[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"financial-hardship\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:financial-hardship":25},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,3,0,[8,47,76],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":13,"acronym":14,"eligibilityCriteria":15,"healthyVolunteers":16,"sex":17,"minAge":18,"maxAge":4,"enrollmentInfo":19,"targetDuration":4,"studyType":22,"phases":4,"briefSummary":23,"conditions":24,"keywords":28,"overallStatus":34,"whyStopped":4,"lastUpdateSubmitDate":35,"lastUpdatePostDateStruct":36,"startDateStruct":39,"completionDateStruct":41,"leadSponsor":43,"locationsCount":46},"100586961","development-of-measures-to-screen-for-financial-hardship-in-alzheimers-disease-and-dementia-100586961",false,"NCT06922188","Development of Measures to Screen for Financial Hardship in Alzheimer's Disease and Dementia","AD\u002FADRD","Inclusion Criteria:\n\n* Adults aged 18 years or older\n* One of the following:\n\n  * Clinical diagnosis of Alzheimer's disease or related dementia\n  * Being a caregiver to individuals with clinical diagnosis of Alzheimer's disease or related dementia\n* Able to read and speak English or Spanish\n* Able to provide informed consent\n* Residing in the United States\n\nExclusion Criteria:\n\n• Cognitive impairment precluding informed consent",true,"ALL","18 Years",{"count":20,"type":21},2460,"ESTIMATED","OBSERVATIONAL","Alzheimer's Disease and related dementias (AD\u002FADRD) are common and debilitating conditions. Financial hardship, a multidimensional construct of financial strain, financial stress and asset depletion, is common in AD\u002FADRD due to exorbitant out-of-pocket spending such as for long-term care, lower work productivity and income for their caregivers that can last for decades after disease onset, and difficulty deciding between nursing home care or home-based care while negotiating insurance coverage. People from historically marginalized groups can experience a double disparity with fewer financial resources to manage AD\u002FADRD and a greater risk of AD\u002FADRD. Screening for financial hardship in AD\u002FADRD is key for addressing the needs of patients and caregivers but critical barriers include a lack of suitable screening measures. Current measures are very general and meant for people without chronic medical conditions or are specific to other diseases. To fill this gap, this study will create a suite of measures that can screen for financial hardship in people with AD\u002FADRD and their families and caregivers. The measures will include a set to assess caregiver burden; a set to assess patient hardship as reported by the caregiver for patients who cannot report for themselves; and a set of patient-reported measures for patients that are able to report for themselves. To create these financial hardship screening measures, the project will conduct the following aims. Aim 1- Develop financial hardship screening measures for Alzheimer's Disease and related dementias: Using interviews with both caregivers and people with AD\u002FADRD, key indicators of financial hardship that are unique to AD\u002FADRD and the point in the lifespan in which it occurs will be identified. The ways that social and caregiver network size affect financial hardship will also be explored. Using the interviews and previous measures, preliminary measures will be created and will be reviewed by experts and a patient and caregiver advisory board. Aim 2- Create item response theory-based screening measures for financial hardship measures in Alzheimer's Disease and related dementias: Large samples of people with AD\u002FADRD (n=1000) and caregivers (n=1000) will be surveyed and item response theory will be used to evaluate and revise the measures and create scoring algorithms. A sample of additional caregivers matched to primary caregivers (n=400) will also be recruited to evaluate interrater reliability of the measures. Aim 3- Evaluate the financial hardship measures across patient and caregiver populations: Using the sample from Aim 2 and item response theory, we will evaluate the financial hardship screening measures across the following groups to ensure they are unbiased and reflect true differences: race\u002Fethnicity; patient comorbidities; stage of AD\u002FADRD; caregiver relationship; social network size; number of caregivers; financial support provided; and caregiver's own health status (disability, comorbidities). The resulting measures will improve identification of financial hardship in AD\u002FADRD.",[25,26,27],"Financial Hardship","Alzheimer's Disease (AD)","Alzheimer's Disease and Related Dementia (ADRD)",[29,30,31,32,33],"Social Determinants of Health","Financial Toxicity","Financial Burden","Dementia","Alzheimers Disease","RECRUITING","2026-02-18",{"date":37,"type":38},"2026-02-19","ACTUAL",{"date":40,"type":38},"2025-03-31",{"date":42,"type":21},"2029-12-18",{"name":44,"class":45},"Fred Hutchinson Cancer Center","OTHER",1,{"id":48,"slug":49,"hasResults":11,"nctId":50,"briefTitle":51,"officialTitle":52,"acronym":4,"eligibilityCriteria":53,"healthyVolunteers":11,"sex":17,"minAge":4,"maxAge":54,"enrollmentInfo":55,"targetDuration":4,"studyType":57,"phases":58,"briefSummary":60,"conditions":61,"keywords":65,"overallStatus":34,"whyStopped":4,"lastUpdateSubmitDate":66,"lastUpdatePostDateStruct":67,"startDateStruct":69,"completionDateStruct":71,"leadSponsor":73,"locationsCount":75},"100537855","pedirise-feasibility-100537855","NCT06283251","PediRISE