[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"functional-neurological-disorder\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:functional-neurological-disorder":25},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,10,0,[8,41,66,91,113,135,165,193,224,263],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":13,"acronym":4,"eligibilityCriteria":14,"healthyVolunteers":11,"sex":15,"minAge":16,"maxAge":17,"enrollmentInfo":18,"targetDuration":21,"studyType":22,"phases":4,"briefSummary":23,"conditions":24,"keywords":4,"overallStatus":28,"whyStopped":4,"lastUpdateSubmitDate":29,"lastUpdatePostDateStruct":30,"startDateStruct":33,"completionDateStruct":35,"leadSponsor":37,"locationsCount":40},"100543921","establishment-of-an-interdisciplinary-functional-neurological-disorder-fnd-treatment-program-and-development-of-a-clinical-care-pathway-for-fnd-100543921",false,"NCT06362161","Establishment of an Interdisciplinary Functional Neurological Disorder (FND) Treatment Program and Development of a Clinical Care Pathway for FND","Inclusion Criteria:\n\n* Diagnosis of FND\n* Can read and write English fluently\n* Referred to UAB outpatient treatment for FND in physical, occupational, or speech therapy\n* Referred to UAB outpatient treatment for FND in psychiatry\n* Referred to inpatient consult for FND at Children's of Alabama or UAB Hospital\n* Parent\u002Fguardian willing to participate in the study with a pediatric patient\n\nExclusion Criteria:\n\n* Unable to read or write English fluently","ALL","8 Years","89 Years",{"count":19,"type":20},1100,"ESTIMATED","4 Months","OBSERVATIONAL","The purpose of this study is to help providers develop an interdisciplinary treatment pathway for functional neurological disorder (FND) at University of Alabama at Birmingham (UAB), and will involve psychiatry, speech therapy, physical therapy, and occupational therapy. The study will also help providers to evaluate the treatment pathway and publish results regarding the process and outcomes.",[25,26,27],"Functional Neurological Disorder","Convulsion, Non-Epileptic","Functional Seizure","RECRUITING","2026-06-08",{"date":31,"type":32},"2026-06-11","ACTUAL",{"date":34,"type":32},"2025-07-18",{"date":36,"type":20},"2028-12-31",{"name":38,"class":39},"University of Alabama at Birmingham","OTHER",1,{"id":42,"slug":43,"hasResults":11,"nctId":44,"briefTitle":45,"officialTitle":46,"acronym":4,"eligibilityCriteria":47,"healthyVolunteers":48,"sex":15,"minAge":49,"maxAge":50,"enrollmentInfo":51,"targetDuration":4,"studyType":22,"phases":4,"briefSummary":53,"conditions":54,"keywords":55,"overallStatus":28,"whyStopped":4,"lastUpdateSubmitDate":57,"lastUpdatePostDateStruct":58,"startDateStruct":60,"completionDateStruct":62,"leadSponsor":64,"locationsCount":40},"100629745","feasibility-of-remotely-measured-activity-behavior-for-individuals-with-functional-neurologic-disorder-100629745","NCT07478666","Feasibility of Remotely Measured Activity Behavior for Individuals With Functional Neurologic Disorder","Feasibility and Construct Validity of Remotely Measured Activity Behavior for Individuals With Functional Neurologic Disorder","Inclusion Criteria:\n\nParticipants with FND:\n\n•Neurologist-confirmed diagnosis of functional neurologic disorder with motor symptoms, sensory symptoms, dizziness, and\u002For seizures\n\nHealthy Controls:\n\n* Roughly matched to participants with FND for age and sex\n* Free from major disease that affects mobility (e.g., neurologic, movement, cardiac, pulmonary, renal, and psychiatric disorders) by history.\n\nExclusion Criteria:\n\nParticipants with FND\n\n* Physical or cognitive symptoms impairing ability to engage with the protocol (e.g., seizure frequency \\> 10\u002Fday).