[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"functional-decline\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:functional-decline":27},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,8,0,[8,49,88,123,159,179,207,236],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":4,"eligibilityCriteria":15,"healthyVolunteers":11,"sex":16,"minAge":17,"maxAge":4,"enrollmentInfo":18,"targetDuration":4,"studyType":21,"phases":22,"briefSummary":24,"conditions":25,"keywords":30,"overallStatus":36,"whyStopped":4,"lastUpdateSubmitDate":37,"lastUpdatePostDateStruct":38,"startDateStruct":41,"completionDateStruct":43,"leadSponsor":45,"locationsCount":48},"100563444","training-community-members-to-be-coaches-to-deliver-the-healthylifetime-program-100563444",false,"NCT06616246","Training Community Members to be Coaches to Deliver the HealthyLifetime Program","Evaluating the Use of Community Members Trained as Health Coaches to Deliver the HealthyLifetimeTM Program","Inclusion Criteria:\n\n* Be at least 30 years of age, with no more than three, uncomplicated chronic conditions and want to learn to take better care of their health.\n* Independent Living Index (ILI) greater than 35. ILI is derived by averaging the outcome measures scores.\n* A score of less than 4 on items related to anxiety and depressive symptoms\n* Have Medicare and\u002For Medicaid insurance.\n* Be able to read, speak, and hear English - but may use glasses or hearing aids, if needed;\n* Tell us their age, date of birth, address, and phone number, and explain their health problems;\n* Have a computer, iPad (Tablet), or Smartphone with an Internet connection, email address, a working camera, and microphone;\n* Be able to use their computer\u002Ftablet to connect to video chat sessions like Zoom in a private space in their home or a private room\n* Are not currently participating in any other studies involving diet, weight management, exercise and\u002For coaching at the current time; and\n* Reside in Michigan.\n\nExclusion Criteria:\n\n* ● Are less than 30 years of age.\n\n  * Have more than three, uncomplicated chronic conditions.\n  * A score of more than 4 on items related to anxiety and depressive symptoms\n  * Do not have Medicare and\u002For Medicaid insurance.\n  * Do not reside in Michigan.\n  * Have a new acute health problem that requires seeing a doctor more than once a month for acute medical treatment.\n  * Have been told their illness is not curable.\n  * Need help remembering their name, date of birth, or health problems.\n  * Cannot use glasses or a hearing aid to see or hear well enough to read materials on the computer or talk to the nurse easily.\n  * Are currently participating in any other studies involving diet, weight management, exercise and\u002For coaching at the current time; and\n  * Do not have, or cannot use, a computer, iPad, or another device with the Internet at home to use Zoom (e.g., internet streaming).","ALL","30 Years",{"count":19,"type":20},300,"ESTIMATED","INTERVENTIONAL",[23],"NA","The goal of this randomized controlled study is to learn if, in addition to nurses, community members can be trained as health coaches to deliver the HealthyLifetime (HL) program to people without complex chronic health conditions, an intervention that provides a short-term and effective health coaching intervention delivered through a virtual platform to improve health, resiliency, and independent self-care to participants who are without complex chronic conditions. The main question it aims to answer is:\n\n• Can Community Health Coaches achieve the same level of competency and outcome as Nurse Health Coaches in participants without complex chronic conditions?",[26,27,28,29],"Health Behaviors","Functional Decline","Chronic Disease","Risk Factors",[31,32,33,34,35],"health coach","health resiliency","independent self-care","community health workers","independent aging","RECRUITING","2026-06-18",{"date":39,"type":40},"2026-06-22","ACTUAL",{"date":42,"type":40},"2025-05-15",{"date":44,"type":20},"2028-12",{"name":46,"class":47},"University of Michigan","OTHER",2,{"id":50,"slug":51,"hasResults":11,"nctId":52,"briefTitle":53,"officialTitle":54,"acronym":55,"eligibilityCriteria":56,"healthyVolunteers":11,"sex":16,"minAge":57,"maxAge":4,"enrollmentInfo":58,"targetDuration":4,"studyType":21,"phases":60,"briefSummary":61,"conditions":62,"keywords":67,"overallStatus":36,"whyStopped":4,"lastUpdateSubmitDate":78,"lastUpdatePostDateStruct":79,"startDateStruct":81,"completionDateStruct":83,"leadSponsor":85,"locationsCount":87},"100633834","multicomponent-prehabilitation-in-older-adults-with-breast-cancer-100633834","NCT07531836","Multicomponent