[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"fraility\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:fraility":25},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,3,0,[8,49,76],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":4,"eligibilityCriteria":15,"healthyVolunteers":11,"sex":16,"minAge":17,"maxAge":4,"enrollmentInfo":18,"targetDuration":21,"studyType":22,"phases":4,"briefSummary":23,"conditions":24,"keywords":28,"overallStatus":36,"whyStopped":4,"lastUpdateSubmitDate":37,"lastUpdatePostDateStruct":38,"startDateStruct":41,"completionDateStruct":43,"leadSponsor":45,"locationsCount":48},"100642976","the-relationship-between-preoperative-anxiety-level-and-frailty-score-in-elderly-patients-scheduled-for-elective-hip-arthroplasty-a-prospective-observational-study-100642976",false,"NCT07633483","The Relationship Between Preoperative Anxiety Level and Frailty Score in Elderly Patients Scheduled for Elective Hip Arthroplasty: A Prospective Observational Study","Assessment of the Relationship Between Preoperative Anxiety Level Measured by the Hamilton Anxiety Rating Scale and Frailty Score Assessed by the FRAIL Scale in Elderly Patients Aged 65 Years and Older Scheduled for Elective Hip Arthroplasty: A Prospective Observational Single-Center Study","Inclusion Criteria:\n\n* Patients of both sexes aged 65 years and older\n* Patients with ASA physical status classification I, II, or III scheduled for elective hip arthroplasty\n* Patients who voluntarily agree to participate in the study\n* Patients with intact orientation and sufficient cooperation for assessment\n\nExclusion Criteria:\n\n* Patients with ASA physical status classification IV or V\n* Patients who refuse to participate in the study\n* Patients with impaired orientation or insufficient cooperation for assessment\n* Patients scheduled for emergency surgery\n* Patients to be operated during an active intensive care unit admission","ALL","65 Years",{"count":19,"type":20},142,"ESTIMATED","1 Week","OBSERVATIONAL","Frailty is a state of vulnerability resulting from decreased physiological reserve across multiple organ systems, impairing an individual's ability to withstand stressors. As the elderly population grows worldwide, the proportion of older adults undergoing surgical procedures continues to rise, and frailty is expected to become increasingly prevalent among surgical candidates.\n\nAnxiety is one of the most common psychiatric conditions, affecting approximately one in three individuals globally. Preoperative anxiety may negatively influence surgical outcomes, particularly in older and more vulnerable patients.\n\nThis prospective observational study aims to evaluate the relationship between preoperative anxiety level and frailty score in elderly patients aged 65 years and older scheduled for elective hip arthroplasty. Frailty will be assessed using the FRAIL Scale (Fatigue, Resistance, Ambulation, Illness, Loss of Weight), and anxiety will be measured using the Hamilton Anxiety Rating Scale (HAM-A). Secondary outcomes include the prevalence of frailty and anxiety, the effect of frailty on length of hospital stay, postoperative intensive care unit admission rates, and the relationship between frailty and preoperative laboratory and hemodynamic parameters.",[25,26,27],"Fraility","Anxiety, Preoperative","Hip Arthroplasty",[25,29,30,31,27,32,33,34,35],"FRAIL Scale","Preoperative Anxiety","Hamilton Anxiety Rating Scale","Elderly","Geriatric","Observational Study","Anesthesiology","RECRUITING","2026-06-04",{"date":39,"type":40},"2026-06-08","ACTUAL",{"date":42,"type":40},"2024-12-01",{"date":44,"type":20},"2026-07-01",{"name":46,"class":47},"Başakşehir Çam & Sakura City Hospital","OTHER_GOV",1,{"id":50,"slug":51,"hasResults":11,"nctId":52,"briefTitle":53,"officialTitle":54,"acronym":4,"eligibilityCriteria":55,"healthyVolunteers":11,"sex":16,"minAge":17,"maxAge":4,"enrollmentInfo":56,"targetDuration":4,"studyType":22,"phases":4,"briefSummary":58,"conditions":59,"keywords":62,"overallStatus":36,"whyStopped":4,"lastUpdateSubmitDate":66,"lastUpdatePostDateStruct":67,"startDateStruct":69,"completionDateStruct":71,"leadSponsor":73,"locationsCount":48},"100626978","frailty-and-outcomes-in-older-emergency-department-patients-with-pneumonia-100626978","NCT07442656","Frailty and Outcomes in Older Emergency Department Patients With Pneumonia","Impact of Clinical Frailty Scale on Morbidity and Mortality in Older Adults Diagnosed With Pneumonia in the Emergency Department: A Prospective Observational Cohort Study","Inclusion Criteria:\n\n* Age ≥65 years\n* Clinical and radiological diagnosis of pneumonia in the emergency department\n* Ability to obtain informed consent from the patient or