[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"femoral-fractures\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:femoral-fractures":24},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,6,0,[8,44,69,99,124,146],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":4,"eligibilityCriteria":15,"healthyVolunteers":11,"sex":16,"minAge":17,"maxAge":4,"enrollmentInfo":18,"targetDuration":4,"studyType":21,"phases":4,"briefSummary":22,"conditions":23,"keywords":27,"overallStatus":31,"whyStopped":4,"lastUpdateSubmitDate":32,"lastUpdatePostDateStruct":33,"startDateStruct":36,"completionDateStruct":38,"leadSponsor":40,"locationsCount":43},"100628570","preoperative-oral-nutrition-and-outcomes-in-frail-elderly-patients-with-femur-fractures-100628570",false,"NCT07463352","Preoperative Oral Nutrition And Outcomes In Frail Elderly Patients With Femur Fractures","Evaluation of the Effects of Preoperative Oral Nutritional Support on Hemodynamic Stability, Morbidity, Mortality, and Anthropometric Measurements in Patients With Femur Fractures and High Frailty Index: A Prospective Observational Study","Inclusion Criteria:\n\n* Patients aged 65 years or older hospitalized with a diagnosis of femur fracture\n* High frailty index (Clinical Frailty Scale ≥ 5)\n* Patients expected to require postoperative intensive care\n\nExclusion Criteria:\n\n* Patients requiring preoperative intensive care\n* Patients unable to tolerate enteral nutrition\n* Patients with advanced liver or kidney failure\n* Patients unable to cooperate\n* Patients with neuromuscular disease\n* Patients with severe malnutrition according to NRS-2002 guidelines\n* Patients who refuse to participate","ALL","65 Years",{"count":19,"type":20},228,"ESTIMATED","OBSERVATIONAL","The goal of this observational study is to learn whether preoperative oral nutrition support improves clinical outcomes in elderly patients with femur fractures who have a high frailty index. The main questions it aims to answer are:\n\n* Does preoperative nutrition support improve hemodynamic stability during and after surgery?\n* Does it reduce postoperative complications, mortality, and length of hospital stay?\n\nResearchers will compare patients who receive preoperative oral nutrition support with those who follow routine nutrition.\n\nParticipants will:\n\n* Receive routine medical care with or without nutrition support\n* Have their hemodynamic values, complications, and outcomes recorded during hospitalization\n* Be followed at 30 and 90 days after surgery for complications and mortality.",[24,25,26],"Femoral Fractures","Frailty","Malnutrition",[28,29,25,26,30],"Hip Fractures","Geriatric Patients","Hemodynamic Stability","RECRUITING","2026-06-15",{"date":34,"type":35},"2026-06-16","ACTUAL",{"date":37,"type":35},"2026-03-12",{"date":39,"type":20},"2027-01-01",{"name":41,"class":42},"Duzce University","OTHER",1,{"id":45,"slug":46,"hasResults":11,"nctId":47,"briefTitle":48,"officialTitle":49,"acronym":4,"eligibilityCriteria":50,"healthyVolunteers":11,"sex":16,"minAge":51,"maxAge":4,"enrollmentInfo":52,"targetDuration":4,"studyType":54,"phases":55,"briefSummary":57,"conditions":58,"keywords":4,"overallStatus":59,"whyStopped":4,"lastUpdateSubmitDate":60,"lastUpdatePostDateStruct":61,"startDateStruct":63,"completionDateStruct":65,"leadSponsor":67,"locationsCount":4},"100614282","combined-nail-and-plate-fixation-in-proximal-femoral-fractures-with-lateral-wall-deficiency-100614282","NCT07277569","Combined Nail and Plate Fixation in Proximal Femoral Fractures With Lateral Wall Deficiency","Nail Plate Construct in Proximal Femoral Fractures With Lateral Wall Deficiency in Skeletally Mature Patients: A Case Series Study.","Inclusion Criteria:\n\n* Skeletally mature patients\n* AO trochanteric fractures 31A2 or 31A3 with lateral wall thickness \\> 20.5 mm on pre-operative radiographs\n* Injury Severity Score (ISS) ≤ 17\n\nExclusion Criteria:\n\n* Open fractures (Gustilo-Anderson type III)\n* Delayed presentation \\> 3 weeks\n* Uncontrolled comorbidities (e.g., uncontrolled diabetes or hypertension; cardiac, renal, hepatic, or respiratory failure)","18 Years",{"count":53,"type":20},17,"INTERVENTIONAL",[56],"NA","Proximal femoral fractures are a major cause of hospitalization and disability worldwide (1). They are commonly seen among elderly patients after low-energy trauma and in younger adults after high-energy injuries and represent a major challenge in orthopaedic management (2) (3).