[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"falls-accidents-in-old-age\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:falls-accidents-in-old-age":29},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,5,0,[8,48,72,96,124],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":4,"eligibilityCriteria":15,"healthyVolunteers":11,"sex":16,"minAge":17,"maxAge":4,"enrollmentInfo":18,"targetDuration":4,"studyType":21,"phases":22,"briefSummary":24,"conditions":25,"keywords":30,"overallStatus":35,"whyStopped":4,"lastUpdateSubmitDate":36,"lastUpdatePostDateStruct":37,"startDateStruct":40,"completionDateStruct":42,"leadSponsor":44,"locationsCount":47},"100632333","phase-2-effect-of-testosterone-on-elderly-frail-men-with-testosterone-deficiency-100632333",false,"NCT07512323","Effect of Testosterone on Elderly Frail Men With Testosterone Deficiency","Effect of Testosterone on Elderly Frail Men With Testosterone Deficiency - a Double-blinded, Randomized and Placebo-controlled Intervention Study","Inclusion Criteria:\n\n* Men aged 70 or over.\n* Living at home in their own home or in sheltered housing.\n* Independent walking function, possibly with a walking aid.\n* Able to perform the chair-stand test a maximum of 8 times in 30 seconds or Timed Up and Go (TUG) of at least 30 seconds.\n* There must be at least 3 symptoms of frailty or objective findings.\n* Serum testosterone \\\u003C 10 nmol\u002FL as an average of 2 independent measurements at the Center for Growth and Reproduction, Rigshospitalet.\n\nExclusion Criteria:\n\n* Known or previous prostate cancer.\n* Abnormally elevated serum PSA (PSA = prostate-specific antigen) corresponding to PSA \\> 5 ng\u002Fml or PSA \\> 0.15 ng\u002Fml\u002Fcc (relative to prostate size in cubic centimeters (cc)).\n* Hemochromatosis.\n* Heart diseases in the form of: Peri-, myo-, or endocarditis, angina pectoris, severe heart failure (NYHA class III and IV), severe hypertension (systolic BP \\> 180 or diastolic BP \\> 105 mmHg after possible antihypertensive treatment). - Resting dyspnea.\n* Liver (ASAT \\> 2 x upper normal limit) or renal insufficiency (serum creatinine \\> 200 micromol\u002Fl).\n* Severe intractable epilepsy or migraine.\n* Insulin treatment.\n* Previous or current bisphosphonate, fluoride, HRT, SERM, strontium, teriparatide, or more than 3 weeks of prednisolone treatment.\n* Joint disease with acute inflammation.\n* Active cancer disease, in chemo- or radiotherapy.\n* Bone metabolic disease except for age-related osteoporosis.\n* Autoimmune diseases, chronic systemic diseases (cirrhosis, AIDS, chronic renal failure).\n* Primary testosterone deficiency in the form of testicular dysgenesis, Klinefelter syndrome (47,XXY), 46,XX males, LH resistance, Y chromosome deletions, other sex chromosome abnormalities.\n* Significant abuse, mental illness, dementia, physical handicaps with inability to complete the intervention or tests, or to give informed consent.\n* Contraindications for testosterone undecanoate are thus included in exclusion criteria, such as the presence of liver tumors, breast carcinoma, and prostate cancer, for which trial participants will be examined before the start of the trial.","MALE","70 Years",{"count":19,"type":20},96,"ESTIMATED","INTERVENTIONAL",[23],"PHASE2","The purpose of this study is to increase the functional level of the elderly to thereby reduce fall risk, improve motor skills, and increase psychological well-being, as well as to assess whether the restoration of a normal testosterone level contributes to a faster recovery. The effect of testosterone is investigated as measured by physical and mental functional capacity, including cognition, in hypogonadal elderly men with a significant loss of function. The study is aimed at participants who are too weak to participate in the progressive strength training.",[26,27,28,29],"Frail Elderly Patients","Hypogonadal Males","Testosterone Replacement Therapy","Falls (Accidents) in Old Age",[31,32,33,34],"hypogonadism","frailty","falls","testosterone replacement therapy","NOT_YET_RECRUITING","2026-04-29",{"date":38,"type":39},"2026-05-06","ACTUAL",{"date":41,"type":20},"2026-08-01",{"date":43,"type":20},"2030-09-30",{"name":45,"class":46},"Rune Skovgaard Rasmussen","OTHER",1,{"id":49,"slug":50,"hasResults":11,"nctId":51,"briefTitle":52,"officialTitle":52,"acronym":4,"eligibilityCriteria":53,"healthyVolunteers":11,"sex":54,"minAge":55,"maxAge":4,"enrollmentInfo":56,"targetDuration":4,"studyType":58,"phases":4,"briefSummary":59,"conditions":60,"keywords":4,"overallStatus":62,"whyStopped":4,"lastUpdateSubmitDate":63,"lastUpdatePostDateStruct":64,"startDateStruct":66,"completionDateStruct":68,"leadSponsor":70,"locationsCount":47},"100601598","association-between-intake-of-psychotropic-medications-and-risk-of-falls-in-older-adults-100601598","NCT07112573","Association