[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"fluoride\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:fluoride":29},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,1,0,[8],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":4,"eligibilityCriteria":15,"healthyVolunteers":16,"sex":17,"minAge":18,"maxAge":19,"enrollmentInfo":20,"targetDuration":4,"studyType":23,"phases":24,"briefSummary":26,"conditions":27,"keywords":4,"overallStatus":31,"whyStopped":4,"lastUpdateSubmitDate":32,"lastUpdatePostDateStruct":33,"startDateStruct":36,"completionDateStruct":38,"leadSponsor":40,"locationsCount":4},"100554008","phase-1-efficacy-of-formulated-eggshell-derived-nano-hydroxyapatite-containing-toothpaste-with-and-without-addition-of-fluoride-vs-conventional-desensitizing-fluoride-containing-toothpaste-in-management-of-dentin-hypersensitivity-100554008",false,"NCT06493500","Efficacy of Formulated Eggshell Derived Nano-hydroxyapatite Containing Toothpaste With and Without Addition of Fluoride vs. Conventional Desensitizing Fluoride Containing Toothpaste in Management of Dentin Hypersensitivity","Efficacy of Nano-hydroxyapatite Containing Tooth Paste on Dentin Hypersensitivity of Adult Patient","Inclusion Criteria:\n\n* Adult Patients Aged 18-60\n* Males or females.\n* Good oral hygiene\n* Absence of abnormal occlusion habits (e.g. bruxism, nail biting, tooth clenching and mouth breathing).\n* Teeth with hypersensitivity, VAS ≥5\n* Co-operative patients who show interest to participate in the study.\n\nExclusion Criteria:\n\n* Patients with known allergic or adverse reaction to the tested materials.\n* Systematic disease that may affect participation.\n* Xerostomic patients.\n* Patients with bad oral hygiene\n* Patients with orthodontic appliances, or bridge work that might interfere with evaluation\n* Patients who did any periodontal surgeries within the previous 6 months.\n* Patients with physical disabilities",true,"ALL","18 Years","60 Years",{"count":21,"type":22},39,"ESTIMATED","INTERVENTIONAL",[25],"PHASE1","compare the effectiveness of Eggshell derived nano-Hydroxyapatite with and without fluoride and conventional fluoride containing tooth paste versus conventional desensitizing fluoride containing tooth paste on dentinal tubule occlusion and dentin mineral deposition.",[28,29,30],"Dentin Hypersensitivity","Fluoride","Nano-hydroxy Apatite","NOT_YET_RECRUITING","2024-07-06",{"date":34,"type":35},"2024-07-10","ACTUAL",{"date":37,"type":22},"2024-07",{"date":39,"type":22},"2025-03",{"name":41,"class":42},"Cairo University","OTHER"]