\n\nThese fractures pose unique biomechanical challenges because of axial compression, bending forces and the strong muscle pull that leads to flexion, abduction and external rotation of the proximal fragment (4). Operative management aims to restore anatomical alignment and length to allow early mobilization and weight bearing (5).\n\nIntramedullary devices are widely considered the preferred option for fixation of intertrochanteric fractures, including both stable and unstable types. Their biomechanical advantages include a shorter lever arm, load sharing properties, reduced bending forces, prevention of proximal fragment lateral migration, nearing to the weight-bearing axis, supporting the medial calcar, and allowance for controlled impaction. Clinically, intramedullary nails are also associated with shorter operative time, less soft tissue dissection, reduced blood loss, and earlier mobilization, leading to improved functional outcomes (6-10).\n\nThe integrity of the lateral trochanteric wall plays a crucial role in construct stability by serving as a lateral buttress. Loss of this support results in uncontrolled collapse, medialization of the femoral shaft, excessive varus deformity, and limb shortening (11-12). In a cadaveric investigation, Nie et al. (13) reported that the proximal femoral nail provides adequate support to the medial wall but fails to sufficiently stabilize the lateral wall. Furthermore, clinical evidence has shown that approximately 22% of patients with lateral wall disruption required re-operation due to unsatisfactory initial fixation (14).\n\nTo address these challenges, recent studies have proposed combined fixation using an intramedullary nail augmented with a lateral plate, aiming to enhance stability, prevent varus collapse, and improve clinical outcomes in complex proximal femoral fractures (15).\n\nHowever, evidence supporting this combined approach remains limited, with most available studies being small in scale and heterogeneous. Therefore, reporting outcomes from a case series may provide valuable insights into the feasibility, safety, and effectiveness of combined nail-plate fixation, and may serve as a foundation for future comparative studies.",[24],"NOT_YET_RECRUITING","2025-12-13",{"date":62,"type":35},"2025-12-19",{"date":64,"type":20},"2026-01-01",{"date":66,"type":20},"2030-01-01",{"name":68,"class":42},"Assiut University",{"id":70,"slug":71,"hasResults":11,"nctId":72,"briefTitle":73,"officialTitle":74,"acronym":4,"eligibilityCriteria":75,"healthyVolunteers":11,"sex":16,"minAge":51,"maxAge":4,"enrollmentInfo":76,"targetDuration":4,"studyType":54,"phases":78,"briefSummary":79,"conditions":80,"keywords":85,"overallStatus":59,"whyStopped":4,"lastUpdateSubmitDate":90,"lastUpdatePostDateStruct":91,"startDateStruct":93,"completionDateStruct":95,"leadSponsor":97,"locationsCount":4},"100593595","effects-of-music-on-preoperative-anxiety-in-patients-with-femoral-fractures-undergoing-surgery-100593595","NCT07008482","Effects of Music on Preoperative Anxiety in Patients With Femoral Fractures Undergoing Surgery","Effects of Music on Preoperative Anxiety in Patients With Femoral Fractures Scheduled for Surgical Intervention: A Randomized Controlled Study","Inclusion Criteria:\n\n* Patients of both sexes, 18 years of age or older\n* Patients with femur fracture who are candidates for surgery\n* Able to provide informed consent.\n\nExclusion Criteria:\n\n* Patients with a diagnosis of hearing loss\n* Patients diagnosed with cognitive or psychiatric disorders\n* Patients undergoing emergency\u002Femergency surgery",{"count":77,"type":20},154,[56],"This randomized controlled trial (RCT) investigates the effectiveness of music therapy in reducing preoperative anxiety among elderly patients with femoral fractures. Preoperative anxiety is known to worsen physiological stability, increase pain perception, and negatively impact recovery, yet specific evidence on non-pharmacological interventions like music therapy in the orthogeriatric setting is lacking.\n\nThe study will enroll 154 adult patients admitted to the Orthogeriatrics Unit for elective femoral fracture surgery. Participants will be randomly assigned to receive either a 20-minute session of music therapy or standard care. Anxiety will be measured using the APAIS scale, and pain will be assessed with the NRS scale, both before and after the intervention.