[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"fissure-in-ano\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:fissure-in-ano":26},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,2,0,[8,44],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":4,"eligibilityCriteria":15,"healthyVolunteers":11,"sex":16,"minAge":17,"maxAge":4,"enrollmentInfo":18,"targetDuration":4,"studyType":21,"phases":22,"briefSummary":24,"conditions":25,"keywords":27,"overallStatus":31,"whyStopped":4,"lastUpdateSubmitDate":32,"lastUpdatePostDateStruct":33,"startDateStruct":36,"completionDateStruct":38,"leadSponsor":40,"locationsCount":43},"100408900","percutaneous-tibial-nerve-stimulation-ptns-for-the-treatment-of-chronic-anal-fissure-100408900",false,"NCT04604483","Percutaneous Tibial Nerve Stimulation (PTNS) for the Treatment of Chronic Anal Fissure","Percutaneous Tibial Nerve Stimulation for Chronic Anal Fissure - a Prospective Study","Inclusion Criteria:\n\n* Verified anal fissure (Clinical assessement by experienced proctological surgeon)\n* Full conservative treatment has been given\n\nExclusion Criteria:\n\n* Inflammatory bowel disease\n* Fistula and\u002For anal abscess\n* Patients with compromised immunity\n* Pregnancy\n* Treatment with anti-coagulants (not aspirin)\n* Previous irradiation towards pelvic floor\n* Pacemaker or implanted defibrillator","ALL","18 Years",{"count":19,"type":20},52,"ESTIMATED","INTERVENTIONAL",[23],"NA","Chronic anal fissure rarely heals spontaneously. About 50% heal on administration om topical muscle relaxants (e.g. diltiazem) and\u002For injection of Botulinum toxin, but for the remainder of patients surgery (with lateral internal sphincterotomy or fissurectomy) with subsequent risks of anal incontinence has been the golden standard. Treatment with PTNS (percutaneous tibial nerve stimulation) has been showed to produce healing of chronic anal fissures not responding to topical treatment, thus avoiding the risk for debilitating anal incontinence.",[26],"Fissure in Ano",[28,29,30],"Anal fissure","Percutaneous Tibial Nerve Stimulation","PTNS","NOT_YET_RECRUITING","2024-02-29",{"date":34,"type":35},"2024-03-01","ACTUAL",{"date":37,"type":20},"2024-10-01",{"date":39,"type":20},"2026-12",{"name":41,"class":42},"Region Skane","OTHER",1,{"id":45,"slug":46,"hasResults":11,"nctId":47,"briefTitle":48,"officialTitle":49,"acronym":4,"eligibilityCriteria":50,"healthyVolunteers":11,"sex":16,"minAge":17,"maxAge":51,"enrollmentInfo":52,"targetDuration":4,"studyType":21,"phases":54,"briefSummary":56,"conditions":57,"keywords":58,"overallStatus":69,"whyStopped":4,"lastUpdateSubmitDate":70,"lastUpdatePostDateStruct":71,"startDateStruct":73,"completionDateStruct":75,"leadSponsor":77,"locationsCount":80},"100351378","phase-4-complex-treatment-of-a-chronic-anal-fissure-100351378","NCT03855046","Complex Treatment of a Chronic Anal Fissure","A Comparative Efficacy and Safety Study of Lateral Subcutaneous Sphincterotomy and Botulinum Toxin Type A in the Treatment of Chronic Anal Fissure","Inclusion Criteria:\n\n* Patients with chronic anal fissure\n\nExclusion Criteria:\n\n* Inflammatory diseases of the colon\n* Pectenosis\n* Previous surgical interventions on the anal canal\n* IV grade internal and external hemorrhoids\n* Rectal fistula\n* Severe somatic diseases at the decompensation stage\n* Pregnancy and lactation\n* Individual intolerance and hypersensitivity to botulinum toxin\n* Myasthenia gravis and myasthenia-like syndromes\n* Anal sphincter insufficiency","70 Years",{"count":53,"type":20},340,[55],"PHASE4","This study is aimed at studying the efficacy and safety of treating chronic anal fissure with botulinum toxin versus lateral subcutaneous sphincterotomy.",[26],[59,28,60,61,62,63,64,65,66,67,68],"Internal sphincterotomy","Chronic anal fissure","botulinum toxin A","proctologic diseases","surgical treatment","Chronic anal pain","Fecal incontinence","Spasm of the internal sphincter","Anal sphincter insufficiency","randomized","RECRUITING","2022-01-26",{"date":72,"type":35},"2022-01-27",{"date":74,"type":35},"2019-09-01",{"date":76,"type":20},"2022-11-01",{"name":78,"class":79},"State Scientific Centre of Coloproctology, Russian Federation","OTHER_GOV",7]