[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"food-intake-measurement\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:food-intake-measurement":32},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,2,0,[8,53],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":15,"eligibilityCriteria":16,"healthyVolunteers":17,"sex":18,"minAge":19,"maxAge":20,"enrollmentInfo":21,"targetDuration":4,"studyType":24,"phases":25,"briefSummary":27,"conditions":28,"keywords":33,"overallStatus":40,"whyStopped":4,"lastUpdateSubmitDate":41,"lastUpdatePostDateStruct":42,"startDateStruct":45,"completionDateStruct":47,"leadSponsor":49,"locationsCount":52},"100626622","energy-reduction-and-umami-100626622",false,"NCT07438028","Energy Reduction and Umami","Interactive Effects of Umami Taste Intensity and Energy Density on Longer Term Food Intake","Season","Inclusion Criteria:\n\n* Healthy: as judged by the participant;\n* Age 16-65 years at the time of inclusion, assessed by date of birth;\n* Proper understanding of the Dutch language, as questionnaires will be in Dutch;\n* Able to visit Wageningen University, as required for dietary intervention and testing;\n* Body mass index 20-30 kg\u002Fm2;\n* Having normal taste ability, assessed using Mueller taste strip test, ≥12 out of 20 assessed correctly.\n\nExclusion Criteria:\n\n* Suffering from endocrine- or gastro-intestinal diseases or other diseases that might influence study outcomes (such as diabetes, Crohn's disease, cardiovascular disease, hypertension, etc.);\n* Diagnosed with eating disorders (currently or in the past);\n* Diagnosed with taste or smell disorders in the past six months;\n* Pregnant or lactating during the study intervention;\n* Following a strict dietary regime;\n* Extreme physical activity (\\>10 hours per week moderate\u002Fhigh intensity exercise);\n* Gain or loss of more than 5 kgs in the last six months prior to study entry;\n* Suffering from lack of appetite for any reason;\n* Use of medication that may influence the appetite (medication will be judged by the medical investigator);\n* Having a food allergy and\u002For intolerance for foods used in the dietary intervention (e.g. lactose intolerance, gluten intolerance, MSG sensitivity). This will be assessed with an open question;\n* Consumes more than 14 (women) or 21 (men) glasses of alcohol per week;\n* Consumes MSG-rich sauces (soy sauce, ketjap and\u002For curry paste) more than once per day, or consumes more than 3 savoury food items (paprika chips, instant noodles, sundried tomatoes and\u002For pre-packaged seasonings) per day. This will be assessed with a frequency of consumption table;\n* Irregular eating pattern. This will be measured with a frequency of meal\u002Ffood consumption table, and is defined as: frequency of breakfast consumption less than once per week;\n* Unwilling to maintain regular exercise pattern during the study period. This will be assessed with a yes\u002Fno question;\n* Unwilling to quit use of soft or hard drugs during the intervention;\n* Student or personnel of the division of Human Nutrition and Health, Wageningen University;\n* Participating in any other intervention study\u002Fstudies or planning to participate in another intervention study during the study period.",true,"ALL","18 Years","65 Years",{"count":22,"type":23},30,"ESTIMATED","INTERVENTIONAL",[26],"NA","People tend to regulate intake by the weight of food rather than its energy content, making energy dense foods, especially those combining salty, fatty, and umami tastes, more likely to promote passive overconsumption. Lowering energy density can reduce daily energy intake, but often decreases palatability, whereas umami can enhance palatability, and sometimes decrease food intake. This suggests that adding umami to a regular energy dense diet could reduce food intake over time, and that adding umami to a reduced energy dense diet could sustain palatability and limit compensatory energy intake. Therefore, the aim of this study is to assess the effect of a 2-week dietary intervention of adding umami and\u002For lowering energy density on food intake. Secondary objectives are whether adding umami and\u002For lowering energy density affect dietary satisfaction, appetite, perceived umami intensity, food preferences, bodyweight and composition, and wellbeing ratings.\n\nThis will assessed in a double-blind crossover, randomized controlled trial of three times two weeks, each separated by two weeks washout in 33 healthy Dutch adults between 18-65 years of age, with a BMI between 20-30. Umami taste will be added through MSG supplementation of the three main meals. Supplementation will depend on both intervention group, and individual participants' body weight. Energy density will be lowered by swapping regular products for low-fat, low-sugar or higher water products.\n\nThe three intervention diets will vary in umami taste intensity, and\u002For energy density: 1) regular energy density without added umami (control), 2) regular energy density with added umami, 3) reduced energy density with added umami. Umami will be supplemented by supplementing food items with 55-60 mg MSG per kg bodyweight daily, divided over three eating occasions. Foods will be offered ad libitum, and participants will add a seasoning sachet containing MSG to their selected portion.