[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"fracture-arm\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:fracture-arm":31},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,3,0,[8,50,81],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":15,"eligibilityCriteria":16,"healthyVolunteers":11,"sex":17,"minAge":18,"maxAge":4,"enrollmentInfo":19,"targetDuration":4,"studyType":22,"phases":23,"briefSummary":25,"conditions":26,"keywords":32,"overallStatus":37,"whyStopped":4,"lastUpdateSubmitDate":38,"lastUpdatePostDateStruct":39,"startDateStruct":42,"completionDateStruct":44,"leadSponsor":46,"locationsCount":49},"100634333","wrist-injury-strengthening-exercise-wise-versus-usual-care-advice-for-improving-pain-and-function-100634333",false,"NCT07538323","Wrist Injury Strengthening Exercise (WISE) Versus Usual Care Advice for Improving Pain and Function","Progressive Resistance and Flexibility Exercises Versus Usual Care Advice for Improving Pain and Function After Distal Radius Fracture in Adults Aged 50 Years or Over in Denmark: the WISE-DK Randomised Trial","WISE-DK","Inclusion Criteria:\n\n* Distal radius fracture treated surgically or non-surgically\n* Willing and able to give informed consent\n\nExclusion Criteria:\n\n* Injury is more than two months old\n* There is evidence that the patient would be unable to participate in therapy or a self-guided exercise program provided by a participating center or adhere to study procedures (including cognitive impairment and fracture\u002Fsurgery complications such as Complex Regional Pain Syndrome)\n* No e-mail address to receive electronic questionnaires\n* Open fractures with a Gustilo \\& Anderson grading \\>1","ALL","50 Years",{"count":20,"type":21},588,"ESTIMATED","INTERVENTIONAL",[24],"NA","The goal of this clinical trial is to find out whether a therapist-guided exercise program helps people aged 50 and older recover better, in terms of pain and function, after a wrist fracture, compared to the usual care advice they would normally receive. The main question it aims to answer is:\n\n• Will participants who receive a therapist-supervised exercise program have better improvement in pain and function, as measured by the Patient Rated Wrist Evaluation questionnaire, six months after their injury?\n\nResearchers will compare these participants with those who receive usual care, which includes advice on self-management, to see if the supervised exercise program leads to greater recovery.\n\nParticipants will:\n\n* Either receive supervised exercise, with a therapy session of up to 60 minutes and two additional sessions of up to 30 minutes each in addition to usual-care, or they will receive solely usual-care, consisting of advice on self-management.\n* Complete questionnaires electronically at baseline, 3-months, and 6-months.",[27,28,29,30,31],"Distal Radius Fracture","Colles Fracture","Wrist Fracture","Wrist Fractures","Fracture Arm",[33,34,35,36],"Exercise","Therapy","Resistance training","Strengthening exercise","RECRUITING","2026-06-26",{"date":40,"type":41},"2026-06-30","ACTUAL",{"date":43,"type":41},"2026-05-12",{"date":45,"type":21},"2029-12",{"name":47,"class":48},"University of Aarhus","OTHER",1,{"id":51,"slug":52,"hasResults":11,"nctId":53,"briefTitle":54,"officialTitle":55,"acronym":4,"eligibilityCriteria":56,"healthyVolunteers":11,"sex":17,"minAge":57,"maxAge":58,"enrollmentInfo":59,"targetDuration":4,"studyType":22,"phases":61,"briefSummary":63,"conditions":64,"keywords":4,"overallStatus":71,"whyStopped":4,"lastUpdateSubmitDate":72,"lastUpdatePostDateStruct":73,"startDateStruct":75,"completionDateStruct":77,"leadSponsor":79,"locationsCount":49},"100635444","phase-4-a-clinical-trial-on-the-use-of-lidocaine-infusion-during-surgery-for-pediatric-upper-extremity-fractures-and-its-impact-on-total-perioperative-opioid-requirements-100635444","NCT07552766","A Clinical Trial on the Use of Lidocaine Infusion During Surgery for Pediatric Upper Extremity Fractures and Its Impact on Total Perioperative Opioid Requirements","A Prospective, Randomized, Double-blind Trial of the Impact of Intraoperative Intravenous Lidocaine Infusion on Total Opioid Requirements in Children Undergoing Surgical Fixation of Upper Extremity Long Bone Fractures Under General Anesthesia","Inclusion Criteria:\n\n* Patients aged 3-18 years\n* Patients \\> 10 kg\n* Patients who present to Nemours Children's Hospital - Delaware Valley (NCH-DE) for surgical fixation of upper extremity fractures from distal humerus to distal radius\n\nExclusion Criteria:\n\n* Children \\\u003C 3 years or \\> 18 years\n* Patients with allergy to local