[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"functional-capacity\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:functional-capacity":32},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,13,0,[8,54,81,107,134,164,190,220,247,271,311,336,361],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":4,"eligibilityCriteria":15,"healthyVolunteers":16,"sex":17,"minAge":18,"maxAge":4,"enrollmentInfo":19,"targetDuration":4,"studyType":22,"phases":23,"briefSummary":25,"conditions":26,"keywords":33,"overallStatus":41,"whyStopped":4,"lastUpdateSubmitDate":42,"lastUpdatePostDateStruct":43,"startDateStruct":46,"completionDateStruct":48,"leadSponsor":50,"locationsCount":53},"100643588","strength-for-caregiving-100643588",false,"NCT07615205","Strength for Caregiving","Strength for Caregiving - A Nutrition Coaching Model to Support Caregivers' Wellbeing and Functional Ability","Inclusion Criteria:\n\n* Born in 1961 or earlier (i.e. aged over 65 years)\n* Adequate Finnish language skills\n* Able to give informed written consent\n* Acting as a caregiver (with or without a formal caregiver contract) in the areas of Pori, Rauma, or Kankaanpää\n* Normal cognition (participants with an MMSE score below 24 will be assessed by the responsible physician)\n\nExclusion Criteria:\n\n* Serious acute illness or inability to act as an informal caregiver\n* A condition, ailment, or underlying health risk that is poorly controlled and that participation in the study could exacerbate, or a terminal illness (Consultation of the doctor in charge, if necessary, in unclear cases)\n* Born in 1961 or later (i.e. aged under 65 years)\n* Substance abuse based on the AUDIT-C score (consultation of the doctor in charge)",true,"ALL","65 Years",{"count":20,"type":21},100,"ESTIMATED","INTERVENTIONAL",[24],"NA","The goal of this single-arm pre-post study is to promote elderly (≥ 65 years) family caregivers' dietary habits, well-being and functional capacity through comprehensive nutritional guidance. The main goals of the project are to:\n\n* Improve the well-being, resilience, and functional capacity of the participating family caregivers through the comprehensive nutritional counseling implemented as part of the project.\n* Create a nutrition counseling model that promotes the well-being and coping of family caregivers and can also be utilized in well-being services counties after the project concludes.\n* Produce up-to-date and practical nutrition materials for family caregivers.\n\nThe project participants will participate in two individual nutrition counselling sessions and three group nutrition counseling sessions over a period of ten months.\n\nResearchers will compare the results of the participants' baseline and final measurements to see if nutrition counseling is effective in improving family caregivers' well-being, resilience, and functional capacity.",[27,28,29,30,31,32],"Mental Well-being","Muscle Strengh","Dietary Habits","Quality of Life","Nutritional Status","Functional Capacity",[34,35,36,37,38,39,40],"Nutrition","Caregiver","mental well-being","Functional capacity","Quality of life","Nutritional counseling","Intervention","NOT_YET_RECRUITING","2026-06-04",{"date":44,"type":45},"2026-06-08","ACTUAL",{"date":47,"type":21},"2026-09",{"date":49,"type":21},"2027-11",{"name":51,"class":52},"Susanna Kunvik","OTHER",1,{"id":55,"slug":56,"hasResults":11,"nctId":57,"briefTitle":58,"officialTitle":59,"acronym":4,"eligibilityCriteria":60,"healthyVolunteers":11,"sex":17,"minAge":61,"maxAge":62,"enrollmentInfo":63,"targetDuration":4,"studyType":65,"phases":4,"briefSummary":66,"conditions":67,"keywords":4,"overallStatus":71,"whyStopped":4,"lastUpdateSubmitDate":72,"lastUpdatePostDateStruct":73,"startDateStruct":75,"completionDateStruct":77,"leadSponsor":79,"locationsCount":53},"100627689","tb-type-and-spirometry-result-vs-functional-capacity-based-on-6mwt-in-people-with-post-tb-lung-disease-100627689","NCT07451899","TB Type and Spirometry Result vs. Functional Capacity Based on 6MWT in People With Post-TB Lung Disease","Correlation Between Types of Tuberculosis, Spirometry Result, and Functional Capacity Based on the 6-Minute Walk Test (6MWT) in Adolescents With Post-Tuberculosis Lung Disease.","Inclusion Criteria:\n\n* Adolescents (10-18 year old)\n* Diagnosed with post tuberculosis lung disease by pediatrician\n* Capable of performing the 6MWT\n\nExclusion Criteria:\n\n* Diagnosed with another lung disease\n* Having physical limitations that hinder the 6MWT","10 Years","18 