\n* Diagnosis of other major neurologic, cardiovascular, musculoskeletal, or psychiatric disorder that affects mobility as determined by the principal investigator",true,"18 Years","65 Years",{"count":52,"type":20},40,"This study evaluates whether remotely measured daily activity behavior, captured through a thigh-worn accelerometer, can serve as a reliable and ecologically valid indicator of symptom impact in individuals with Functional Neurologic Disorder (FND). Current clinician-rated assessments capture only a single time point and do not reflect day-to-day symptom variability or functional impact. The study will (1) assess the feasibility of continuous activity monitoring in people with FND, (2) examine associations between activity behavior and established clinician- and patient-reported FND measures, and (3) qualitatively explore participants' lived experiences of daily activity. Findings aim to address a critical gap in understanding real-world function in this heterogeneous population.",[25],[56],"functional neurological disorder","2026-05-13",{"date":59,"type":32},"2026-05-18",{"date":61,"type":32},"2026-04-16",{"date":63,"type":20},"2027-06",{"name":65,"class":39},"University of Colorado, Denver",{"id":67,"slug":68,"hasResults":11,"nctId":69,"briefTitle":70,"officialTitle":71,"acronym":4,"eligibilityCriteria":72,"healthyVolunteers":11,"sex":15,"minAge":49,"maxAge":73,"enrollmentInfo":74,"targetDuration":4,"studyType":76,"phases":77,"briefSummary":79,"conditions":80,"keywords":4,"overallStatus":28,"whyStopped":4,"lastUpdateSubmitDate":82,"lastUpdatePostDateStruct":83,"startDateStruct":85,"completionDateStruct":87,"leadSponsor":89,"locationsCount":40},"100640262","the-effect-of-psychoeducational-diagnosis-communication-on-perception-of-illness-satisfaction-and-behavioral-intentions-among-patients-with-functional-neurological-movement-disorders-100640262","NCT07588282","The Effect of Psychoeducational Diagnosis Communication on Perception of Illness, Satisfaction, and Behavioral Intentions Among Patients With Functional Neurological Movement Disorders","The Effect of Psychoeducational Diagnosis Communication on Perception of Illness, Satisfaction, and Behavioral Intentions in Patients With Functional Neurological Movement Disorders: An Intervention Study Using a Within-Subject Design","Inclusion Criteria:\n\n* Presence of any of the following functional movement disorders:\n\n  * Functional paralysis\n  * Functional seizures\n  * Functional tremor\n  * Functional drop attacks\n  * Functional dystonia\n  * Functional twitching\n  * Functional facial symptoms\n  * Functional tics\n  * Functional parkinsonism\n\nExclusion Criteria:\n\n* The patient is unable to give informed consent.\n* The patient is temporarily unable to give informed consent.\n* The patient does not have sufficiently understand German language to answer the questionnaires (the questionnaires are available only in German).","80 Years",{"count":75,"type":20},35,"INTERVENTIONAL",[78],"NA","Functional neurological movement disorders are common conditions that can lead to significant limitations in daily life. They result from a functional disorder in the brain. A clear, understandable, and empathetic explanation of the diagnosis is a crucial first step in treatment. The purpose of this clinical study is to investigate how a clear and detailed explanation of the diagnosis of functional neurological movement disorders affects patients' understanding of their condition and their symptoms The investigators are interested in how well patients understand the diagnosis and the symptoms they experience as the disease progresses, as well as how the conversation between patient and doctor is experienced from both perspectives. In addition, as part of the study, a one-time examination using brain imaging (magnetic resonance imaging) will be conducted to better understand possible differences in