[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"feeding-patterns\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:feeding-patterns":25},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,4,0,[8,47,76,102],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":13,"acronym":4,"eligibilityCriteria":14,"healthyVolunteers":11,"sex":15,"minAge":16,"maxAge":4,"enrollmentInfo":17,"targetDuration":4,"studyType":20,"phases":21,"briefSummary":23,"conditions":24,"keywords":28,"overallStatus":34,"whyStopped":4,"lastUpdateSubmitDate":35,"lastUpdatePostDateStruct":36,"startDateStruct":39,"completionDateStruct":41,"leadSponsor":43,"locationsCount":46},"100419090","the-impact-of-overnight-nutrition-support-on-sleep-and-circadian-rhythm-disruption-in-the-icu-100419090",false,"NCT04737200","The Impact of Overnight Nutrition Support on Sleep and Circadian Rhythm Disruption in the ICU","Inclusion Criteria:\n\n* Adult male or non-pregnant female volunteers (age 18+)\n* Scheduled for a cardiac surgical procedure with planned post-operative admission to the ICU for \\>48 hours\n* Able and willing to give consent and comply with study procedures\n\nExclusion Criteria:\n\n* Blind, deaf or unable to speak English\n* Women who are pregnant or nursing\n* Contraindications to safe use enteral nutrition, including gastrointestinal obstruction\n* Personal history of intestinal malabsorption, gallbladder disease or pancreatitis\n* Dietary restrictions precluding enteral feeds\n* Renal and liver failure requiring dialysis or Child-Pugh score \\> 7\n* Severe deficit due to structural or anoxic brain damage\n* With skin condition that precludes wearing sensors","ALL","18 Years",{"count":18,"type":19},30,"ESTIMATED","INTERVENTIONAL",[22],"NA","The purpose of this study is to determine whether modifying the timing of nutrition support from overnight to daytime enhances sleep quality, preserves circadian rhythms, and improves overall inflammation and cardiometabolic profiles in postoperative patients in the cardiac surgical ICU on enteral nutrition.",[25,26,27],"Feeding Patterns","Sleep","Glucose Intolerance",[29,30,31,32,33,26],"Enteral Nutrition","Chrononutrition","Intensive Care Unit","Chronobiology","Nutrition Support","RECRUITING","2026-05-18",{"date":37,"type":38},"2026-05-19","ACTUAL",{"date":40,"type":38},"2022-02-08",{"date":42,"type":19},"2027-03-31",{"name":44,"class":45},"Massachusetts General Hospital","OTHER",1,{"id":48,"slug":49,"hasResults":11,"nctId":50,"briefTitle":51,"officialTitle":52,"acronym":4,"eligibilityCriteria":53,"healthyVolunteers":54,"sex":15,"minAge":16,"maxAge":55,"enrollmentInfo":56,"targetDuration":4,"studyType":20,"phases":58,"briefSummary":59,"conditions":60,"keywords":62,"overallStatus":34,"whyStopped":4,"lastUpdateSubmitDate":67,"lastUpdatePostDateStruct":68,"startDateStruct":70,"completionDateStruct":72,"leadSponsor":74,"locationsCount":46},"100584606","circadian-rhythms-in-human-adipose-100584606","NCT06891534","Circadian Rhythms in Human Adipose","Circadian Regulation of Human Adipose Tissue Metabolism","Inclusion Criteria:\n\n* BMI 20-25 kg\u002Fm2 or 30-37 kg\u002Fm2\n* For participants with obesity a waist-to-hip ratio of ≥0.95 in males and ≥0.90 in females.\n* sedentary\n* females: non pregnant or breastfeeding\n* ability to provide written informed consent and follow study instructions\n\nExclusion Criteria:\n\n* History of mediations that impact adipocyte\u002Flipid metabolism\n* smoking\n* insomnia\n* sleep apnea\n* sleep medication use\n* employment in night or shift work\n* extreme chronotypes\n* Allergy to lidocaine",true,"55 Years",{"count":57,"type":19},40,[22],"The goal of this study is to understand the underlying circadian rhythms in subcutaneous adipose tissue of humans with our without continuous feeding and how these are altered in people who have obesity.",[61,25],"Obesity, Abdominal",[63,64,65,66],"circadian rhythms","adipose tissue","obesity","feeding pattern","2026-04-13",{"date":69,"type":38},"2026-04-14",{"date":71,"type":38},"2021-07-01",{"date":73,"type":19},"2030-12",{"name":75,"class":45},"Mayo Clinic",{"id":77,"slug":78,"hasResults":11,"nctId":79,"briefTitle":80,"officialTitle":81,"acronym":4,"eligibilityCriteria":82,"healthyVolunteers":54,"sex":15,"minAge":83,"maxAge":84,"enrollmentInfo":85,"targetDuration":4,"studyType":20,"phases":87,"briefSummary":88,"conditions":89,"keywords":4,"overallStatus":92,"whyStopped":4,"lastUpdateSubmitDate":93,"lastUpdatePostDateStruct":94,"startDateStruct":96,"completionDateStruct":98,"leadSponsor":100,"locationsCount":46},"100559826","cue-based-vs-clinician-driven-feeding-in-very-low-birthweight-infants-100559826","NCT06569186","Cue-Based Vs. Clinician-Driven Feeding in Very Low Birthweight Infants","Cue-Based Vs. Clinician-Driven Feeding in Very Low Birthweight Infants: A Pilot Randomized Trial","Inclusion criteria:\n\n* Birthweight \\\u003C 1500 grams\n* Gestational age between 28 and 31 weeks of gestation\n* Full enteral feeding established before 32 weeks of postmenstrual age (PMA)\n* Oral feeding initiated before 33 weeks PMA.