[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"facial-asymmetry\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:facial-asymmetry":32},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,4,0,[8,49,85,118],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":15,"eligibilityCriteria":16,"healthyVolunteers":11,"sex":17,"minAge":18,"maxAge":19,"enrollmentInfo":20,"targetDuration":4,"studyType":23,"phases":24,"briefSummary":26,"conditions":27,"keywords":34,"overallStatus":36,"whyStopped":4,"lastUpdateSubmitDate":37,"lastUpdatePostDateStruct":38,"startDateStruct":41,"completionDateStruct":43,"leadSponsor":45,"locationsCount":48},"100641702","clinical-evaluation-of-patient-specific-3d-printed-titanium-implants-for-facial-reconstruction-100641702",false,"NCT07654647","Clinical Evaluation of Patient-Specific 3D-Printed Titanium Implants for Facial Reconstruction.","Evaluation of the Effectiveness of Patient-Specific 3D-Printed Titanium Facial Implants in the Reconstruction and Aesthetic Correction of Facial Defects: A Clinical Study","3DFACE","Inclusion Criteria:\n\n* Age 18 years or older.\n* Presence of facial bone defects resulting from cystic or tumoral osteolytic lesions.\n* Acquired or congenital facial deformities associated with bony defects or facial asymmetry.\n* Patients requiring patient-specific 3D-printed titanium implants for maxillofacial reconstruction.\n* Aesthetic indications requiring custom facial implant design, including microgenia (chin retrusion).\n* Ability to provide written informed consent.\n\nExclusion Criteria:\n\n* Active pathological lesions at the time of enrollment.\n* Age below 18 years.\n* History of radiotherapy within 12 months prior to enrollment.\n* Chronic untreated vitamin D deficiency.\n* Uncontrolled diabetes mellitus.\n* Inability or unwillingness to comply with follow-up requirements.","ALL","18 Years","60 Years",{"count":21,"type":22},30,"ESTIMATED","INTERVENTIONAL",[25],"NA","This clinical study aims to evaluate the effectiveness of patient-specific 3D-printed titanium facial implants in the reconstruction and aesthetic correction of facial defects. The study will include patients presenting with congenital, traumatic, or post-surgical facial deformities requiring reconstructive intervention.\n\nEligible participants will undergo preoperative clinical assessment and radiological imaging to design customized implants using computer-aided design (CAD) and 3D printing technology. The implants will be fabricated from medical-grade titanium and surgically placed according to standardized maxillofacial reconstructive protocols.\n\nPostoperative follow-up will assess functional outcomes, implant stability, complication rates, and aesthetic improvement over a defined observation period. Outcome evaluation will include clinical examination and patient-reported satisfaction measures.\n\nThe objective of this study is to determine whether patient-specific 3D-printed titanium implants provide reliable functional restoration and improved aesthetic outcomes in facial reconstruction compared to conventional reconstructive techniques.",[28,29,30,31,32,33],"Hemifacial Microsomia","Mucormycosis","Oral Squamous Cell Carcinoma","Microgenia","Facial Asymmetry","Fibrous Dysplasia",[35],"3D-Printed Titanium Implant * Facial Reconstruction","RECRUITING","2026-06-11",{"date":39,"type":40},"2026-06-17","ACTUAL",{"date":42,"type":40},"2026-04-26",{"date":44,"type":22},"2026-11-01",{"name":46,"class":47},"Tishreen University","OTHER",1,{"id":50,"slug":51,"hasResults":11,"nctId":52,"briefTitle":53,"officialTitle":54,"acronym":55,"eligibilityCriteria":56,"healthyVolunteers":57,"sex":17,"minAge":18,"maxAge":58,"enrollmentInfo":59,"targetDuration":4,"studyType":23,"phases":61,"briefSummary":62,"conditions":63,"keywords":66,"overallStatus":75,"whyStopped":4,"lastUpdateSubmitDate":76,"lastUpdatePostDateStruct":77,"startDateStruct":79,"completionDateStruct":81,"leadSponsor":83,"locationsCount":4},"100637084","effects-of-myofascial-release-therapy-on-body-posture-and-facial-symmetry-100637084","NCT07610200","Effects