[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"fitness-testing\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:fitness-testing":26},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,4,0,[8,54,81,106],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":13,"acronym":14,"eligibilityCriteria":15,"healthyVolunteers":16,"sex":17,"minAge":18,"maxAge":4,"enrollmentInfo":19,"targetDuration":4,"studyType":22,"phases":4,"briefSummary":23,"conditions":24,"keywords":31,"overallStatus":41,"whyStopped":4,"lastUpdateSubmitDate":42,"lastUpdatePostDateStruct":43,"startDateStruct":46,"completionDateStruct":48,"leadSponsor":50,"locationsCount":53},"100623223","molecular-indicators-of-systematic-fitness-100623223",false,"NCT07393841","Molecular Indicators of Systematic Fitness","MISFIT","Inclusion Criteria:\n\n* Be ≥18 years old\n* Be able to understand and provide informed consent (English; additional languages may be added via amendment with translated materials)\n* Be willing to complete VO₂max testing, blood draw, and questionnaires.\n* Be able to safely perform maximal\u002Fsymptom-limited exercise testing as determined by: PAR-Q+ screening and investigator review (included as an attachment) and resting vitals screening (heart rate)\n\nExclusion Criteria:\n\n* Conditions that, in the investigator's judgment, or a medical doctor, makes maximal exercise testing unsafe (e.g., unstable cardiovascular symptoms)\n* Contraindications or unwillingness to undergo venipuncture\n* Acute illness (fever, significant respiratory illness) at the time of testing\n* Failure to comply with procedures.",true,"ALL","18 Years",{"count":20,"type":21},250,"ESTIMATED","OBSERVATIONAL","The goal of this study is to characterize associations between cardiorespiratory fitness, as measured by VO₂max\u002FVO₂peak, and blood-based molecular measurements in adults. This is an observational study where research staff measures VO₂max\u002FVO₂peak and collects fasted, resting blood samples on the same day. The main questions it aims to answer are:\n\n1. Can a multi-analyte blood panel accurately predict directly measured VO₂max\u002FVO₂peak?\n2. How do these blood-based features vary across age, sex, and self-reported or documented physical activity profiles?\n3. Are the predictor analytes able to capture changes in VO₂max\u002FVO₂peak caused by a self-directed intervention (e.g., training for a marathon)?\n4. What is the analytic reliability of the predictor biomarkers?",[25,26,27,28,29,30],"Healthy Adult","Fitness Testing","Athlete","Aging","Exercise Physiology","Human Performance",[32,33,34,35,36,37,38,39,40],"VO2peak","VO2max","cardiorespiratory fitness","proteomics","blood biomarkers","cardiovascular health","oxygen transport","exercise performance","functional capacity","RECRUITING","2026-02-02",{"date":44,"type":45},"2026-02-06","ACTUAL",{"date":47,"type":45},"2026-01-05",{"date":49,"type":21},"2028-05-10",{"name":51,"class":52},"VO Health, Inc.","INDUSTRY",1,{"id":55,"slug":56,"hasResults":11,"nctId":57,"briefTitle":58,"officialTitle":59,"acronym":4,"eligibilityCriteria":60,"healthyVolunteers":16,"sex":17,"minAge":61,"maxAge":62,"enrollmentInfo":63,"targetDuration":4,"studyType":65,"phases":66,"briefSummary":68,"conditions":69,"keywords":4,"overallStatus":70,"whyStopped":4,"lastUpdateSubmitDate":71,"lastUpdatePostDateStruct":72,"startDateStruct":74,"completionDateStruct":76,"leadSponsor":78,"locationsCount":4},"100574363","exercise-effects-in-native-american-adolscents-100574363","NCT06758310","Exercise Effects in Native American Adolscents","Effects of an Individualized Exercise Program on Physical Performance Measures in Southwest Native American Adolescents","Inclusion Criteria:\n\n* Active members of the Gila River Indian Community (GRIC) with Native American ancestry\n* Ages 11-17\n\nExclusion Criteria:\n\n* Not active members of the GRIC or no Native American ancestry\n* Age \\\u003C11 or \\>17","11 Years","17 Years",{"count":64,"type":21},10,"INTERVENTIONAL",[67],"NA","This longitudinal study will investigate effects of exercise participation in Southwest Native American adolescents, ages 11-17, from the Gila River Indian Community. Vital signs, physical activity participation adherence, physical performance measures, and psychological\u002Fsocial measures will be assessed. Participants will attend one educational presentation for the initial session, explaining the benefits of physical exercise and expectations throughout the program. Baseline measurements for strength, flexibility, and cardiovascular fitness will be taken as well as height, weight and blood pressure. Based on individual performance measures, each participant will be provided a personalized exercise program to complete 3-4 times\u002Fweek for the duration for the duration of the study. Participants will also be provided an exercise journal to track their adherence to their exercise program each week. At the end of the session parents and adolescents separately will be asked to complete a written survey assessing physical, emotional, social, and school function. Physical performance measures will be taken every other week from the initial education and data collection session through 6 weeks.",[26],"NOT_YET_RECRUITING","2025-09-24",{"date":73,"type":45},"2025-09-25",{"date":75,"type":21},"2025-11-16",{"date":77,"type":21},"2025-12-20",{"name":79,"class":80},"Midwestern University","OTHER",{"id":82,"slug":83,"hasResults":11,"nctId":84,"briefTitle":85,"officialTitle":86,"acronym":4,"eligibilityCriteria":87,"healthyVolunteers":16,"sex":17,"minAge":88,"maxAge":4,"enrollmentInfo":89,"targetDuration":4,"studyType":22,"phases":4,"briefSummary":91,"conditions":92,"keywords":4,"overallStatus":41,"whyStopped":4,"lastUpdateSubmitDate":97,"lastUpdatePostDateStruct":98,"startDateStruct":100,"completionDateStruct":102,"leadSponsor":104,"locationsCount":53},"100596676","health-related-physical-fitness-and-executive-function-in-older-adults-a-prospective-study-100596676","NCT07048561","Health-related Physical Fitness and Executive Function in Older Adults: A Prospective Study","Changes in Health-related Physical Fitness on the Behavioural and Electrophysiological Aspects of Cool and Hot Executive Function in Older Adults: A Prospective Study","Inclusion Criteria:\n\n* Age 65 or above.