[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"febrile-illnesses\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:febrile-illnesses":27},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,1,0,[8],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":15,"eligibilityCriteria":16,"healthyVolunteers":11,"sex":17,"minAge":18,"maxAge":4,"enrollmentInfo":19,"targetDuration":22,"studyType":23,"phases":4,"briefSummary":24,"conditions":25,"keywords":31,"overallStatus":37,"whyStopped":4,"lastUpdateSubmitDate":38,"lastUpdatePostDateStruct":39,"startDateStruct":42,"completionDateStruct":44,"leadSponsor":46,"locationsCount":5},"100614369","the-fever-clinic-acute-respiratory-cohort-100614369",false,"NCT07278700","The Fever Clinic Acute Respiratory Cohort","The Fever Clinic Acute Respiratory Cohort (FACTS): A Prospective Real-World Cohort Study of Patients Presenting to Fever Clinics: Clinical Features, Laboratory and Radiographic Findings, and Long-Term Outcomes of Acute Respiratory Infections","FACTS","Inclusion Criteria:\n\n* Age ≥ 18 years (based on official identification document).\n* Presence of fever at the time of visit or within 24 hours prior to the visit, defined as a documented temperature of ≥37.3°C axillary\u002Ftympanic, ≥37.8°C orally, or ≥38.0°C rectally.\n* The primary cause of fever, as determined by the attending physician, is a respiratory tract infection.\n* Blood draw is required as part of standard clinical care.\n* Ability to comprehend the study's purpose, procedures, and potential risks, and willingness to provide written informed consent.\n\nExclusion Criteria:\n\n* Inability to provide independent informed consent due to impaired consciousness or other reasons.\n* Inability to comply with the study procedures.\n* Medical contraindications to blood sampling, such as severe coagulopathy (e.g., INR \\> 3.0, platelet count \\\u003C 50 × 10⁹\u002FL).\n* Diagnosed with a terminal illness (e.g., advanced malignancy, severe multiple organ failure) and a life expectancy of less than 3 months.","ALL","18 Years",{"count":20,"type":21},1000,"ESTIMATED","30 Days","OBSERVATIONAL","This prospective cohort study aims to characterize the natural progression and outcomes of acute respiratory infections among patients presenting to fever clinics. At enrollment, patients' clinical symptoms, laboratory findings, and chest imaging data will be collected. Longitudinal follow-up will be conducted to evaluate disease progression, complications, and long-term outcomes.\n\nAs an observational study, no interventions are involved; all patients receive routine clinical management as directed by their attending physicians. This real-world study design enables the assessment of the natural course of acute respiratory infections and the identification of factors associated with clinical outcomes.",[26,27,28,29,30],"Acute Respiratory Infections","Febrile Illnesses","Community-acquired Pneumonia","Viral Respiratory Tract Infections","Influenza-like Illness",[32,33,34,35,36],"Respiratory Tract Infections","Fever","Community-Acquired Pneumonia","Anti-Bacterial Agents","Disease Progression","RECRUITING","2025-12-11",{"date":40,"type":41},"2025-12-12","ACTUAL",{"date":43,"type":41},"2025-10-10",{"date":45,"type":21},"2028-10",{"name":47,"class":48},"Fudan University","OTHER"]