[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"foot-drop\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:foot-drop":28},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,6,0,[8,47,75,103,126,151],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":4,"eligibilityCriteria":15,"healthyVolunteers":11,"sex":16,"minAge":17,"maxAge":18,"enrollmentInfo":19,"targetDuration":4,"studyType":22,"phases":23,"briefSummary":25,"conditions":26,"keywords":30,"overallStatus":34,"whyStopped":4,"lastUpdateSubmitDate":35,"lastUpdatePostDateStruct":36,"startDateStruct":39,"completionDateStruct":41,"leadSponsor":43,"locationsCount":46},"100434258","enms-with-balance-feedback-for-post-stroke-ankle-foot-rehabilitation-100434258",false,"NCT04934787","ENMS With Balance Feedback for Post-stroke Ankle-foot Rehabilitation","Exo-neuro-musculo-skeleton With Balance Sensing Feedback for Ankle-foot Rehabilitation After Stroke","Inclusion Criteria:\n\n* At least 6 months after the onset of stroke\n* Have sufficient cognition to follow simple instructions, as well as understand the content and purpose of the experiment (Mini-Mental State Examination (MMSE) score \\>21).\n* Have mild-to-moderate motor impairment in the affected lower limb with foot drop but be capable of standing and walking without manual assistance.\n* Fugl-Meyer Assessment (FMA), total score on the lower limb \\\u003C20\n* Functional Ambulatory Category (FAC) ≥4\n* Berg Balance Scale (BBS) ≥40\n\nExclusion Criteria:\n\n* The exclusion criteria will be server spasticity at the ankle joint measured by Modified Ashworth Score (MAS) \\>3.\n* Receiving other lower limb rehabilitative interventions at the same time","ALL","18 Years","70 Years",{"count":20,"type":21},60,"ESTIMATED","INTERVENTIONAL",[24],"NA","In this work, a novel hybrid ankle-foot robot is designed for gait rehabilitation after stroke, i.e., exoneuromusculoskeleton with balance sensing feedback (ENMS-BSF) by integrating the advantages of soft pneumatic muscle, functional electrical stimulation, exoskeleton and foot balance feedback in one system. With the assistance of the ENMS-BSF the foot drop and foot inversion could be corrected with improved muscle coordination in the paretic lower limb. The device is wearable and light-in-weight for unilateral application during walking. It is hypothesized that with the intervention of the ENMS-BSF the gait pattern of persons after stroke can be improved with long-term rehabilitative effects.",[27,28,29],"Cerebrovascular Stroke","Foot Drop","Foot Inversion Deformity",[31,32,33],"Robot","Stroke","Lower limb","RECRUITING","2026-06-18",{"date":37,"type":38},"2026-06-22","ACTUAL",{"date":40,"type":38},"2021-07-01",{"date":42,"type":21},"2027-12-31",{"name":44,"class":45},"The Hong Kong Polytechnic University","OTHER",1,{"id":48,"slug":49,"hasResults":11,"nctId":50,"briefTitle":51,"officialTitle":52,"acronym":53,"eligibilityCriteria":54,"healthyVolunteers":11,"sex":16,"minAge":17,"maxAge":4,"enrollmentInfo":55,"targetDuration":4,"studyType":22,"phases":57,"briefSummary":58,"conditions":59,"keywords":62,"overallStatus":34,"whyStopped":4,"lastUpdateSubmitDate":66,"lastUpdatePostDateStruct":67,"startDateStruct":69,"completionDateStruct":71,"leadSponsor":73,"locationsCount":46},"100637837","combined-functional-electrical-and-transcranial-direct-current-stimulation-for-foot-drop-100637837","NCT07592221","Combined Functional Electrical and Transcranial Direct Current Stimulation for Foot Drop","Combined Functional Electrical and Transcranial Direct Current Stimulation for Foot Drop: A Case Series","tDCS","Inclusion Criteria: To participate, you must be:\n\n* 18 years or older\n* Have had 1 or more strokes (\\> 6 months) affecting ankle dorsiflexion.\n* Discharged from all rehabilitative services.\n* Can walk independently with\u002Fwithout using an assistive device such as a cane without an ankle-foot orthosis (AFO) for 15 minutes.\n\nExclusion Criteria: You must not have:\n\n* An inability to repeat and understand 2-step commands.\n* Peripheral neuropathy\n* Damage to the skull or scalp, such as a fracture History of seizures or epilepsy Extremely high or low blood pressure or heart rate Chest pain or shortness of breath when you are resting Botox injections to your leg or foot in the last 4 months",{"count":56,"type":21},30,[24],"This study aims to determine if combining the treatments of transcranial direct current stimulation (tDCS) and functional electrical stimulation (FES) will better help persons with stroke who have difficulty lifting their toes. As part of the treatment, subjects will receive electrical stimulation through pads on their scalp (similar to what one may have received in physical therapy previously to an arm or leg). This protocol is called transcranial direct current stimulation (tDCS). Subjects will also receive electrical stimulation through pads on their leg. This is called functional electrical stimulation (FES). During treatment sessions, subjects will also perform leg activity\u002Fstrengthening exercises. The aim is to evaluate whether combining FES and tDCS within a PT session would reduce foot drop as indicated by improvements in the amount of toe clearance and ankle motion persons with stroke.",[60,28,61],"Falls","Post Stroke Recovery",[63,64,65],"transcranial direct current stimulation","functional electrical stimulation","minimum toe clearance","2026-05-11",{"date":68,"type":38},"2026-05-18",{"date":70,"type":21},"2026-06-01",{"date":72,"type":21},"2029-08-30",{"name":74,"class":45},"Saint Joseph's University, Philadelphia",{"id":76,"slug":77,"hasResults":11,"nctId":78,"briefTitle":79,"officialTitle":80,"acronym":4,"eligibilityCriteria":81,"healthyVolunteers":11,"sex":16,"minAge":17,"maxAge":4,"enrollmentInfo":82,"targetDuration":4,"studyType":22,"phases":84,"briefSummary":85,"conditions":86,"keywords":87,"overallStatus":93,"whyStopped":4,"lastUpdateSubmitDate":94,"lastUpdatePostDateStruct":95,"startDateStruct":97,"completionDateStruct":99,"leadSponsor":101,"locationsCount":46},"100586113","innovative-shoe-for-people-with-foot-drop-100586113","NCT06911151","Innovative Shoe for People With Foot Drop","Innovative Footwear for People Experiencing Foot Drop; a Feasibility Study","Inclusion Criteria:\n\n* Individuals aged 18+ years\n* Individuals experiencing foot drop as diagnosed by a health professional due to any health condition for 6 months or more\n* the ability to walk at least 6 metres (with or without walking aid) at their own pace\n* with capacity to consent\n* Those with English as a 2nd language may bring a translator.\n\nExclusion Criteria:\n\n* impaired cognitive function (as assessed in the initial phone call using elements of the Abbreviated Mental Test Score27) and questions that will assess the potential participant's understanding of the research protocol);\n* inability to achieve minimum 10 degrees ankle flexion;\n* lymphoedema of lower limbs\u002F deep vein thrombosis in the last 6 months;\n* any change in medication\u002Ftreatment in the last 3 months that may cause a change in walking experience;\n* existing pressure areas at risk of, or active skin breakdown in areas that will make contact with the inner of the shoe.",{"count":83,"type":21},15,[24],"People with foot drop have an increased risk of tripping and falling, and this makes walking more difficult. Our colleagues at the Health Design Collective (HDC) have developed a shoe that aims to make it easier for people with foot drop to walk. People who have tested a prototype of the shoe, have told us that it makes their walking easier, but is also comfortable and unobtrusive. However, the investigators need more scientific evidence that this shoe helps reduce foot drop and improves walking in people with foot drop. The purpose of this small study, with only 15 participants, is to lay the foundations to design and carry out a bigger study. participants have been asked to take part if they are aged 18+ years and have experienced foot drop in the past 6 months or more. To be able to take part in this study participants need to be able to walk for 2 minutes without stopping (with or without their normal walking aid) and have sufficient movement in their ankle to use the shoe. Unfortunately, if the participant has severe swelling of their legs, deep vein thrombosis, or severe problems with the skin on their feet, they will not be able to take part in this study. If the participant agrees to take part, they will be fitted with a pair of the new shoes and asked to try them out for a period of 6 weeks. They will continue to wear any orthotics\u002Fankle foot orthotics or other aids that they are currently using. Before and during these six weeks the investigators will ask the participant to wear a small device that measures their physical activity. Just before and after these 6 weeks the investigators will invite the participant to Queen Margaret University for some walking tests with the new shoes. The investigators will also ask the participant to complete several questionnaires which they can do at home. After the 6-week shoe testing period the investigators will invite the participant for an interview, either in person or remotely, during which they can tell the researchers their thoughts about the new shoe. Participants will be asked to travel to Queen Margaret University, Musselburgh and all of their travel expenses to and from the university will be reimbursed. The study involves testing a new shoe which participants might find uncomfortable and take some time to get used to. The investigators will support participants throughout 6 weeks