[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"feces\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:feces":35},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,2,0,[8,61],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":13,"acronym":14,"eligibilityCriteria":15,"healthyVolunteers":16,"sex":17,"minAge":4,"maxAge":18,"enrollmentInfo":19,"targetDuration":4,"studyType":22,"phases":23,"briefSummary":25,"conditions":26,"keywords":42,"overallStatus":49,"whyStopped":4,"lastUpdateSubmitDate":50,"lastUpdatePostDateStruct":51,"startDateStruct":54,"completionDateStruct":56,"leadSponsor":58,"locationsCount":5},"100609268","infant-microbiota-restoration-with-maternal-microbes-100609268",false,"NCT07212361","Infant Microbiota Restoration With Maternal Microbes","MaMi","Inclusion Criteria:\n\n* Healthy mother and healthy pregnancy\n* Singleton pregnancy,\n* Mothers who speak Finnish or Swedish\n* Mothers who are planning to breastfeed or give breastmilk by bottle to the infant\n* Infants who are expected to be healthy and who will not require BCG vaccination.\n\nExclusion Criteria:\n\n* Participants who lives further than a 2-hour drive from Meilahti, Helsinki, Finland\n* Mothers who are not planning to breastfeed or feed breastmilk by bottle to the infant\n* Mothers who are diagnosed with gestational diabetes, pre-eclampsia or who have been receiving antibiotics during the pregnancy or delivery\n* Premature infants born before the pregnancy week 37\n* Infants, who are born by urgent cesarean section or emergency cesarean section\n* Infants, who receive antibiotics during the first week of life\n* Infants, who are diagnosed with a disease, congenital anomaly or who receive less than 9 Apgar points at 5 minutes.\n* Infants, who receive BCG-vaccine",true,"ALL","50 Years",{"count":20,"type":21},100,"ESTIMATED","INTERVENTIONAL",[24],"NA","The goal of this clinical trial is to test the ability of different bacterial products in restoring natural gut microbiota in C-section born infants. The main question it aims to answer is:\n\nDo maternally derived strains of bacteria perform better than commercially available probiotic strains in restoring the gut microbiota of C-section born infants? Researchers will compare the gut microbiota of treated infants to that of untreated C-section born infants and untreated vaginally born infants to see if the bacterial treatments cause the microbiota to resemble that of vaginally born infants.\n\nParticipants will be given a bacterial product orally once daily for either one or four weeks and be asked to collect faecal, urine and saliva samples.",[27,28,29,30,31,32,33,34,35,36,37,38,39,40,41],"Infant, Newborn","Gut -Microbiota","Gut Dysbiosis","Cesarean Delivery Affecting Newborn","Cesarean Section","Vaginal Delivery","Gastrointestinal Microbiota","Microbiota, Cesarean Section, Probiotics, Dysbiosis","Feces","Delivery, Obstetric","Microbiota","Microbiology","Humans","Pregnancy","Neonate",[43,44,45,46,47,48],"Infant","newborn","cesarean section","neonate","restore","gut microbiota","RECRUITING","2025-09-30",{"date":52,"type":53},"2025-10-08","ACTUAL",{"date":55,"type":53},"2025-07-17",{"date":57,"type":21},"2035-12-31",{"name":59,"class":60},"University of Helsinki","OTHER",{"id":62,"slug":63,"hasResults":11,"nctId":64,"briefTitle":65,"officialTitle":65,"acronym":4,"eligibilityCriteria":66,"healthyVolunteers":16,"sex":17,"minAge":4,"maxAge":67,"enrollmentInfo":68,"targetDuration":4,"studyType":69,"phases":4,"briefSummary":70,"conditions":71,"keywords":4,"overallStatus":49,"whyStopped":4,"lastUpdateSubmitDate":74,"lastUpdatePostDateStruct":75,"startDateStruct":77,"completionDateStruct":79,"leadSponsor":81,"locationsCount":83},"100474781","omics-sequencing-of-specimen-derived-from-mother-infant-pairs-100474781","NCT05462366","Omics Sequencing of Specimen Derived From Mother-Infant-Pairs","Inclusion Criteria:\n\n* healthy pregnant women aged between 20y and 40y.\n* Vaginal birth\n* BMI\\\u003C23.5 before pregnancy\n* Infants' birth weight, between 2500g and 4000g.\n\nExclusion Criteria:\n\n* gestational diabetes\n* diagnosis of depressive disorder during pregnancy\n* gestational hypertension\n* diagnosis of other diseases during pregnancy\n* Under probiotics or antibiotic treatment from 3 months prior to pregnancy till 3 months after delivery\n* histrory of smoking and drinking alcohol\n* history of diarrhea from 3 months prior to pregnancy till 3 months after delivery","40 Years",{"count":20,"type":21},"OBSERVATIONAL","The investigators aim to collect breast-milk and feces from the participants, and apply culture techniques as well as omics sequencing technology to probe into the microbial and metabolomic signature of the specimens.",[72,73,35],"Healthy","Breast-milk Collection","2023-07-22",{"date":76,"type":53},"2023-07-25",{"date":78,"type":53},"2021-06-22",{"date":80,"type":21},"2026-12-30",{"name":82,"class":60},"Zhujiang Hospital",1]