[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"fibromatosis\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:fibromatosis":27},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,1,0,[8],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":4,"eligibilityCriteria":15,"healthyVolunteers":16,"sex":17,"minAge":18,"maxAge":19,"enrollmentInfo":20,"targetDuration":4,"studyType":23,"phases":4,"briefSummary":24,"conditions":25,"keywords":4,"overallStatus":28,"whyStopped":4,"lastUpdateSubmitDate":29,"lastUpdatePostDateStruct":30,"startDateStruct":33,"completionDateStruct":35,"leadSponsor":37,"locationsCount":5},"100606820","prospective-clinical-trial-on-the-impact-of-uterine-firomatosis-on-pelvic-floor-100606820",false,"NCT07180524","Prospective Clinical Trial on the Impact of Uterine Firomatosis on Pelvic Floor.","Prospective Clinical Trial on the Impact of Uterine Fibromatosis Surgery on Pelvic Floor.","Inclusion Criteria:\n\n* Symptomatic uterine fibromatosis with intramural and\u002For subserosal myomas identified by ultrasound and topographically mapped\n* Patients with scheduled hysterectomy or myomectomy\n\nExclusion Criteria:\n\n* suspicion of malignant lesion.\n* active tumors\n* previous history of chemotherapy or radiotherapy\n* pregnancy\n* age \\\u003C18 years or \\>55 years (postmenopause)\n* history of pelvic static disorders prior to surgery",true,"FEMALE","35 Years","55 Years",{"count":21,"type":22},200,"ESTIMATED","OBSERVATIONAL","Uterine fibromatosis is one of the most frequent gynecological conditions; in fact, uterine fibroids involve approximately 25-30% of women during the fertile period. Risk factors for the development of this pathology include age, family history and ethnicity. Multiparity, advanced age for pregnancy and smoking appear to be protective factors.\n\nMyomas are responsible for numerous symptoms reported by patients, such as menometrorrhagia, pelvic pain and urinary and\u002For deficatory symptoms. Although myomas are asymptomatic in almost 50% of cases, they represent the first cause of hysterectomy for benign pathologies (about 2\u002F3 of cases). Urinary symptoms associated with myomas are rarely studied in patients with symptomatic uterine fibromatosis; therefore the impact that this pathology has on the symptoms related to pelvic-perineal dysfunction and what their prevalence is is not well known at present. The prevalence of urinary symptoms in women with uterine myomas is highly variable based on literature data and the studies considered; in fact, the most frequently reported urinary symptoms are urinary urgency (31-59%), dysuria (4-36%) and stress urinary incontinence (20-80%). Furthermore, there is currently no unanimous agreement between the topography and size of myomas and related urinary and pelvic symptoms.\n\nThe type of treatment varies from single or multiple myomectomy to hysterectomy performed laparoscopically or laparotomy. The choice of surgical approach depends on the number, size and position of myomas. To date, few studies have evaluated the impact of the type of surgical treatment on pelvic floor symptoms. In fact, although hysterectomy is considered a risk factor for the onset of pelvic floor disorders, removal of the uterus can sometimes improve urinary symptoms. However, some authors report, equally, a significant improvement in urinary symptoms after myomectomy. Further studies are needed to clarify the impact of myoma treatment on urinary symptoms.",[26,27],"Pelvic Floor Dysfunction","Fibromatosis","RECRUITING","2025-09-16",{"date":31,"type":32},"2025-09-18","ACTUAL",{"date":34,"type":32},"2024-06-30",{"date":36,"type":22},"2029-12-31",{"name":38,"class":39},"Fondazione IRCCS Policlinico San Matteo di Pavia","OTHER"]