[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"falls-prevention\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:falls-prevention":27},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,5,0,[8,48,74,129,164],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":4,"eligibilityCriteria":15,"healthyVolunteers":11,"sex":16,"minAge":17,"maxAge":4,"enrollmentInfo":18,"targetDuration":4,"studyType":21,"phases":22,"briefSummary":24,"conditions":25,"keywords":29,"overallStatus":35,"whyStopped":4,"lastUpdateSubmitDate":36,"lastUpdatePostDateStruct":37,"startDateStruct":40,"completionDateStruct":42,"leadSponsor":44,"locationsCount":47},"100637074","home-based-exercise-programs-for-fall-prevention-in-parkinson-disease-100637074",false,"NCT07590700","Home-Based Exercise Programs for Fall Prevention in Parkinson Disease","Effectiveness of Fall-Preventive Home Exercise Programs in Patients With Parkinson Disease: A Randomized Controlled Trial","Inclusion Criteria:\n\n* Diagnosis of Parkinson disease confirmed by a neurologist\n* Hoehn and Yahr stage 3 or 4 Parkinson disease\n* Diagnosis of Parkinson disease for at least 5 years\n* Willingness to participate in the study and provide written informed consent\n* Ability to walk independently or with minimal assistance\n* Mini-Mental State Examination score \\>24\n\nExclusion Criteria:\n\n* Balance or gait impairment due to causes other than Parkinson disease, such as severe orthopedic problems or another neurological disease\n* Red flags suggestive of Parkinson-plus syndromes, such as symmetric onset, early falls, early-onset dementia, or gaze palsy\n* History of serious fall-related injury or surgery within the last 6 months\n* Any additional health condition that would prevent participation in the exercise program during the study period","ALL","40 Years",{"count":19,"type":20},30,"ESTIMATED","INTERVENTIONAL",[23],"NA","Falls are common in patients with Parkinson disease and may lead to reduced mobility, fear of falling, loss of independence, and injury. Exercise-based rehabilitation programs may help improve balance, gait, and physical performance in this population.\n\nThis randomized controlled trial aims to compare the effectiveness of two home-based exercise programs in patients with Parkinson disease: the Otago Exercise Program and a structured home exercise program. Participants will be randomly assigned to one of two groups. Both groups will receive exercise education and will perform their assigned home exercise program for 6 weeks.\n\nParticipants will be evaluated at baseline, at week 3, and at the end of week 6. The study will assess fall-related outcomes, freezing of gait, functional mobility, gait parameters, postural control, and physical performance. The results may help determine which home-based exercise approach is more effective for reducing fall risk and improving functional outcomes in patients with Parkinson disease.",[26,27,28],"PARKINSON DISEASE (Disorder)","Falls Prevention","Exercise",[30,31,32,33,34],"parkinson disease","fall prevention","Otago","Home-based","Execise","RECRUITING","2026-05-15",{"date":38,"type":39},"2026-05-19","ACTUAL",{"date":41,"type":39},"2026-02-08",{"date":43,"type":20},"2026-08",{"name":45,"class":46},"Uludag University","OTHER",1,{"id":49,"slug":50,"hasResults":11,"nctId":51,"briefTitle":52,"officialTitle":52,"acronym":53,"eligibilityCriteria":54,"healthyVolunteers":11,"sex":16,"minAge":55,"maxAge":4,"enrollmentInfo":56,"targetDuration":4,"studyType":21,"phases":58,"briefSummary":59,"conditions":60,"keywords":61,"overallStatus":35,"whyStopped":4,"lastUpdateSubmitDate":65,"lastUpdatePostDateStruct":66,"startDateStruct":68,"completionDateStruct":70,"leadSponsor":72,"locationsCount":47},"100621306","walk-on-national-council-on-aging-innovation-lab-100621306","NCT07368907","Walk On! National Council on Aging Innovation Lab","Walk On! NCOA","Program Older Adult Participants: Inclusion Criteria:\n\n* Age greater than or equal to 60 years\n* Able to provide own transportation to the program each week\n* No planned extended travel or time away during the 12 week program period\n* English speaking with intact verbal and written communication skills\n* Free of current fracture\n* Able to ambulate independently, with or without an assistive device (i.e., cane or walker)\n\nProgram Participants: Exclusion Criteria:\n\n* Serious or unstable medical or