Years",{"count":64,"type":21},20,"OBSERVATIONAL","Post-Tuberculosis Lung Disease (PTLD) is defined as chronic respiratory impairment due to previous pulmonary TB. Children recovering from pulmonary TB undergo ongoing respiratory health challenges, including more frequent respiratory symptoms, reduced lung volumes, and a threefold higher rate of pulmonary dysfunction compared to healthy children. These conditions could lead to long-term health consequences such as difficulties in performing daily activities. Pulmonary function impairment in PTLD includes approximately 10% of patients losing more than 50% of lung function. Adolescents who have undergone TB treatment often experience pulmonary function impairment and reduced physical capacity. This aims of this study is to analyze the correlation between type of tuberculosis, spirometry result, and functional capacity in adolescents with post-tuberculosis lung disease.\n\nThis study is an analytical observational study with a cross-sectional approach. This study is conducted at Department of Physical Medicine and Rehabilitation, Hasan Sadikin Hospital, Bandung, starting in March until May 2026. Inclusion criteria including: adolescents (10-18 year old), and diagnosed with post tuberculosis lung disease by pediatrician, and capable of performing the 6MWT. The participants with post TB lung disease will undergo spirometry and functional capacity assessment using the 6-minute walk test (6MWT). Outcomes include spirometry result and functional capacity using 6MWT.",[68,69,32,70],"Post Tuberculosis","Lung Disease","Spirometry","RECRUITING","2026-05-09",{"date":74,"type":45},"2026-05-12",{"date":76,"type":45},"2026-03-01",{"date":78,"type":21},"2026-05-31",{"name":80,"class":52},"Universitas Padjadjaran",{"id":82,"slug":83,"hasResults":11,"nctId":84,"briefTitle":85,"officialTitle":86,"acronym":4,"eligibilityCriteria":87,"healthyVolunteers":11,"sex":17,"minAge":88,"maxAge":89,"enrollmentInfo":90,"targetDuration":4,"studyType":65,"phases":4,"briefSummary":92,"conditions":93,"keywords":95,"overallStatus":41,"whyStopped":4,"lastUpdateSubmitDate":98,"lastUpdatePostDateStruct":99,"startDateStruct":101,"completionDateStruct":103,"leadSponsor":105,"locationsCount":4},"100628077","prehabilitation-to-enhance-preoperative-function-in-elderly-undergoing-abdominal-malignancy-surgery-100628077","NCT07456943","Prehabilitation to Enhance Preoperative Function in Elderly Undergoing Abdominal Malignancy Surgery","Prehabilitation to Enhance Preoperative Function in Elderly Undergoing Abdominal Malignancy Surgery: A Prospective Study at Siriraj Hospital","Inclusion Criteria:\n\n* Diagnosed with intraabdominal malignancy (e.g., colorectal, esophageal, gastric, pancreatic, hepatic, biliary tract, urinary bladder, or endometrial malignancies).\n* Schedules for elective major surgery and formally enrollment in the ERAS program at Siriraj Hospital. (at Siriraj Hospital, patients scheduled for pre-specific elective major surgeries are enrolled into the ERAS program as individual hospital protocols for each ERAS module. All patients are informed about the ERAS program by their surgical team.)\n* Referred to the SiPAP center for prehabilitation in accordance with the ERAS preoperative protocol, with a minimum preoperative time of 14 days before the scheduled surgery date.\n* Able to understand the study protocol and provide written informed consent.\n\nExclusion Criteria:\n\n* Have emergency surgery\n* Reschedule the surgery for an earlier date, allowing less than 14 days for prehabilitation.\n* Severe cardiopulmonary or musculoskeletal conditions that contraindicate exercise (e.g., unstable angina, decompensated heart failure, severe COPD, or orthopedic disability).\n* Cognitive impairment or psychiatric illness precluding participation in prehabilitation.\n* Refusal to participate.\n* Inability to comply with the protocol.","60 Years","90 Years",{"count":91,"type":21},110,"The goal of this observational study is to evaluate the effectiveness of the multimodal prehabilitation program at the Siriraj Integrated Preoperative and Prehabilitation Center (SiPAP) on improving preoperative walking capacity and functional status in patients undergoing elective intraabdominal cancer surgery. The main question it aims to answer is:\n\n\\- Does the prehabilitation program lead to a significant change in 6-minute walk distance (6MWD) at preoperative admission as compared to at baseline assessment? Participants will receive the structured multimodal prehabilitation program, which represents the standard of