brain function.",[25,81],"Functional Movement Disorder","2026-05-11",{"date":84,"type":32},"2026-05-14",{"date":86,"type":32},"2026-03-31",{"date":88,"type":20},"2027-12-31",{"name":90,"class":39},"Medical University of Graz",{"id":92,"slug":93,"hasResults":11,"nctId":94,"briefTitle":95,"officialTitle":96,"acronym":97,"eligibilityCriteria":98,"healthyVolunteers":11,"sex":15,"minAge":99,"maxAge":4,"enrollmentInfo":100,"targetDuration":4,"studyType":22,"phases":4,"briefSummary":102,"conditions":103,"keywords":4,"overallStatus":28,"whyStopped":4,"lastUpdateSubmitDate":104,"lastUpdatePostDateStruct":105,"startDateStruct":107,"completionDateStruct":109,"leadSponsor":111,"locationsCount":40},"100634340","investigation-of-patients-presenting-with-acute-functional-neurological-symptoms-100634340","NCT07538414","Investigation of Patients Presenting With Acute Functional Neurological Symptoms","Functional Neurological Disorders in Acute Hospital Care","FONDA","Inclusion Criteria:\n\n* Patients older than 16 years old presenting as an emergency case to the University Hospital Basel between 1 January 2012 and 31 March 2026\n* with acute neurological symptoms requiring immediate neurological work-up (e.g, acute motor or sensory disturbance, acute speech disorder, acute vestibular disorder, acute cognitive disorder, acute consciousness disorder, acute seizure disorder)\n* and a documented diagnostic evaluation during hospitalization.\n\nExclusion Criteria:\n\n* Documented refusal for further use of health related data for research purposes\n* Insufficient documentation to determine diagnosis or clinical course\n* Incomplete or inconsistent datasets compromising valid endpoint determination\n* Younger than 16 years","16 Years",{"count":101,"type":20},1000,"Retrospective Single-center Analysis of Patients Presenting With Acute Neurological Symptoms, Aiming to Characterize the Frequency, Clinical Features, Diagnostic Pathways, and Healthcare Utilization of Patients with Functional Neurological Diseases",[25],"2026-04-15",{"date":106,"type":32},"2026-04-20",{"date":108,"type":32},"2026-03-30",{"date":110,"type":20},"2050-12",{"name":112,"class":39},"University Hospital, Basel, Switzerland",{"id":114,"slug":115,"hasResults":11,"nctId":116,"briefTitle":117,"officialTitle":117,"acronym":118,"eligibilityCriteria":119,"healthyVolunteers":11,"sex":15,"minAge":49,"maxAge":4,"enrollmentInfo":120,"targetDuration":4,"studyType":22,"phases":4,"briefSummary":122,"conditions":123,"keywords":125,"overallStatus":28,"whyStopped":4,"lastUpdateSubmitDate":104,"lastUpdatePostDateStruct":128,"startDateStruct":129,"completionDateStruct":131,"leadSponsor":133,"locationsCount":40},"100633493","impact-of-theta-burst-repetitive-transcranial-magnetic-stimulation-on-the-patients-self-reported-improvement-in-their-motor-functional-neurological-disorder-100633493","NCT07527403","Impact of Theta Burst Repetitive Transcranial Magnetic Stimulation on the Patient's Self-reported Improvement in Their Motor Functional Neurological Disorder","Thêta-mTNF","Inclusion Criteria:\n\n* Patients over 18\n* Patients with FND, either deficits or abnormal movements, diagnosed by a neurologist.\n* Patients with an indication for validated neuronavigated rTMS treatment.\n* Patients who have indicated that they do not object to participating in the study.\n\nExclusion Criteria:\n\n* Patients subject to legal protection (legal guardianship, conservatorship, trusteeship)\n* Patients deprived of liberty",{"count":121,"type":20},22,"Functional neurological disorder (FND) is a condition that causes significant suffering and disability. It is defined by the presence of neurological symptoms that interfere with an individual's functioning and are not consistent with any known anatomical lesion but that causes significant functional impairment. The investigators are particularly interested in motor symptoms (abnormal movements or motor deficits).