\n\nThe trial is designed as a blinded, prospective RCT, with data collected and managed under current privacy regulations. By generating robust data on this low-cost, safe intervention, the study aims to improve preoperative management and patient outcomes in orthopedic surgical care.",[81,82,83,24,84],"Anxiety","Pain","Surgery","Music Therapy",[86,87,88,89],"NURSING","MUSICTHERAPY","ANXIETY","PAIN","2025-08-11",{"date":92,"type":35},"2025-08-12",{"date":94,"type":20},"2025-09",{"date":96,"type":20},"2026-07",{"name":98,"class":42},"Azienda Unita Sanitaria Locale di Piacenza",{"id":100,"slug":101,"hasResults":11,"nctId":102,"briefTitle":103,"officialTitle":104,"acronym":4,"eligibilityCriteria":105,"healthyVolunteers":11,"sex":16,"minAge":51,"maxAge":4,"enrollmentInfo":106,"targetDuration":4,"studyType":21,"phases":4,"briefSummary":108,"conditions":109,"keywords":111,"overallStatus":59,"whyStopped":4,"lastUpdateSubmitDate":114,"lastUpdatePostDateStruct":115,"startDateStruct":117,"completionDateStruct":119,"leadSponsor":121,"locationsCount":43},"100584132","cocrmo-lock-bipolar-femoral-heads-fu-100584132","NCT06885359","CoCrMo LOCK Bipolar Femoral Heads FU","A Post-market Study Evaluating Clinical and Safety Outcomes of Bipolar Hemiarthroplasty Using CoCrMo LOCK Bipolar Femoral Heads in Subjects with Hip Fracture","Inclusion Criteria:\n\n* Displaced intracapsular hip fracture (Garden III-IV).\n* Subjects underwent a Bipolar Hemiarthroplasty with a CoCrMo LOCK Bipolar femoral head as per their Indication For Use from January 1st, 2023, onwards.\n* No concurrent joint disease at the time of the surgery.\n* Absence of severe cognitive dysfunction demonstrated by 3 or more correct answers on the Pfeiffer test.\n* Ability to ambulate independently with or without walking aids before surgery.\n* Subject willingness to participate.\n\nExclusion Criteria:\n\n* Undisplaced or minimally displaced intracapsular hip fracture (Garden I-II).\n* Any CoCrMo LOCK Bipolar femoral head contraindication for use as reported in the current Instruction For Use.\n* Pathological fracture secondary to malignant disease.\n* Subjects with rheumatoid arthritis or symptomatic osteoarthritis.\n* Previous treatment to the same hip for a fracture at the time of the surgery.\n* Subjects who were deemed unsuitable for the surgical procedures by the anesthesiologist.\n* Severe cognitive dysfunction or cognitive impairment demonstrated by 2 or less correct answers on the Pfeiffer test.\n* Unable to walk before surgery (e.g., wheelchair or bed-ridden subjects).",{"count":107,"type":20},60,"Study design: monocentric, retrospective, observational and post-market clinical study.\n\nPurpose: To demonstrate the safety and performance of CoCrMo LOCK bipolar femoral heads. The eligible study population is represented by the entire population that underwent a hip replacement with CoCrMo LOCK bipolar femoral heads from 1st January 2023 onwards at the site in accordance with the indication for use of the product.",[24,110],"Hip Arthropathy",[112,113],"Femoral head","Partial Hip Arthroplasty","2025-03-24",{"date":116,"type":35},"2025-03-26",{"date":118,"type":20},"2025-10",{"date":120,"type":20},"2028-12",{"name":122,"class":123},"Limacorporate S.p.a","INDUSTRY",{"id":125,"slug":126,"hasResults":11,"nctId":127,"briefTitle":128,"officialTitle":129,"acronym":4,"eligibilityCriteria":130,"healthyVolunteers":11,"sex":16,"minAge":51,"maxAge":4,"enrollmentInfo":131,"targetDuration":4,"studyType":21,"phases":4,"briefSummary":133,"conditions":134,"keywords":136,"overallStatus":59,"whyStopped":4,"lastUpdateSubmitDate":139,"lastUpdatePostDateStruct":140,"startDateStruct":142,"completionDateStruct":143,"leadSponsor":145,"locationsCount":43},"100583226","cephalic-femoral-heads-follow-up-100583226","NCT06873568","Cephalic Femoral Heads Follow Up","A Post-market Study Evaluating Clinical and Safety Outcomes of Unipolar Hemiarthroplasty Using Cephalic Femoral Heads in Subjects with Hip Fracture","Inclusion Criteria:\n\n* Displaced intracapsular hip fracture (Garden III-IV).\n* Subjects underwent a Unipolar Hemiarthroplasty with a Cephalic femoral head as per their Indication For Use from January 1st, 2023, onwards.\n* No concurrent joint disease at the time of the surgery.