care for patients in the ERAS protocol at the study site. Outcomes will be measured at preoperative admission and at 1 and 3 months after surgery.",[94,32],"Prehabilitation",[94,37,96,97],"Preoperative care","Abdominal cancer surgery","2026-04-22",{"date":100,"type":45},"2026-04-28",{"date":102,"type":21},"2026-05",{"date":104,"type":21},"2027-12",{"name":106,"class":52},"Siriraj Hospital",{"id":108,"slug":109,"hasResults":11,"nctId":110,"briefTitle":111,"officialTitle":112,"acronym":113,"eligibilityCriteria":114,"healthyVolunteers":11,"sex":17,"minAge":18,"maxAge":4,"enrollmentInfo":115,"targetDuration":4,"studyType":22,"phases":117,"briefSummary":118,"conditions":119,"keywords":4,"overallStatus":71,"whyStopped":4,"lastUpdateSubmitDate":125,"lastUpdatePostDateStruct":126,"startDateStruct":128,"completionDateStruct":130,"leadSponsor":132,"locationsCount":53},"100587245","effect-of-micronized-creatine-monohydrate-on-muscle-mass-strength-and-performance-in-older-adults-submitted-to-total-knee-arthroplasty-100587245","NCT06925880","Effect of Micronized Creatine Monohydrate on Muscle Mass, Strength and Performance in Older Adults Submitted to Total Knee Arthroplasty","Efficacy of Supplementation With Micronized Creatine Monohydrate in the Recovery of Muscle Mass, Muscle Strength and Functional Capacity in Older Adults Operated on for Total Knee Arthroplasty: Randomized Clinical Trial","CREAR","Inclusion Criteria:\n\n* Persons 65 years of age or older who have been operated on for the first time for total knee arthroplasty,\n* who are undergoing an outpatient rehabilitation program according to standard clinical practice,\n* who sign the informed consent form.\n\nExclusion Criteria:\n\n* Chronic renal disease at stage G3b or higher or glomerular filtration rate \\\u003C30 ml\u002Fmin\u002F1.73m2.\n* Hepatic insufficiency, cirrhosis.\n* Neuromuscular and neurodegenerative diseases (amyotrophic lateral sclerosis, multiple sclerosis, muscular dystrophy, myasthenia gravis, Parkinson's disease, etc.).\n* Severe or very severe chronic obstructive pulmonary disease (COPD) (GOLD III-IV).\n* Moderate or severe chronic heart failure (NYHA 3-4).\n* Central sensitivity syndrome (fibromyalgia and chronic fatigue syndrome).\n* Moderate or severe cognitive impairment (GDS≥4).\n* Moderate-severe dependence for basic activities of daily living (preintervention Barthel index \\\u003C60 points).\n* Hemiparesis, amputation or malformation of any limb.\n* Consumption of creatine monohydrate supplements in the last 6 months.",{"count":116,"type":21},262,[24],"Double-blind randomized placebo-controlled clinical trial with two parallel arms. The main objective is to evaluate the efficacy and safety of creatine supplementation in older adults who have been operated on for total knee arthroplasty and undergoing a usual rehabilitation program. The intervention will consist of daily creatine monohydrate supplementation for 12 weeks. The intervention will start after surgery with a loading dose of 20g\u002Fday for 1 week and then continue with a maintenance dose of 5g\u002Fday for 11 weeks.\n\nMain outcome mesures included muscle mass, muscle strenght, sarcopenia, frailty, functional capacity and physical performance and will be assessed at baseline, 3 and 6 months follow-up.",[120,121,32,122,123,124],"Sarcopenia in Elderly","Frailty at Older Adults","Creatine Supplementation","Arthroplasties, Knee Replacement","Physical Performance","2026-03-25",{"date":127,"type":45},"2026-03-30",{"date":129,"type":45},"2025-06-10",{"date":131,"type":21},"2027-10-31",{"name":133,"class":52},"Consorci Sanitari del Maresme",{"id":135,"slug":136,"hasResults":11,"nctId":137,"briefTitle":138,"officialTitle":139,"acronym":4,"eligibilityCriteria":140,"healthyVolunteers":11,"sex":17,"minAge":141,"maxAge":4,"enrollmentInfo":142,"targetDuration":4,"studyType":22,"phases":144,"briefSummary":145,"conditions":146,"keywords":151,"overallStatus":41,"whyStopped":4,"lastUpdateSubmitDate":155,"lastUpdatePostDateStruct":156,"startDateStruct":158,"completionDateStruct":160,"leadSponsor":162,"locationsCount":53},"100622301","the-effects-of-manual-therapy-on-the-spatiotemporal-gait-characteristics-in-patients-with-chronic-obstructive-pulmonary-disease-100622301","NCT07381842","The Effects of Manual Therapy on the Spatiotemporal Gait Characteristics in Patients With Chronic Obstructive Pulmonary Disease","An Investigation of the Effects of Manual Therapy on the Spatiotemporal Gait Characteristics in Patients With Chronic Obstructive Pulmonary