Between Intake of Psychotropic Medications and Risk of Falls in Older Adults","Inclusion Criteria:\n\n* patients (males and females) aged ≥ 60 years old patients who accept to participate in the study\n\nExclusion Criteria:\n\n* Patients with malignancy Bedridden patients","ALL","60 Years",{"count":57,"type":20},398,"OBSERVATIONAL","The aim of the study is to assess the association between intake of psychotropic medications and increased risk of falls in older adults discharged from Ain Shams University Geriatric Hospital as a primary outcome and incident fractures that may occur as a secondary outcome of such fall.",[29,61],"Psychotropic Drugs","RECRUITING","2026-03-14",{"date":65,"type":39},"2026-03-17",{"date":67,"type":39},"2025-07-01",{"date":69,"type":20},"2026-06",{"name":71,"class":46},"Ain Shams University",{"id":73,"slug":74,"hasResults":11,"nctId":75,"briefTitle":76,"officialTitle":76,"acronym":4,"eligibilityCriteria":77,"healthyVolunteers":78,"sex":54,"minAge":79,"maxAge":4,"enrollmentInfo":80,"targetDuration":4,"studyType":58,"phases":4,"briefSummary":82,"conditions":83,"keywords":4,"overallStatus":62,"whyStopped":4,"lastUpdateSubmitDate":87,"lastUpdatePostDateStruct":88,"startDateStruct":90,"completionDateStruct":92,"leadSponsor":94,"locationsCount":47},"100590006","validating-a-multifactorial-algorithm-to-predict-fall-risk-in-community-dwelling-older-persons-aged-65-years-or-older-100590006","NCT06961799","Validating a Multifactorial Algorithm to Predict Fall Risk in Community Dwelling Older Persons Aged 65 Years or Older","Inclusion Criteria:\n\n* 65years or older\n* community dwellers\n* absence of surgery or exacerbation of symptoms in the last 6 months\n* ability to stand and walk independently (alone), possibly with an walking aid.\n\nExclusion Criteria:\n\n* \\\u003C65 years of age\n* surgery within the previous 6 months affecting gait and mobility\n* exacerbation of symptoms coming from a diagnosed disease\n* older adults with insufficient (language) comprehension to complete the tests and questionnaires",true,"65 Years",{"count":81,"type":20},228,"Falls in older adults have an annual incidence between 23 and 34% for persons of 65 years and older. The lack of transfer of promising research results on falls prevention to daily practice may have several explanations. One of the first concerns for that matter may be a valid and sensitive selection of the persons at risk who are eligible for fall prevention interventions\n\nGoals of the prospective obeservational study:\n\n1. To validate a new, comprehensive, multifactorial screeningsintrument to predict the risk on falls in community dwelling, Belgian, older adults (\\>65years or older).\n2. To optimize the new, comprehensive, multifactorial screeningsintrument and to specify correct cut off scores\n\nResearchers will compare the data of the accuracy of new algorithm with the current Belgian policy.\n\nParticipants will participate in a one-time testing moment, where they will be asked some questions about general characteristics and medical history, followed by two questionnaire and seven physical tests . Based on this data, their fall risk will be assessed. In the year that follows, the older person's fall behavior will be monitored with a monthly falls calender. Participant will be asked to fill out these calenders everyday ('Did you fall today?' YES\u002FNO) and send them at the end of each month to the researchers, digitally or postal.",[84,85,86,29],"Aged 65 Years or Older","Community Dwelling Older Adults","Falls Risk","2025-05-05",{"date":89,"type":39},"2025-05-08",{"date":91,"type":39},"2025-03-20",{"date":93,"type":20},"2026-12",{"name":95,"class":46},"University Ghent",{"id":97,"slug":98,"hasResults":11,"nctId":99,"briefTitle":100,"officialTitle":100,"acronym":101,"eligibilityCriteria":102,"healthyVolunteers":78,"sex":54,"minAge":55,"maxAge":4,"enrollmentInfo":103,"targetDuration":4,"studyType":21,"phases":105,"briefSummary":107,"conditions":108,"keywords":110,"overallStatus":35,"whyStopped":4,"lastUpdateSubmitDate":116,"lastUpdatePostDateStruct":117,"startDateStruct":118,"completionDateStruct":120,"leadSponsor":122,"locationsCount":47},"100590007","validation-of-the-self-assessment-for-falls-in-the-elderly-safe-questionnaire-to-assess-the-risk-of-falls-in-people-aged-60-or-over-100590007","NCT06961812","Validation of the Self-Assessment for Falls in the Elderly (SAFE) Questionnaire to Assess the Risk of Falls in People Aged 60 or Over.","SAFE","Inclusion Criteria:\n\n* People aged 60 or over, judged by the investigator to be in stable clinical condition as regards walking and balance for at least one month,\n* Able to perform the necessary physical assessments\n\nExclusion Criteria:\n\n* Unable, according to the investigator, to