[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"fascia-iliaca-block\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:fascia-iliaca-block":28},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,3,0,[8,46,74],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":4,"eligibilityCriteria":15,"healthyVolunteers":11,"sex":16,"minAge":17,"maxAge":4,"enrollmentInfo":18,"targetDuration":4,"studyType":21,"phases":22,"briefSummary":24,"conditions":25,"keywords":31,"overallStatus":33,"whyStopped":4,"lastUpdateSubmitDate":34,"lastUpdatePostDateStruct":35,"startDateStruct":38,"completionDateStruct":40,"leadSponsor":42,"locationsCount":45},"100642566","phase-4-fascia-iliaca-block-using-liposomal-bupivacaine-for-analgesia-after-hip-fracture-surgery-100642566",false,"NCT07643792","Fascia Iliaca Block Using Liposomal Bupivacaine for Analgesia After Hip Fracture Surgery","Fascia Iliaca Block Using Liposomal Bupivacaine for Analgesia After Hip Fracture Surgery: a Randomized Trial","Inclusion Criteria:\n\n* Aged ≥ 55 years.\n* Diagnosed as hip fracture and scheduled to undergo hip replacement surgery.\n* Agree to receive regional nerve block and postoperative patient-controlled intravenous analgesia (PCIA).\n\nExclusion Criteria:\n\n* Inability to communicate due to visual, auditory, language, or other reasons before surgery.\n* Chronic opioid dependence and long-term use of various types of analgesics (for more than 3 months).\n* Severe coagulation abnormalities (International Normalized Ratio \\> 1.7, activated partial thromboplastin time exceeding the normal value by more than 4 seconds, platelet count \\\u003C 80 × 10⁹\u002FL), trauma or infection at the intended puncture site, or severe low back pain.\n* Preoperative severe renal insufficiency (serum creatinine \\> 442 μmol\u002FL or requiring renal replacement therapy), hepatic insufficiency (Child-Pugh class C), or ASA physical status \\> IV.\n* Known allergy to local anesthetics.\n* Any other condition that the investigator or attending physician deems unsuitable for participation in the study.","ALL","55 Years",{"count":19,"type":20},148,"ESTIMATED","INTERVENTIONAL",[23],"PHASE4","Older patients with hip fractures often suffer from severe pain. Inadequate analgesia increases the risk of postoperative delirium, myocardial injury, and other complications. Peripheral nerve block is an important component of multimodal analgesia, but conventional local anesthetics (such as plain bupivacaine) provide only approximately 12 hours of analgesic duration, which is far from covering the most painful 72 hours after surgery. Liposomal bupivacaine has a slow-release property, prolonging the analgesic duration up to 72 hours after a single injection. However, its clinical advantages in hip fracture surgery remain controversial. The investigators suppose that, compared with plain bupivacaine alone, preoperative supra-inguinal fascia iliaca block using liposomal bupivacaine combined with plain bupivacaine can further improve analgesia, decrease opioid consumption, and improve postoperative recovery quality within 72 hours in older patients after hip fracture surgery.",[26,27,28,29,30],"Older Adults","Hip Fracture Surgery","Fascia Iliaca Block","Liposomal Bupivacaine","Postoperative Pain",[26,32,28,29,30],"Hip fracture surgery","NOT_YET_RECRUITING","2026-06-11",{"date":36,"type":37},"2026-06-15","ACTUAL",{"date":39,"type":20},"2026-07",{"date":41,"type":20},"2028-08",{"name":43,"class":44},"Peking University First Hospital","OTHER",1,{"id":47,"slug":48,"hasResults":11,"nctId":49,"briefTitle":50,"officialTitle":51,"acronym":4,"eligibilityCriteria":52,"healthyVolunteers":11,"sex":16,"minAge":53,"maxAge":54,"enrollmentInfo":55,"targetDuration":4,"studyType":21,"phases":57,"briefSummary":59,"conditions":60,"keywords":4,"overallStatus":64,"whyStopped":4,"lastUpdateSubmitDate":65,"lastUpdatePostDateStruct":66,"startDateStruct":68,"completionDateStruct":70,"leadSponsor":72,"locationsCount":45},"100575553","transcatheter-aortic-valve-implantation-comparison-of-the-effects-of-ultrasound-guided-pericapsular-nerve-group-block-and-fascia-iliaca-block-on-postoperative-analgesia-management-100575553","NCT06773780","Transcatheter Aortic Valve Implantation: Comparison of the Effects of Ultrasound-Guided Pericapsular Nerve Group Block and Fascia Iliaca Block on Postoperative Analgesia Management","Transcatheter Aortic Valve Implantation: Comparison of the Effects of Ultrasound-Guided Pericapsular Nerve Group Block and Fascia Iliaca Block on Postoperative Analgesia Management - A Randomized, Prospective Study","Inclusion Criteria:\n\n* Patients scheduled for TAVİ\n* aged between 18 and 85 years,\n* American Society of Anesthesiology (ASA) physical status II-IV\n\nExclusion Criteria:\n\n* History of bleeding diathesis.