Disease","Inclusion Criteria:\n\n* Age 40 years or older\n* Clinically stable for at least the past 4 weeks\n* Classified as GOLD stage 1, 2, or 3 according to the Global Initiative for Chronic Obstructive Pulmonary Disease (GOLD) airflow limitation classification\n* Classified as group A, B, or E according to the GOLD ABE assessment tool\n\nExclusion Criteria:\n\n* Use of walking assistive devices\n* Receiving long-term oxygen therapy\n* Presence of additional orthopedic, neuromuscular, neurological, or cardiac conditions that may affect gait and balance\n* History of lung cancer, sarcoidosis, tuberculosis, and\u002For lung surgery\n* Presence of musculoskeletal conditions such as fibromyalgia, rheumatoid arthritis, or osteoarthritis\n* Presence of a known mental or cognitive impairment","40 Years",{"count":143,"type":21},40,[24],"The primary aim of this study is to investigate the effects of manual therapy on spatiotemporal characteristics of gait and gait variability, functional exercise capacity, and pulmonary function in patients with chronic obstructive pulmonary disease (COPD).\n\nThe secondary aims of the study are to determine the effects of manual therapy on balance, respiratory muscle strength, quality of life, physical activity, symptom severity, accessory respiratory muscle activation, peripheral muscle strength, chest wall mobility, dysfunctional breathing, pain, and posture.",[147,148,149,150,32],"COPD (Chronic Obstructive Pulmonary Disease)","Manuel Therapy","Gait Biomechanics","Muscle Energy Technique",[152,153,154],"COPD","Gait","Manuel therapy","2026-01-26",{"date":157,"type":45},"2026-02-02",{"date":159,"type":21},"2026-02-08",{"date":161,"type":21},"2028-01-08",{"name":163,"class":52},"Hacettepe University",{"id":165,"slug":166,"hasResults":11,"nctId":167,"briefTitle":168,"officialTitle":169,"acronym":4,"eligibilityCriteria":170,"healthyVolunteers":11,"sex":17,"minAge":62,"maxAge":171,"enrollmentInfo":172,"targetDuration":4,"studyType":22,"phases":173,"briefSummary":174,"conditions":175,"keywords":4,"overallStatus":41,"whyStopped":4,"lastUpdateSubmitDate":181,"lastUpdatePostDateStruct":182,"startDateStruct":184,"completionDateStruct":186,"leadSponsor":188,"locationsCount":53},"100617354","effects-of-expiratory-muscle-training-added-to-pulmonary-rehabilitation-in-patients-with-bronchiectasis-100617354","NCT07317531","Effects of Expiratory Muscle Training Added to Pulmonary Rehabilitation in Patients With Bronchiectasis","Effects of Expiratory Muscle Training Added to Pulmonary Rehabilitation on Pulmonary Function, Respiratory Muscle Strength, and Functional Capacity in Patients With Bronchiectasis","Inclusion Criteria:\n\n* Age between 18 and 70 years\n\n  * Clinical diagnosis of non-cystic fibrosis bronchiectasis\n  * Stable disease status\n  * Follow-up at the Pulmonary Rehabilitation Unit of University of Health Sciences Süreyyapaşa Chest Diseases and Thoracic Surgery Training and Research Hospital\n  * Ability to understand and comply with the study procedures\n  * Provided written informed consent\n\nExclusion Criteria:\n\n* Acute exacerbation within the last 3 months\n* Diagnosis of cystic fibrosis-related bronchiectasis\n* Presence of severe cardiac, neurological, or orthopedic diseases that may interfere with exercise training\n* Cognitive impairment, lack of cooperation, or communication difficulties\n* Any medical condition contraindicating participation in pulmonary rehabilitation or expiratory muscle training","70 Years",{"count":143,"type":21},[24],"This randomized, single-blind, parallel-group controlled trial aims to investigate the effects of expiratory muscle training added to standard pulmonary rehabilitation on respiratory muscle strength, pulmonary function, cough effectiveness, exercise capacity, dyspnea perception, and quality of life in patients with non-cystic fibrosis bronchiectasis. Eligible patients aged 18-70 years with stable disease will be randomly assigned to either a pulmonary rehabilitation-only group or a pulmonary rehabilitation combined with expiratory muscle training group. Outcomes will be assessed at baseline and after completion of the intervention period.",[176,177,178,179,32,180],"Bronchiectasis Adult","Expiratory Muscle Training","Pulmonary Rehabilitation","Lung Function Tests","Respiratory Muscle Strength","2026-01-02",{"date":183,"type":45},"2026-01-05",{"date":185,"type":21},"2026-02-01",{"date":187,"type":21},"2027-03-01",{"name":189,"class":52},"Istanbul Demiroglu Bilim