[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"follicular-lymphoma-gastric-or-duodenal\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:follicular-lymphoma-gastric-or-duodenal":26},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,1,0,[8],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":4,"eligibilityCriteria":15,"healthyVolunteers":11,"sex":16,"minAge":17,"maxAge":4,"enrollmentInfo":18,"targetDuration":4,"studyType":21,"phases":22,"briefSummary":24,"conditions":25,"keywords":28,"overallStatus":40,"whyStopped":4,"lastUpdateSubmitDate":41,"lastUpdatePostDateStruct":42,"startDateStruct":45,"completionDateStruct":47,"leadSponsor":49,"locationsCount":5},"100369955","isrt-20-gy-for-indolent-localized-gastrointestinal-gi-lymphoma-100369955",false,"NCT04097067","ISRT 20 Gy for Indolent Localized Gastrointestinal (GI)-Lymphoma","Phase II Trial to Assess the Efficacy of Low Radiation Dose of 20 Gy for the Treatment of Marginal Zone Lymphoma or Follicular Lymphoma Stage I-II Localized in the Stomach or the Duodenum","Inclusion Criteria:\n\n* primary indolent gastric or duodenal lymphoma\n* pathology: marginal zone lymphoma (MZL) or follicular lymphoma (FL)\n* stage: clinical stage I or II (Ann Arbor classification)\n* H. pylori negative or antibiotic resistant lymphoma\n* IPI or FLIPI score low - high (0-4)\n* any size of tumor or affected lymph nodes\n* male or female with age ≥ 18 years\n* performance status ECOG 0 - 3\n* written informed consent by the patient\n\nExclusion Criteria:\n\n* prior radiation treatment of the gastrointestinal lymphoma\n* stage: clinical stage III or IV (Ann Arbor classification)-unability to understand the informed consent or unwillingness to participate in the study\n* severe comorbidity or organ dysfunction contraindicating the use of RT (liver cirrhosis Child-Pugh C, chronic obstructive pulmonary disease GOLD 4, heart insufficiency NYHA IV, dialysis dependent renal insufficiency, uncontrolled epilepsy)\n* known seropositivity for HIV\n* acute hepatitis B or C infection\n* chronic inflammatory bowel disease\n* prior malignant disease (exclusion: basalioma, non-metastasized solid tumor in constant remission diagnosed \\>3 years ago)\n* pregnancy or breastfeeding\n* active substance abuse or severely compromised compliance","ALL","18 Years",{"count":19,"type":20},83,"ESTIMATED","INTERVENTIONAL",[23],"NA","This trial studies the effectivity of low-dose radiation therapy with 10x2Gy for the treatment of patients with stage I-II stomach or duodenal Lymphoma (Marginal Zone or Follicular)",[26,27],"Follicular Lymphoma (Gastric or Duodenal)","Marginal Zone Lymphoma (Gastric or Duodenal)",[29,30,31,32,33,34,35,36,37,38,39],"Lymphoma","Lymphoma, B-Cell, Marginal Zone","Neoplasms by Histologic Type","Neoplasms","Lymphoproliferative Disorders","Lymphatic Diseases","Immunoproliferative Disorders","Immune System Diseases","Lymphoma, B-Cell","Lymphoma, Non-Hodgkin","Lymphoma, follicular","RECRUITING","2024-08-26",{"date":43,"type":44},"2024-08-27","ACTUAL",{"date":46,"type":44},"2019-09-01",{"date":48,"type":20},"2025-08-31",{"name":50,"class":51},"University Hospital Muenster","OTHER"]