[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"facial-pain\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:facial-pain":27},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,3,0,[8,57,83],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":13,"acronym":14,"eligibilityCriteria":15,"healthyVolunteers":11,"sex":16,"minAge":17,"maxAge":4,"enrollmentInfo":18,"targetDuration":21,"studyType":22,"phases":4,"briefSummary":23,"conditions":24,"keywords":31,"overallStatus":44,"whyStopped":4,"lastUpdateSubmitDate":45,"lastUpdatePostDateStruct":46,"startDateStruct":49,"completionDateStruct":51,"leadSponsor":53,"locationsCount":56},"100603323","prospective-register-study-to-assess-eligibility-for-and-efficacy-of-surgical-treatment-in-patients-with-neurovascular-conflict-100603323",false,"NCT07135024","Prospective Register Study to Assess Eligibility for and Efficacy of Surgical Treatment in Patients With nEuRovascular Conflict","PETER registry","Inclusion Criteria:\n\n* suspected neurovascular conflict\n* signed consent for further use of routine clinical data as accepted by local regulations\n\nExclusion Criteria:\n\n* refusal of further use of routine clinical data","ALL","18 Years",{"count":19,"type":20},5001,"ESTIMATED","5 Years","OBSERVATIONAL","The aim of the registry is a multicenter, prospective long-term data collection of patients suspected neurovascular conflict and referred for possible microvascular decompression (Jannetta procedure). The registry relies exclusively on routinely collected clinical data, which are gathered in a standardized and privacy-compliant manner as part of everyday clinical practice. By systematically compiling this information across multiple centers, valuable insights into the effectiveness, potential side effects, and long-term outcomes of this surgical treatment can be gained. The registry will serve as a foundation for future scientific analyses and is intended to help answer relevant research questions regarding the treatment of trigeminal neuralgia based on solid evidence.",[25,26,27,28,29,30],"Trigeminal Neuralgia","Tic Douloureux","Facial Pain","Glossopharyngeal Neuralgia","Hemifacial Spasm","Neurovascular Conflict",[25,32,33,34,35,36,37,38,39,40,41,42,43],"Registry","prospective study","eligibility determination","efficacy, treatment","Follow-Up Studies","indication","microvascular decompression","Jannetta","tic douloureux","hemifacial spasm","neurovascular conflict","glossopharyngeal neuralgia","NOT_YET_RECRUITING","2025-08-13",{"date":47,"type":48},"2025-08-21","ACTUAL",{"date":50,"type":20},"2025-10-01",{"date":52,"type":20},"2033-10-01",{"name":54,"class":55},"Gerrit A Schubert","OTHER",2,{"id":58,"slug":59,"hasResults":11,"nctId":60,"briefTitle":61,"officialTitle":62,"acronym":4,"eligibilityCriteria":63,"healthyVolunteers":11,"sex":16,"minAge":64,"maxAge":65,"enrollmentInfo":66,"targetDuration":4,"studyType":68,"phases":69,"briefSummary":71,"conditions":72,"keywords":4,"overallStatus":44,"whyStopped":4,"lastUpdateSubmitDate":74,"lastUpdatePostDateStruct":75,"startDateStruct":77,"completionDateStruct":79,"leadSponsor":81,"locationsCount":4},"100595365","effects-of-photobiomodulation-with-superpulsed-laser-and-dual-wavelengths-in-children-and-adolescents-100595365","NCT07031505","Effects of Photobiomodulation With Superpulsed Laser and Dual Wavelengths in Children and Adolescents","Effects of Photobiomodulation With Superpulsed Laser and Dual Wavelength (810 + 980 NM) in Children and Adolescents With Facial Muscle Pain and Headache: Protocol for a Randomized Controlled Clinical Trial","Inclusion Criteria:\n\n* Children and adolescents 6 to 17 years of age enrolled at the medical and dental clinic of Universidade Nove de Julho (UNINOVE), Vergueiro Campus;\n* Children and adolescents who present with at least one symptom of orofacial pain and\u002For headache, according to the Faces Pain Scale and the childhood and adolescence headache questionnaire based on the ICHD-3\n\nExclusion Criteria:\n\n* Pregnant adolescents;\n* Having taken corticoids, non-steroidal anti-inflammatory drugs