\n* Use of anticoagulant therapy.\n* History of chronic pain prior to surgery.\n* Multiple trauma.\n* Conditions where pain assessment cannot be performed (e.g., dementia).\n* Patients operated under spinal or epidural anesthesia.\n* Presence of infection in the region where the block will be applied.\n* Refusal to consent to the procedure","18 Years","85 Years",{"count":56,"type":20},60,[58],"NA","Aortic Stenosis (AS) is the most common valvular pathology, particularly prevalent in advanced age, and Transcatheter Aortic Valve Implantation (TAVI) has become a crucial treatment option for high-risk patients who are not suitable for surgery. This minimally invasive approach has demonstrated successful clinical outcomes in patients deemed ineligible for surgical procedures.\n\nPatient selection criteria and advancements in operative techniques are critical for achieving successful TAVI outcomes. While the transfemoral approach is the most commonly used method, alternative techniques such as transapical, transaxillary, transcarotid, and transaortic approaches are also available.\n\nThe Pericapsular Nerve Group Block (PENG) targets the femoral and accessory obturator nerves, providing analgesia to the anterior hip without causing motor block. The Fascia Iliaca Block (FIB), on the other hand, provides broader analgesic coverage by affecting the lateral femoral cutaneous, obturator, and femoral nerves.\n\nThis study aims to compare PENG block, FIB, and local infiltration anesthesia in TAVI patients regarding sedation requirements during the procedure and postoperative analgesia management. Additionally, pain scores, motor block presence, opioid consumption, and side effects will be assessed. The study seeks to identify optimal strategies to enhance patient comfort and safety during TAVI procedures.",[61,62,63,28],"Aortic Valve Stenosis","Transcatheter Aortic Valve Implantation","Pericapsular Nerve Group Block","RECRUITING","2025-12-01",{"date":67,"type":37},"2025-12-02",{"date":69,"type":37},"2025-01-10",{"date":71,"type":20},"2026-12-01",{"name":73,"class":44},"Medipol University",{"id":75,"slug":76,"hasResults":11,"nctId":77,"briefTitle":78,"officialTitle":78,"acronym":4,"eligibilityCriteria":79,"healthyVolunteers":11,"sex":16,"minAge":53,"maxAge":80,"enrollmentInfo":81,"targetDuration":4,"studyType":21,"phases":83,"briefSummary":85,"conditions":86,"keywords":88,"overallStatus":64,"whyStopped":4,"lastUpdateSubmitDate":92,"lastUpdatePostDateStruct":93,"startDateStruct":95,"completionDateStruct":97,"leadSponsor":98,"locationsCount":45},"100563272","phase-1-effect-of-different-administration-routes-of-dexmedetomidine-combined-with-ultrasound-guided-fascia-iliaca-block-on-emergence-agitation-after-hip-replacement-surgery-100563272","NCT06614010","Effect of Different Administration Routes of Dexmedetomidine Combined with Ultrasound-Guided Fascia Iliaca Block on Emergence Agitation After Hip Replacement Surgery","Inclusion Criteria:\n\n1. age between 18 and 65 years, with no restriction on gender\n2. diagnosis of hip joint disease necessitating hip arthroplasty\n3. ASA grade I-II\n4. no significant cardiopulmonary, hepatic, or renal dysfunction prior to the operation\n5. no history of psychiatric disorders or long-term use of sedative medications prior to the operation\n6. signing of an informed consent form to voluntarily participate in the study.\n\nExclusion Criteria:\n\n1. patients allergic to or with contraindications to ropivacaine or dexmedetomidine\n2. patients exhibiting symptoms of agitation or delirium prior to the procedure\n3. patients with severe central or peripheral nervous system disorders\n4. patients with coagulation disorders or receiving anticoagulant therapy\n5. pregnant or breastfeeding women\n6. patients who received other medications or treatments prior to the procedure that might affect the study results\n7. patients unable to cooperate with the study or intolerant to ultrasound-guided iliofascial block","65 Years",{"count":82,"type":20},207,[84],"PHASE1","To examine the impact of various administration routes of dexmedetomidine in conjunction with ultrasound-guided fascia iliaca block (FIB) on emergence agitation (EA) during the postoperative recovery period after hip replacement surgery.",[87,28],"Dexmedetomidine",[28,87,89,90,91],"Emergence Agitation","Ropivacaine","Analgesic Mechanism","2024-09-23",{"date":94,"type":37},"2024-09-26",{"date":96,"type":37},"2023-02-05",{"date":65,"type":20},{"name":99,"class":44},"Qianfoshan Hospital"]