[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"flexor-tendon-rupture\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:flexor-tendon-rupture":28},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,4,0,[8,50,73,106],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":4,"eligibilityCriteria":15,"healthyVolunteers":11,"sex":16,"minAge":17,"maxAge":4,"enrollmentInfo":18,"targetDuration":4,"studyType":21,"phases":22,"briefSummary":24,"conditions":25,"keywords":30,"overallStatus":37,"whyStopped":4,"lastUpdateSubmitDate":38,"lastUpdatePostDateStruct":39,"startDateStruct":42,"completionDateStruct":44,"leadSponsor":46,"locationsCount":49},"100580365","registry-randomized-comparison-of-rehabilitation-regimens-after-flexor-tendon-injury-in-the-thumb-100580365",false,"NCT06836349","Registry-randomized Comparison of Rehabilitation Regimens After Flexor Tendon Injury in the Thumb","Registry-randomized Comparison of Rehabilitation Regimens After Flexor Pollicis Longus Injury in the Thumb","Inclusion Criteria:\n\nComplete laceration of the thumb flexor tendon (Flexor Pollicis Longus; FPL) within zone 1 and 2.\n\nAge over 15 years. Minors (\\\u003C18 years) are considered to have sufficient maturity to understand the implications of the research.\n\nSwedish-speaking \u002F able to understand spoken and written Swedish. Surgery performed within 14 days from the time of injury.\n\nExclusion Criteria:\n\nTendon injury with a defect requiring tendon grafting. Another complete tendon injury in the same hand. Extensive associated injuries, such as fracture, vascular injury with circulatory impairment, large skin defect, or preoperative signs of infection. Patient deemed unsuitable for early active motion therapy due to factors such as lack of cooperation, cognitive impairment, or substance abuse issues.\n\nPatient declines follow-up in the HAKIR quality registry. Wound infection making early active motion therapy inappropriate.","ALL","15 Years",{"count":19,"type":20},380,"ESTIMATED","INTERVENTIONAL",[23],"NA","Flexor tendon injuries in the thumb occur across all ages and genders. Each year, approximately 400 patients undergo surgery for a flexor tendon injury in Sweden. These injuries are exclusively treated at one of the seven specialized hand surgery clinics, as the surgery is technically demanding, and postoperative rehabilitation is critical, specialized, and requires expertise from hand therapists. To prevent tendon adhesions and stiffness in the thumb or fingers, controlled active motion therapy is usually initiated within a few days after surgery. Studies on finger flexor tendon injuries have shown that early active movement therapy leads to better mobility compared to immobilization. Consequently, early active training is now the standard treatment following flexor tendon repair. However, during postoperative rehabilitation, the repaired flexor tendon may rupture, often necessitating revision surgery.\n\nThe rupture rate after flexor tendon repair in the thumb is approximately three times higher than in other fingers (10% vs. 3%). While most studies on flexor tendon injuries focus on finger tendons, research on the outcomes of thumb flexor tendon injuries is limited. The biomechanics and anatomy of the thumb's flexor tendon differ significantly from those of finger tendons.\n\nThe objective of this study is to determine whether the rupture rate following thumb flexor tendon surgery can be reduced by immobilizing the thumb in a cast for four weeks postoperatively, compared to standard early active motion therapy, without negatively affecting joint mobility and thumb strength. Additionally, the study will evaluate patient-reported outcomes one year post-surgery for both rehabilitation regimens (immobilization vs. mobilization).