\n\nRepetitive transcranial magnetic stimulation (rTMS) is a non-invasive and acceptable treatment that has proven effective in certain chronic pain conditions, depression, and OCD. The investigators would like to evaluate the impact of rTMS on the patient's overall perception of change, particularly on the clinical symptoms of motor FND. Secondary objectives include evaluating the overall effect on symptoms from the clinician's perspective, the effect on quality of life, on depressive and anxiety symptoms and associated dissociation, as well as evaluating any changes in the sense of agency and identifying the side effects of rTMS treatment.",[25,124],"Motor FND",[25,124,126,127],"Repetitive Transcranial Magnectic Stimulation (rTMS)","Theta burst rTMS",{"date":106,"type":32},{"date":130,"type":32},"2026-03-13",{"date":132,"type":20},"2028-03",{"name":134,"class":39},"Hospital Center Guillaume Régnier",{"id":136,"slug":137,"hasResults":11,"nctId":138,"briefTitle":139,"officialTitle":140,"acronym":141,"eligibilityCriteria":142,"healthyVolunteers":11,"sex":15,"minAge":49,"maxAge":4,"enrollmentInfo":143,"targetDuration":4,"studyType":76,"phases":145,"briefSummary":146,"conditions":147,"keywords":151,"overallStatus":155,"whyStopped":4,"lastUpdateSubmitDate":156,"lastUpdatePostDateStruct":157,"startDateStruct":159,"completionDateStruct":161,"leadSponsor":163,"locationsCount":4},"100598908","the-feasibility-and-acceptability-of-an-online-yoga-program-for-people-with-functional-neurological-disorders-100598908","NCT07077603","The Feasibility and Acceptability of an Online Yoga Program for People With Functional Neurological Disorders","Acceptability and Feasibility of an Online Yoga Programme for Adults With a Functional Neurological Disorder.","YOGA-FUND","Inclusion Criteria:\n\n* Participants able to give informed consent.\n* Aged 18 years and over.\n* Participants with a confirmed clinical diagnosis of functional neurological disorder with dissociative seizures.\n* Access to WiFi and an electronic device on which to view and participate in the yoga programme.\n\nExclusion Criteria:\n\n* Participants with severe fatigue that would prevent engagement for the duration of the intervention (assessed by clinical neurology team member).\n* Participants who regularly practice yoga i.e., participants who practice each week.\n* People with a confirmed concurrent diagnosis of epilepsy.",{"count":144,"type":20},30,[78],"This is a feasibility study to see if it is acceptable and helpful for people living with a functional neurological disorder to receive online group yoga sessions to improve their wellbeing",[25,148,149,150],"Dissociative Seizures","Psychogenic Seizure","Non-Epileptic Seizure",[152,56,153,154],"dissociative seizure","psychogenic seizure","yoga","NOT_YET_RECRUITING","2025-07-11",{"date":158,"type":32},"2025-07-22",{"date":160,"type":20},"2025-08",{"date":162,"type":20},"2026-06",{"name":164,"class":39},"Nottingham University Hospitals NHS Trust",{"id":166,"slug":167,"hasResults":11,"nctId":168,"briefTitle":169,"officialTitle":169,"acronym":170,"eligibilityCriteria":171,"healthyVolunteers":11,"sex":15,"minAge":49,"maxAge":172,"enrollmentInfo":173,"targetDuration":4,"studyType":76,"phases":175,"briefSummary":176,"conditions":177,"keywords":181,"overallStatus":155,"whyStopped":4,"lastUpdateSubmitDate":184,"lastUpdatePostDateStruct":185,"startDateStruct":187,"completionDateStruct":189,"leadSponsor":191,"locationsCount":4},"100593436","brain-computer-interface-rehabilitation-and-virtual-environments-in-functional-neurological-disorder-brave-fnd-100593436","NCT07006415","Brain-computer Interface Rehabilitation And Virtual Environments in Functional Neurological Disorder (BRAVE-FND)","BRAVE-FND","Inclusion Criteria:\n\n* DSM5 diagnosis of motor FND (limb weakness, gait disorder, tremor or dystonia) from a neurologist and\u002For neuropsychiatrist.