University",{"id":191,"slug":192,"hasResults":11,"nctId":193,"briefTitle":194,"officialTitle":194,"acronym":4,"eligibilityCriteria":195,"healthyVolunteers":11,"sex":196,"minAge":197,"maxAge":198,"enrollmentInfo":199,"targetDuration":4,"studyType":22,"phases":200,"briefSummary":201,"conditions":202,"keywords":207,"overallStatus":71,"whyStopped":4,"lastUpdateSubmitDate":211,"lastUpdatePostDateStruct":212,"startDateStruct":214,"completionDateStruct":216,"leadSponsor":218,"locationsCount":53},"100596961","water-based-burpee-exercises-on-functional-capacity-in-poste-menopausal-women-after-thyroidectomy-100596961","NCT07052279","Water Based Burpee Exercises on Functional Capacity in Poste-menopausal Women After Thyroidectomy","Inclusion Criteria:\n\n* Adults aged 54 ± 4 years .\n\n  * Post-menopausal women after tyhroidectomy\n  * Body mass index (BMI) ≥ 30 kg\u002Fm².\n  * Absence of osteoarticular dysfunctions in the lower limbs.\n  * No personal history of cardiovascular disease\n  * No water trauma\n  * Non-smokers\n\nExclusion Criteria:\n\n* History of Cardiovascular disorders.\n\n  * Severe osteoarticular dysfunctions.\n  * Presence of Water panic.\n  * Participation in another clinical trial within the last 30 days.\n  * Neurologic and psychiatric disorders (spina bifida, cerebral palsy, anorexia nervosa, known autism spectrum disorders).","FEMALE","50 Years","54 Years",{"count":143,"type":21},[24],"Skeletal muscle mass plays an important role with both metabolism and functional capacity. It is well established that the aging process leads to a significant decline in both muscle mass and strength which is associated with frailty , an increased risk of falls and decreased physical fitness and function In this context, high-load resistance training has been shown to reduce the risk of falls and increase strength and functional capacity in middle-aged and\u002For elderly individuals.\n\nAquatic exercise is one method that has previously been shown to improve muscle strength, balance, and coordination in those of advancing age Although the evidence supports the effectiveness of both water-based burpee exercise in middle-aged and elderly individuals, has, to our knowledge, never been investigated. Thus, the objective of this study was to assess the long-term effect of water-based burpee exercises",[203,204,32,205,206],"Burpee Exercise","Water Exercises","Postmenopausal","Thyroidectomy",[208,209,210],"burpee exercises","postmenopausal","thyroidectomy","2025-11-15",{"date":213,"type":45},"2025-11-19",{"date":215,"type":45},"2025-09-01",{"date":217,"type":21},"2025-11-30",{"name":219,"class":52},"Al-Zaytoonah University of Jordan",{"id":221,"slug":222,"hasResults":11,"nctId":223,"briefTitle":224,"officialTitle":224,"acronym":4,"eligibilityCriteria":225,"healthyVolunteers":11,"sex":17,"minAge":62,"maxAge":18,"enrollmentInfo":226,"targetDuration":4,"studyType":65,"phases":4,"briefSummary":228,"conditions":229,"keywords":233,"overallStatus":71,"whyStopped":4,"lastUpdateSubmitDate":238,"lastUpdatePostDateStruct":239,"startDateStruct":241,"completionDateStruct":243,"leadSponsor":245,"locationsCount":53},"100604668","the-effect-of-body-weight-on-physical-activity-level-functional-capacity-balance-and-quality-of-life-in-individuals-with-type-2-diabetes-mellitus-100604668","NCT07152509","The Effect of Body Weight on Physical Activity Level, Functional Capacity, Balance, and Quality of Life in Individuals With Type 2 Diabetes Mellitus","Inclusion Criteria:\n\n* Having a diagnosis of Type 2 Diabetes Mellitus for at least 1 year\n* Being between 18 and 65 years of age\n* Having an HbA1c value between 6.5% and 11% at the time of diagnosis\n* No cognitive or mental problems\n* Ability to walk independently\n* Willingness to participate in the study\n\nExclusion Criteria:\n\n* Presence of uncontrolled cardiovascular and pulmonary disease\n* Presence of vertigo or various vestibular system disorders\n* Presence of severe neurological or respiratory disease\n* History of stroke or myocardial infarction\n* Presence of a major musculoskeletal problem\n* Presence of chronic renal failure\n* Presence of diabetic ulcer or neuropathy\n* Pregnancy\n* Presence of hemolytic or renal anemia\n* Presence of serious visual, hearing, or speech impairments leading to lack of cooperation",{"count":227,"type":21},50,"This study aims to investigate the effects of body weight on physical activity level, functional capacity, balance, and quality of life in patients with type 2 diabetes mellitus (T2DM). A total of 50 volunteer patients who meet the inclusion criteria will be recruited from the Internal Medicine and Nutrition outpatient clinics of Bezmialem Vakıf University Hospital.