psychiatric condition that would prevent participation in research study\n* Lack of decision-making capacity\n* Participated in an evidence-based falls prevention program within the past 12 months\n\nCommunity-Based Organizations (CBOs): Inclusion Criteria:\n\n* Age greater than or equal to 18 years\n* English speaking\n\nCommunity-Based Organizations (CBOs): Exclusion Criteria:\n\n* Not interested in offering a Walk On! program\n* Unwilling and\u002For unable to participate in implementation activities","18 Years",{"count":57,"type":20},192,[23],"This is a multi-site, one-arm type-2 hybrid-effectiveness implementation trial. The goal of this clinical trial is to learn if the Walk On! program helps prevent falls in older adults who have trouble moving around or feel socially isolated. Researchers want to know:\n\n1. What are the best ways for organizations to offer the Walk On! program and keep it running for older adults in their community?\n2. Does Walk On! help prevent falls in older adults?\n\nOlder Adult Participants will:\n\n1. Join group walking sessions led by a trained facilitator\n2. Meet twice a week for 12 weeks (24 sessions)\n3. Take part in simple tests before and after the program to see if there are any changes in older adults' function, confidence in not falling, or loneliness.",[27],[62,63,64],"Mobility Limitation","Implementation Science","Community-based","2026-04-23",{"date":67,"type":39},"2026-04-29",{"date":69,"type":39},"2026-04-06",{"date":71,"type":20},"2027-05",{"name":73,"class":46},"Wake Forest University Health Sciences",{"id":75,"slug":76,"hasResults":11,"nctId":77,"briefTitle":78,"officialTitle":79,"acronym":4,"eligibilityCriteria":80,"healthyVolunteers":11,"sex":16,"minAge":55,"maxAge":81,"enrollmentInfo":82,"targetDuration":4,"studyType":21,"phases":84,"briefSummary":85,"conditions":86,"keywords":96,"overallStatus":121,"whyStopped":4,"lastUpdateSubmitDate":122,"lastUpdatePostDateStruct":123,"startDateStruct":125,"completionDateStruct":126,"leadSponsor":127,"locationsCount":47},"100612195","development-and-efficacy-of-a-novel-cost-effective-gait-training-device-utilized-at-home-for-stroke-survivors-100612195","NCT07250425","Development and Efficacy of a Novel, Cost-Effective Gait Training Device Utilized at Home for Stroke Survivors","Development of a Novel, Cost-Effective Gait Training Device Utilized at Home for the Neurological Patient Population","Inclusion Criteria:\n\n* Age ≥ 18 years.\n* First-ever ischemic or hemorrhagic stroke confirmed by medical record.\n* 3 months to 5 years post-stroke at time of enrollment.\n* Presence of lower-extremity motor impairment limiting walking function.\n* Able to stand for at least 30 minutes with no more than minimal assistance (with or without a device).\n* Medically stable and cleared by a physician to participate in moderate-intensity ambulation exercise.\n* Living in a home environment that can safely accommodate device installation (e.g., adequate space, appropriate flooring, and power access) as determined by the study team.\n* Able to understand study procedures and provide informed consent (or have a legally authorized representative), with sufficient cognitive and communication skills to follow simple instructions.\n* If assistance is required for transfers or device set-up, availability of a caregiver or assistant willing to participate in training and device use.\n\nExclusion Criteria:\n\n* Unstable cardiovascular, respiratory, or other medical conditions that contraindicate moderate- to high-intensity walking exercise (e.g., unstable angina, decompensated heart failure, uncontrolled arrhythmias).\n* Severe musculoskeletal or orthopedic conditions limiting safe participation in supported stepping (e.g., unstable fractures, severe contractures preventing positioning in the device).\n* Severe spasticity or movement disorders that would preclude safe use of the device, based on investigator judgment.\n* Severe cognitive impairment, aphasia, or behavioral disturbance that would prevent informed consent or safe participation.\n* Progressive neurological conditions (e.g., progressive neurodegenerative disease) expected to significantly worsen over the 12-week study period.\n* Current participation in another interventional trial targeting gait or lower-extremity function.