testing period to make sure that they are safe and free of pain when using the shoes. If participants experience any issues related to the shoes, they should stop wearing them and contact the investigators. The two study assessments will involve several walking tests that participants may find tiring. People who have tested an early prototype of the shoe, have told the research team that it makes their walking easier, but is also comfortable and unobtrusive. However, it is possible participants will not experience these benefits. The investigators hope this study also helps people in the future to find out more about how this research can develop the shoes and how it impacts people affected by foot drop. If participants find them useful, they can keep the shoes after taking part in the study. If they are interested in taking part in this study after reading this information sheet, please contact the researcher to discuss the study and ask any questions. If participants decide to take part, they will be asked to complete a paper or electronic consent form. If they are happy to sign the consent form, the research team will send them a short survey with a couple of questions such as their age, shoe size, health condition, and how long they have experienced foot drop. This will allow the research team to order shoes in the correct size for the participant. Once the study period starts, the participant will record any falls they have had over a period of 6 weeks in either a paper or electronic diary, whichever they prefer. It is valuable for the General Practitioner (GP), orthotist and podiatrist, to know who is taking part in research. If the participant has given the investigators consent to do so, the research team will inform the participants GP, orthotist and podiatrist that the participant is taking part in the study.\n\nIn addition, the participant will be sent a small, lightweight activity monitor (picture below) and asked to wear it by attaching it to their leg for a period of 7 days. This monitor records how many steps that are taken each day and how fast the person is walking. The participant will be asked to wear the monitor whilst sleeping, if possible, but they will need to remove it for bathing and swimming. After a period of about 6 weeks, the investigators will invite the participant to Queen Margaret University, Musselburgh to fit them with a pair of HDC shoes. If English is the 2nd language, the person may bring a translator if they wish. Any travel expenses to and from the University will be reimbursed.",[28],[88,89,90,91,92],"foot drop","gait","trips and falls","footwear","walking disability","NOT_YET_RECRUITING","2025-03-28",{"date":96,"type":38},"2025-04-04",{"date":98,"type":21},"2025-06-20",{"date":100,"type":21},"2025-12-31",{"name":102,"class":45},"Queen Margaret University",{"id":104,"slug":105,"hasResults":11,"nctId":106,"briefTitle":107,"officialTitle":108,"acronym":4,"eligibilityCriteria":109,"healthyVolunteers":11,"sex":16,"minAge":17,"maxAge":4,"enrollmentInfo":110,"targetDuration":4,"studyType":22,"phases":112,"briefSummary":113,"conditions":114,"keywords":4,"overallStatus":34,"whyStopped":4,"lastUpdateSubmitDate":116,"lastUpdatePostDateStruct":117,"startDateStruct":119,"completionDateStruct":121,"leadSponsor":123,"locationsCount":46},"100408159","ankle-robotics-after-stroke-100408159","NCT04594837","Ankle Robotics After Stroke","Portable Ankle Robotics to Reverse Foot Drop After Stroke","Inclusion Criteria:\n\n* Ages 18 and older\n* In the subacute phase of stroke recovery (\\>6 weeks to \\\u003C6 months post-stroke) with residual hemiparesis of the lower extremity that includes symptoms of foot-drop. - or - In the chronic phase of stroke recovery (\\>6 months post-stroke) with residual hemiparesis of the lower extremity that includes symptoms of foot-drop.\n* Clear indications of hemiparetic gait by clinical observation\n\nExclusion Criteria:\n\n* Cardiac history of (a) unstable angina, (b) recent (less than 3 months) myocardial infarction, congestive heart failure (NYHA category II); (c) hemodynamically significant valvular dysfunction\n* Hypertension that is a contraindication for routine physical therapy (greater than 160\u002F100 on two assessments).\n* Medical History: (a) recent hospitalization (less than 3 months) for severe medical disease, (b) symptomatic peripheral arterial occlusive disease, (c) orthopedic or chronic pain conditions that significantly alter gait function, (d) pulmonary or renal failure (e) active cancer\n* History of non-stroke neuromuscular disorder restricting gait.