\n\nParticipants will be prospectively evaluated through face-to-face interviews. Assessments will include body composition analysis (Omron Body Composition Monitor), waist-to-hip ratio, lower extremity muscle strength (Muscle Hand-Held Dynamometer), grip strength (Hand Grip Dynamometer), physical activity level (International Physical Activity Questionnaire-Short Form), functional capacity (6-Minute Walk Test), balance (Biodex Balance System), clinical balance (Berg Balance Scale), and quality of life (Nottingham Health Profile).\n\nAll statistical analyses will be performed using IBM SPSS Statistics 20. With this study, we aim to comprehensively evaluate multiple parameters in individuals with T2DM and investigate their interrelationships, thereby contributing to the current body of knowledge in the literature.",[230,231,32,232],"Type 2 Diabetes Mellitus (T2DM)","Body Mass Index","Balance",[234,235,236,237],"quality of life","type 2 diabetes mellitus","body mass index","physical activity","2025-08-26",{"date":240,"type":45},"2025-09-03",{"date":242,"type":45},"2025-08-15",{"date":244,"type":21},"2025-10-15",{"name":246,"class":52},"Bezmialem Vakif University",{"id":248,"slug":249,"hasResults":11,"nctId":250,"briefTitle":251,"officialTitle":251,"acronym":4,"eligibilityCriteria":252,"healthyVolunteers":11,"sex":17,"minAge":253,"maxAge":61,"enrollmentInfo":254,"targetDuration":4,"studyType":22,"phases":255,"briefSummary":256,"conditions":257,"keywords":4,"overallStatus":71,"whyStopped":4,"lastUpdateSubmitDate":262,"lastUpdatePostDateStruct":263,"startDateStruct":265,"completionDateStruct":267,"leadSponsor":269,"locationsCount":53},"100601608","effect-of-incentive-respiratory-training-on-pulmonary-functions-and-functional-capacity-in-children-with-b-thalassemia-major-100601608","NCT07112703","Effect of Incentive Respiratory Training on Pulmonary Functions and Functional Capacity in Children With B-thalassemia Major","Inclusion Criteria:\n\n1. Diagnosed as thalassemia \\& subjected to blood transfusion\n2. Their age range from 6 to 10 years old\n3. Both sexes, male and female, will participate.\n4. Subjects are able to follow simple verbal commands or instructions included in the procedures.\n\nExclusion Criteria:\n\n1. Children with mental retardation or any other disability .\n2. Children with visual or hearing defects.\n3. Children with cardiovascular, chest pulmonary, and heart diseases.\n4. Children with any postoperative cardiovascular, chest pulmonary, and heart conditions.","6 Years",{"count":227,"type":21},[24],"The study was done to:\n\n1. Investigate the effect of respiratory training on functional lung capacity and\n2. To detect the effect of respiratory training on pulmonary functions in children with β-thalassemia major.\n3. To detect the level of oxygen saturation and heart rate during and after blood transfusion in children with β-thalassemia major.",[258,259,32,260,261],"Incentive Spirometer","Pulmonary Function","Child, Only","Thalassemia Major","2025-08-02",{"date":264,"type":45},"2025-08-08",{"date":266,"type":45},"2025-04-07",{"date":268,"type":21},"2025-10-08",{"name":270,"class":52},"Rawan Mohammed Khairy Mostafa Elsawy",{"id":272,"slug":273,"hasResults":11,"nctId":274,"briefTitle":275,"officialTitle":275,"acronym":4,"eligibilityCriteria":276,"healthyVolunteers":16,"sex":17,"minAge":62,"maxAge":4,"enrollmentInfo":277,"targetDuration":279,"studyType":65,"phases":4,"briefSummary":280,"conditions":281,"keywords":294,"overallStatus":71,"whyStopped":4,"lastUpdateSubmitDate":300,"lastUpdatePostDateStruct":301,"startDateStruct":303,"completionDateStruct":305,"leadSponsor":307,"locationsCount":310},"100589754","apple-health-study-100589754","NCT06958523","Apple Health Study","Inclusion Criteria:\n\n* Be at least 18 years old (at least 19 years old in Alabama and Nebraska, at least 21 years old in Puerto Rico);\n* Live in the United States of America;\n* Have an iPhone;\n* Have installed Apple Research app on your iPhone;\n* Be comfortable communicating in written and spoken English;\n* Be willing and able to provide informed consent to participate in the Study.