\n* Moderate or severe symptoms (≥4 on Clinical Global Impression Severity (CGI-S) scale).\n* Able to tolerate VR and BCI use.\n* Age 18 - 60 years.\n* English speaking.\n\nExclusion Criteria:\n\n* Current diagnosis of epilepsy, severe depression, bipolar disorder, psychotic disorder, personality disorder, or drug\u002Falcohol dependence\u002Fharmful use (defined as meeting DSM-5 criteria) (Mini International Neuropsychiatric Interview \\[MINI\\] 7.0). Positive diagnoses on the MINI will be subject to confirmation at clinical interview by a psychiatrist.\n* Current diagnosis of epilepsy, autistic spectrum disorder, dementia, learning disability (defined as meeting DSM-5 criteria) based on clinical interview by a psychiatrist.\n* A pacemaker, implantable cardioverter-defibrillator or any other implanted electronic or metallic device.\n* Current pregnancy.\n* Non-registration with a GP or failure to consent to sharing of the GP summary care record and any psychiatric assessments held.\n* Those enrolled in another clinical or research study.\n* Those unable to give informed consent.","60 Years",{"count":174,"type":20},24,[78],"The purpose of this study is to determine whether a course of rehabilitation using a device called a brain-computer interface can change the level of control people feel over bodily movements, in functional neurological disorder.",[25,178,179,180],"Conversion Disorder","Functional Neurological Disorders","Conversion Disorder With Weakness\u002FParalysis",[182,183],"brain-computer interface","rehabilitation","2025-05-27",{"date":186,"type":32},"2025-06-05",{"date":188,"type":20},"2025-10-01",{"date":190,"type":20},"2028-01-31",{"name":192,"class":39},"King's College London",{"id":194,"slug":195,"hasResults":11,"nctId":196,"briefTitle":197,"officialTitle":198,"acronym":199,"eligibilityCriteria":200,"healthyVolunteers":11,"sex":15,"minAge":49,"maxAge":201,"enrollmentInfo":202,"targetDuration":4,"studyType":76,"phases":203,"briefSummary":204,"conditions":205,"keywords":206,"overallStatus":28,"whyStopped":4,"lastUpdateSubmitDate":215,"lastUpdatePostDateStruct":216,"startDateStruct":218,"completionDateStruct":220,"leadSponsor":222,"locationsCount":40},"100583236","pilot-neurobehavioral-therapy-for-functional-neurological-disorder-100583236","NCT06873698","Pilot Neurobehavioral Therapy for Functional Neurological Disorder","A Pilot Randomized Controlled Trial (RCT) of Neurobehavioral Therapy (NBT) Vs Standard Medical Care (SMC) for Functional Neurological Disorder (FND)","NBT for mFND","Inclusion Criteria:\n\n* Individuals diagnosed with Motor Functional Neurological Disorder (mFND)\n* Individuals aged 18-70 years\n* At least 1 mFND symptom during the year prior to enrollment\n\nExclusion Criteria:\n\n* Current or past year self-injurious behavior\n* Current suicidality (PHQ-9 question 9 rated as 1 or above)\n* Current or past year psychosis\n* Pending litigation or current application for long term disability\n* Active substance or alcohol use disorders (dependence), at the discretion of the investigator if they preclude participation in the study\n* Serious illness requiring systemic treatment or hospitalization; the participant either completes therapy or is clinically stable on therapy, for at least 30 days prior to study entry\n* Inability to fill out the self-report surveys\n* Inability or unwillingness to participate in NBT and assigned homework\n* Currently enrolled in NBT aimed at mFND","70 Years",{"count":52,"type":20},[78],"The goal of this pilot randomized clinical trial is to learn if Neurobehavioral Therapy (NBT) works to treat motor functional neurological disorder (mFND) (also referred to as functional motor disorder).