[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"feeding-difficult-newborn\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:feeding-difficult-newborn":29},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,3,0,[8,44,69],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":4,"eligibilityCriteria":15,"healthyVolunteers":16,"sex":17,"minAge":18,"maxAge":19,"enrollmentInfo":20,"targetDuration":4,"studyType":23,"phases":24,"briefSummary":26,"conditions":27,"keywords":4,"overallStatus":31,"whyStopped":4,"lastUpdateSubmitDate":32,"lastUpdatePostDateStruct":33,"startDateStruct":36,"completionDateStruct":38,"leadSponsor":40,"locationsCount":43},"100408479","role-of-body-composition-in-large-for-gestational-age-infants-lga-with-oral-feeding-difficulty-100408479",false,"NCT04599010","Role of Body Composition in Large for Gestational Age Infants (LGA) With Oral Feeding Difficulty","Pilot Randomized Controlled Trial Comparing FFM-indexed Feeding vs. Standard Feeding in LGA Infants With Oral Feeding Difficulty and Disproportionate Body Composition.","Inclusion Criteria:\n\n* LGA infants with oral feeding difficulty born at ≥ 35 weeks gestation, with FM z-score \\> +1.0 in body composition measurement\n\nExclusion Criteria:\n\n* Infants on any respiratory support, Infants on enteral feeding duration \\> 60 minutes due to hypoglycemia concerns, videofluoroscopic swallow study (VFSS) demonstrating unsafe swallowing function, GI surgical conditions, significant neurological morbidities, and major congenital, genetic syndromes\u002Fanomalies",true,"ALL","1 Week","10 Weeks",{"count":21,"type":22},40,"ESTIMATED","INTERVENTIONAL",[25],"NA","Large for Gestational Age (LGA) infants have excess fat-mass (FM) proportion secondary to prolonged in utero exposure to an energy-rich environment. Our preliminary data suggest that excess FM proportion can be associated with oral feeding delay and a potentially modifiable therapeutic target to improve oral feeding outcomes. The objective of this study is to determine the impact of a short-term Fat-free mass (FFM)-indexed feeding on the oral intake volumes in LGA infants with oral feeding difficulties.",[28,29,30],"Body Composition","Feeding; Difficult, Newborn","Nutrition Disorder, Infant","RECRUITING","2026-05-22",{"date":34,"type":35},"2026-05-27","ACTUAL",{"date":37,"type":35},"2024-09-26",{"date":39,"type":22},"2027-12-31",{"name":41,"class":42},"Nemours Children's Clinic","OTHER",2,{"id":45,"slug":46,"hasResults":11,"nctId":47,"briefTitle":48,"officialTitle":49,"acronym":4,"eligibilityCriteria":50,"healthyVolunteers":16,"sex":17,"minAge":51,"maxAge":4,"enrollmentInfo":52,"targetDuration":4,"studyType":23,"phases":54,"briefSummary":55,"conditions":56,"keywords":4,"overallStatus":31,"whyStopped":4,"lastUpdateSubmitDate":59,"lastUpdatePostDateStruct":60,"startDateStruct":62,"completionDateStruct":64,"leadSponsor":66,"locationsCount":68},"100548160","tavns-paired-breastfeeding-to-improve-breastfeeding-at-discharge-100548160","NCT06417385","taVNS-Paired Breastfeeding to Improve Breastfeeding at Discharge","Transcutaneous Auricular Vagus Nerve Stimulation (taVNS)-Paired Breastfeeding to Improve Breastfeeding at Discharge","Inclusion Criteria:\n\n* Infants ≥ 35 weeks post-menstrual age,\n* Clinically stable, without significant respiratory support,\n* Deemed safe to breastfeed by OT\u002FSLP\u002Flactation,\n* Maternal interest in breastfeeding,\n* Are not breastfeeding well despite the assistance of a lactation consultant.