[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"functional-inspiratory-muscle-training\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:functional-inspiratory-muscle-training":28},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,3,0,[8,48,77],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":4,"eligibilityCriteria":15,"healthyVolunteers":11,"sex":16,"minAge":17,"maxAge":18,"enrollmentInfo":19,"targetDuration":4,"studyType":22,"phases":23,"briefSummary":25,"conditions":26,"keywords":29,"overallStatus":35,"whyStopped":4,"lastUpdateSubmitDate":36,"lastUpdatePostDateStruct":37,"startDateStruct":40,"completionDateStruct":42,"leadSponsor":44,"locationsCount":47},"100607447","functional-inspiratory-training-in-bronchiectasis-100607447",false,"NCT07188675","Functional Inspiratory Training in Bronchiectasis","Effects of Functional Inspiratory Muscle Training on Pulmonary Function, Muscle Thickness, and Core Performance in Patients With Bronchiectasis","Inclusion Criteria:\n\n* Age between 18 and 30 years\n* Diagnosed with bronchiectasis\n* Clinically stable\n* Able to cooperate\n* Able to walk independently\n* Volunteering to participate in the study\n\nExclusion Criteria:\n\n* History of acute exacerbation and\u002For hospitalization within the past 4 weeks\n* Change in medical treatment within the past month\n* Known diagnosed conditions affecting balance (visual, auditory, vestibular, or musculoskeletal disorders)\n* Participation in a supervised physiotherapy rehabilitation program within the past 6 months\n* History of lung or liver transplantation","ALL","18 Years","30 Years",{"count":20,"type":21},38,"ESTIMATED","INTERVENTIONAL",[24],"NA","Bronchiectasis is a chronic respiratory disease clinically characterized by recurrent pulmonary exacerbations, chronic cough, and sputum production, and is associated with an increase in the airway-artery ratio and permanent airway dilatation. It is recognized as the third most common chronic respiratory disease after chronic obstructive pulmonary disease (COPD) and asthma. In the International Classification of Diseases and Related Health Problems (ICD-10), it has its own diagnostic code (J47.9).\n\nIn bronchiectasis, mucociliary clearance is impaired due to bronchial dilatation, and the insufficient clearance of bacteria and mucus from the respiratory tract leads to persistent infection, inflammation, and further airway damage. Progressive airway damage results in impaired lung function, worsening of symptoms, and, ultimately, respiratory failure and death. It can represent the final pathway of various infectious, allergic, inflammatory, genetic, and degenerative disorders, making it one of the most complex and heterogeneous syndromes. Some patients present with daily symptoms, while others remain asymptomatic except during exacerbations. The most common symptom is chronic cough caused by purulent or mucopurulent sputum. Other symptoms include dyspnea, pleuritic chest pain, wheezing, fatigue, and weight loss. Fever, however, is not a common finding and differs from pneumonia.\n\nThe most frequently used classification system categorizes bronchiectasis into varicose, cylindrical, and saccular (cystic) types. In the most severe form, the saccular type, the bronchi lose their structural integrity completely, forming cystic structures filled with secretions. The mildest form is cylindrical, in which the bronchi have thick, straight walls. In the varicose type, localized narrowings are observed. Diagnosis is made following history and physical examination, with high-resolution computed tomography (HRCT) being the most sensitive and specific method, along with sputum culture and chest radiography.\n\nThe goals of bronchiectasis treatment are to manage symptoms, prevent complications, and improve quality of life. Both pharmacological and patient-managed interventions are commonly applied. Pharmacological treatments include antibiotics, bronchodilators, and corticosteroids, which are generally administered via inhalation. Patient-managed interventions require active participation and behavioral modification. Within published guidelines, airway clearance techniques are widely described under pulmonary rehabilitation (PR), but there is no consensus regarding PR itself. For individuals with reduced exercise tolerance, participation in PR and engagement in physical activity are recommended. However, research has shown that referral rates to PR are often low, and exercise and physical activity are not consistently prescribed.