[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"fall-patients\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:fall-patients":28},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,2,0,[8,46],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":15,"eligibilityCriteria":16,"healthyVolunteers":11,"sex":17,"minAge":18,"maxAge":4,"enrollmentInfo":19,"targetDuration":4,"studyType":22,"phases":4,"briefSummary":23,"conditions":24,"keywords":30,"overallStatus":33,"whyStopped":4,"lastUpdateSubmitDate":34,"lastUpdatePostDateStruct":35,"startDateStruct":38,"completionDateStruct":40,"leadSponsor":42,"locationsCount":45},"100605133","the-rhabdomyolysis-evaluation-in-the-emergency-department-reed-score-100605133",false,"NCT07158554","The Rhabdomyolysis Evaluation in the Emergency Department (REED) Score","The Rhabdomyolysis Evaluation in the Emergency Department (REED) Score - a Risk Prediction Model for Older Adults in the Emergency Department With Rhabdomyolysis After Prolonged Immobilisation (\"Long Lie\")","The REED Score","Inclusion Criteria:\n\nThe participants need to fulfil all three parts of the inclusion criteria:\n\n1. 60 years old or older at time of ED presentation\n2. Developed rhabdomyolysis (defined as CK \\>999U\u002FL)\n3. Have had a fall and been \u002F suspected to have been on the floor \u002F immobilised in one position for \\> 59 minutes.\n\nExclusion Criteria:\n\n1. Patient opted out of research studies via the National Data Opt Out (NDOO) Service.\n2. Principal Investigator (PI) had clinical input into patient care.\n3. Other causes of elevated creatine kinase (e.g. seizures, acute coronary syndromes, burns, myositis, muscular dystrophy, cardiac arrest)","ALL","60 Years",{"count":20,"type":21},1000,"ESTIMATED","OBSERVATIONAL","One in three adults over 65 fall annually, with one in five remaining on the floor for greater than one hour, which is referred to as a long lie. Pressure on the National Health Service has resulted in extended stays in the Emergency Department (ED) (sometimes longer than 12 hours) and prolonged ambulance response times. This impacts the older adults who have fallen and remain on the floor.\n\nThis project aims to develop a risk prediction model (RPM) for use within the ED to understand which older adults (60 years or older) who fall over and remain on the floor for longer than one hour (\"long lie\") and develop rhabdomyolysis (a serious condition where muscle breaks down and releases substances into the blood that can damage the kidneys) will develop poor outcomes and need admission to hospital for treatment and which patients can be safely discharged home.\n\nAim:\n\nTo develop a RPM to identify which older adults who have a fall and a long lie and attend the ED develop poor outcomes such as Acute kidney Injury (AKI) \\[kidneys suddenly stop working properly\\], needing kidney replacement therapy (KRT) \\[a treatment that helps kidneys that aren't working properly do their job of cleaning the blood\\] and mortality \\[death\\].\n\nObjectives:\n\n1. Abstract patient level data (e.g. biochemical, demographic, situational, medical history, medication history) from medical records combined with outcomes to understand which variables lead to poor outcomes such as AKI, needing KRT and mortality.\n2. Analyse the data using a statistical package (Statistical Package for Social Sciences \\[SPSS\\]) to develop a RPM with good discriminative abilities \\[how well the score can tell high-risk from low-risk patients\\].\n3. Demonstrate the ability of the RPM to identify which patients need admission to hospital with treatment and which patients can be safely discharged home.",[25,26,27,28,29],"Rhabdomyolysis","Death","Kidney Replacement Therapy","Fall Patients","Acute Kidney Injury",[15,25,31,32],"Emergency Department","Long Lie","NOT_YET_RECRUITING","2025-09-10",{"date":36,"type":37},"2025-09-17","ACTUAL",{"date":39,"type":21},"2025-10",{"date":41,"type":21},"2026-04",{"name":43,"class":44},"University of