\n\nExclusion Criteria:\n\n* Cardiomyopathy,\n* Unstable bradycardia,\n* Significant respiratory support,\n* Absent maternal interest in breastfeeding, or infant or mother with contraindications to breastfeeding such as infantile galactosemia,\n* Maternal HIV without adequate viral suppression,\n* Maternal illicit drug use.","35 Weeks",{"count":53,"type":22},10,[25],"Investigators aim to improve the skills of premature or sick term infants in breastfeeding by boosting motor learning with transcutaneous vagus nerve stimulation. Investigators will recruit 10 premature, ≥ 35 weeks gestational age, or convalescing sick term infants admitted to the NICU at MUSC to participate in this study. Infants will receive taVNS treatments once a day with breastfeeding's for up to 14 days. Before each treatment, the researcher will determine how much electrical stimulation is needed for the infant to feel a slight tingle without discomfort, and during daily treatment paired with breastfeeding the infant will continue to receive this level of electrical stimulation, coinciding with latching and sucking, repeated over the duration of the feed. Investigators will collect information about the pre- and post-feed weights, the length of time for each feed, and observations of latch, suck, and swallow techniques by the infant from parents and the lactation consultant. Investigators will also evaluate parental satisfaction associated with their infant's ability to breastfeed after taVNS by providing parental satisfaction surveys at the beginning, after 1 and 2 weeks, and at 3 months after the end of the study to assess infants' progress in and maintenance of breastfeeding abilities.\n\nIf the pairing of breastfeeding with taVNS is able to result in improved outcomes of effective breastfeeding in infants in the neonatal intensive care units, this intervention could be further utilized by NICUs to increase the rate of premature and sick term infants who are successfully able to breastfeed at the time of discharge and maintain breast feeding longer after discharge. This would allow premature infants to acquire the many benefits of breastmilk as well as contribute towards the strengthening of the maternal-infant bond that breastfeeding has been shown to enhance.",[57,58,29],"Premature Birth","Breastfeeding, Exclusive","2026-02-04",{"date":61,"type":35},"2026-02-06",{"date":63,"type":35},"2024-02-01",{"date":65,"type":22},"2027-06-01",{"name":67,"class":42},"Medical University of South Carolina",1,{"id":70,"slug":71,"hasResults":11,"nctId":72,"briefTitle":73,"officialTitle":74,"acronym":4,"eligibilityCriteria":75,"healthyVolunteers":16,"sex":17,"minAge":76,"maxAge":77,"enrollmentInfo":78,"targetDuration":4,"studyType":23,"phases":80,"briefSummary":81,"conditions":82,"keywords":87,"overallStatus":31,"whyStopped":4,"lastUpdateSubmitDate":94,"lastUpdatePostDateStruct":95,"startDateStruct":97,"completionDateStruct":99,"leadSponsor":101,"locationsCount":68},"100505449","combined-oral-motor-stimulation-and-language-on-preterm-infant-feeding-100505449","NCT05861531","Combined Oral Motor Stimulation and Language on Preterm Infant Feeding","The Combined Association of an Oral Motor Stimulation and Language Intervention on Preterm Infant Feeding","Inclusion Criteria:\n\n* 23-30 weeks\n* English and Spanish speaking\n\nExclusion Criteria:\n\n* Major congenital anomalies\n* Surgical necrotizing enterocolitis\n* Non-English and Non-Spanish speaking","23 Weeks","30 Weeks",{"count":79,"type":22},124,[25],"This is a randomized controlled trial to study an oromotor stimulation in combination with a reading curriculum in the NICU among preterm infants using oral muscle exercises, Language Environment Analysis (LENA) recordings, linguistic feedback, and a language curriculum to improve the neonatal inpatient oral feeding and language outcomes for preterm infants.",[83,84,29,85,86],"Language Delay","Language Development","Mother-Infant Interaction","Maternal Behavior",[88,89,90,91,92,93],"Neonatal feeding","Neonatal language","Oromotor stimulation","Newborn reading","Parent infant interaction","LENA","2025-09-10",{"date":96,"type":35},"2025-09-17",{"date":98,"type":35},"2025-07-01",{"date":100,"type":22},"2030-07-01",{"name":102,"class":42},"Women and Infants Hospital of Rhode Island"]