\n\nExclusion Criteria:\n\n* Share your iCloud account, iPhone, or devices that collect health data such as Apple Watch with anyone else, because it could result in sharing another person's health information with the Study, making it challenging for researchers to use your information.",{"count":278,"type":21},500000,"5 Years","The Apple Health Study aims to build a diverse and inclusive group of participants to help researchers advance our understanding of how signals and information collected from apps and devices relate to health and may be used to predict, detect, monitor, and manage changes in health.\n\nTo enroll, US residents who have an iPhone can download the Apple Research app from the App Store and go through the introduction and informed consent for the Apple Health Study. This study is fully remote, and all are invited to enroll if the eligibility criteria are met.\n\nParticipants will be asked to complete tasks and surveys, using their iPhone and Apple Research app which include:\n\n* Selecting the types of data they would like to share with the study such as health and sensor data\n* Completing tasks and surveys including areas such as personal demographic information, personal medical history, family history, and social determinants of health",[282,283,284,285,286,287,288,289,32,290,291,292,293],"Mental Health","Sleep","Exercise","Hormones","Metabolic Health","Hearing","Aging","Lifestyle Factors","Neurological Conditions","General Health","Wellbeing","Women's Health",[275,295,296,297,298,299],"Large Scale Digital Study","Digital Biomarkers","Research App","Apple Research App","iPhone","2025-07-24",{"date":302,"type":45},"2025-07-29",{"date":304,"type":45},"2025-02-12",{"date":306,"type":21},"2030-02",{"name":308,"class":309},"Apple Inc.","INDUSTRY",2,{"id":312,"slug":313,"hasResults":11,"nctId":314,"briefTitle":315,"officialTitle":316,"acronym":4,"eligibilityCriteria":317,"healthyVolunteers":11,"sex":196,"minAge":318,"maxAge":171,"enrollmentInfo":319,"targetDuration":4,"studyType":65,"phases":4,"briefSummary":321,"conditions":322,"keywords":4,"overallStatus":41,"whyStopped":4,"lastUpdateSubmitDate":327,"lastUpdatePostDateStruct":328,"startDateStruct":330,"completionDateStruct":332,"leadSponsor":334,"locationsCount":53},"100591143","muscle-oxygen-saturation-and-functional-capacity-in-breast-cancer-survivors-100591143","NCT06976593","Muscle Oxygen Saturation and Functional Capacity in Breast Cancer Survivors","Analysis of Muscle Oxygen Saturation and Functional Variables During Physical Performance Tests in Breast Cancer Survivors","Inclusion Criteria:\n\n* Women aged 30 to 70 years\n* Clinical history of breast cancer treatment (at least 6 months prior)\n* Completed primary cancer treatment\n* Ability to perform physical tests\n* Signed informed consent\n\nExclusion Criteria:\n\n* Recurrence or metastasis\n* Severe cardiopulmonary or musculoskeletal disease\n* Neurological or cognitive limitations\n* Ongoing oncological treatment","30 Years",{"count":320,"type":21},30,"This cross-sectional observational study aims to assess muscle oxygen saturation (SmO2) in the intercostal, quadriceps, and triceps surae muscles using near-infrared spectroscopy (NIRS) during functional exercise tests in breast cancer survivors. Participants will be grouped based on their previous cancer treatment: hormonal therapy only or hormonal therapy combined with chemotherapy. Functional performance will be evaluated through the 6-Minute Walk Test, 30-Second Sit-to-Stand Test, and a submaximal treadmill test. The study will analyze differences in muscle oxygenation and performance between groups and explore associations with other functional and clinical parameters.",[323,324,325,284,30,32,326],"Breast Cancer Survivorship","Muscle Oxygenation","Near-infrared Spectroscopy","Hormonal Therapy","2025-05-13",{"date":329,"type":45},"2025-05-16",{"date":331,"type":21},"2025-05-05",{"date":333,"type":21},"2025-05-31",{"name":335,"class":52},"University of Extremadura",{"id":337,"slug":338,"hasResults":11,"nctId":339,"briefTitle":340,"officialTitle":341,"acronym":4,"eligibilityCriteria":342,"healthyVolunteers":16,"sex":17,"minAge":62,"maxAge":18,"enrollmentInfo":343,"targetDuration":4,"studyType":65,"phases":4,"briefSummary":345,"conditions":346,"keywords":347,"overallStatus":41,"whyStopped":4,"lastUpdateSubmitDate":352,"lastUpdatePostDateStruct":353,"startDateStruct":355,"completionDateStruct":357,"leadSponsor":359,"locationsCount":53},"100580609","6-minute-walk-test-assessment-via-mobile-app-100580609","NCT06839521","6-Minute Walk Test Assessment Via Mobile App","Development, Validity and Reliability of Android Based 6 Minute Walking Test","Inclusion Criteria:\n\n* Not having a disease that prevents walking\n* To be able to use a smartphone\n\nExclusion Criteria:\n\n* Exercise restriction