Prehabilitation in Older Adults With Breast Cancer","Effectiveness of a Multicomponent Prehabilitation Program Combined With Biomarker Characterization in Older Adults With Breast Cancer","PREHAB-BC65","Inclusion Criteria:\n\n* Age ≥65 years\n* Diagnosis of cancer requiring elective surgery with curative intent\n* Candidate for prehabilitation program before surgery\n* Ability to walk (with or without assistive devices)\n* Ability to provide informed consent\n\nExclusion Criteria:\n\n* Urgent or emergency surgery\n* Severe cognitive impairment precluding participation in the intervention\n* Severe functional dependency (e.g., bedridden patients)\n* Medical contraindication to physical exercise\n* Life expectancy \\\u003C3 months","65 Years",{"count":59,"type":20},90,[23],"Older adults with breast cancer frequently present with frailty, decreased functional reserve, and increased risk of postoperative complications. Prehabilitation programs have emerged as a promising strategy to improve physical function and clinical outcomes; however, evidence in geriatric oncology remains limited, particularly regarding the role of biological markers in predicting response to such interventions.\n\nThis study aims to evaluate the effectiveness of a multicomponent prehabilitation program in older adults with breast cancer, focusing on functional status, clinical outcomes, and quality of life. In addition, the study seeks to characterize biological markers associated with frailty and treatment response, with the goal of identifying potential predictors of benefit from prehabilitation.\n\nParticipants will undergo a structured prehabilitation intervention including physical exercise, nutritional optimization, and comprehensive geriatric assessment. Clinical, functional, and biomarker data will be collected longitudinally.\n\nThe results of this study may contribute to improving personalized care strategies in geriatric oncology and to identifying patients who are most likely to benefit from prehabilitation programs.",[63,64,65,66,27],"Breast Cancer","Frailty","Sarcopenia","Aging",[68,69,70,71,72,73,74,75,76,77],"Prehabilitation","Geriatric Oncology","Comprehensive Geriatric Assessment","Exercise Intervention","Vivifrail","Older Adults","Biomarkers","Functional Status","Quality of Life","Randomized Controlled Trial","2026-04-13",{"date":80,"type":40},"2026-04-15",{"date":82,"type":40},"2024-12-04",{"date":84,"type":20},"2027-08",{"name":86,"class":47},"Fundacion Miguel Servet",1,{"id":89,"slug":90,"hasResults":11,"nctId":91,"briefTitle":92,"officialTitle":93,"acronym":94,"eligibilityCriteria":95,"healthyVolunteers":11,"sex":16,"minAge":57,"maxAge":4,"enrollmentInfo":96,"targetDuration":4,"studyType":21,"phases":98,"briefSummary":99,"conditions":100,"keywords":104,"overallStatus":113,"whyStopped":4,"lastUpdateSubmitDate":114,"lastUpdatePostDateStruct":115,"startDateStruct":117,"completionDateStruct":119,"leadSponsor":121,"locationsCount":4},"100619164","comprehensive-geriatric-assessment-in-primary-care-100619164","NCT07341061","Comprehensive Geriatric Assessment in Primary Care","Comprehensive Geriatric Assessment in Primary Care for Older Adults Across Levels of Frailty","PC-CGA","Inclusion Criteria:\n\n* Older adult patients receiving care at the Dalhousie Family Medicine Clinic and scheduled to undergo an eCGA as part of routine primary care.\n* Fluent in English and able to respond to interview and questionnaire items.\n* Able to provide informed consent; or, if judged unable to consent, able to provide assent AND has a substitute decision maker (SDM) who is willing to provide informed consent on their behalf.\n* (PAHA sub-study) Enrolled in the main eCGA study, willing to participate in a personalized physical activity- program, and available for follow-up contact.\n\nExclusion Criteria:\n\n* Not scheduled for, or not receiving, an eCGA at the investigator's family medicine clinic.\n* Unable to communicate in English, such that questionnaires and interviews cannot be completed.\n* Unable to provide informed consent and no SDM available or willing to consent on the patient's behalf.\n* (PAHA sub-study) Deemed unsuitable for the physical activity intervention by the treating family physician (e.g., medical or functional condition that, in the physician's judgment, makes participation in light-moderate exercise unsafe).",{"count":97,"type":20},120,[23],"This study evaluates the feasibility and acceptability of implementing the electronic Comprehensive Geriatric Assessment (eCGA) in primary care for adults aged 65 years and older. The study examines how frailty changes over 12 months, how patient self-assessments compare with physician assessments, and how patients perceive the value of the eCGA when used as part of routine care.