[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"functional-abdominal-pain-syndrome\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:functional-abdominal-pain-syndrome":31},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,5,0,[8,48,87,108,144],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":13,"acronym":14,"eligibilityCriteria":15,"healthyVolunteers":16,"sex":17,"minAge":18,"maxAge":19,"enrollmentInfo":20,"targetDuration":4,"studyType":23,"phases":24,"briefSummary":26,"conditions":27,"keywords":33,"overallStatus":35,"whyStopped":4,"lastUpdateSubmitDate":36,"lastUpdatePostDateStruct":37,"startDateStruct":40,"completionDateStruct":42,"leadSponsor":44,"locationsCount":47},"100501841","supraspinal-processing-of-sensory-aspects-of-pain-100501841",false,"NCT05814497","Supraspinal Processing of Sensory Aspects of Pain","SCP","Inclusion Criteria:\n\n* Patients will need a diagnosis of a chronic pain derived congruent with ICD-11 criteria related to headache (migraine, daily headache), abdominal (FAPD), localized MSK (single limb\u002Fjoint, low back or chest pain), diffuse MSK (widespread MSK pain), or CRPS\n* If on medications, they need to be on stable doses of prescribed pain and\u002For psychiatric medications for 4 weeks before the baseline study visit.\n* Male or female, age 10 -17 (inclusive)\n* English speaking, able to complete interviews and questionnaires in English\n\nExclusion Criteria:\n\n* Weight\u002Fsize incompatible with MRI scanner\n* Orthodontic braces, metallic or electronic implants, or other metal objects in the body which obscure or interfere with the MRI, or pose a risk from heating, movement, or malfunction in the MRI environment\n* Claustrophobia\n* Youth who are pregnant\n* Any comorbid rheumatic disease, diagnosis of epilepsy, other neurological diseases, or medical condition (e.g. diabetes, cancer, IBD)\n* Present psychiatric disease as defined by DSM IV (e.g. psychosis, bipolar disorder, major depression, generalized anxiety disorder), alcohol or drug dependence, or documented developmental delays or impairments (e.g., autism, cerebral palsy, ADHD, or mental retardation) that, in the opinion of the investigator, would interfere with adherence to study requirements or safe participation in the study\n* Skin conditions or past skin damage on the arms or legs in or near sites of sensory testing\n* Outside the age range (9 years old or younger; 18 years or older) at the time of consent\n* History of \\> 1 month opioid treatment.",true,"ALL","10 Years","17 Years",{"count":21,"type":22},255,"ESTIMATED","INTERVENTIONAL",[25],"NA","The goal of this basic science study is to learn about the brain mechanisms of chronic pain across different chronic pain syndromes in pediatric patients. The main questions it aims to answer are:\n\n* Are there shared and distinct brain systems engaged by different forms of pediatric chronic pain?\n* What are predictors of recovery from chronic pain?\n* What brain systems are associated with the spread of pain?\n\nFor this study participants will undergo:\n\n* Functional Magnetic Resonance Imaging (fMRI)\n* Quantitative Sensory Testing\n* Psychological Assessments",[28,29,30,31,32],"Migraine in Children","Complex Regional Pain Syndromes","Musculoskeletal Pain","Functional Abdominal Pain Syndrome","Fibromyalgia",[34],"chronic pain","RECRUITING","2026-06-04",{"date":38,"type":39},"2026-06-05","ACTUAL",{"date":41,"type":39},"2023-05-01",{"date":43,"type":22},"2027-06-30",{"name":45,"class":46},"Children's Hospital Medical Center, Cincinnati","OTHER",1,{"id":49,"slug":50,"hasResults":11,"nctId":51,"briefTitle":52,"officialTitle":53,"acronym":54,"eligibilityCriteria":55,"healthyVolunteers":11,"sex":17,"minAge":56,"maxAge":57,"enrollmentInfo":58,"targetDuration":60,"studyType":61,"phases":4,"briefSummary":62,"conditions":63,"keywords":75,"overallStatus":35,"whyStopped":4,"lastUpdateSubmitDate":78,"lastUpdatePostDateStruct":79,"startDateStruct":81,"completionDateStruct":83,"leadSponsor":85,"locationsCount":47},"100540310","seattle-spatial-transcriptomic-research-in-inflammatory-bowel-disease-evaluation-stride-100540310","NCT06315179","Seattle Spatial Transcriptomic Research in Inflammatory Bowel Disease Evaluation (STRIDE)","Seattle Spatial