\n\nThe main questions it aims to answer are:\n\n* Does NBT lower mFND symptoms?\n* Does NBT lower common co-occurring symptoms and improve functioning?\n\nResearchers will compare NBT to standard medical care (SMC).\n\nParticipants will be randomized to receive either:\n\n* 12 weekly sessions of NBT, along with their SMC,\n* or continue receiving their SMC as provided by their treating clinicians.\n* all participants. regardless of group assignment, will complete a total of five in-clinic visits at the following time points: Baseline, 6 weeks, 12 weeks, 8 Months and 12 Months for self-report surveys to assess functional status, quality of life and mFND symptoms.",[25],[207,178,208,209,210,211,212,213,214],"mFND","Functional Neurologic Disorder","Neurobehavioral Therapy","FND","Psychogenic Movement Disorder","Psychotherapy","motor functional neurological disorder","functional motor disorder","2025-03-26",{"date":217,"type":32},"2025-04-01",{"date":219,"type":32},"2024-09-25",{"date":221,"type":20},"2028-06",{"name":223,"class":39},"Rhode Island Hospital",{"id":225,"slug":226,"hasResults":11,"nctId":227,"briefTitle":228,"officialTitle":229,"acronym":4,"eligibilityCriteria":230,"healthyVolunteers":48,"sex":15,"minAge":4,"maxAge":4,"enrollmentInfo":231,"targetDuration":233,"studyType":22,"phases":4,"briefSummary":234,"conditions":235,"keywords":244,"overallStatus":155,"whyStopped":4,"lastUpdateSubmitDate":254,"lastUpdatePostDateStruct":255,"startDateStruct":257,"completionDateStruct":259,"leadSponsor":261,"locationsCount":4},"100571890","the-nrc-dataset-developing-a-minimum-dataset-for-multidisciplinary-rehabilitation-a-modified-e-delphi-study-100571890","NCT06726135","The NRC Dataset. Developing a Minimum Dataset for Multidisciplinary Rehabilitation: a Modified E-Delphi Study","The National Rehabilitation Centre Dataset. Development of a Minimum Dataset for Multidisciplinary Rehabilitation: a Modified E-Delphi Study","Inclusion Criteria:\n\nThe panel will aim to include clinicians with a minimum of 5 years' experience from a variety of professional backgrounds within the following specialist areas:\n\n* Neuro Rehab\n* Trauma Rehab\n* Community Rehab\n* Outpatient Rehabilitation services\n* Defence medical services\n* Psychology services\n* Amputee Rehab\n* Speech and Language therapy\n* Emergency department\n* Critical Care\n* Trauma and Orthopaedics\n* Rehabilitation Medicine\n\nIt is expected that the expert panel will include:\n\n* Medical Doctors\n* Dietitians\n* Physiotherapists\n* Psychologists\n* Prosthetists\n* Occupational therapists\n* Speech and Language therapists\n* Data-base managers\n* Researchers\u002FAcademics\n* Commissioners\n* Local service managers\n* A department of work and pensions representative\n* An epidemiologist\u002Fdata-scientist with healthcare financial modelling experience\n\nExclusion Criteria:\n\nIndividuals will be excluded from the expert panel for any of the following reasons:\n\n1. They do not have 5 years' experience in their specialist field\n2. They do not have an understanding of various health indicators and the appropriate outcome measure instruments required to evaluate these health indicators.\n3. They have no understanding of how demographic and socio-economic variables impact health outcomes\n4. They have no understanding of how to evaluate clinical effectiveness and cost efficiency of inpatient rehabilitation services.\n5. Their professional background is not represented in the above noted specialist areas",{"count":232,"type":20},50,"6 Months","Several rehabilitation datasets are presently in use for specific patient groups in England. The 'National Clinical Audit of Specialist Rehabilitation for patients with complex needs following major injury' (NCASRI) evaluated outcomes within a cohort of Major Trauma patients between 2015 and 2018 using data from two of these datasets. The NCASRI project outlined some of the shortcomings of the pre-existing datasets and highlighted the need for a single National Rehabilitation Dataset to provide long term evaluation of a variety of patient presentations.