\n\nThis study is a registry-randomized clinical trial (RRCT) involving five hand surgery clinics in Sweden. Data following randomization between the two rehabilitation protocols will be collected through follow-up in the Swedish National Hand Surgery Quality Registry (HAKIR).",[26,27,28,29],"Flexor Tendon Injury","Rehabilitation Program","Flexor Tendon Rupture","Thumb Injury",[31,32,33,34,35,36],"Flexor pollicis longus injury","RRCT","Early active motion","flexor tendon injury","Thumb","Immobilisation","RECRUITING","2026-05-31",{"date":40,"type":41},"2026-06-03","ACTUAL",{"date":43,"type":41},"2025-05-01",{"date":45,"type":20},"2031-12-31",{"name":47,"class":48},"Karolinska Institutet","OTHER",5,{"id":51,"slug":52,"hasResults":11,"nctId":53,"briefTitle":54,"officialTitle":54,"acronym":4,"eligibilityCriteria":55,"healthyVolunteers":11,"sex":16,"minAge":56,"maxAge":57,"enrollmentInfo":58,"targetDuration":4,"studyType":21,"phases":60,"briefSummary":61,"conditions":62,"keywords":4,"overallStatus":63,"whyStopped":4,"lastUpdateSubmitDate":64,"lastUpdatePostDateStruct":65,"startDateStruct":67,"completionDateStruct":68,"leadSponsor":70,"locationsCount":72},"100612597","effect-of-transfer-energy-capacitive-and-resistive-therapy-on-pain-and-range-of-motion-after-flexor-tendon-repair-100612597","NCT07255651","Effect of Transfer Energy Capacitive and Resistive Therapy on Pain and Range of Motion After Flexor Tendon Repair","Inclusion Criteria:\n\n* Ages of patients will be ranged from 20 to 35 years.\n* All patients underwent flexor tendon primary direct repair\n* All patients will be referred by a surgeon before starting the study procedure.\n\nExclusion Criteria:\n\n* Patient with digital nerve repairs.\n* Patients with associated vascular injuries requiring arterial repair.\n* Patients with associated crush injuries and soft tissue loss.\n* Patients with associated bone fractures.\n* Patients with associated extensor tendon injuries .\n* Patients with preexisting problems limiting joint motion.\n* Patients with diminished cognitive capacity.\n* Patients with history of previously failed repair.\n* Patients with allergic reactions to certain substances in the conductive cream\n* Patients with sensation impairment .","20 Years","35 Years",{"count":59,"type":20},40,[23],"The purpose of this study is to evaluate the impact of Transfer Energy Capacitive and Resistive therapy (TECAR) on pain and range of motion (ROM) after hand flexor tendon repair.",[28],"NOT_YET_RECRUITING","2025-11-20",{"date":66,"type":41},"2025-12-01",{"date":66,"type":20},{"date":69,"type":20},"2026-02-15",{"name":71,"class":48},"Cairo University",1,{"id":74,"slug":75,"hasResults":11,"nctId":76,"briefTitle":77,"officialTitle":78,"acronym":4,"eligibilityCriteria":79,"healthyVolunteers":11,"sex":16,"minAge":80,"maxAge":4,"enrollmentInfo":81,"targetDuration":4,"studyType":82,"phases":4,"briefSummary":83,"conditions":84,"keywords":88,"overallStatus":37,"whyStopped":4,"lastUpdateSubmitDate":97,"lastUpdatePostDateStruct":98,"startDateStruct":100,"completionDateStruct":102,"leadSponsor":104,"locationsCount":72},"100488666","medial-displacement-calcaneal-osteotomy-and-fdl--transfer---with-a-human-allogeneic-cortical-bone-screw-100488666","NCT05643079","Medial Displacement Calcaneal Osteotomy and FDL- Transfer - With a Human, Allogeneic Cortical Bone Screw","Medial Displacement Calcaneal Osteotomy and FDL- Transfer - a Prospective Comparative Study Between Metal\u002FBio-Tenodesis Screw (Arthrex) and the Human, Allogeneic Cortical Bone Screw (Shark Screw®️, Surgebright-GmbH)","Inclusion Criteria\n\n* Indication for the use of a metal\u002FBio-Tenodesis screw or human bone screw in medializing calcaneus osteotomy with FDL transfer.