,"briefSummary":54,"conditions":55,"keywords":58,"overallStatus":64,"whyStopped":4,"lastUpdateSubmitDate":65,"lastUpdatePostDateStruct":66,"startDateStruct":68,"completionDateStruct":70,"leadSponsor":72,"locationsCount":40},"100590287","trans-arterial-embolization-for-the-treatment-of-facet-pain-due-to-facet-arthropathy-100590287","NCT06965452","Trans-arterial Embolization for the Treatment of Facet Pain Due to Facet Arthropathy","Trans Arterial Embolization for Facet Arthropathy","Inclusion Criteria:\n\n* Age 18-85\n\n  * Confirmed diagnosis of spinal facet arthropathy on MRI OR CT\n  * Confirmed diagnosis of lumbosacral facetogenic pain based on diagnostic nerve blocks.\n  * Failed medical management of pain.\n\n    * Back pain persistent for at least 6 months\n    * Pain worse than at least 6\u002F10 on a visual analog pain scale\n  * Failed at least one of either intra-articular injections of steroids\u002F anesthetics or neuro-ablative procedure.\n  * Maximum of 2 spinal levels of facetogenic pain in the lumbar and sacral spine (i.e. L4-5 and L5-S1).\n  * Modified Rankin Scale 0-2\n\nExclusion Criteria:\n\n* \\- Pregnancy\n* History of prior spinal embolization at the target level.\n* History of surgery\u002F stenting of the aorta at the level of embolization.\n* Severe allergic reaction to iodinated contrast (i.e. anaphylaxis)\n* Creatinine \\> 1.5 mg\u002Fdl and\u002For creatinine clearance \\\u003C 60 mL\u002Fmin (except if patients is already on hemodialysis).\n* Modified Rankin Scale \\>2\n* Angiographic\u002F Procedural Exclusion Criterion: Vascular supply to the spinal cord from the vessels supplying the facet joints targeted for embolization.","85 Years",{"count":50,"type":21},40,"INTERVENTIONAL",[53],"NA","This single-site, single-arm study evaluates the feasibility, safety, tolerability, and efficacy of trans-arterial embolization (TAE) using Embozene microparticles for treating facetogenic pain due to facet arthropathy (osteoarthritis of the facet joints) in the lumbar spine.",[26,56,57],"Pain","Osteoarthritis",[59,60,61,62,63],"Facetogenic pain","Facet pain","Facet joint pain","Low back pain","Back Pain","RECRUITING","2025-08-14",{"date":67,"type":32},"2025-08-19",{"date":69,"type":32},"2025-08-12",{"date":71,"type":21},"2026-08-01",{"name":73,"class":39},"Northwell Health",{"id":75,"slug":76,"hasResults":11,"nctId":77,"briefTitle":78,"officialTitle":79,"acronym":80,"eligibilityCriteria":81,"healthyVolunteers":11,"sex":16,"minAge":17,"maxAge":4,"enrollmentInfo":82,"targetDuration":4,"studyType":23,"phases":4,"briefSummary":84,"conditions":85,"keywords":88,"overallStatus":64,"whyStopped":4,"lastUpdateSubmitDate":92,"lastUpdatePostDateStruct":93,"startDateStruct":95,"completionDateStruct":97,"leadSponsor":99,"locationsCount":40},"100567608","prospective-evaluation-of-therapeutic-combination-in-treating-vertebral-compression-fractures-100567608","NCT06670404","Prospective Evaluation of Therapeutic Combination in Treating Vertebral Compression Fractures","PROTECT - Prospective Evaluation of Therapeutic Combination in Treating Vertebral Compression Fractures","PROTECT","Inclusion Criteria:\n\n* Patients \\>18 years.\n* Patients requiring vertebroplasty for the fixation of symptomatic pathological fractures of the thoracic or lumbar vertebral body resulting from osteoporosis or tumor.\n* Symptomatic vertebral compression fracture(s) confirmed by MRI with bone marrow oedema on T2\u002FSTIR sequences.\n* Diagnosis of osteoporosis (clinically and confirmed on DXA with quantifiable BMD) or pathological fracture due to tumor\n* Patients with 1 or more vertebral compression fractures of the thoracic or lumbar spine Note: Patients with a current vertebral compression fracture who also have a previous history of vertebral compression fractures of the thoracic or lumbar spine may be included.\n\nStudy Specific Inclusion Criterion • Signed informed consent\n\nExclusion Criteria:\n\n* Infection\n* Vertebral body collapse to less than 1\u002F3 (33%) of original height\n* Vertebral plana (\\>90% vertebral body collapse)\n* Spinal stenosis (retro pulsed fragments).\n* Unstable spine warranting surgical stabilization\n* Prophylactic treatment of any vertebrae with vertebroplasty\n* Irreversible life threating bleeding disorders\n* End stage kidney disease\n* Drug dependence (IVDU)\n* Pregnancy\n\nStudy Specific Exclusion Criterion:\n\n• Unable or unwilling to follow the standard of care prescribed follow-up visits",{"count":83,"type":21},130,"The purpose of this study is to collect clinical and radiographic outcomes in patients undergoing vertebroplasty procedures for the treatment of osteoporotic or pathological fractures of the vertebral body to understand the role of sagittal balance in patient outcomes. To support this objective, the sagittal balance measurement of sagittal vertical axis (SVA), NRS back pain, Quebec Back Pain Disability Scale (Quebec) score, and complications will be collected. The secondary purpose of the study is to review the role of sagittal balance and adjacent facet joint arthropathy treatment in patients with vertebral body fractures due to osteoporosis or tumor.",[86,87,26],"Vertebral Compression Fractures","Pathological Fracture",[89,90,91],"vertebroplasty","CONFIDENCE High Viscosity Spinal Cement","observational post-market study","2025-02-13",{"date":94,"type":32},"2025-02-17",{"date":96,"type":32},"2024-11-06",{"date":98,"type":21},"2026-12-31",{"name":100,"class":39},"Prof Nicolas Theumann"]