\n\nThe study also includes an interventional randomized sub-study (PAHA), in which eligible participants receive a personalized physical activity program developed by a Clinical Exercise Physiologist. Participants are randomized to either an immediate-start or delayed-start exercise group, allowing assessment of the effects of a tailored activity intervention on frailty, physical activity participation, and goal attainment.\n\nFindings will inform how eCGA tools and personalized activity interventions can be integrated into primary care to support healthy aging and frailty management.",[64,66,101,102,27,103],"Geriatric Syndromes","Mobility Limitation","Sedentary Lifestyle",[64,105,106,107,108,109,73,110,111,71,112],"eCGA","electronic Comprehensive Geriatric Assessment","Primary Care","Frailty Index","Clinical Frailty Scale","Healthy Aging","Physical Activity Intervention","Geriatric Assessment","NOT_YET_RECRUITING","2026-01-05",{"date":116,"type":40},"2026-01-14",{"date":118,"type":20},"2026-01-12",{"date":120,"type":20},"2029-01-12",{"name":122,"class":47},"Nova Scotia Health Authority",{"id":124,"slug":125,"hasResults":11,"nctId":126,"briefTitle":127,"officialTitle":128,"acronym":129,"eligibilityCriteria":130,"healthyVolunteers":11,"sex":16,"minAge":131,"maxAge":4,"enrollmentInfo":132,"targetDuration":4,"studyType":134,"phases":4,"briefSummary":135,"conditions":136,"keywords":140,"overallStatus":113,"whyStopped":4,"lastUpdateSubmitDate":150,"lastUpdatePostDateStruct":151,"startDateStruct":153,"completionDateStruct":155,"leadSponsor":157,"locationsCount":87},"100615956","a-model-for-continuous-care-of-fragile-patients-100615956","NCT07299344","A Model for Continuous Care of Fragile Patients","Un Modello di Presa in Carico Continua Del Paziente Fragile","AFTER","Inclusion criteria:\n\n* Adult medically fragile patients with one of the following neurological conditions: mild-to-moderate stroke (Rankin ≤ 3), Multiple Sclerosis (EDSS ≤ 6.5), Parkinson's disease or parkinsonisms, neuromuscular diseases; or orthopedic conditions: femur, pelvis, or humerus fracture.\n* Able to walk independently, with or without assistive devices.\n* Adequate cognitive function (MMSE ≥ 24).\n* Patient or caregiver owns and can use a mobile device with internet\u002Fdata connection.\n* Presence of a cognitively capable, cooperative caregiver willing to participate in the study.\n\nExclusion criteria:\n\n* Patients with severe neurological or orthopedic conditions who cannot walk independently, even with assistive devices.\n* Patients with moderate or severe cognitive impairment (MMSE \\\u003C 24).\n* Patients with Barthel Index \\> 60.\n* Patients or caregivers unable to use a mobile device or without internet\u002Fdata connection.\n* Patients without a cooperative, cognitively capable caregiver.","18 Years",{"count":133,"type":20},100,"OBSERVATIONAL","This observational study aims to monitor functional status and identify potential declines in the functioning of medically fragile patients with neurological and\u002For orthopedic conditions, representing an added value for ensuring appropriate patient management. This approach improves system efficiency and supports a proactive strategy that promotes the appropriate use of resources.",[137,138,27,139],"Neurological Disorders","Orthopedic Disorders","Fragile and More Vulnerable",[141,27,142,137,143,144,145,146,147,148,149],"Functional Monitoring","Medically Fragile Patients","Orthopedic Conditions","Rehabilitation","Proactive Care Model","Continuous Patient Management","Rehabilitation Setting","Early Detection of Functional Changes","telemedicine","2025-12-09",{"date":152,"type":40},"2025-12-23",{"date":154,"type":20},"2025-12",{"date":156,"type":20},"2028-06",{"name":158,"class":47},"Azienda Sanitaria Locale CN2 Alba-Bra",{"id":160,"slug":161,"hasResults":11,"nctId":162,"briefTitle":163,"officialTitle":163,"acronym":4,"eligibilityCriteria":164,"healthyVolunteers":11,"sex":16,"minAge":4,"maxAge":4,"enrollmentInfo":165,"targetDuration":4,"studyType":134,"phases":4,"briefSummary":166,"conditions":167,"keywords":4,"overallStatus":113,"whyStopped":4,"lastUpdateSubmitDate":170,"lastUpdatePostDateStruct":171,"startDateStruct":173,"completionDateStruct":175,"leadSponsor":177,"locationsCount":87},"100605673","prevalence-of-anticholinergics-in-geriatric-patients-with-acute-functional-deterioration-100605673","NCT07165574","Prevalence of Anticholinergics in Geriatric Patients With Acute Functional Deterioration","Inclusion Criteria:\n\n* patients seen by the Subacute outpatient geriatric clinic at Aalborg University hospital, Denmark, between 2024 and 2025.