[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"family-functioning\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:family-functioning":31},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,4,0,[8,52,82,112],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":15,"eligibilityCriteria":16,"healthyVolunteers":17,"sex":18,"minAge":19,"maxAge":20,"enrollmentInfo":21,"targetDuration":4,"studyType":24,"phases":25,"briefSummary":27,"conditions":28,"keywords":33,"overallStatus":39,"whyStopped":4,"lastUpdateSubmitDate":40,"lastUpdatePostDateStruct":41,"startDateStruct":44,"completionDateStruct":46,"leadSponsor":48,"locationsCount":51},"100611437","randomized-controlled-trial-of-a-family-focused-intervention-for-caregivers-and-young-adolescents-phase-3-of-flourish-100611437",false,"NCT07240571","Randomized Controlled Trial of a Family-focused Intervention for Caregivers and Young Adolescents (Phase 3 of FLOURISH)","Family-Focused Adolescent & Lifelong Health Promotion: Prevention of Adolescent Mental Health Problems in Eastern Europe","FLOURISH","Inclusion Criteria:\n\n* For Caregivers:\n\nMust be 18 years or older at baseline assessment\n\nMust be the primary caregiver of an adolescent aged 10-14 who has resided in the same household for at least four nights a week in the past month\n\nMust be able to speak at least one of the local languages in which the program will be offered (e.g., Macedonian, Romanian, Russian, Ukrainian or Albanian)\n\nMust agree to participate in the program and provide informed consent for both themselves and their adolescent\n\nFor Adolescents:\n\nMust be aged 10-14 at the baseline assessment\n\nMust provide assent to participate in the study\n\nMust have caregiver consent to participate.\n\nExclusion Criteria:\n\n* No formal exclusion criteria have been established for the FLOURISH project. However, during the study introduction, the research team will guide participants through a consent form that asks whether they are currently experiencing acute distress or a mental or physical health condition that could interfere with participation. The decision to participate will be made by the individual. If a potential participant indicates they are unable to take part due to acute health issues, the research team will provide appropriate referrals to other services.",true,"ALL","10 Years","14 Years",{"count":22,"type":23},1280,"ESTIMATED","INTERVENTIONAL",[26],"NA","The aim of this study is to conduct a multi-country randomized waitlist controlled trial to evaluate the effectiveness, cost-effectiveness, and scalability of the optimized Parenting for Lifelong Health (PLH) for Parents and Teens program in Moldova and North Macedonia. In Phase 2 of the FLOURISH project, a factorial trial tested multiple intervention components and identified the optimized intervention package. In Phase 3, this trial will assess the implementation, outcomes, and economic impact of the optimized PLH program delivered to adolescents aged 10-14 and their caregivers. ALTERNATIVA will deliver the program in North Macedonia and the Health for Youth Association in the Republic of Moldova.",[29,30,31,32],"Adolescent - Emotional Problem","Parent Child Relationship","Family Functioning","Well-Being, Psychological",[34,35,36,37,38],"Multiphase Optimization Strategy (MOST)","Family-based intervention","Adolescents","Mental health","Randomized trial","RECRUITING","2026-05-28",{"date":42,"type":43},"2026-06-02","ACTUAL",{"date":45,"type":43},"2025-10-24",{"date":47,"type":23},"2026-11-30",{"name":49,"class":50},"University of Klagenfurt","OTHER",2,{"id":53,"slug":54,"hasResults":11,"nctId":55,"briefTitle":56,"officialTitle":57,"acronym":4,"eligibilityCriteria":58,"healthyVolunteers":17,"sex":18,"minAge":59,"maxAge":20,"enrollmentInfo":60,"targetDuration":4,"studyType":24,"phases":62,"briefSummary":63,"conditions":64,"keywords":66,"overallStatus":39,"whyStopped":4,"lastUpdateSubmitDate":72,"lastUpdatePostDateStruct":73,"startDateStruct":75,"completionDateStruct":77,"leadSponsor":79,"locationsCount":81},"100579187","the-thrive-study-teaching-healthy-regulation-in-individuals--vulnerable-environments-100579187","NCT06821035","The THRIVE Study: Teaching Healthy Regulation in Individuals & Vulnerable