[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"full-thickness-skin-defects\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:full-thickness-skin-defects":27},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,1,0,[8],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":15,"eligibilityCriteria":16,"healthyVolunteers":11,"sex":17,"minAge":4,"maxAge":4,"enrollmentInfo":18,"targetDuration":4,"studyType":21,"phases":4,"briefSummary":22,"conditions":23,"keywords":4,"overallStatus":28,"whyStopped":4,"lastUpdateSubmitDate":29,"lastUpdatePostDateStruct":30,"startDateStruct":33,"completionDateStruct":35,"leadSponsor":37,"locationsCount":40},"100624895","the-use-of-cultured-dermal-epithelial-autografts-in-severely-burned-patients-100624895",false,"NCT07415577","The Use of Cultured (Dermal) Epithelial Autografts in Severely Burned Patients","Multicenter Cohort Study for the Use of Cultured Epithelial Autografts (CEA) or Cultured Dermal Epidermal Autografts (CDEA) in Severely Burned Patients","Swisskera","Inclusion Criteria:\n\n* Patients who have undergone treatment at the three Swiss burn centres and received grafts utilizing CEA since the introduction of the CEA technique in Switzerland (from 1985 to 2023) will be invited to participate in this study.\n* Availability of clinical data, including at minimum demographic information and the date and time of CEA\u002FCDEA transplantation.\n* Signed informed consent from the patient or his\u002Fher legal representative\u002Frelatives.\n\nExclusion Criteria:\n\n* Refusal of participation in the study by the patient or his\u002Fher legal representative\u002Frelatives.\n* Patients, who are, of any reason, unable to attend a study visit at one of the study sites or in their home","ALL",{"count":19,"type":20},236,"ESTIMATED","OBSERVATIONAL","The Swisskera project is a multicenter follow-up study at the three Swiss burn centers evaluating long-term outcomes after burn wound coverage with lab-grown epithelial grafts, specifically cultured epithelial autograft (CEA) and, where applicable, cultured dermal-epidermal autograft (CDEA). Patients who received CEA\u002FCDEA between 1985 and 2023 will be invited for a study visit , using available clinical records and standardized long-term scar and skin assessments.\n\nLong-term skin quality will be evaluated by comparing the previously transplanted area with a matched healthy skin reference site using non-invasive measurements (e.g., thickness, transepidermal water loss, hydration, elasticity, and color). Optional small punch biopsies may be obtained from transplanted areas (under local anesthesia or during clinically indicated anesthesia) for histological and immunohistochemical characterization of scar tissue remodeling, including collagen and elastin architecture, vascularization, nerve fiber ingrowth, inflammatory cell patterns, and melanocyte distribution.",[24,25,26,27],"Burn Degree Second","Burn Degree Third","Skin Transplantation","Full Thickness Skin Defects","NOT_YET_RECRUITING","2026-05-20",{"date":31,"type":32},"2026-05-26","ACTUAL",{"date":34,"type":20},"2026-12-01",{"date":36,"type":20},"2030-12-31",{"name":38,"class":39},"University Children's Hospital, Zurich","OTHER",3]