\n* Consecutive sampling starting with the most recent patient chart and going backwards.\n* Inclusion is based on chart review and all patients are therefore included consecutively.\n\nExclusion Criteria:\n\n* None",{"count":133,"type":20},"This study investigates the anticholinergic burden on patients seen in the Subacute mobile outpatient geriatric clinic in Aalborg, Denmark, between the years of 2024 and 2025.\n\nThe age demographic in Denmark and multiple other countries is changing rapidly, with more old and very old individuals as a result. As humans become older, they tend to accumulate more illnesses, and the risk of polypharmacy increases. There is a wide selection of medicine that affect the binding of acetylcholine to the muscarinic receptors, which is either the intended function of the pharmacological product or a side effect.\n\nSince there is no built-in feature in computer systems used by doctors to calculate the cumulative anticholinergic burden, it is often not recognized, thus not reflected upon.\n\nThis raises concerns about potential central and peripheral side effects, such as altered mental status, visual disturbances, tachycardia, urinary and fecal retention, dry skin etc.\n\nThe study aims to determine the prevalence of anticholinergics in the last 100 patients seen by the Subacute mobile outpatient geriatric clinic in Aalborg University Hospital. The patients are placed in municipal extended-care facilities. Furthermore, the study will investigate the prevalence of anticholinergic side effects concerning the burden on this population.\n\nThe study is a retrospective chart review of patient charts from the years of 2024 and 2025, analyzing patient characteristics, comorbidities, medication lists, and calculating the anticholinergic burden through the ACB calculator.",[168,27,169],"Frailty in Older Adults","Anticholinergic Syndrome","2025-09-09",{"date":172,"type":40},"2025-09-10",{"date":174,"type":20},"2025-09-01",{"date":176,"type":20},"2027-01-01",{"name":178,"class":47},"Aalborg University Hospital",{"id":180,"slug":181,"hasResults":11,"nctId":182,"briefTitle":183,"officialTitle":184,"acronym":185,"eligibilityCriteria":186,"healthyVolunteers":11,"sex":16,"minAge":57,"maxAge":4,"enrollmentInfo":187,"targetDuration":4,"studyType":134,"phases":4,"briefSummary":189,"conditions":190,"keywords":194,"overallStatus":113,"whyStopped":4,"lastUpdateSubmitDate":199,"lastUpdatePostDateStruct":200,"startDateStruct":201,"completionDateStruct":203,"leadSponsor":205,"locationsCount":4},"100605530","incidence-and-factors-of-functional-decline-after-emergency-department-discharge-in-older-adults-with-falls-100605530","NCT07163715","Incidence and Factors of Functional Decline After Emergency Department Discharge in Older Adults With Falls","Prospective Cohort Study on the Incidence and Associated Factors of Decline in Activities of Daily Living Among Older Adults Discharged From the Emergency Department After a Fall","FALL-ADL","Inclusion Criteria:\n\n* Age ≥ 65 years\n* Presentation to the emergency department with a simple (non-injurious) fall\n* Discharged from the ED without hospitalization\n* Cognitively able to answer online or telephone follow-up interviews\n\nExclusion Criteria:\n\n* Falls due to traumatic events other than simple falls\n* Hospital admission required after the fall\n* Presence of acute confusion, dementia, or other severe cognitive impairment\n* Inability to access online or telephone follow-up during the 30-day study period",{"count":188,"type":20},280,"The goal of this observational study is to learn about changes in activities of daily living (ADL) in older adults after being discharged from the emergency department (ED) following a fall.\n\nThe main questions this study aims to answer are:\n\nHow often do older adults experience a decline in their ability to perform daily activities after being discharged from the ED for a fall? What health or lifestyle factors (such as frailty, medications, physical activity, or fear of falling) are related to this decline? Participants will be 65 years or older, admitted to the ED for a simple fall, and discharged without hospitalization. At the time of their ED visit, participants will be asked questions about their health, medications, activity level, and daily functioning. They will then be contacted online or by phone at 7 days and 30 days after discharge to answer follow-up questions.