or analgesics in the previous 30 days;\n* Having taken isotretinoin;\n* Individuals who report photosensitivity to laser or LED in previous treatments.","6 Years","17 Years",{"count":67,"type":20},60,"INTERVENTIONAL",[70],"NA","This randomized clinical trial evaluates the effects of photobiomodulation with a superpulsed diode laser (810 + 980 nm) on orofacial pain and tension-type headache in children and adolescents. Sixty participants will be assigned to receive active PBM or sham therapy over eight sessions. Pain and anthropometric variables will be assessed.",[27,73],"Headache","2025-06-12",{"date":76,"type":48},"2025-06-22",{"date":78,"type":20},"2025-07-01",{"date":80,"type":20},"2026-04-30",{"name":82,"class":55},"University of Nove de Julho",{"id":84,"slug":85,"hasResults":11,"nctId":86,"briefTitle":87,"officialTitle":88,"acronym":4,"eligibilityCriteria":89,"healthyVolunteers":90,"sex":16,"minAge":91,"maxAge":92,"enrollmentInfo":93,"targetDuration":4,"studyType":22,"phases":4,"briefSummary":95,"conditions":96,"keywords":97,"overallStatus":101,"whyStopped":4,"lastUpdateSubmitDate":102,"lastUpdatePostDateStruct":103,"startDateStruct":105,"completionDateStruct":107,"leadSponsor":109,"locationsCount":111},"100555925","emotion-and-memory-in-chronic-neuropathic-pain-100555925","NCT06518421","Emotion and Memory in Chronic Neuropathic Pain","The Role of Limbic Subcortical Structures and Cognition in Chronic Neuropathic Pain","Inclusion Criteria (for HC and TN):\n\n* Age between 35 and 60 years old\n* Absence of other active major neurological or psychiatric disorders\n* Absence of MRI contraindications\n* Able to communicate sufficiently to complete tasks and questionnaires\n* Montreal Cognitive Assessment (MoCA) score greater than 23\u002F30 (MoCA ≤23\u002F30 could indicate severe cognitive impairment)\n\nInclusion Criteria for TN:\n\n* Experiencing TN pain over a period of 6 months\n* Stable medication use\n* Meet established diagnostic criteria for TN (ICHD-3)\n\nExclusion Criteria (both HC and TN):\n\n* Presence of other chronic pain\u002Fheadache conditions\n* Untreated hypertension or diabetes mellitus\n* History of chronic drug or substance use disorder, chronic use of opioids or steroids, head trauma affecting cognitive performance,\n* History\u002Fpresence of active psychiatric illness and\u002For current use of psychoactive medication\n* History of multiple sclerosis, skull base injury or tumours",true,"35 Years","60 Years",{"count":94,"type":20},400,"Chronic pain affects one in four Canadians, leading to severe personal and societal costs. Over 70% of chronic pain patients report memory difficulties and fear having unexpected pain. Abnormalities in brain structures associated with emotion and memory, including the hippocampus and amygdala, can be affected by chronic pain. Understanding the relationship between chronic pain, structural brain changes, and cognitive functioning will lead to improved diagnosis, treatment, and outcomes in chronic pain disorders. In this project, the investigators will use advanced brain imaging techniques that assess the structure and function of the brain along with cognitive assessments to examine the overlap between chronic pain and emotion-memory processes. The study team will conduct the study using an excellent model of chronic pain-trigeminal neuralgia, a severe form of facial pain that responds well to surgical treatment. Brain images and cognitive data will be collected from participants before and after surgical treatment for pain. This information will be analyzed and compared with age- and sex-matched healthy individuals. This study will be the first to thoroughly investigate relationships between brain structure and function, cognition (memory, emotion), and promises to impact our understanding of chronic neuropathic pain conditions.",[25,27],[25,27,98,99,100],"Emotion","Cognition","Memory","RECRUITING","2024-07-23",{"date":104,"type":48},"2024-07-24",{"date":106,"type":48},"2024-02-12",{"date":108,"type":20},"2029-02-12",{"name":110,"class":55},"University Health Network, Toronto",1]