Transcriptomic Research in Inflammatory Bowel Disease Evaluation","STRIDE","Inclusion Criteria:\n\n* Suspected diagnosis of CD (Crohn's Disease), UC (Ulcerative Colitis) or Indeterminate colitis (IC)\n\nExclusion Criteria:\n\n* Evidence of Other Complicating Medical Issues:\n* Other serious medical conditions, such as neurological, liver, kidney, or systemic disease\n* Pregnancy\n* Tobacco, alcohol, or illicit drug abuse","6 Years","21 Years",{"count":59,"type":22},200,"3 Years","OBSERVATIONAL","This is a prospective observational study collecting long-term clinical data and samples for research in pediatric inflammatory bowel disease (IBD) patients with gut inflammation and a control cohort of pediatric patients with disorders of the brain-gut interactions (DBGI) with no detectable gut inflammation.",[64,65,66,67,31,68,69,70,71,72,73,74],"Inflammatory Bowel Diseases","Crohn Disease","Ulcerative Colitis","Indeterminate Colitis","Functional Bowel Disorder","Esophageal Diseases","Gastroduodenal Disorder","Bowel Dysfunction","Gallbladder Diseases","Sphincter of Oddi Dysfunction","Anorectal Disorder",[76,77],"IBD","DGBI","2026-04-21",{"date":80,"type":39},"2026-04-24",{"date":82,"type":39},"2024-05-10",{"date":84,"type":22},"2030-01",{"name":86,"class":46},"Seattle Children's Hospital",{"id":88,"slug":89,"hasResults":11,"nctId":90,"briefTitle":91,"officialTitle":92,"acronym":4,"eligibilityCriteria":93,"healthyVolunteers":16,"sex":17,"minAge":94,"maxAge":19,"enrollmentInfo":95,"targetDuration":4,"studyType":61,"phases":4,"briefSummary":97,"conditions":98,"keywords":4,"overallStatus":35,"whyStopped":4,"lastUpdateSubmitDate":99,"lastUpdatePostDateStruct":100,"startDateStruct":102,"completionDateStruct":104,"leadSponsor":106,"locationsCount":47},"100511884","icbt-for-children-with-fapds---the-childs-pain-regulation-100511884","NCT05945251","ICBT for Children With FAPDs - the Child's Pain Regulation","Individualized Online Cognitive Behavioral Therapy for Children With Functional Abdominal Pain Disorders - the Child's Pain Regulation","Inclusion Criteria:\n\nChildren 8-17 years with FAPDs: Have been offered treatment at BUP Internetbehandling for FAPDs.\n\nChildren 8-17 years without FAPDs: Not affected by recurrent (every week) or persistant pain during the last year.\n\nExclusion Criteria:\n\nContraindication for MR (metal implant or metal object in body, claustrophobia, pregnancy)","8 Years",{"count":96,"type":22},80,"Functional abdominal pain disorders (FAPDs) in children are common (14%) and abdominal pain has increased rapidly in children during the last ten years in Sweden. Many children with FAPDs have low quality of life, missed school days, and about 30-40% suffer from psychiatric comorbidity. FAPDs are often sustained into adulthood and a large Swedish cohort study showed that abdominal pain during childhood is an independent strong predictor anxiety and depression later in life. Internet-cognitive behavioral therapy (Internet-CBT) can improve FAPD symptoms, but a significant number of children does not respond to the treatment.\n\nWe will here determine the pain regulation in children with FAPDs, compared with healthy controls, and assess:\n\nWhat aspects of the child's pain regulation is related to improvement for children with FAPDs engaging in Internet-CBT?\n\nDoes some aspects of the child's pain regulation change during treatment?",[31],"2025-08-26",{"date":101,"type":39},"2025-09-03",{"date":103,"type":39},"2023-11-01",{"date":105,"type":22},"2026-01",{"name":107,"class":46},"Karolinska Institutet",{"id":109,"slug":110,"hasResults":11,"nctId":111,"briefTitle":112,"officialTitle":113,"acronym":114,"eligibilityCriteria":115,"healthyVolunteers":16,"sex":17,"minAge":116,"maxAge":117,"enrollmentInfo":118,"targetDuration":4,"studyType":23,"phases":120,"briefSummary":123,"conditions":124,"keywords":127,"overallStatus":35,"whyStopped":4,"lastUpdateSubmitDate":135,"lastUpdatePostDateStruct":136,"startDateStruct":138,"completionDateStruct":140,"leadSponsor":142,"locationsCount":47},"100536756","phase-1-exploring-treatments-for-childrens-abdominal-pain-comparing-trimebutine-and-probiotics-100536756","NCT06268964","Exploring Treatments for Children's Abdominal Pain: Comparing Trimebutine and Probiotics","Comparative Effect of Trimebutine and Probiotics on Functional Abdominal Pain Disorders (FAPD) in Children: Randomized Clinical Trial (RCT)","FAPD_RCT","Inclusion Criteria:\n\n* Pediatric patients from 4 to 18 years old.