\n\nWithin PR, techniques such as the active cycle of breathing techniques (ACBT), postural drainage, thoracic expansion exercises, and various airway clearance methods are applied, with inspiratory muscle training (IMT) forming an important component. Functional inspiratory muscle training (FIMT) is an IMT program developed by considering not only the ventilatory roles of the respiratory muscles but also their non-respiratory functions. FIMT integrates inspiratory muscle training with core stabilization and postural control exercises. The rhythmic co-contractions of the muscles in the core region support trunk stability and provide the basis for movement. In the first stage of the program, participants receive IMT, and subsequently, core stabilization training and dynamic trunk activation exercises are incorporated into the intervention.\n\nA review of the literature reveals that no studies have investigated the effectiveness of FIMT in adults with bronchiectasis. In our study, we aim to evaluate the effects of FIMT, applied in addition to home-based chest physiotherapy, on pulmonary function, diaphragm thickness, balance, core stability, functional capacity, physical activity, posture, and quality of life in adults with bronchiectasis. Furthermore, we aim to compare these outcomes with those of IMT applied alongside home-based chest physiotherapy. We believe that this approach will contribute to the development of treatment strategies in clinical practice and help address existing gaps in the literature.",[27,28],"Bronchiectasis","Functional Inspiratory Muscle Training",[30,31,32,33,34],"bronchiectasis","functional inspiratory muscle training","core stability","muscle thickness","respiratory function","RECRUITING","2026-02-06",{"date":38,"type":39},"2026-02-10","ACTUAL",{"date":41,"type":39},"2025-11-15",{"date":43,"type":21},"2026-06-30",{"name":45,"class":46},"Elif Kabasakal","OTHER",1,{"id":49,"slug":50,"hasResults":11,"nctId":51,"briefTitle":52,"officialTitle":53,"acronym":4,"eligibilityCriteria":54,"healthyVolunteers":11,"sex":16,"minAge":17,"maxAge":55,"enrollmentInfo":56,"targetDuration":4,"studyType":22,"phases":58,"briefSummary":59,"conditions":60,"keywords":63,"overallStatus":35,"whyStopped":4,"lastUpdateSubmitDate":68,"lastUpdatePostDateStruct":69,"startDateStruct":71,"completionDateStruct":73,"leadSponsor":75,"locationsCount":47},"100596936","effectiveness-of-functional-respiratory-muscle-training-in-post-covid-19-syndrome-100596936","NCT07051954","Effectiveness of Functional Respiratory Muscle Training in Post-COVID-19 Syndrome","Investigation of the Effects of Functional Respiratory Muscle Training on Respiratory Muscle Function, Exercise Capacity, Skeletal Muscle Strength, and Muscle Endurance in Individuals With Post-COVID-19 Syndrome","Inclusion Criteria:\n\n* Diagnosed with Post-COVID-19 Syndrome.\n* Literate and able to understand study procedures.\n* Aged between 18 and 65 years.\n* Willing to voluntarily participate in the study.\n* Classified as functional class 2-3 according to the Post-COVID-19 Functional Status Scale (PCFS).\n* Clinically stable; comorbid conditions such as hypertension or diabetes must be controlled.\n* No orthopedic or neurological conditions that would prevent assessment of peripheral muscle strength, balance, or exercise capacity.\n\nExclusion Criteria:\n\n* History of recent myocardial infarction or pulmonary embolism.\n* Presence of uncontrolled chronic diseases.\n* Any orthopedic or neurological disorders that limit mobility.\n* Neurological impairments (e.g., cerebrovascular disease) or psychiatric disorders that impair cooperation or compliance with exercise testing.","65 Years",{"count":57,"type":21},40,[24],"This study aims to investigate the effects of core stabilization exercises and functional inspiratory muscle training (IMT) on various physiological and psychological parameters in individuals with post-COVID-19 syndrome. Participants diagnosed with post-COVID-19 syndrome will be randomly assigned to two groups using stratified computer-assisted randomization. One group will undergo an 8-week core stabilization training, while the other will receive combined core stabilization and IMT training. Exercise training will be conducted three times a week, with each session lasting 50 minutes.