\n* Able to engage in fitness testing.\n* Normal vision or corrected-to-normal vision.\n\nExclusion Criteria:\n\n* Suffering from cardiopulmonary-related diseases.\n* Suffering from cognitive, neurological or psychiatric disorders (e.g., dementia, Parkinson's disease, epilepsy, depression, schizophrenia, etc.).\n* Suffering from infectious diseases (e.g., hepatitis, human immunodeficiency virus or Creutzfeldt-Jakob disease).\n* Having a history of drug or alcohol abuse.\n* Having colour vision deficiency (e.g., colour blindness).\n* Having a family history of aneurysm.\n* Taking medications that affect brain function.","65 Years",{"count":90,"type":21},200,"This study aims to explore the relationship between health-related physical fitness and behavioural and electrophysiological aspects of cool and hot executive function in older adults through a year prospective study design. The main questions it aims to answer whether changes in health-related physical fitness will positively predict changes in behavioural and electrophysiological aspects of cool and hot executive functions in older adults. The participants will be asked to complete pre-test, a one-year observation period, and post-test. Both pre- and post-tests will measure health-related physical fitness, executive function, and various demographic variables and covariates. Health-related physical fitness assessments include cardiorespiratory endurance (YMCA submaximal cycle test), muscular strength (grip strength, chest press, and leg press), muscular endurance (30-second chair stand, 30-second bicep curl), flexibility (range of motion), and balance (Balance Error Scoring System). Executive function will be measured using the Stroop test and emotional Stroop test, with concurrent EEG recording of brain activity. Demographic variables and covariates include sex, age, years of education, annual income, Pittsburgh Sleep Quality Index (PSQI), International Physical Activity Questionnaire (IPAQ) Taiwan short form, World Health Organisation Quality of Life Brief Assessment (WHOQOL-BREF) Taiwan version, Geriatric Depression Scale, Mini-Mental State Examination (MMSE), digit span tests, and step count recorded by mobile phones or watches over the previous month, resting heart rate, and resting blood pressure. No interventions will be conducted during the one-year observation period, maintaining participants' normal daily living conditions.",[93,26,94,95,96],"Older Adults (65 Years and Older)","Executive Function (Cognition)","Prospective Study","Event-Related Potentials","2025-06-29",{"date":99,"type":45},"2025-07-02",{"date":101,"type":45},"2025-06-01",{"date":103,"type":21},"2027-03-31",{"name":105,"class":80},"National Taiwan Normal University",{"id":107,"slug":108,"hasResults":11,"nctId":109,"briefTitle":110,"officialTitle":111,"acronym":112,"eligibilityCriteria":113,"healthyVolunteers":11,"sex":17,"minAge":18,"maxAge":4,"enrollmentInfo":114,"targetDuration":4,"studyType":65,"phases":116,"briefSummary":117,"conditions":118,"keywords":122,"overallStatus":41,"whyStopped":4,"lastUpdateSubmitDate":127,"lastUpdatePostDateStruct":128,"startDateStruct":130,"completionDateStruct":132,"leadSponsor":134,"locationsCount":53},"100579382","anti-hypertensive-therapy-and-exercise-treatment-to-improve-vascular-health-in-patients-with-hypertension-100579382","NCT06823570","Anti-hypertensive Therapy and Exercise Treatment to Improve Vascular Health in Patients With Hypertension.","Anti-hypertensive Therapy and Exercise Treatment to Improve Vascular Health in Patients With Hypertension. A Randomized Controlled Trial.","Antitension","Inclusion Criteria:\n\n\\- systolic hypertension grade I-II (BP values \\>140 mmHg to \\\u003C180 mmHg) without anti-hypertensive medication treatment\n\nExclusion Criteria:\n\n* no written informed consent\n* age \\\u003C18 years\n* isolated diastolic hypertension\n* medical contraindications for the exercise treatment (for example orthopedic problems or an abnormal ECG during the cardio respiratory exercise test)\n* chronic eye diseases on both eyes (for example macular degeneration or glaucoma) or high intraocular pressure (\\>20 mmHg)",{"count":115,"type":21},60,[67],"This is a prospective, monocentric, randomized controlled trial to investigate the effect of anti-hypertensive treatment and\u002For individualized exercise training intervention on blood pressure and vascular health. Furthermore the investigators want to decipher mechanisms, which contribute to vascular health by analyzing changes in metabolism and cell function in relation to vascular reaction.",[119,120,26,121],"Hypertension","Vascular Function","Metabolism Changes",[34,123,124,125,126],"retinal microcirculation","endothelial function","exercise training","lifestyle treatment","2025-03-11",{"date":129,"type":45},"2025-03-12",{"date":131,"type":21},"2025-04-01",{"date":133,"type":21},"2028-12-31",{"name":135,"class":80},"Heinrich-Heine University, Duesseldorf"]