answer a self-questionnaire,\n* Patient's refusal to take part in the study\n* Absence of a caregiver if the participant is unable to answer the questionnaire alone\n* Unable to understand the information note\n* Opposition of the proxy or legal guardian if the participant is under legal protection (guardianship, curatorship, safeguard of justice)\n* Subject deprived of liberty (art. L. 1121-6) (by judicial or administrative decision, or forced hospitalization)\n* Not affiliated to a French social security scheme or beneficiary of such a scheme (L1121-8-1)\n* Participation in other research involving a period of exclusion still in progress (Article L1121-12)",{"count":104,"type":20},300,[106],"NA","This single-centre, cross-sectional diagnostic study will determine whether the new self-completed Self-Assessment for Falls in the Elderly (SAFE) questionnaire can classify fall-risk level (low, moderate, high) in adults ≥ 60 years as accurately as the current clinician-administered international algorithm that mixes yes\u002Fno questions with physical tests; to do so, about 300 participants will (1) sign consent, (2) answer the 5-minute SAFE, and (3) undergo guideline assessment and tests by a clinician in the same visit, after which researchers will compare SAFE and clinician results for sensitivity, specificity, and predictive values, examine agreement and correlations, and give immediate risk-based prevention advice:\n\n* Eligibility: men or women ≥ 60 y, stable walking\u002Fbalance ≥ 1 month, able to read French and perform brief tests; legal guardianship or refusal excludes.\n* Participant tasks: complete SAFE; perform Timed Up-and-Go, 4 m gait speed, Five-Times-Sit-to-Stand and Short Physical Performance Battery (SPPB) under supervision\n* Benefits\u002FRisks: instant personalised fall-risk feedback; SAFE is risk-free and physical tests carry only minimal supervised exertion.\n\nFalls are a leading cause of injury and death in older adults, and current assessments require trained staff; if SAFE proves equivalent, it could enable large-scale, low-cost self-screening and support future digital monitoring tools for fall prevention.",[109,29],"Fall Prevention",[111,112,113,114,115],"Falls","Functional Assessment","Predictive Value of Tests","Aging","Fallers Aged 60 Years and Older","2025-04-29",{"date":89,"type":39},{"date":119,"type":20},"2025-05-02",{"date":121,"type":20},"2026-05-02",{"name":123,"class":46},"University Hospital, Montpellier",{"id":125,"slug":126,"hasResults":11,"nctId":127,"briefTitle":128,"officialTitle":128,"acronym":4,"eligibilityCriteria":129,"healthyVolunteers":78,"sex":54,"minAge":55,"maxAge":130,"enrollmentInfo":131,"targetDuration":4,"studyType":21,"phases":133,"briefSummary":134,"conditions":135,"keywords":4,"overallStatus":35,"whyStopped":4,"lastUpdateSubmitDate":138,"lastUpdatePostDateStruct":139,"startDateStruct":141,"completionDateStruct":143,"leadSponsor":145,"locationsCount":147},"100558009","does-participation-in-a-fall-preparedness-program-improve-fall-efficacy-among-older-adults-100558009","NCT06545539","Does Participation in a Fall Preparedness Program Improve Fall Efficacy Among Older Adults","Inclusion Criteria:\n\n* Adults age 60 and up\n* able to participate in exercise program\n\nExclusion criteria:\n\n* Adults age \\\u003C60 year old\n* severe medical condition that prohibits the ability to participate in an exercise program\n* 6CIT score that indicates severely impaired cognition.\n\nSevere medical conditions will be screed by a licensed Physical Therapist. Under the Ohio Practice Act, physical therapists in Ohio are permitted to differently diagnosis. The class participants will be community-dwelling older adults who are less likely to come to participate in an exercise class if they have any severe medical conditions.\n\nAny participants with mild cognitive impairment who are not excluded from the study will be offered simplified instructions by the licensed physical therapist performing the assessments. They will also be offered increased verbal, visual, and tactile cues as needed throughout the program to ensure understanding.","105 Years",{"count":132,"type":20},30,[106],"The purpose of this study is to determine if a fall preparedness program can reduce the fear of falling in older adults and subsequently improve their function and reduce falls with injury.\n\nParticipants will perform baseline measures 4 weeks before intervention and again at the start of intervention. They will perform a 12-week intervention and then complete outcome measures again at the conclusion of the program.",[136,137,29],"Fall Injury","Fall","2024-08-09",{"date":140,"type":39},"2024-08-13",{"date":142,"type":20},"2024-08-01",{"date":144,"type":20},"2026-12-31",{"name":146,"class":46},"Youngstown State University",2]