of Myofascial Release Therapy on Body Posture and Facial Symmetry","Effects of Myofascial Release Therapy on Body Posture and Facial Symmetry in Healthy Individuals: A Randomized Controlled Trial","MYOPOST-FACE","Inclusion Criteria:\n\n* Healthy individuals aged between 18 and 45 years\n* Ability to understand and follow study instructions\n* Independent performance of daily living activities\n* No regular physiotherapy or manual therapy treatment within the previous 3 months\n* Willingness to participate voluntarily and sign the informed consent form\n* Ability to attend assessment and intervention sessions regularly\n\nExclusion Criteria:\n\n* History of neurological or orthopedic disorders affecting posture or facial symmetry\n* Current musculoskeletal injury or ongoing rehabilitation treatment\n* Previous facial, spinal, or major musculoskeletal surgery or trauma\n* Pregnancy\n* Use of medications affecting muscle tone or neuromuscular function\n* Psychiatric or cognitive disorders limiting study participation\n* Inability to comply with study procedures",true,"45 Years",{"count":60,"type":22},60,[25],"This randomized controlled study aims to investigate the effects of myofascial release therapy on body posture and facial symmetry in healthy individuals. Postural disorders and fascial tension may lead to biomechanical alterations not only in the musculoskeletal system but also in facial soft tissues and symmetry. Myofascial release techniques are widely used in physiotherapy to improve fascial mobility, reduce tissue tension, and support postural alignment. However, the potential effects of these interventions on facial symmetry have not been sufficiently investigated.\n\nA total of 60 healthy participants will be included in the study and randomly assigned to either an intervention group or a control group. Participants in the intervention group will receive myofascial release therapy twice weekly for 6 weeks, while the control group will not receive any physical intervention during the same period. Body posture and facial symmetry assessments will be performed at baseline and after the intervention period.\n\nPostural assessment will be conducted using the PostureScreen Mobile application through standardized anterior, posterior, and lateral photographs. Facial symmetry will be evaluated using anthropometric facial landmarks identified on standardized facial photographs. Directional asymmetry scores, linear measurements, proportional analyses, and angular measurements will be calculated.\n\nThe study is expected to provide evidence regarding the relationship between fascial interventions, postural alignment, and facial symmetry, and may contribute to the development of new physiotherapy approaches targeting fascial and postural dysfunctions.",[64,32,65],"Postural Disorders","Myofascial Dysfunction",[67,68,69,70,71,72,73,32,65,74],"Myofascial Release Therapy","Posture","Facial Symmetry","Fascial System","Manual Therapy","Postural Alignment","Physiotherapy","Randomized Controlled Trial","NOT_YET_RECRUITING","2026-05-20",{"date":78,"type":40},"2026-05-27",{"date":80,"type":22},"2026-06-15",{"date":82,"type":22},"2027-12-01",{"name":84,"class":47},"Ece ACAR",{"id":86,"slug":87,"hasResults":11,"nctId":88,"briefTitle":89,"officialTitle":90,"acronym":4,"eligibilityCriteria":91,"healthyVolunteers":11,"sex":17,"minAge":18,"maxAge":4,"enrollmentInfo":92,"targetDuration":4,"studyType":23,"phases":94,"briefSummary":95,"conditions":96,"keywords":97,"overallStatus":36,"whyStopped":4,"lastUpdateSubmitDate":109,"lastUpdatePostDateStruct":110,"startDateStruct":112,"completionDateStruct":114,"leadSponsor":116,"locationsCount":48},"100593083","assessment-of-the-accuracy-of-patient-specific-plates-for-correction-of-maxillary-cant-in-facial-asymmetry-100593083","NCT07001826","Assessment