\n* Meeting the Rome IV criteria for any of the Functional Abdominal Pain Disorders (Functional Dyspepsia, Irritable Bowel Syndrome, Abdominal Migraine or Functional Abdominal Pain Not Otherwise Specified)\n* Having the informed consent signed by the parents or legal guardians of the minor.\n\nExclusion Criteria:\n\n* Patients presenting abdominal pain of organic cause.\n* Immunosuppressed patients.\n* Patients with previous hypersensitivity to the study drug.\n\nElimination Criteria:\n\n* Voluntary withdrawal from the study.\n* Patients not adhering to treatment (less than 80%)\n* Patients participating in another study simultaneously.\n* Patients being treated by another doctor simultaneously.","4 Years","18 Years",{"count":119,"type":22},82,[121,122],"PHASE1","PHASE2","The goal of this clinical trial is to test the effectiveness of trimebutine and probiotics in treating Functional Abdominal Pain Disorders (FAPD) in a pediatric population. The main questions it aims to answer are: Is trimebutine effective in reducing the symptoms of FAPD in children? Are probiotics effective in reducing the symptoms of FAPD in children? Participants will be randomly assigned to one of three treatment groups (trimebutine\u002Fprobiotics, probiotics\u002Fplacebo, or trimebutine\u002Fplacebo). Undergo measurements for pain and other relevant metrics at the start of the study, after 4 weeks, and after 8 weeks.\n\nResearchers will compare the trimebutine\u002Fprobiotics group to the probiotics\u002Fplacebo and the trimebutine\u002Fplacebo groups to see if there are significant differences in the efficacy of these treatments in reducing symptoms of FAPD in children.",[31,125,126],"Functional Gastrointestinal Disorders","Irritable Bowel Syndrome Variant of Childhood",[128,129,130,131,132,133,134],"functional abdominal pain","randomized clinical trial","placebo","double-blind","trimebutine","Lactobacillus rhamnosus","pediatrics","2024-08-13",{"date":137,"type":39},"2024-08-16",{"date":139,"type":22},"2024-09-01",{"date":141,"type":22},"2025-06-30",{"name":143,"class":46},"Universidad de Colima",{"id":145,"slug":146,"hasResults":11,"nctId":147,"briefTitle":148,"officialTitle":149,"acronym":150,"eligibilityCriteria":151,"healthyVolunteers":16,"sex":17,"minAge":94,"maxAge":152,"enrollmentInfo":153,"targetDuration":4,"studyType":23,"phases":155,"briefSummary":156,"conditions":157,"keywords":4,"overallStatus":35,"whyStopped":4,"lastUpdateSubmitDate":158,"lastUpdatePostDateStruct":159,"startDateStruct":161,"completionDateStruct":163,"leadSponsor":165,"locationsCount":47},"100553052","digital-psychological-intervention-for-pediatric-functional-abdominal-pain-disorders-in-primary-care-100553052","NCT06481072","Digital Psychological Intervention for Pediatric Functional Abdominal Pain Disorders in Primary Care","Digital Psychological Intervention for Pediatric Functional Abdominal Pain Disorders Through a Collaborative Pathway Between Primary- and Specialist Pediatric Care: A Randomized Clinical Trial","FAPD","Inclusion Criteria:\n\n* Eligible participants are children and young people aged 8-14.\n* Diagnosed with functional abdominal pain disorders by their physician.\n* Diagnosed at one of the participating primary care health centres.\n\nExclusion Criteria:\n\n* Children and young people with scores above the clinical cut-off on the Revised Child Anxiety and Depression Scale (RCADS).\n* Children who do not follow the mainstream Swedish National Curriculum due to learning disabilities.","14 Years",{"count":154,"type":22},300,[25],"The project involves researching two psychological treatments for functional abdominal pain in children. The treatments will be offered to children as an early intervention, at primary care level. The study will aim to find out if the treatments are effective and which children the different treatments are effective for.",[31],"2024-06-25",{"date":160,"type":39},"2024-07-01",{"date":162,"type":39},"2024-04-01",{"date":164,"type":22},"2026-12-31",{"name":166,"class":46},"Göteborg University"]