legal representative\n* Availability of a caregiver or relative able to describe baseline functional status\n\nExclusion Criteria:\n\n* Presentation with cardiopulmonary arrest or ongoing cardiopulmonary resuscitation at admission\n* Confirmed COVID-19 pneumonia\n* Inability to obtain reliable baseline functional history due to absence of an informant\n* Refusal to provide informed consent",{"count":57,"type":20},150,"Pneumonia is one of the leading causes of infection-related mortality in the older population. Traditional severity scores used in emergency departments, such as the Pneumonia Severity Index (PSI) and CURB-65, primarily focus on acute physiological derangements and may not adequately capture biological reserve and frailty in older adults. Frailty is a geriatric syndrome reflecting increased vulnerability to stressors and reduced recovery capacity.\n\nThis prospective observational cohort study aims to evaluate the predictive value of the Clinical Frailty Scale (CFS) for in-hospital mortality, 30-day mortality, and morbidity in patients aged 65 years and older presenting to the emergency department with pneumonia. Additionally, the study will assess whether incorporating frailty assessment into existing pneumonia severity scores improves prognostic accuracy.",[60,25,61],"Community-Acquired Pneumonia","Hospitalizations",[25,63,64,65],"Clinical Fraility Scale","Older adults","Geriatric Emergency Medicine","2026-02-26",{"date":68,"type":40},"2026-03-02",{"date":70,"type":40},"2026-01-01",{"date":72,"type":20},"2026-04-30",{"name":74,"class":75},"Ege University","OTHER",{"id":77,"slug":78,"hasResults":11,"nctId":79,"briefTitle":80,"officialTitle":81,"acronym":4,"eligibilityCriteria":82,"healthyVolunteers":11,"sex":16,"minAge":17,"maxAge":4,"enrollmentInfo":83,"targetDuration":4,"studyType":22,"phases":4,"briefSummary":85,"conditions":86,"keywords":4,"overallStatus":88,"whyStopped":4,"lastUpdateSubmitDate":89,"lastUpdatePostDateStruct":90,"startDateStruct":92,"completionDateStruct":94,"leadSponsor":96,"locationsCount":4},"100619971","the-effect-of-frailty-on-hypotension-after-anesthesia-induction-100619971","NCT07351552","The Effect of Frailty on Hypotension After Anesthesia Induction","The Effect of Frailty in Geriatric Patients on Hypotension Observed After Anesthesia Induction","Inclusion Criteria:\n\n* Patients who do not have difficulty communicating,\n* have good cognitive function,\n* scheduled for surgery under general anesthesia\n\nExclusion Criteria:\n\n* Patients admitted for surgery in emergency situations\n* Patients with active malignancy\n* Patients with physical disabilities and impairments (limb amputations, stroke sequelae, unable to speak, hearing problems)\n* Patients with acute infections\n* Patients with acute illnesses (decompensated congestive heart failure, recent myocardial infarction\u002Fstroke, COPD exacerbation)\n* Patients who have been hospitalized or undergone surgery within the last month\n* Patients with advanced dementia\n* Patients who are unable to provide a medical history or cooperate",{"count":84,"type":20},80,"Frailty is defined as a state of weakness resulting from a decrease in physiological reserves due to physiological changes, diseases, and\u002For malnutrition associated with advancing age. Frail older adults face increased mortality, morbidity, and healthcare costs when exposed to stressors, making this issue increasingly important. The FRAIL Scale, developed by Morley et al. , is a 5-item measure that assesses frailty. The FRAIL Scale has been validated in many countries and has been proven to be an effective method for detecting frailty. This scale assesses the patient's fatigue, resistance, mobility, weight loss, and other diseases. In the 5-item FRAIL scale, patients receive 0 or 1 point based on their answers, and a total of 0 points is considered non-frail, 1-2 points is considered pre-frail, and \\>2 points is considered frail.\n\nFrailty is associated with a higher risk of postoperative complications. Rothenberg and colleagues reported in a study involving more than 400,000 patients that frailty doubles the risk of postoperative complications .\n\nHypotension following anesthesia induction is a common complication in geriatric patients. Decreased cardiopulmonary reserve with age leads to an exaggerated drop in blood pressure during induction .\n\nIn this study, the investigators aimed to determine the effect of frailty level in geriatric patients on hypotension observed after anesthesia induction.",[25,87],"Hypotension","NOT_YET_RECRUITING","2026-01-09",{"date":91,"type":40},"2026-01-20",{"date":93,"type":20},"2026-01-15",{"date":95,"type":20},"2026-06-15",{"name":97,"class":75},"Selcuk University"]