\n* Any other condition that, in the opinion of the investigators, would make participation unsafe or interfere with study adherence or outcome interpretation.","75 Years",{"count":83,"type":20},20,[23],"This pilot, parallel-group randomized controlled trial will evaluate the feasibility, safety, usability, and preliminary efficacy of the Rise\\&Walk InHome (RWH), a novel robotic gait training device designed for home use after stroke. Twenty adults with lower-extremity motor impairment following a first-ever stroke (3 months to 5 years post-event) will be randomized 1:1 to either (1) RWH-assisted home walking plus usual care or (2) usual care alone for 12 weeks. Participants in the intervention group will receive an in-home RWH device, complete a structured device training program, and be instructed to perform 30-minute RWH walking sessions four times per week (48 sessions total). All participants will undergo standardized outcome assessments at baseline, weeks 4, 8, and 12, including the 6-Minute Walk Test (primary outcome), 10-Meter Walk Test, daily step count via wearable activity tracker, and health-related quality of life (SF-36). Additional feasibility and usability outcomes include device use and adherence, patient satisfaction and motivation, ease of use, perceived exertion, and adverse events. Findings will inform the feasibility of in-home deployment of the RWH device and provide preliminary effect-size estimates to guide the design of a larger efficacy trial.",[87,88,89,90,91,92,93,94,27,95,62],"Stroke","Neurological Diseases or Conditions","Hemiparesis;Poststroke\u002FCVA","Gait Disorders, Neurologic","Post Stroke Fatigue","Motor Recovery","Walking Difficulty","Balance Impairment","Hemiparesis",[97,98,99,100,101,102,103,104,105,106,107,108,109,110,111,112,113,114,115,116,117,118,119,120],"in-home rehabilitation","Robotic-Assisted Gait Training","gait training device","stroke recovery","functional mobility","rehabilitation technology","remote monitoring","rehabilitation robotics","Fitbit Step Tracking","Self-Directed Gait Training","high-intensity gait training","Neurorehabilitation Research","Lower Limb Rehabilitation","Motor Function Recovery","Physical Therapy","Walking Endurance","task specific walking practice","neurological recovery","stroke rehabilitation","home exercise program","Rise&Walk InHome","daily step count","6-minute walk test","10-meter walk test","NOT_YET_RECRUITING","2026-03-06",{"date":124,"type":39},"2026-03-09",{"date":43,"type":20},{"date":43,"type":20},{"name":128,"class":46},"Healing Innovations",{"id":130,"slug":131,"hasResults":11,"nctId":132,"briefTitle":133,"officialTitle":134,"acronym":135,"eligibilityCriteria":136,"healthyVolunteers":11,"sex":16,"minAge":137,"maxAge":138,"enrollmentInfo":139,"targetDuration":4,"studyType":21,"phases":141,"briefSummary":142,"conditions":143,"keywords":145,"overallStatus":35,"whyStopped":4,"lastUpdateSubmitDate":155,"lastUpdatePostDateStruct":156,"startDateStruct":158,"completionDateStruct":160,"leadSponsor":162,"locationsCount":47},"100563088","analysis-of-the-loss-of-muscle-force-power-and-motor-control-to-predict-the-risk-of-falls-in-patients-with-knee-oa-100563088","NCT06611618","Analysis of the Loss of Muscle Force, Power and Motor Control to Predict the Risk of Falls in Patients With Knee OA","Analisi Della Perdita di Forza e Potenza Muscolare e Del Degrado Del Controllo Motorio Per la Predizione Delle Cadute in Una Popolazione Affetta da Artrosi di Ginocchio","PowerAGING","Inclusion Criteria:\n\n* Age between 65 and 80 years\n* Kellgren score II e III\n* No history of falls in the last 12 months\n\nExclusion Criteria:\n\n* Any musculoskeletal, neurological, rheumatic or tumoral diseases\n* Dementia\n* Diabetes\n* Inguinal or abdominal hernia\n* Severe Hypertension (Level 3)\n* Severe Cardio-pulmonary insufficiency\n* Diagnosis of Osteonecrosis in the lower limb joints\n* Pathologies or physical conditions incompatible with the use of magnetic resonance imaging and electrostimulation (i.e., active and passive implanted biomedical devices, epilepsy, severe venous insufficiency in the lower limbs)\n* Previous interventions or traumas to the joints of the lower limb","65 Years","80 Years",{"count":140,"type":20},50,[23],"The twofold goal of this study is to understand the link between muscle power, muscle strength, and muscle control degradation with the risk of falling, and to develop a framework for the comprehensive and quantitative assessment of muscle power (and strength) in an elderly population of patients with knee osteoarthritis, who are at higher risk of falling. The main question it aims to answer is:\n\n● Are muscle power and motor control degradation better predictors of falls than muscle strength in the aging population?