[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"focus-is-on-healthy-subjects\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:focus-is-on-healthy-subjects":29},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,1,0,[8],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":15,"eligibilityCriteria":16,"healthyVolunteers":17,"sex":18,"minAge":19,"maxAge":20,"enrollmentInfo":21,"targetDuration":4,"studyType":24,"phases":25,"briefSummary":27,"conditions":28,"keywords":30,"overallStatus":33,"whyStopped":4,"lastUpdateSubmitDate":34,"lastUpdatePostDateStruct":35,"startDateStruct":38,"completionDateStruct":40,"leadSponsor":42,"locationsCount":5},"100611867","phase-2-vaginal-detection-of-orally-delivered-probiotic-strains-in-healthy-women-100611867",false,"NCT07246161","Vaginal Detection of Orally Delivered Probiotic Strains in Healthy Women","Detection of Orally Delivered Probiotic Strains in the Vaginal Microbiome of Healthy Female Adults","VSS2","Inclusion Criteria:\n\n* Clinically healthy female between the ages of 18 and 50 years, inclusive,\n* have a regular or predictable menstrual cycle\n* Typically have regular bowel movements,\n* Willing and able to consume a probiotic supplement for 4 weeks,\n* Willing to discontinue consumption of probiotic supplement and probiotic-fortified products 2 weeks before the start of the study and throughout the study,\n* Willing to discontinue fiber supplements 2 weeks before the start of the study, and throughout the study,\n* Willing to provide 1 stool sample 4 times throughout the study,\n* Willing to provide 2 vaginal swabs 4 times throughout the study,\n* Willing to undergo vaginal pH swab measurements (with a swab) 5 times throughout the study,\n* Willing to provide 2 perineal skin swabs (skin between the vagina and the anus) 3 times throughout the study,\n* Willing to complete a pregnancy test at the screening visit.\n\nExclusion Criteria:\n\n* Menopausal women,\n* Vaginal pH \\\u003C 2 or \\> 5 measured at screening,\n\n  •. Menstruation during the sample collection times,\n* Women that are lactating, pregnant, attempting to get pregnant, or have a positive pregnancy test,\n* Use of vaginal probiotics in the last 3 months,\n* Use of local vaginal antibiotics or antifungals in the last 3 months.\n* Use of oral antibiotics or antifungals in the last month,\n* Ongoing symptoms of vaginal and\u002For urinary tract infections,\n* Current treatment for vaginal sepsis or urosepsis,\n* Currently being treated for a severe chronic disease (e.g. cancer, renal failure, chronic inflammatory digestive or gastro-intestinal disease, immunodeficiency, etc.),\n* Clinical diagnosis of a gynecological disease or condition (e.g, fibroma, endometriosis, polycystic ovarian syndrome, etc.),\n* Clinical diagnosis of secondary dysmenorrhea,\n* Intolerance, allergy or sensitivity to milk, soy, or yeast.",true,"FEMALE","18 Years","50 Years",{"count":22,"type":23},72,"ESTIMATED","INTERVENTIONAL",[26],"PHASE2","The purpose of the present study is to obtain more information on the transit of orally ingested probiotics to the vagina.",[29],"Focus is on Healthy Subjects",[31,32],"Probiotics","Women's Health","RECRUITING","2026-06-16",{"date":36,"type":37},"2026-06-18","ACTUAL",{"date":39,"type":37},"2025-10-20",{"date":41,"type":23},"2026-10",{"name":43,"class":44},"Lallemand Health Solutions","INDUSTRY"]