\n\nThis study will help identify how common functional decline is after falls in older adults discharged from the ED, and which factors may predict higher risk. These findings could help improve follow-up care and prevention strategies for older patients.",[191,192,27,193],"Fall","Daily Activities","Older Adults (65 Years and Older)",[195,196,197,198],"Falls","Decline fictional status","Decline daily activities","Emergency medicine","2025-09-02",{"date":170,"type":40},{"date":202,"type":20},"2025-09-05",{"date":204,"type":20},"2025-12-05",{"name":206,"class":47},"Ege University",{"id":208,"slug":209,"hasResults":11,"nctId":210,"briefTitle":211,"officialTitle":212,"acronym":4,"eligibilityCriteria":213,"healthyVolunteers":11,"sex":16,"minAge":57,"maxAge":4,"enrollmentInfo":214,"targetDuration":4,"studyType":21,"phases":216,"briefSummary":217,"conditions":218,"keywords":221,"overallStatus":36,"whyStopped":4,"lastUpdateSubmitDate":227,"lastUpdatePostDateStruct":228,"startDateStruct":230,"completionDateStruct":232,"leadSponsor":234,"locationsCount":87},"100531849","effects-of-elastic-band-resistance-exercise-on-muscle-strength-and-depression-in-hospitalized-elderly-100531849","NCT06205147","Effects of Elastic Band Resistance Exercise on Muscle Strength and Depression in Hospitalized Elderly.","Effects of Elastic Band Resistance Exercise on Muscle Strength and Depression in Hospitalized Elderly Patients.","Inclusion Criteria:\n\n1. Age of 65 years or older.\n2. Anticipated hospital stay exceeding 7 days.\n3. Able to follow instructions.\n4. Four-limb muscle strength of at least three points, and grip strength measurements with a minimum of 26 kilograms for males and 18 kilograms for females.\n\nExclusion Criteria:\n\n1. This includes individuals with cardiovascular diseases such as acute myocardial infarction, unstable angina, poorly controlled arrhythmias, complete atrioventricular block, acute heart failure, acute myocarditis, acute pericarditis, and other cardiac conditions.\n2. Poorly controlled hypertension, with systolic blood pressure less than 90 mmHg or greater than 200 mmHg under medication.\n3. Individuals hospitalized due to acute neurological injuries or conditions, such as epilepsy, stroke, or Parkinson's disease.\n4. Diagnosed with cognitive impairment or Alzheimer's disease.\n5. Those who require long-term ventilator support and are unable to participate in the program.\n6. Individuals with impaired consciousness who cannot cooperate.\n7. A Glasgow Coma Scale score of less than 12, or inability to correctly answer questions about person, time, place, or follow instructions.",{"count":215,"type":20},62,[23],"With improved a five-day intensive, low-resistance elastic band exercise program to evaluate its effectiveness in improving total muscle mass, upper and lower extremity muscle strength, self-perceived fear of falling, and depression among hospitalized elderly individuals. This study is a random control trial. Data collection includes elderly patient's total muscle mass, upper and lower extremity muscle strength, self-perceived fear of falling, and depression among hospitalized. The total muscle mass and upper and lower extremity muscle strength will be calculated in kilograms.",[219,220,27],"Resistance Exercise","Muscle Weakness",[222,223,224,225,226],"resistance exercise","hospitalized elderly","muscle strength","depression","Functional decline","2025-07-21",{"date":229,"type":40},"2025-07-24",{"date":231,"type":40},"2025-03-05",{"date":233,"type":20},"2025-12-31",{"name":235,"class":47},"National Taiwan University",{"id":237,"slug":238,"hasResults":11,"nctId":239,"briefTitle":240,"officialTitle":241,"acronym":242,"eligibilityCriteria":243,"healthyVolunteers":11,"sex":16,"minAge":131,"maxAge":244,"enrollmentInfo":245,"targetDuration":4,"studyType":21,"phases":246,"briefSummary":247,"conditions":248,"keywords":254,"overallStatus":113,"whyStopped":4,"lastUpdateSubmitDate":265,"lastUpdatePostDateStruct":266,"startDateStruct":268,"completionDateStruct":270,"leadSponsor":272,"locationsCount":87},"100590008","brief-title-the-role-of-nutrition-in-the-rehabilitation-of-patients-with-eating-disorders-after-a-vascular-stroke-100590008","NCT06961825","Brief Title: The Role of Nutrition in the Rehabilitation of Patients With Eating Disorders After a Vascular Stroke.","The Role of Nutrition in the Rehabilitation