Salford","OTHER",1,{"id":47,"slug":48,"hasResults":11,"nctId":49,"briefTitle":50,"officialTitle":51,"acronym":52,"eligibilityCriteria":53,"healthyVolunteers":54,"sex":17,"minAge":18,"maxAge":4,"enrollmentInfo":55,"targetDuration":4,"studyType":57,"phases":58,"briefSummary":60,"conditions":61,"keywords":62,"overallStatus":33,"whyStopped":4,"lastUpdateSubmitDate":70,"lastUpdatePostDateStruct":71,"startDateStruct":73,"completionDateStruct":75,"leadSponsor":77,"locationsCount":45},"100550505","keep-exercising--stay-steady-development-and-feasibility-of-a-digital-health-intervention-to-encourage-exercise-maintenance-after-fall-prevention-exercise-programmes-end-100550505","NCT06447948","Keep Exercising & Stay Steady: Development and Feasibility of a Digital Health Intervention to Encourage Exercise Maintenance After Fall Prevention Exercise Programmes End.","Keep Exercising & Stay Steady (KESS): Development and Feasibility of a Digital Health Intervention to Encourage Exercise Maintenance After Fall Prevention Exercise Programmes End","KESS","Eligibility criteria:\n\n* Community dwelling older adults, aged over 60 years old.\n* Enrolled on a Healthworks FaME programme in the Northeast region of England.\n* Able to provide informed written consent.\n\nExclusion criteria:\n\n* Unable to independently walk 5 metres without a walking aid.\n* Advised by a medic not to undertake exercise.\n* Has a medical, cognitive, or physical condition that prevents safe engagement with digital technology or unsupervised exercise.",true,{"count":56,"type":21},40,"INTERVENTIONAL",[59],"NA","Falls and broken bones are a common health problem faced by older adults. Worldwide, one third of adults aged over 65 years old, and half of adults aged over 80 years, fall each year. One in five falls in older adults result in hospitalisation and one in twenty cause broken bones. Each year, 300,000 older adults break a bone following a fall which costs the UK £4.4billion in healthcare costs. Broken hip bones are the most serious outcome of a fall. One in twenty older adults will die and one in five need care assisted living following a hip fracture.\n\nMuscles and bones become weaker after 50 years of age which increases an older adults' risk of falling and breaking a bone. Falls prevention programmes that include muscle strength and balance exercise improves physical function and helps to prevent falls and broken bones in older adults. However, many older adults stop doing exercise and become less physically active after falls prevention programmes end. Gains in balance and muscle strength are lost and falls risk increase if people don't keep exercising. More people are reaching older ages and becoming less active. Therefore, this problem will worsen unless healthcare practices become better at preventing falls and broken bones in older adults.\n\nThe research ambition is to create a technology supported home exercise programme that encourages older adults to keep exercising after falls prevention programmes end. This will help to prevent future falls and broken bones which will allow more older adults to continue living independently. The home exercise programme will benefit older adults everyday lives by helping them to maintain good physical health and improve their ability to perform daily tasks without the fear of falling.\n\nOlder people at risk of falls, clinicians, and public members will be invited to form a research advisory group. The group will work with the research team to create the home exercise programme and research plan and advise how best to communicate the research to the public. Diversity within the research advisory group will be important to help shape the research to meet the diverse views and needs of the many different people affected by falls and broken bones. We will target the research to help older adults with the greatest health needs. Older adults living in deprived neighbourhoods have the greatest risk of falling and dying following a broken bone. The home exercise programme will be researched in older adults attending falls prevention programmes in the most deprived regions of England. This will help us to explore whether the programme could encourage the continuation of exercise in older adults who need it most.",[28],[63,64,65,66,67,68,69],"Falls Prevention","Ageing Health","Physical activity","Exercise Maintenance","Behaviour Change","Digital health","Older Adults","2024-06-03",{"date":72,"type":37},"2024-06-07",{"date":74,"type":21},"2024-06-20",{"date":76,"type":21},"2026-05-19",{"name":78,"class":44},"Northumbria University"]