\n\nThe primary objective will be to compare average daily food intake (kcal) over two weeks between the three dietary interventions differing in umami taste intensity and energy density. Secondary outcomes are dietary satisfaction, appetite, perceived umami intensity, food preferences, bodyweight and composition, and wellbeing ratings.",[29,30,31,32],"Sensory Testing","Umami Taste","Energy Density","Food Intake Measurement",[34,35,36,37,38,39],"umami","taste","intensity","ad libitum","intake","reduced energy","NOT_YET_RECRUITING","2026-05-22",{"date":43,"type":44},"2026-05-27","ACTUAL",{"date":46,"type":23},"2026-09",{"date":48,"type":23},"2026-12",{"name":50,"class":51},"Wageningen University","OTHER",1,{"id":54,"slug":55,"hasResults":11,"nctId":56,"briefTitle":57,"officialTitle":58,"acronym":59,"eligibilityCriteria":60,"healthyVolunteers":17,"sex":18,"minAge":19,"maxAge":4,"enrollmentInfo":61,"targetDuration":4,"studyType":63,"phases":4,"briefSummary":64,"conditions":65,"keywords":67,"overallStatus":72,"whyStopped":4,"lastUpdateSubmitDate":73,"lastUpdatePostDateStruct":74,"startDateStruct":76,"completionDateStruct":78,"leadSponsor":80,"locationsCount":82},"100583688","identifying-the-best-tools-for-recording-diet-in-free-living-uk-adults-sodiat-2-study-100583688","NCT06879574","Identifying the Best Tools for Recording Diet in Free-living UK Adults (SODIAT-2 Study)","Investigating a Data-driven Standardized and Objective Dietary Intake Assessment Tool in Free-living Individuals - SODIAT-2 Study","SODIAT-2","Inclusion Criteria:\n\n* 18 years and older\n* Lives in Great Britain (England, Schotland and Walse)\n* Able to read\u002Funderstand instructions written in English and are fluent in English\n\nExclusion Criteria:\n\n* Diagnosed or self-report as being underweight (have a body mass index (BMI) of less than 18.5 kg\u002Fm2)\n* Are unwilling\u002Funable to collect urine and blood samples, use the wearable camera as instructed and\u002For spend 20-30 min online recording what they've recently had to eat\u002Fdrink on multiple occasions\n* Are unwilling\u002Funable to have a video call with a researcher with cameras turned on\n* Are unwilling\u002Funable to post samples on specific days and receive\u002Fsend a larger parcel at the start\u002Fend of the study (note: all return packaging and postage will be provided by us and will include a courier delivery and collection)\n* Are unwilling\u002Funable to receive a single grocery delivery from Sainsbury's or Tesco online supermarkets (delivery to be arranged by us), includes living in a postcode area that cannot receive grocery deliveries from Tesco or Sainsburys as well as not having space to refrigerate and freeze items.\n* Are unwilling\u002Funable to eat\u002Fdrink any items on the calibration menu, e.g., food allergies\u002Fintolerances, dislike of food items, unable eat (e.g. vegan or have to avoid for a medical condition) or cannot eat 3 meals plus snacks daily (note: vegetarians can take part)\n* Are unwilling\u002Funable to avoid taking dietary and herbal supplements for at least 1 week before and during the 5-week study (e.g. fish oils, vitamins, iron, protein shakes, nutrient powders, joint care)\n* Are pregnant, may be pregnant or breast-feeding\n* Currently experiencing, recovering or at a high risk of an eating disorder (e.g., previous diagnosis, or concerns that you have an unhealthy relationship with food)\n* Have a health condition, are taking medication and\u002For undergoing medical treatment that affects metabolism, appetite and\u002For ability to eat the calibration menu (e.g. cancer, chemotherapy, diabetes, gastrointestinal disorders (such as inflammatory bowel disease, Crohn's disease), kidney disease, liver disease, HIV or AIDS)\n* Are taking any of the following medications: androgens, blood thinners, phenytoin, erythromycin, or thyroid hormones\n* Long-term use of any of the following medications: anti-inflammatories (NSAIDS), steroids\u002Fcorticosteroids or antibiotics (eligible following a 4-week washout after short term use; eligible if use is infrequent)\n* Use illicit substances\u002Frecreational drugs\n* Have been diagnosed with dementia or other conditions affecting memory\n* Do not have anyone at home, work, etc. to help them if they require assistance to use the study tools (such as arthritis, Parkinson's disease, sight loss, etc.)\n\nIf the participants have recently taken part in another intervention study, a 4-week washout will be required before they are able to start the study.",{"count":62,"type":23},133,"OBSERVATIONAL","The aim of the SODIAT-2 study is to evaluate the effectiveness of dietary intake assessment tools in a real-world setting. These tools include wearable cameras, spot urine samples, capillary blood samples, and a web-based food frequency questionnaire (FFQ). The main questions it aims to answer are:\n\nIs the accuracy of dietary assessment improved in free-living environments when a combination of subjective and objective assessments tools are used?\n\nSecondary research questions are:\n\nCan wearable cameras accurately monitor the daily dietary intake of free-living individuals? Does a combination of capillary blood samples and spot urine samples provide a robust assessment of the nutrient status and habitual dietary exposure in a free-living setting? Can data-driven integration of multiple emerging technologies create a dietary assessment tool that is low burden, accurate and scalable in free-living populations? Can a condensed FFQ estimate diet quality as effectively as a detailed FFQ?\n\nParticipants will:\n\nUse the dietary assessment tools (wearable camera, spot urine, capillary blood, and eNutri FFQ web-app) as instructed over a 5-week period from their home and\u002For working space.\n\nTake part in two monitoring weeks (week 1 and week 5) where they will record their usual dietary intake over 3 days.\n\nConsume an identical 3-day study meal plan during the test (calibration) diet week 3, whilst repeating the monitoring week measurements.\n\nThis study aims to recruit 133 adults living in Great Britain (GB) to better understand how these tools perform outside of a clinical environment.",[66,32],"Dietary Intake Assessment",[68,69,70,71],"Nutrition","Health","Dietary reporting","Misreporting","RECRUITING","2025-11-21",{"date":75,"type":44},"2025-11-28",{"date":77,"type":44},"2025-08-25",{"date":79,"type":23},"2026-07",{"name":81,"class":51},"University of Reading",4]