\n* Absence of severe cognitive dysfunction demonstrated by 3 or more correct answers on the Pfeiffer test.\n* Ability to ambulate independently with or without walking aids before surgery.\n* Subject willingness to participate.\n\nExclusion Criteria:\n\n* Undisplaced or minimally displaced intracapsular hip fracture (Garden I-II).\n* Any Cephalic femoral head contraindication for use as reported in the current Instruction For Use.\n* Pathological fracture secondary to malignant disease.\n* Subjects with rheumatoid arthritis or symptomatic osteoarthritis.\n* Previous treatment to the same hip for a fracture at the time of the surgery.\n* Subjects who were deemed unsuitable for the surgical procedures by the anesthesiologist.\n* Severe cognitive dysfunction or cognitive impairment demonstrated by 2 or less correct answers on the Pfeiffer test.\n* Unable to walk before surgery (e.g., wheelchair or bed-ridden subjects).",{"count":132,"type":20},47,"Study design: monocentric, retrospective, observational and post-market clinical study.\n\nPurpose: To demonstrate the safety and performance of cephalic femoral heads. The eligible study population is represented by the entire population that underwent a hip replacement with cephalic femoral heads from 1st January 2023 onwards at the site in accordance with the indication for use of the product.",[135,24],"Hip Arthroplasty Replacement",[137,138],"femoral head","Partial hip arthroplasty","2025-03-13",{"date":141,"type":35},"2025-03-18",{"date":118,"type":20},{"date":144,"type":20},"2027-12",{"name":122,"class":123},{"id":147,"slug":148,"hasResults":11,"nctId":149,"briefTitle":150,"officialTitle":150,"acronym":4,"eligibilityCriteria":151,"healthyVolunteers":11,"sex":16,"minAge":152,"maxAge":4,"enrollmentInfo":153,"targetDuration":4,"studyType":21,"phases":4,"briefSummary":155,"conditions":156,"keywords":159,"overallStatus":59,"whyStopped":4,"lastUpdateSubmitDate":165,"lastUpdatePostDateStruct":166,"startDateStruct":168,"completionDateStruct":170,"leadSponsor":171,"locationsCount":4},"100570278","comparative-analysis-of-sarcopenia-in-rehabilitation-outcomes-following-femoral-neck-fracture-a-study-in-normal-weight-and-obese-study-cohort-100570278","NCT06705166","Comparative Analysis of Sarcopenia in Rehabilitation Outcomes Following Femoral Neck Fracture: a Study in Normal Weight and Obese Study Cohort","Inclusion Criteria:\n\n* Age between 60-85\n* Suffered a femoral neck fracture in the last year.\n* Subject willing and able to read, understand and sign an informed consent.\n\nExclusion Criteria:\n\n* Inability to comply with the study protocol or understand and sign an informed consent\n* Diagnosis of a psychiatric disorder prior to the recent femoral neck.\n* Active malignancy\n* History of other neurodegenerative diseases including Alzheimer's disease (AD), Parkinson's disease (PD), Lewy Body Dementia (LBD), Frontotemporal dementia (FTD), Multiple sclerosis (MS), Amyotrophic lateral sclerosis (ALS), Creutzfeld Jacob disease (CJD), Multisystem atrophy (MSA), Pseudobulbar palsy (PSP), Corticobasal degeneration (CBD), Wernicke Korsakoff syndrome\n* Chronic Inflammatory Disorders:(e.g., rheumatoid arthritis, systemic lupus erythematosus).\n* Endocrine Disorders: Individuals with endocrine disorders affecting muscle metabolism (e.g., Cushing's syndrome, hyperthyroidism)\n* Recent Major Surgeries: Participants who had undergone major surgeries other than femoral neck fracture within the last six months","60 Years",{"count":154,"type":20},300,"Impact of Obesity on Sarcopenia Prevalence and Severity in Elderly Adults Recovering from Femoral Neck Fractures: A Prospective Study\n\nIntroduction Age-related muscle loss, or sarcopenia, which includes reductions in both muscle mass and function, is increasingly recognized as a critical health issue in the elderly. Sarcopenia is associated with frailty, disability, and increased mortality. With its rising prevalence, obesity further complicates aging, leading to a condition termed \"sarcopenic obesity\" (SO), where sarcopenia coexists with obesity. This combination amplifies risks for physical disability, falls, and fractures in older adults. Although sarcopenia and obesity individually contribute to adverse health outcomes, their combined impact on recovery from hip fractures, particularly femoral neck fractures, is under-researched. Hip fractures severely impact the elderly, with over 40% failing to regain pre-fracture functionality and a mortality rate above 35% within three years post-fracture.