for any reason\n* Pregnancy or any known cardiovascular, pulmonary, neurological, metabolic or haematological disease\n* Having any problem that prevents communication",{"count":344,"type":21},111,"This study aims to develop an Android-based 6-Minute Walk Test (6MWT) application to facilitate quick and efficient functional capacity assessment in clinical settings. The project will be carried out by a multidisciplinary team of software engineers and physiotherapists, with algorithms developed for both indoor and outdoor environments. As GPS signals may be lost indoors, the program will utilize the phone's gyroscope for distance measurement, while GPS signals will be used outdoors. The study will include healthy individuals aged 18-65, without any exercise restrictions. Participants' demographic data will be recorded, and the 6MWT will be conducted according to traditional protocols. During the test, parameters such as heart rate, oxygen saturation, and walking distance will be measured and compared with traditional methods. The Android application will provide auditory and vibration cues at the start and end of the test and will report health data in real-time. The data will be presented as mean ± standard deviation for continuous variables, and the test reliability will be assessed using the test-retest method. Results will be reported as age- and gender-adjusted z-scores for objective functional decline.",[32],[348,349,350,351],"6-Minute Walk Test","Android","Validity","Reliability","2025-04-29",{"date":354,"type":45},"2025-04-30",{"date":356,"type":21},"2025-05-30",{"date":358,"type":21},"2026-05-15",{"name":360,"class":52},"Izmir Democracy University",{"id":362,"slug":363,"hasResults":11,"nctId":364,"briefTitle":365,"officialTitle":366,"acronym":4,"eligibilityCriteria":367,"healthyVolunteers":11,"sex":17,"minAge":62,"maxAge":368,"enrollmentInfo":369,"targetDuration":4,"studyType":22,"phases":371,"briefSummary":372,"conditions":373,"keywords":377,"overallStatus":41,"whyStopped":4,"lastUpdateSubmitDate":380,"lastUpdatePostDateStruct":381,"startDateStruct":383,"completionDateStruct":385,"leadSponsor":387,"locationsCount":53},"100568419","hospital-based-and-home-based-resistance-training-in-adult-congenital-heart-disease-100568419","NCT06680973","Hospital-Based and Home-Based Resistance Training in Adult Congenital Heart Disease","Comparison of the Effects of Hospital-Based and Home-Based Resistance Training in Individuals with Adult Congenital Heart Disease","Inclusion Criteria:\n\n* Diagnosis of congenital heart disease\n* Aged between 18 and 45 years\n* Being informed about the study and providing written consent to participate\n* Clinical stability has been achieved in the patients\n* No changes in ongoing medication treatment that negatively affect clinical stability\n\nExclusion Criteria:\n\n* Having additional cardiovascular, neurological, orthopedic, or any other systemic diseases\n* Being classified as high risk (severe systolic dysfunction, moderate\u002Fsevere elevated pulmonary artery pressure, significant arrhythmic burden, malignant arrhythmia, etc.)\n* Not suitable for cognitive, psychological, and mental assessments\n* Undergoing a surgery other than heart surgery","45 Years",{"count":370,"type":21},33,[24],"Congenital heart disease (CHD) is defined as functional or anatomical abnormalities of the heart and major intrathoracic vessels present at birth. Impaired responses to exercise in individuals with CHD reduce exercise capacity and increase long-term mortality risk. Today, the growing population of adults with congenital heart disease (ACHD) faces chronic issues stemming from congenital abnormalities, along with muscle strength loss and a decline in activities of daily living. Once the planned treatments in this project proposal are implemented and data are obtained (especially if these data support the hypotheses), the treatment protocols applied in this study and their effects will be considered alongside the current treatment plans for individuals with CHD who experience muscle strength loss and disease-related impairment. With new treatment programs, this study aims to reduce disease-related muscle strength loss, improve disease-related outcomes, and enhance quality of life.",[374,375,376,32],"Congenital Heart Diseases","Resistance Training","Muscle Strength",[374,378,379,37],"Resistance training","Muscle strength","2024-11-07",{"date":382,"type":45},"2024-11-08",{"date":384,"type":21},"2025-01-05",{"date":386,"type":21},"2025-11-05",{"name":163,"class":52}]