\n\nComprehensive pre- and post-intervention assessments will be conducted, including exercise capacity, respiratory and peripheral muscle strength, trunk endurance, balance, anxiety, depression, and fatigue levels. The primary outcome measures are respiratory muscle strength and trunk endurance.\n\nParticipants must be aged 18-65 years, have at least a primary education level, speak Turkish, and be classified as level 2-3 on the Post-COVID-19 Functional Status Scale (PCFS). Eligible participants will be referred by the Internal Medicine Department at Hacettepe University.\n\nThe study will utilize various assessment tools, including maximal inspiratory\u002Fexpiratory pressure (MIP\u002FMEP) tests, Functional Movement Screen (FMS), plank and Sorenson endurance tests, the Timed Up and Go Test for balance, handgrip and knee extension strength tests, body composition analysis, and the SF-36 quality of life questionnaire.",[61,28,62],"Post COVID-19 Syndrome","Core Stabilization",[64,65,66,67,62],"Post-COVID Syndrome","Trunk Muscle Endurance","Exercise Capacity","Functional Inspiratory Muscle Training (IMT)","2026-01-13",{"date":70,"type":39},"2026-01-14",{"date":72,"type":39},"2025-09-15",{"date":74,"type":21},"2026-12-30",{"name":76,"class":46},"Hacettepe University",{"id":78,"slug":79,"hasResults":11,"nctId":80,"briefTitle":81,"officialTitle":82,"acronym":4,"eligibilityCriteria":83,"healthyVolunteers":11,"sex":16,"minAge":17,"maxAge":55,"enrollmentInfo":84,"targetDuration":4,"studyType":22,"phases":86,"briefSummary":87,"conditions":88,"keywords":92,"overallStatus":97,"whyStopped":4,"lastUpdateSubmitDate":98,"lastUpdatePostDateStruct":99,"startDateStruct":101,"completionDateStruct":102,"leadSponsor":104,"locationsCount":47},"100567790","effect-of-functional-inspiratory-muscle-training-in-patients-with-multiple-sclerosis-100567790","NCT06672770","Effect of Functional Inspiratory Muscle Training in Patients with Multiple Sclerosis","Investigation of the Effects of Functional Inspiratory Muscle Training on Respiratory Muscle Strength, Functional Exercise Capacity and Cognitive Function in Patients with Multiple Sclerosis","Inclusion Criteria:\n\n* Diagnosed with Relapsing Remitting Type Multiple Sclerosis (RRMS),\n* EDSS (Expanded Disability Status Scale in MS: EDSS) score ranging from 1-5,\n* Able to communicate (speak, understand, read and understand Turkish),\n* Individuals who have not had an attack in the last three months,\n* Individuals who have not received respiratory-based rehabilitation in the last six months will be included in the study.\n\nExclusion Criteria:\n\n* Those with neurological diseases other than MS,\n* Those who have functional exercise restrictions,\n* Those with chronic cardiac or pulmonary diseases such as chronic obstructive pulmonary disease (COPD), asthma, interstitial lung disease and heart failure that may affect respiratory muscle strength and respiratory functions,\n* Individuals who have had pneumonia due to viral or bacterial infection in the last six months or COVID-19 positive individuals proven by PCR-RT,\n* Those with orthopedic problems, persistent neck and back pain and\u002For radiculopathy that prevent them from participating in the study,\n* Those with diagnosed psychiatric disorders,\n* Those who use tobacco and tobacco products,\n* Participants with cooperation problems that may prevent evaluations and treatment will not be included in the study.",{"count":85,"type":21},63,[24],"This study aims to investigate the effects of functional inspiratory muscle training, basic inspiratory muscle training and physical activity in addition to respiratory exercises on respiratory muscle strength, respiratory function, cognition, walking, balance, functional exercise capacity, physical activity, quality of life and core muscles in volunteer Multiple Sclerosis (MS) patients. This study is planned as a prospective, randomized and experimental study.",[89,28,90,91],"Core Muscles","Multiple Sclerosis","Respiratory Muscles",[93,94,95,96],"Core muscles","Functional inspiratory muscle training","Multiple sclerosis","Respiratory muscles","NOT_YET_RECRUITING","2024-11-01",{"date":100,"type":39},"2024-11-04",{"date":98,"type":21},{"date":103,"type":21},"2025-12-20",{"name":105,"class":46},"Selcuk University"]