Environments","Teaching Youth & Families Self-Regulation Skills to Disrupt the Impact of Adverse Childhood Experiences: Preventing Substance Use in Adversity- Impacted Youth","Inclusion Criteria:\n\n* Youth ages 11-14 years who score in the High-Risk category (i.e., 4 or more ACEs) on the ACEs and Toxic Stress Risk Assessment Algorithm\n* Has access to a smartphone and is willing to download applicable apps (95% of all adolescents have access to a smartphone)\n* Youth who are able to speak and read in English\n* Has a parent\u002Fguardian\u002Fprimary caregiver (18 years or older) who is English- or Spanish-speaking and willing to participate in the intervention.\n\nExclusion Criteria:\n\n* Youth who cannot speak and read in English\n* Youth who report any alcohol or cannabis use within the last 14 days\n* Youth currently enrolled in another family-based intervention (i.e., family therapy)\n* Youth in acute distress who are in immediate need of care (e.g., imminent risk of harm to self or others, active psychosis)\n* Youth who report their caregivers' home environment is unsafe to return to, have been deemed unsafe, or require supervised visits by the Department of Children and Family Services (DCFS)\n* Youth whose parent\u002Fguardian\u002Fprimary caregiver declines participation will be referred to other programs in their community.\n* Due to drug experimentation being common in adolescence, our interest in preventing the early initiation of regular use of alcohol and cannabis use, and youth who regularly use substances requiring a different intervention, we will enroll youth who initially report recent cannabis use but later report no use within the last two weeks and have a confirmatory negative urine drug screening.","11 Years",{"count":61,"type":23},210,[26],"The goal of this 2-arm randomized control trial is to determine the impact of a community health worker delivered coaching intervention, GRIT, on preventing the early initiation of regular use of alcohol and cannabis among adversity-impacted adolescents ages 11-14 who do not regularly use alcohol or cannabis at baseline. The specific aims include:\n\n* Aim 1. Examine the effect of GRIT on preventing the early initiation of regular alcohol and cannabis use over time.\n* Aim 2. Examine the role of youth and caregiver self-regulation in mediating the effect of GRIT on adolescent rates of alcohol and cannabis use.\n\nResearchers will compare participants who are randomized to the GRIT intervention to an active control group, receiving a Digital Citizenship Curriculum, to see if those who participate in GRIT experience greater improvements in self-regulation and lower cardiometabolic risks.\n\nParticipants will:\n\n* Be randomized to either receive the GRIT intervention (experimental group) or the Digital Citizenship Curriculum (active control group)\n* Complete 3 in-person visits at baseline, post-intervention, and 12-month post intervention\n* Complete HRV assessments using emWave Pro Plus and survey assessments on REDCap during in-person visits.\n* Participate in six 60-minute sessions conducted over 8 weeks via Zoom with an assigned community-health worker\n* Be invited to complete a booster session at 6-months post-intervention\n* Complete online measures at baseline, post-intervention, 6-month, and 12-month post-intervention",[65,31],"Adverse Childhood Experiences",[67,68,69,70,71],"Alcohol and Substance Use Prevention","Youth Risk Behaviors","Traumatized Youth","stress management","adolescent","2026-03-16",{"date":74,"type":43},"2026-03-18",{"date":76,"type":43},"2025-04-17",{"date":78,"type":23},"2028-08-31",{"name":80,"class":50},"University of California, Irvine",1,{"id":83,"slug":84,"hasResults":11,"nctId":85,"briefTitle":86,"officialTitle":86,"acronym":4,"eligibilityCriteria":87,"healthyVolunteers":11,"sex":18,"minAge":4,"maxAge":4,"enrollmentInfo":88,"targetDuration":4,"studyType":24,"phases":90,"briefSummary":91,"conditions":92,"keywords":95,"overallStatus":39,"whyStopped":4,"lastUpdateSubmitDate":103,"lastUpdatePostDateStruct":104,"startDateStruct":106,"completionDateStruct":108,"leadSponsor":110,"locationsCount":81},"100601152","evaluation-of-the-family-intervention-program-pif-100601152","NCT07106775","Evaluation of the