\n\nExclusion criteria:\n\n* Major congenital\u002Fchromosomal anomalies,\n* Patent ductus arteriosus causing significant cardiovascular symptoms\n* History of necrotizing enterocolitis stage 2 or greater","28 Weeks","32 Weeks",{"count":86,"type":19},74,[22],"In this parallel-group randomized controlled trial, very low birthweight infants will be randomly assigned in a 1:1 ratio to either cue-based (intervention group) or clinician-driven feeding (control group). For infants in the intervention group, Speech therapists and nurses will use their cue-based assessment training to aid in clinical management of oral feeding. For infants in the control group, clinicians caring for these infants will define the feeding plan based on their daily assessment.",[90,91,25],"Infant, Very Low Birth Weight","Infant Development","NOT_YET_RECRUITING","2025-08-14",{"date":95,"type":38},"2025-08-15",{"date":97,"type":19},"2026-12",{"date":99,"type":19},"2028-10",{"name":101,"class":45},"University of Alabama at Birmingham",{"id":103,"slug":104,"hasResults":11,"nctId":105,"briefTitle":106,"officialTitle":107,"acronym":4,"eligibilityCriteria":108,"healthyVolunteers":11,"sex":15,"minAge":109,"maxAge":110,"enrollmentInfo":111,"targetDuration":4,"studyType":20,"phases":113,"briefSummary":114,"conditions":115,"keywords":117,"overallStatus":92,"whyStopped":4,"lastUpdateSubmitDate":123,"lastUpdatePostDateStruct":124,"startDateStruct":126,"completionDateStruct":128,"leadSponsor":130,"locationsCount":46},"100550444","continuous-versus-bolus-feeding-in-neonates-with-hypoxic-ischemic-encephalopathy-100550444","NCT06447155","Continuous Versus Bolus Feeding in Neonates With Hypoxic Ischemic Encephalopathy","The Impact of Continuous Versus Bolus Feeding in Neonates With Hypoxic Ischemic Encephalopathy Undergoing Therapeutic Hypothermia","Inclusion Criteria:\n\n* The neonates with evidence of encephalopathy de¬fined by seizures or abnormalities on a modified Sarnat exam were enrolled. The hypoxic-ischemic injury was defined by 1. a pH of ≤ 7.0 and\u002For 2. base deficit \\>-16 mmol\u002FL recorded in cord blood or blood gas obtained within the first hour postnatally or a pH of 7.0 - 7.15 and\u002For base deficit (-10-15.9) mmol\u002FL with the presence of an acute perinatal event (cord prolapse, placental abruption, heart rate decelerations, severe fetal bradycardia). In cases where criteria 1 or 2 are met, with the presence of seizures or a diagnosis of moderate to severe encephalopathy according to the Sarnat \\& Sarnat classification based on neurological examination were treated with TH.\n\nExclusion Criteria: Infants with congenital malformation or hereditary metabolic diseases, infants whose enteral feeding was initiated before randomization and infants without lack of parental consent were excluded. The maternal and neonatal demographic characteristics and clinical outcomes were collected from medical records.\n\n\\-","0 Days","1 Day",{"count":112,"type":19},60,[22],"Therapeutic hypothermia (TH) is accepted worldwide as a standard of care for infants born at or beyond 36 weeks gestational age with moderate-to-severe hypoxic ischaemic encephalopathy (HIE).\n\nWhile central nervous system is the most affected organ system , multiorgan dysfunction including renal, pulmonary, cardiac, and\u002For gastrointestinal (GI) compromise is not infrequent. Although the process of 'cooling' itself is well defined, based on high-quality randomized controlled trials, there are few data to inform the provision of nutrition to infants with HIE during and soon after TH.However, breastfeeding plays a beneficial role in maintaining the structural and functional integrity of the gut. It may help to reduce systemic inflammatory response and positively regulates the microbiota. In many studies it is stated that enteral feeding during TH appears to be safe and feasible. There is insufficient evidence to choose the type of enteral feeding either bolus or continuous during TH.\n\nThe present study aimed to compare the impact of different types of enteral feeding in infants with HIE receiving TH.",[116,25],"Hypoxic Ischemic Encephalopathy of Newborn",[118,119,120,121,122],"Newborn","Hypoxic ischemic encephalopathy","Enteral feeding","Bolus","Continuous","2024-06-03",{"date":125,"type":38},"2024-06-06",{"date":127,"type":19},"2024-06-15",{"date":129,"type":19},"2026-06-15",{"name":131,"class":132},"Istanbul Training and Research Hospital","OTHER_GOV"]