[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"fracture-dislocation-of-upper-limb-joint\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:fracture-dislocation-of-upper-limb-joint":25},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,2,0,[8,46],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":4,"eligibilityCriteria":15,"healthyVolunteers":11,"sex":16,"minAge":17,"maxAge":4,"enrollmentInfo":18,"targetDuration":4,"studyType":21,"phases":4,"briefSummary":22,"conditions":23,"keywords":27,"overallStatus":34,"whyStopped":4,"lastUpdateSubmitDate":35,"lastUpdatePostDateStruct":36,"startDateStruct":39,"completionDateStruct":41,"leadSponsor":43,"locationsCount":4},"100604283","relationship-between-mortality-rates-of-fractures-in-different-sites-and-several-factors-in-elderly-patients-100604283",false,"NCT07147504","Relationship Between Mortality Rates of Fractures in Different Sites and Several Factors in Elderly Patients","A Retrospective Study on the Relationship Between Mortality Rates of Fractures in Different Sites and Factors Such as Age, Metabolism, and Nutritional Status in Elderly Patients: A Single-center Retrospective Study","Inclusion Criteria:\n\n* Patients admitted to the National Orthopedic Center of Shanghai Sixth People's Hospital between January 1, 2010, and December 31, 2019;\n* Age ≥ 60 years;\n* Shanghai resident registration;\n* Diagnosed with limb or spinal fractures and receiving surgical treatment at Shanghai Sixth People's Hospital.\n\nExclusion Criteria:\n\n* Multiple fractures;\n* Conservative treatment selected;\n* Incomplete medical records.","ALL","60 Years",{"count":19,"type":20},3000,"ESTIMATED","OBSERVATIONAL","Background and Purpose:\n\nAs people age, bones become weaker and break more easily. Older adults (people 60 years and older) who break bones may face serious health problems and have a higher chance of dying compared to younger people. The location of the broken bone, a person's age, and overall health may affect the chances of survival.\n\nThis study will conduct a retrospective analysis of medical records from geriatric patients who underwent surgical intervention for bone fractures at Shanghai Sixth People's Hospital between 2010 and 2019. The primary objective is to identify the key prognostic factors associated with post-operative mortality in this patient cohort.\n\nThe study will retrospectively analyze the medical records of patients who meet all of the following criteria:\n\nAged 60 years or older at the time of fracture diagnosis. Residents of Shanghai. Diagnosed with a fracture of the extremities (upper or lower limbs) or the spine.\n\nUnderwent surgical intervention for the diagnosed fracture.\n\nThe investigators will assess the following variables as potential prognostic factors for post-operative mortality:\n\nFracture Characteristics: The anatomical location of the fracture (e.g., hip, spine, upper extremity, lower extremity).\n\nPatient Demographics: The patient's age at the time of injury. Physiological Status: Indicators of the patient's nutritional and metabolic health.\n\nComorbidities: The presence and severity of pre-existing medical conditions.\n\nHow investigators will do this study:\n\nThis study is designed as a retrospective cohort analysis. Data will be systematically extracted from existing patient medical records. As an observational study, it involves no new interventions or modifications to patient care. The primary endpoint is all-cause mortality, which will be assessed at 1, 3, and 5 years post-operatively to determine long-term survival rates.\n\nInvestigators will group participants by:\n\nThe location of fracture (20 different bone locations); Age (60-65, 66-70, 71-75, 76-80, and over 80 years old); Nutrition and health status.\n\nWhy This Study Matters:\n\nThe results of this study will help doctors better understand which older patients are at higher risk after breaking a bone. This information could help healthcare teams provide better care and potentially save lives by identifying patients who need extra attention and treatment.\n\nStudy Details:\n\nThis study will examine records from approximately 2000 participants; All participants already received their treatment between 2010-2019; No new treatments or procedures will be performed; Participant's privacy will be completely protected; The study will take about 14 months to complete;\n\nThis research will help improve care for older adults who experience bone fractures and may guide treatment decisions for future patients.",[24,25,26],"Fracture Lower Leg","Fracture Dislocation of Upper Limb Joint","Spinal Fractures",[28,29,30,31,32,33],"fracture","Limb fractures","Spinal fractures","Elderly people","the old","Survival rate","NOT_YET_RECRUITING","2025-08-29",{"date":37,"type":38},"2025-09-08","ACTUAL",{"date":40,"type":20},"2025-09-01",{"date":42,"type":20},"2026-02-28",{"name":44,"class":45},"Shanghai 6th People's Hospital","OTHER",{"id":47,"slug":48,"hasResults":11,"nctId":49,"briefTitle":50,"officialTitle":50,"acronym":4,"eligibilityCriteria":51,"healthyVolunteers":11,"sex":16,"minAge":52,"maxAge":4,"enrollmentInfo":53,"targetDuration":4,"studyType":55,"phases":56,"briefSummary":58,"conditions":59,"keywords":64,"overallStatus":75,"whyStopped":4,"lastUpdateSubmitDate":76,"lastUpdatePostDateStruct":77,"startDateStruct":79,"completionDateStruct":81,"leadSponsor":83,"locationsCount":85},"100568224","phase-4-brachial-plexus-nerve-block-versus-haematoma-block-for-closed-reduction-of-distal-radius-fracture-in-adults---the-block-trial-a-multicentre-randomised-controlled-trial-100568224","NCT06678438","Brachial Plexus Nerve Block Versus Haematoma Block for Closed Reduction of Distal Radius Fracture in Adults - The BLOCK Trial. A Multicentre Randomised Controlled Trial.","Inclusion Criteria:\n\n* Adults (age ≥ 18 years) with a distal radius fracture in need of closed reduction\n\nExclusion Criteria:\n\n* Patients who would never qualify for surgery according to local guidelines\n* Lack of informed consent\n* No Danish Central Person Register (CPR) number\n* Allergies to the trial medication\n* Distal radius fracture initially deemed to require surgery regardless of the outcome of the closed reduction\n* Open fractures (fracture-related wound requiring sutures)\n* Other fractures on the same extremity ((NOT including distal ulna fracture(s))\n* Bilateral distal radius fractures both requiring closed reduction\n* Concomitant medical or surgical condition taking priority over the closed reduction of the distal radius fracture.","18 Years",{"count":54,"type":20},1716,"INTERVENTIONAL",[57],"PHASE4","The aim of the project is to evaluate the beneficial and harmful effects of an ultrasound-guided brachial plexus nerve block for patients with a distal radius (wrist) fracture in the need of realignment of fractured bone endings without cutting the skin (closed reduction), in comparison to a haematoma block, which is standard care in Denmark.\n\nEvery participant will receive one of the following types of anaesthesia for the realignment of the wrist fracture:\n\n1. A nerve block of the arm (plexus brachialis block)\n2. A haematoma block, which is the current standard anaesthesia in the emergency departments.",[60,61,25,62,63],"Distal Radius Fractures","Fracture Dislocation","Colles' Fracture","Closed Reduction of Fracture and Application of Plaster Cast",[65,66,67,68,69,70,71,72,73,74],"Lidocaine","Local anaesthesia","Regional anaesthesia","Peripheral nerve block","Brachial plexus block","Lateral infraclavicular block","Axillary plexus block","Distal radius fracture","Colles' fracture","Wrist fracture","RECRUITING","2025-06-12",{"date":78,"type":38},"2025-06-17",{"date":80,"type":38},"2024-12-10",{"date":82,"type":20},"2027-04",{"name":84,"class":45},"Nordsjaellands Hospital",1]