\n\nThis study aims to assess the impact of obesity on sarcopenia prevalence and severity in older adults recovering from femoral neck fractures, addressing an essential gap in understanding SO's role in post-fracture rehabilitation outcomes.\n\nObjectives\n\n* To evaluate the prevalence and severity of sarcopenia among normal-weight versus obese elderly adults post-femoral neck fracture.\n* To investigate the association between sarcopenic obesity and functional recovery.\n* To determine whether obesity modifies sarcopenia's impact on rehabilitation outcomes.\n\nRisk-Benefit Statement The study entails minimal risk, as all procedures are non-invasive and consistent with routine rehabilitation practices. The potential benefits include enhanced understanding of sarcopenia's effect on hip fracture recovery, which may inform improved rehabilitation practices. Comprehensive health assessments may also benefit participants' post-fracture care.\n\nStudy Design Overview This prospective observational study includes hospitalized elderly patients undergoing rehabilitation post-femoral neck fracture. After obtaining informed consent, participants will complete an initial assessment, including demographic information, medical history, cognitive status, and anthropometric measurements. Blood samples will be collected for biochemical markers.\n\nStratification and Assessment:\n\nPatients will be categorized into normal-weight and obese groups. Comprehensive assessments, including cognitive function, mobility, frailty, muscle strength, and nutritional status, will establish a baseline for studying sarcopenia and obesity's impact on rehabilitation outcomes.\n\nPopulation and Criteria:\n\nSample Size: Up to 300 participants\n\nInclusion Criteria:\n\n* Age 60-85\n* Recent femoral neck fracture (within the past year)\n* Ability to provide informed consent\n\nExclusion Criteria:\n\n* Inability to comply with study requirements\n* History of neurodegenerative or psychiatric conditions, recent major surgeries (excluding femoral neck fracture), or conditions affecting muscle metabolism\n\nProcedures:\n\nBaseline Evaluation:\n\n* Cognitive Function: Mini-Mental State Examination (MMSE)\n* Anthropometric Measurements: BMI from height and weight\n* Functional Independence (FIM): Level of independence in daily activities\n* Mobility (Up \\& Go Test): Indicator of balance and mobility\n* Frailty and Muscle Strength: Handgrip strength, SARC-F questionnaire, Muscle Strength and Reflex Assessment (MSRA)\n* Nutritional Status: Mini Nutritional Assessment (MNA)\n* Laboratory Tests: CRP, calcium, vitamin D, CBC\n\nPost-Rehabilitation Evaluation:\n\nAfter rehabilitation, participants will repeat baseline assessments to determine changes in sarcopenia severity and functional status.\n\nUnscheduled Visits:\n\nParticipants may request evaluations outside the scheduled timeline, documented by the investigator as necessary.\n\nStatistical Analysis\n\n* Descriptive Analysis: Mean and standard deviations for continuous data, frequencies for categorical data.\n* Comparative Analysis: Independent t-tests to compare normal-weight and obese groups, dependent t-tests for within-group changes.\n* Univariate Analysis: Chi-square or Fisher's exact tests with a significance level of P \\\u003C 0.05.\n\nEthics and Confidentiality This study will adhere to the Declaration of Helsinki, ICH-GCP guidelines, and applicable regulations. Informed consent will be obtained from all participants, and confidentiality measures will protect patient privacy, with data limited to authorized personnel and anonymized in reports.\n\nInstitutional Review Board (IRB) Approval\n\nIRB approval will be obtained from the Israeli Ministry of Health, following ICH-GCP guidelines. The IRB will oversee the study protocol, consent forms, and all participant materials.\n\nData Storage and Study Termination\n\nData will be securely stored, with",[157,158,25,24],"Sarcopenia in Elderly","Sarcopenic Obesity",[160,161,162,163,164],"older adults","sarcopenia","obesity","rehabilitation","femoral fractures","2024-11-21",{"date":167,"type":35},"2024-11-26",{"date":169,"type":20},"2024-11-15",{"date":64,"type":20},{"name":172,"class":173},"Shmuel Harofeh Hospital, Geriatric Medical Center","OTHER_GOV"]