\n* Aphasia or cognitive functioning that confounds participation, defined as unable to follow 2 step commands or judgment of the medical officer or therapist.",{"count":111,"type":21},140,[24],"The randomized study (in Phase II of the U44) compares the efficacy and durability of 9 weeks (18 sessions) of robot-assisted physical therapy (PTR) versus physical therapy (PT) alone on foot drop as assessed by gait biomechanics (ankle angle at initial contact, peak swing ankle angle, number of heel-first strikes - % total steps, gait velocity) and blinded clinician assessment (dorsiflexion active range of motion, ankle muscle strength, assistive device needs).",[28,32,115],"Hemiparesis","2023-01-24",{"date":118,"type":38},"2023-01-26",{"date":120,"type":38},"2020-08-20",{"date":122,"type":21},"2025-02-28",{"name":124,"class":125},"NextStep Robotics Inc.","INDUSTRY",{"id":127,"slug":128,"hasResults":11,"nctId":129,"briefTitle":130,"officialTitle":130,"acronym":4,"eligibilityCriteria":131,"healthyVolunteers":11,"sex":16,"minAge":17,"maxAge":132,"enrollmentInfo":133,"targetDuration":4,"studyType":22,"phases":135,"briefSummary":136,"conditions":137,"keywords":4,"overallStatus":93,"whyStopped":4,"lastUpdateSubmitDate":141,"lastUpdatePostDateStruct":142,"startDateStruct":144,"completionDateStruct":146,"leadSponsor":148,"locationsCount":4},"100328479","walking-ankle-robot-for-foot-drop-in-aging-and-disabled-populations-a-demonstration-project-100328479","NCT03556709","Walking Ankle Robot for Foot Drop in Aging and Disabled Populations: A Demonstration Project","Inclusion Criteria:\n\n1. Men and women, aged 18 to 88 years\n2. Chronic foot drop and ankle weakness in one leg from a peripheral nervous system injury due to a neuromuscular or orthopedic injury\n3. Ability to walk 10 meters and arise from a chair with no human assistance (but usage of usual assistive device\\[s\\] is permitted)\n\nExclusion Criteria:\n\n1. Cardiac history of (a) unstable angina; (b) recent (less than 3 months) myocardial infarction, congestive heart failure (NYHA category II); and\u002For (c) hemodynamically significant valvular dysfunction\n2. Hypertension that is a contraindication for a bout of walking training (greater than 160\u002F100 mmHg on two assessments)\n3. Medical history of (a) recent hospitalization (less than 3 months) for severe medical disease; (b) symptomatic peripheral arterial occlusive disease; (c) orthopedic or chronic pain conditions that significantly alter gait function; (d) pulmonary or renal failure; and\u002For (e) active cancer\n4. Current participation in orthopedic or rehabilitation medical programs\n5. Active deep venous thrombosis\n6. Distal paretic leg skin lesions, infections, or soft tissue inflammation","88 Years",{"count":134,"type":21},100,[24],"The purpose of this research study is to test the utility of an ankle robot, when used during treadmill walking, in people with ankle weakness and foot drop from a peripheral nervous system injury due to neuromuscular or orthopedic injury.",[28,138,139,140],"Peripheral Nervous System Diseases","Gait Disorders, Neurologic","Mobility Limitation","2018-06-04",{"date":143,"type":38},"2018-06-14",{"date":145,"type":21},"2018-08-01",{"date":147,"type":21},"2028-12-31",{"name":149,"class":150},"Baltimore VA Medical Center","FED",{"id":152,"slug":153,"hasResults":11,"nctId":154,"briefTitle":155,"officialTitle":155,"acronym":4,"eligibilityCriteria":156,"healthyVolunteers":11,"sex":16,"minAge":17,"maxAge":132,"enrollmentInfo":157,"targetDuration":4,"studyType":22,"phases":158,"briefSummary":159,"conditions":160,"keywords":4,"overallStatus":93,"whyStopped":4,"lastUpdateSubmitDate":161,"lastUpdatePostDateStruct":162,"startDateStruct":164,"completionDateStruct":166,"leadSponsor":167,"locationsCount":46},"100326481","seated-ankle-robot-for-foot-drop-in-aging-and-disabled-populations-a-demonstration-project-100326481","NCT03530592","Seated Ankle Robot for Foot Drop in Aging and Disabled Populations: A Demonstration Project","Inclusion Criteria:\n\n1. Men and women, aged 18 to 88 years\n2. Chronic foot drop and ankle weakness in one leg from a peripheral nervous system injury due to a neuromuscular or orthopedic injury\n3. Ability to walk 10 meters and arise from a chair with no human assistance (but usage of usual assistive device\\[s\\] is permitted)\n\nExclusion Criteria:\n\n1. Medical history that would preclude participation in low-intensity seated robotic-assisted rehabilitation\n2. Current participation in orthopedic or rehabilitation medical programs\n3. Active deep venous thrombosis\n4. Distal paretic leg skin lesions, infections, or soft tissue inflammation",{"count":134,"type":21},[24],"The purpose of this research study is to test the utility of an ankle robot in people with ankle weakness and foot drop from a peripheral nervous system injury due to neuromuscular or orthopedic injury.",[138,139,28,140],"2018-05-08",{"date":163,"type":38},"2018-05-21",{"date":165,"type":21},"2018-06-01",{"date":147,"type":21},{"name":149,"class":150}]