of Patients With Eating Disorders After a Vascular Stroke: A Randomized Controlled Trial Investigating the Effect of Protein Supplementation on Functional Recovery, Sarcopenia, Osteopenia, and Nutritional Status in Stroke Patients With Hypoalbuminemia.","Nutristroke","Inclusion Criteria:\n\n* Age range: Adults aged 18 to 85 years\n* Diagnosis: Patients diagnosed with a stroke (cerebrovascular accident) within the last 4 to 6 weeks\n* Serum albumin levels: Patients with low serum albumin levels (\\\u003C 3.5 g \u002F dL)\n* Nutritional intervention requirement: Patients who require nutritional intervention to support rehabilitation and nutrition\n* Informed consent: Patients who have completed the consent form for participation in the study and acceptance of the intervention\n\nExclusion Criteria:\n\n* Severe infections or serious cardiopulmonary conditions: Patients with severe infections or serious cardiopulmonary conditions requiring immediate medical intervention, which may affect nutrition and rehabilitation\n* Comorbidities: Patients with comorbid conditions such as renal or liver disease\n* History of stroke or neurological conditions: Patients with a history of stroke or other neurological conditions who do not meet the criteria for rehabilitation\n* Severe mental or psychological conditions: Patients with severe mental or psychological conditions who are unable to understand or consent to participation in the study","85 Years",{"count":133,"type":20},[23],"Brief Summary: The main objective of this thesis is to investigate the role of nutrition - specifically the administration of protein supplements (single dose and double dose) - in the rehabilitation of stroke patients with low albumin levels in relation to sarcopenia, osteopenia and functional recovery indices. The study will follow a randomized controlled trial design, incorporating clinical observation, analysis of biochemical markers, and assessment of physical and functional parameters. Participants will be randomly assigned to one of the three groups: (1) Group 1, receiving no protein supplementation (control group), (2) Group 2, receiving a single dose of protein supplement and (3) Group 3, receiving a double dose of protein supplement. The intervention will last for at least six weeks or until the biochemical markers of albumin normalize and the patient resumes regular oral intake. Biochemical assessment with be conducted through regular nutritional evaluations including measurement of serum albumin, prealbumin, C - reactive protein, creatinine, blood glucose and glycosylated hemoglobin (HbA1c), urea, electrolytes, urine albumin and additional inflammatory markers. Bone density will be assessed using DEXA, MBSR and hip measurements to determine the potential improvements resulting from the intervention. Muscle mass will be evaluated using whole - body DEXA analysis, while muscle strength and mobility will be assessed through grip strength tests and fine gait assessments. Functional recovery will be evaluated usings standardized tools for activities of daily living (Barthel Index), mental state (Geriatric Depression Scale) and quality of life (SF - 36), as well as mobility and walking tests such as the Timed Up and Go Test and 6 - Minute Walk Test. The collected data will be analyzed using appropriate statistical tools, including comparison models (ANOVA, Mann - Whitney U test) and correlation models (Pearson - Spearman). This research is expected to enhance theoretical knowledge regarding the relationship between nutrition, biochemical markers and rehabilitation outcomes in stroke patients with hypoalbuminemia. More specifically, it aims to explore the underlying mechanisms through which nutrition affects recovery - a field that remains unexplored. Additionally, the anticipated finding may contribute to the development of clinical guidelines and therapeutic approaches for the nutritional management of patients with low albumin levels, promoting personalized nutritional strategies that support effective post - stroke rehabilitation.",[249,250,65,251,252,253,27],"Stroke","Hypoalbuminemia","Osteopenia","Malnutrition (Calorie)","Protein-energy Malnutrition",[255,256,257,258,259,260,261,262,263,264],"protein supplementation","nutritional intervention","albumin levels","stroke","stroke rehabilitation","eating disorders","malnutrition","nutritional assessment","sarcopenia","osteopenia","2025-04-29",{"date":267,"type":40},"2025-05-08",{"date":269,"type":20},"2025-05-05",{"date":271,"type":20},"2030-05-05",{"name":273,"class":47},"University of Ioannina"]