\n\nParticipants will undergo:\n\n* Muscle force assessment on a dynamometer\n* Muscle power assessment on a dynamometer and on isntrumented stairs\n* Home-based mobility monitoring\n* Full lower limb MRI acquisition\n* Gait assessment",[144,27],"Knee Osteoarthritis (Knee OA)",[146,147,148,149,150,151,152,153,154],"Falls prevention","Knee osteoarthritis","Muscle power","Muscle force","Motor control degradation","digital twins","IMU","mobility monitoring","MRI","2026-02-24",{"date":157,"type":39},"2026-02-27",{"date":159,"type":39},"2025-01-30",{"date":161,"type":20},"2026-12-12",{"name":163,"class":46},"Istituto Ortopedico Rizzoli",{"id":165,"slug":166,"hasResults":11,"nctId":167,"briefTitle":168,"officialTitle":169,"acronym":170,"eligibilityCriteria":171,"healthyVolunteers":11,"sex":16,"minAge":137,"maxAge":4,"enrollmentInfo":172,"targetDuration":4,"studyType":21,"phases":174,"briefSummary":175,"conditions":176,"keywords":4,"overallStatus":35,"whyStopped":4,"lastUpdateSubmitDate":182,"lastUpdatePostDateStruct":183,"startDateStruct":185,"completionDateStruct":187,"leadSponsor":189,"locationsCount":47},"100566001","identify-the-most-effective-rehabilitation-method-between-a-treatment-with-a-sensorized-treadmill-walker-view-and-a-treatment-with-conventional-group-therapy-in-balance-disorders-and-the-use-of-artificial-intelligence-to-identify-predictive-indices-to-prevent-falls-and-diagnose-promptly-the-risk-100566001","NCT06649500","Identify the Most Effective Rehabilitation Method Between a Treatment with a Sensorized Treadmill (Walker View) and a Treatment with Conventional Group Therapy in Balance Disorders and the Use of Artificial Intelligence to Identify Predictive Indices to Prevent Falls and Diagnose Promptly the Risk","Comparison Between Treatment with Sensorized Treadmill and Conventional Therapy in Balance Disorders and Use of Artificial Intelligence in Identifying Predictive and Prognostic Indices of the Risk of Falling in Balance Disorders in Adult-elderly Subjects","UAI","Inclusion Criteria:\n\n* Age ≥ 65 years\n* Consent to participate in the study\n* Positive history of balance disorders\n* Absence of cognitive deficits (MMSE ≥ 24)\n* Tinetti \\< 25\n\nExclusion Criteria:\n\n* Clinical pictures associated with musculoskeletal, cardiovascular, cerebrovascular, neuro-psychic problems and post-surgical outcomes that make the planned evaluation tests unfeasible.\n* Inability to carry out a walking test.\n* History of more than one fall in the last six months.\n* Subjects who have not expressed informed consent to participate in the study.",{"count":173,"type":20},108,[23],"Falls in the elderly are one of the main sources of disability and hospitalization, with a significant impact on quality of life and social and healthcare costs. Falls represent a significant health concern for people over 60 years old. Numerous studies have shown that falls cause serious health consequences. Around 30% of people over the age of 60 experience a fall during the year.\n\nAccording to the impact falls have, the investigators decided to analyze the effectiveness of training on a Walker View sensorized treadmill, with the possibility of exercises for coordination and balance, compared to training with a conventional group therapy, in order to understand the best training to reduce the risk of falling and observe the possible improvements in daily life activities.\n\nSo the study aims to identify the most effective rehabilitation method between a treatment with a sensorized treadmill (Walker View) and a conventional group therapy in balance disorders.\n\nThe study also aims to identify predictive indices, with the use of Artificial Intelligence, that can contribute to the prevention and diagnosis of balance disorders in a short time and prevent falls in the elderly.",[177,178,179,27,180,181],"Balance Disorders","Rehabilitation","Falls","Artificial Intelligence (AI)","Elderly (people Aged 65 or More)","2025-03-17",{"date":184,"type":39},"2025-03-19",{"date":186,"type":39},"2024-12-04",{"date":188,"type":20},"2026-06",{"name":190,"class":46},"Fondazione Policlinico Universitario Campus Bio-Medico"]