anesthetics\n* Patients who are eligible for an receive a peripheral nerve block\n* Patients with multi-trauma or open fractures\n* Patients with previous history of seizure disorder\n* Patients with conduction abnormalities or cardiac arrhythmia requiring chronic treatment\n* Patients on strong CYP450 inhibitors (fluvoxamine, erythromycin, ciprofloxacin, rifampin, allopurinol, ketoconazole, itraconazole)\n* Patients with chronic kidney or liver dysfunction\n* Patients with planned use of continuous infusion pain medications (opioids, ketamine, alpha-2- agonists)\n* Patients with positive pregnancy test prior to surgery or nursing mothers\n* Patients who parents decline enrollment","3 Years","18 Years",{"count":60,"type":21},90,[62],"PHASE4","This study is a prospective, randomized, double-blind clinical trial evaluating whether intraoperative intravenous lidocaine infusion (IVLI) reduces opioid requirements and improves postoperative pain control in children undergoing surgical fixation of upper extremity long bone fractures under general anesthesia. Ninety pediatric patients, ages 3-18 will be enrolled and randomized 1:1 to receive either IV lidocaine or placebo (normal saline) during surgery.\n\nAll participants will receive standardized anesthesia care and postoperative pain management. Opioid consumption and pain scores will be measured intraoperatively and throughout the postoperative recovery, with the primary outcome focused on total opioid use 60 minutes after arrival to the post-anesthesia care unit (PACU). Secondary outcomes include opioid use at additional time points, postoperative pain scores, PACU length of stay, rescue antiemetic use and the relationship between infusion duration and outcomes.\n\nPatients will be closely monitored for signs of local anesthetic systemic toxicity and other adverse events. The goal of this study is to determine whether IV lidocaine is an effective opioid-sparing adjunct in pediatric orthopedic surgery and to support safer, multimodal analgesia strategies.",[31,65,66,67,68,69,70],"Fracture Closed of Lower End of Forearm, Unspecified","Fracture Elbow","Fracture Fixation","Fracture Fixation, Internal","Fracture Forearm","Fracture Distal Radius","NOT_YET_RECRUITING","2026-04-22",{"date":74,"type":41},"2026-04-27",{"date":76,"type":21},"2026-05",{"date":78,"type":21},"2029-07",{"name":80,"class":48},"Nemours Children's Clinic",{"id":82,"slug":83,"hasResults":11,"nctId":84,"briefTitle":85,"officialTitle":86,"acronym":4,"eligibilityCriteria":87,"healthyVolunteers":11,"sex":17,"minAge":4,"maxAge":4,"enrollmentInfo":88,"targetDuration":90,"studyType":91,"phases":4,"briefSummary":92,"conditions":93,"keywords":100,"overallStatus":37,"whyStopped":4,"lastUpdateSubmitDate":104,"lastUpdatePostDateStruct":105,"startDateStruct":107,"completionDateStruct":109,"leadSponsor":111,"locationsCount":114},"100385462","safety-efficacy--use-of-vivigen-cellular-bone-matrix-allograft-in-orthopaedic-fracture-care-100385462","NCT04299022","Safety, Efficacy, & Use of ViviGen Cellular Bone Matrix Allograft in Orthopaedic Fracture Care","Safety, Efficacy, & Use of ViviGen Cellular Bone Matrix Allograft in Orthopaedic Fracture Care: A Multi-Center Prospective Registry and Retrospective Data Collection Study","Prospective Cohort Inclusion Criteria:\n\n* Any skeletally mature patient treated with Vivigen bone graft in the setting of an acute fracture, delayed, non-union or fusion setting will be eligible for inclusion.\n\nRetrospective Cohort Inclusion Criteria:\n\n\\- Any skeletally mature patient treated with adjunct bone graft in the setting of an acute fracture, delayed, non-union or fusion setting will eligible for inclusion.\n\nProspective Cohort Exclusion Criteria:\n\n1. Patients unable to understand either an English or Spanish consent will be excluded.\n2. Patients unable to consent secondary to dementia and\u002For other mental\u002Fpsychiatric diagnoses will be excluded.",{"count":89,"type":21},250,"24 Months","OBSERVATIONAL","Prospective registry and retrospective data collection study to assess the efficacy and safety of Vivigen Cellular Bone Matrix (Vivigen) in orthopaedic trauma patients who require bone grafting in the acute, delayed, non-union fracture as well as use in fusion procedure settings.",[94,95,96,97,98,99,31],"Fractures, Bone","Nonunion of Fracture","Fractures, Open","Fractures, Ununited","Fracture, Tibial","Fracture of Femur",[101,102,103],"fracture","nonunion","allograft","2025-03-28",{"date":106,"type":41},"2025-04-02",{"date":108,"type":41},"2021-06-01",{"date":110,"type":21},"2026-07-31",{"name":112,"class":113},"LifeNet Health","INDUSTRY",4]