Family Intervention Program (PIF)","Inclusion Criteria:\n\n* Being a psychosocial at-risk family with at least one child under 18 years of age\n* Living in the territory that corresponds to that social services center\n\nExclusion Criteria:\n\n* Experience family crisis that prevent for participating in the home intervention\n* Experience mental health issue that prevent for participating in the home intervention\n* High level of psychosolcial risk",{"count":89,"type":23},50,[26],"The goal of this study is to evaluate the effectiveness of home positive parenting programs targeted to families at psychosocial risk carried out in Cantabria (Spain).\n\nThe investigators will collect information before the intervention, and every six months until the family achieves the proposed objectives (with a maximum intervention period of two years). Besides, the investigators will compare these results with information from other families that are not taking part in the program. Depending on the case, the practitioners in charge of the intervention, the main caregivers of the participating families and\u002For the adolescents will provide the information for the study.\n\nThe investigators expect that families participating in the programs will improve their parenting competencies, their family dynamics, and the life quality of their children.",[93,94,31],"Parenting","Children\u002FAdolescent Adjustment",[96,97,98,99,100,101,102],"Positive parenting","Parenting competences","Program evaluation","Family functioning","Parenting practices","Effectiveness","Home program","2025-08-11",{"date":105,"type":43},"2025-08-14",{"date":107,"type":43},"2025-01-15",{"date":109,"type":23},"2026-05",{"name":111,"class":50},"University of Seville",{"id":113,"slug":114,"hasResults":11,"nctId":115,"briefTitle":116,"officialTitle":116,"acronym":117,"eligibilityCriteria":118,"healthyVolunteers":17,"sex":18,"minAge":119,"maxAge":120,"enrollmentInfo":121,"targetDuration":4,"studyType":24,"phases":123,"briefSummary":124,"conditions":125,"keywords":127,"overallStatus":39,"whyStopped":4,"lastUpdateSubmitDate":133,"lastUpdatePostDateStruct":134,"startDateStruct":136,"completionDateStruct":138,"leadSponsor":140,"locationsCount":81},"100523670","all-in-the-family-promoting-family-function-through-physical-activity-100523670","NCT06098716","All in the Family: Promoting Family Function Through Physical Activity","SSHRC-Family","Inclusion Criteria:\n\nParticipants will be at least one parent with at least one child between the ages of 6 and 12 years.\n\nFamilies (parents and\u002For guardians and children) residing in Canada. Children that participate in \\\u003C60 minutes\u002Fday of moderate to vigorous physical activity (MVPA).\n\nExclusion Criteria:\n\nIf child is meeting the current physical activity guidelines \\>=60 minutes a day of moderate to vigorous physical activity per day.\n\nIf the participant does not pass the Physical Activity Readiness Questionnaire (PARQ) If children's age falls outside the 6-12 year range","6 Years","12 Years",{"count":122,"type":23},165,[26],"The goal of this trial is to find out whether adding identity-building and self-regulation training to basic healthy-living education helps families with inactive children (ages 6-12) become more cohesive and physically active. The main question it aims to answer is:\n\nDoes the identity + self-regulation + education program improve family cohesion more than (a) self-regulation + education or (b) education alone?\n\nResearchers will compare three groups-identity+self-regulation+education (ID), self-regulation+education (SR), and education-only (ED)-to see which produces the greatest improvements.\n\nParticipants will:\n\n1. attend three online workshops at baseline plus two booster sessions at 6-week and 3-month with a project coordinator;\n2. complete online questionnaires at baseline, 6-week, 3-month, and 6-month;\n3. take part in an exit interview at 6 months.",[126,31],"Physical Activity",[128,129,31,130,131,132],"Parenting Practices","Exercise","Identity","Self-Regulation;","Parental Support","2025-06-20",{"date":135,"type":43},"2025-06-26",{"date":137,"type":43},"2024-09-01",{"date":139,"type":23},"2028-03-30",{"name":141,"class":50},"University of Victoria"]