\n* BMI\\\u003C 40 kg\u002Fm²\n\nExclusion Criteria:\n\n* Insufficient knowledge of German\n* Alcohol and drug abuse\n* Pregnant woman or nursing mother\n* Foreseeable compliance problems\n* Neoplastic diseases, malignant bone tumors, rheumatoid arthritis\n* Active osteomyelitis\n* History of foot surgery\n* Advanced osteoarthritis of the lower ankle joint\n* Ulcerations in the skin of the surgical area\n* Immunosuppressive medications that cannot be discontinued\n* BMI \\>40","18 Years",{"count":59,"type":20},"OBSERVATIONAL","The goal of this observational study is to compare the use of a screw made of human bone (Shark-Screw®, Surgebright-GmbH) with the metal\u002FBio-Tenodesis screw (Arthrex) in the treatment of the symptomatic flatfoot using the medializing calcaneus osteotomy with flexor digitorum longus transfer (FDL) in adult patients. The advantage of the human bone screw is that after surgery no hardware removal is necessary. The screw is transformed from the body to normal bone.\n\nThe main questions it aims to answer are:\n\n* Can the human bone screw achieve union rates like the metal\u002FBio-Tenodesis screw?\n* Is the time to union similar between the different screws?\n* Is the complication rate similar between the different screws?\n* Are the activity scores American Orthopaedic Foot and Ankle Society (AOFAS), Foot and Ankle Outcome Score (FAOS) and Foot Function Index (FFI) after surgery similar in the compared patient groups?\n\nParticipants will have\n\n* the surgery\n* follow-ups at 6 weeks, 6 months, 1 and 2 years.\n* X-rays are performed at each follow up.\n* CT-scans are performed after 6 months.\n* activity scores are collected at the follow up after 6 months, 1 year and 2 years.",[85,28,86,87],"Flat Feet","Tibialis Posterior Dysfunction","Deformity, Foot",[89,90,91,92,93,94,95,96],"human allogeneic cortical bone screw","Shark Screw®","flat foot deformity","FDL Transfer","Tibialis posterior dysfunction","metal screw","Bio-Tenodesis screw","flat foot","2025-03-17",{"date":99,"type":41},"2025-03-20",{"date":101,"type":41},"2022-02-10",{"date":103,"type":20},"2028-02",{"name":105,"class":48},"Orthopedic Hospital Vienna Speising",{"id":107,"slug":108,"hasResults":11,"nctId":109,"briefTitle":110,"officialTitle":111,"acronym":4,"eligibilityCriteria":112,"healthyVolunteers":11,"sex":16,"minAge":113,"maxAge":114,"enrollmentInfo":115,"targetDuration":4,"studyType":21,"phases":117,"briefSummary":118,"conditions":119,"keywords":4,"overallStatus":37,"whyStopped":4,"lastUpdateSubmitDate":120,"lastUpdatePostDateStruct":121,"startDateStruct":123,"completionDateStruct":124,"leadSponsor":126,"locationsCount":128},"100548411","controlled-active-motion-vs-early-passive-mobilization-for-flexor-tendons-repair-100548411","NCT06420648","Controlled Active Motion vs Early Passive Mobilization for Flexor Tendons Repair","A Randomized Controlled Trial Comparing Controlled Active Motion and Early Passive Mobilization Protocols for Rehabilitation of Repaired Flexor Tendons in Zone II","Inclusion Criteria:\n\n* males or females\n* between 25-50 years\n* Post-surgical repair of the flexor digitorum profundus (FDP) and superficialis (FDS) tendons of a single-digit\n* the case should be recent (2-3 days post-surgical)\n\nExclusion Criteria:\n\n* age below 25 or above 50\n* a systemic disease affecting hand joints such as rheumatic arthritis\n* thumb flexor tendon repair will be excluded\n* chronic cases\n* concurrent injuries such as phalangeal fractures, joint injuries, or significant skin loss","25 Years","50 Years",{"count":116,"type":20},50,[23],"a randomized controlled trial tends to compare 2 rehabilitation approaches - early passive mobilization (EPM) and controlled active motion (CAM) - that are commonly used in the treatment of post-surgical flexor tendon repair of the hand",[28],"2024-06-04",{"date":122,"type":41},"2024-06-06",{"date":120,"type":41},{"date":125,"type":20},"2024-12-30",{"name":127,"class":48},"University of Hail",2]