of the Accuracy of Patient Specific Plates for Correction of Maxillary Cant in Facial Asymmetry","Assessment of the Accuracy of Patient Specific Plates for Correction of Maxillary Cant in Facial Asymmetry: A Prospective Clinical Trial","Inclusion Criteria:\n\nAge \\> 18 years\n\nPresence of maxillary cant\n\nPresence of facial asymmetry\n\nExclusion Criteria:\n\nDiagnosis of craniofacial syndrome\n\nHistory of maxillofacial tumors\n\nHistory of facial trauma\n\nPresence of cleft lip and\u002For palate",{"count":93,"type":22},8,[25],"The goal of this clinical trial is to learn how accurate patient-specific plates (PSPs) are for correcting a tilted upper jaw (maxillary cant) in people with facial asymmetry. The main questions it aims to answer are:\n\n* How closely does the actual surgery match the virtual surgical plan?\n* How satisfied are participants with how they look after surgery?\n\nResearchers will compare the surgery results using PSPs to the original 3D virtual plan to see how well they match.\n\nParticipants will:\n\n* Have a CT scan and 3D virtual surgery planning\n* Get custom-made plates designed to fit their upper jaw\n* Undergo surgery to correct the tilt of the upper jaw\n* Be followed for up to 6 months to check healing and results",[32],[98,99,100,101,102,103,104,105,106,107,108],"High-resolution CT scans","Computer-aided design (CAD)","Virtual surgical planning (VSP)","Orthognathic surgery","Asymmetrical mandibular deformities","Maxillary cant","LeFort I osteotomy","Bilateral sagittal split osteotomy (BSSO)","Patient-specific plates (PSPs)","3D superimposition","Patient satisfaction","2025-06-06",{"date":111,"type":40},"2025-06-11",{"date":113,"type":40},"2025-01-01",{"date":115,"type":22},"2027-01-01",{"name":117,"class":47},"Cairo University",{"id":119,"slug":120,"hasResults":11,"nctId":121,"briefTitle":122,"officialTitle":123,"acronym":4,"eligibilityCriteria":124,"healthyVolunteers":11,"sex":17,"minAge":125,"maxAge":4,"enrollmentInfo":126,"targetDuration":4,"studyType":128,"phases":4,"briefSummary":129,"conditions":130,"keywords":4,"overallStatus":75,"whyStopped":4,"lastUpdateSubmitDate":131,"lastUpdatePostDateStruct":132,"startDateStruct":133,"completionDateStruct":135,"leadSponsor":137,"locationsCount":48},"100593620","the-facial-muscular-activity-a-paradigm-for-understanding-facial-asymmetry-100593620","NCT07008807","The Facial Muscular Activity: A Paradigm for Understanding Facial Asymmetry","The Facial Muscular Activity: A Paradigm for Understanding Facial Asymmetry, A Prospective Correlation Study","Inclusion Criteria:\n\n* Presenting with noticeable facial asymmetry\n* Age \\> 16 years\n* General good health\n* Absence of specific neurological conditions affecting facial muscles.\n* Absence of congenital facial disorders that might cause facial asymmetry, like hemifacial microsomia and cleft lip and palate syndromes.\n\nExclusion Criteria:\n\n* History of facial trauma or surgery\n* Diagnosed Neuromuscular Disorders\n* Active facial infections.","16 Years",{"count":127,"type":22},100,"OBSERVATIONAL","Facial asymmetry, the degree to which the two sides of the face differ in size, shape, or the arrangement of features, is a near-universal human characteristic. The intricate network of facial muscles plays a crucial role in both the static structure and the dynamic expressions of the face. The continuous pull and action of facial muscles can influence the development and positioning of underlying soft tissues and even, over extended periods, potentially impact skeletal structures.",[32],"2025-05-29",{"date":109,"type":40},{"date":134,"type":22},"2025-06-01",{"date":136,"type":22},"2025-08-01",{"name":138,"class":47},"South Valley University"]