Feasibility","Pilot Randomized Pediatric RISE (Resource Intervention to Support Equity) Feasibility Study","Inclusion Criteria\n\nCohort 1: Poverty-exposed children with cancer receiving front-line cancer-directed therapy\n\n1. Child diagnosed with de novo cancer\n2. Child has established care at a study site and initiated cancer directed therapy in the prior 2-months\n3. Child planned to receive at least 4-months of cancer-directed therapy at study site from time of diagnosis per initial cancer treatment plan\n4. Child is \\\u003C18 years at time of enrollment\n5. Parent\u002Fguardian screened positive for self-reported low-income (\\\u003C200% FPL)\n6. Family primary residence in CA, CT, MA, ME, NH, NJ, NY or RI\n7. Provider approval for permission to approach\n\nCohort 2: Poverty-exposed children with cancer undergoing HSCT\n\n1. Child undergoing allogeneic HSCT for treatment of cancer\n2. Child has established care at a study site and is between 30 days prior to start of planned conditioning through day +7 of HSCT at time of enrollment\n3. Child planned to receive follow-up care after discharge for HSCT at study site\n4. Child is \\\u003C18 years at the time of enrollment\n5. Parent\u002Fguardian screen positive for self-reported low-income (\\\u003C200% FPL)\n6. Family primary residence in CA, CT, MA, ME, NH, NJ, NY or RI\n7. Provider approval for permission to approach\n\nExclusion Criteria\n\nCohort 1: Poverty-exposed children with cancer receiving front-line cancer-directed therapy\n\n1. Planned transfer of child to a non-DFCI or non-Columbia facility for cancer-directed therapy\n2. Foreign national family receiving care as an Embassy-pay patient\n3. Child is enrolled on embedded correlative health equity aims of open or upcoming clinical drug trials which are powered on descriptive parent-reported poverty data (e.g. AALL1731, DFCI 25-001). Co-enrollment on a poverty intervention study would confound the specified endpoints of these open trial correlative studies\n4. Child or household member receiving SSI\n\nCohort 2: Poverty-exposed children with cancer undergoing HSCT\n\n1. Planned transfer of child to a non-DFCI, non-Columbia, or non UCSF facility for cancer-directed therapy\n2. Foreign national family receiving care as an Embassy-pay patient\n3. Child is enrolled on embedded correlative health equity aims of open or upcoming clinical drug trials which are powered on descriptive parent-reported poverty data (e.g. AALL1731, DFCI 25-001). Co-enrollment on a poverty intervention study would confound the specified endpoints of these open trial correlative studies\n4. Child previously received RISE intervention\n5. Child or household member receiving SSI","17 Years",{"count":56,"type":21},40,"INTERVENTIONAL",[59],"NA","The goal of this research study is to learn whether investigators can successfully give the PediRISE program to families-in other words, whether most families are interested in participating in a study about the PediRISE program, including a 50-50 chance of receiving standard usual care, and a 50-50 chance of receiving the PediRISE support program.\n\nThe names of the study groups in this research study are:\n\n* PediRISE Program Group\n* Usual Care Group",[62,63,25,64],"Pediatric Cancer","Financial Stress","Disparities",[62,63,25,64],"2026-02-09",{"date":68,"type":38},"2026-02-10",{"date":70,"type":38},"2024-05-15",{"date":72,"type":21},"2027-06-30",{"name":74,"class":45},"Dana-Farber Cancer Institute",4,{"id":77,"slug":78,"hasResults":11,"nctId":79,"briefTitle":80,"officialTitle":81,"acronym":4,"eligibilityCriteria":82,"healthyVolunteers":11,"sex":17,"minAge":4,"maxAge":4,"enrollmentInfo":83,"targetDuration":4,"studyType":57,"phases":84,"briefSummary":85,"conditions":86,"keywords":87,"overallStatus":90,"whyStopped":4,"lastUpdateSubmitDate":91,"lastUpdatePostDateStruct":92,"startDateStruct":94,"completionDateStruct":96,"leadSponsor":98,"locationsCount":46},"100553452","the-financial-navigator-program-100553452","NCT06486272","The Financial Navigator Program","The Financial Navigator Program - Optimizing Early Child Development by Facilitating Access to Financial Resources in the Neonatal Neurodevelopmental Follow-up Program","Inclusion Criteria:\n\n* Caregivers with a child followed in the NNFU in SickKids will be invited to participate in our study.\n* Caregiver needs to attend 4-month NNFU appointment.\n\nExclusion Criteria:\n\n* There are no exclusion criteria.",{"count":56,"type":21},[59],"Over one third of caregivers with a child admitted to the Hospital for Sick Children (SickKids) reported having difficulty making ends meet. The SickKids Medical-Financial Partnership (MFP) working group conducted in-depth interviews exploring financial needs and supports with selected caregivers in the Neonatal Neurodevelopmental Follow-up Program (NNFU). Results identified financial stress (including difficulties with employment, high cost of living, poverty, food insecurity, inaccessible supports, benefit time lines, costs of therapy) as a major theme. Caregivers generally supported the idea of hospital-based financial services. In this feasibility study we will trial a Financial Navigator Program in the NNFU.",[25],[88,89],"Financial Services","Neonatal Neurodevelopment Follow-up Clinic","NOT_YET_RECRUITING","2024-06-26",{"date":93,"type":38},"2024-07-03",{"date":95,"type":21},"2024-09",{"date":97,"type":21},"2026-09",{"name":99,"class":45},"The Hospital for Sick Children"]