\n\nThe proposed study will seek to develop such a dataset by means of an E-delphi study. This study will seek consensus from a panel of experts on the data items required to measure the effectiveness and socio-economic impact of multidisciplinary inpatient rehabilitation. Providing commissioners, researchers and clinicians with the data required to improve patient care, conduct research and develop rehabilitation services.\n\nThere are three potential phases to this study:\n\n* Phase one involves the establishment of a core domain set, outlining what information (data) should be included in the NRC core dataset.\n* Phase one will consist of at least 2 rounds of voting, with successive rounds of voting undertaken until an a-priori consensus of 70% is reached for all core data items marked as mandatory\u002Fcritical data in fitting OMERACT guidelines.\n* After 2 rounds, any data item that have reached consensus will be included in the final dataset. These core domain (data items) will then be excluded from subsequent rounds of voting.\n* A maximum of 4 rounds will be allowed in Phase 1. At which point the highest-ranking data items remaining with a consensus above 60% from each of the pre-identified categories will be included in the final dataset.\n* Phase two will explore what tools should be used to collect the core domains (outcome measure instruments) for each category outlined in phase 1.\n* Phase 2 will follow the same protocol for including outcome measure instruments into the core outcome set as were required to include core data items from phase 1.\n* If a consensus of equal or greater than 60% cannot be reached using an E-Delphi method in either phase 1 or phase 2 then a virtual meeting will be held amongst all expert panel members to reach consensus using a nominal group technique (phase 3).",[236,237,238,239,240,241,25,242,243],"Pain","Traumatic Brain Injury","Major Trauma","Multiple Sclerosis","Amputees \u002F Rehabilitation","Spinal Cord Injuries (SCI)","Intensive Care Unit (ICU) Acquired Weakness (ICU - AW)","Trauma Related Injuries",[245,246,247,248,249,250,251,252,253],"E-delphi","Delphi","Multidisciplinary","Rehabilitation","Core outcome set","Dataset","national rehabilitation centre","outcome measure instruments","inpatient","2024-12-15",{"date":256,"type":32},"2024-12-19",{"date":258,"type":20},"2025-01",{"date":260,"type":20},"2025-06",{"name":262,"class":39},"ThomasCorbett",{"id":264,"slug":265,"hasResults":11,"nctId":266,"briefTitle":267,"officialTitle":268,"acronym":269,"eligibilityCriteria":270,"healthyVolunteers":11,"sex":15,"minAge":49,"maxAge":201,"enrollmentInfo":271,"targetDuration":4,"studyType":76,"phases":273,"briefSummary":274,"conditions":275,"keywords":276,"overallStatus":28,"whyStopped":4,"lastUpdateSubmitDate":282,"lastUpdatePostDateStruct":283,"startDateStruct":285,"completionDateStruct":287,"leadSponsor":289,"locationsCount":40},"100548578","clinical-evaluation-of-hrv-biofeedback-in-functional-neurological-disorders-compared-to-placebo-100548578","NCT06422819","Clinical Evaluation of HRV Biofeedback in Functional Neurological Disorders Compared to Placebo","Probing the Heart Rate Variability Biofeedback as an Innovative and Non-invasive Treatment for Functional Neurological Disorders Guided by a Multimodal Approach of Autonomic Nervous System.","HRV_BFB_FND","Inclusion Criteria:\n\n* Functional Neurological Disorders (FND) diagnosis must be medically established\n* Participants must have a smartphone (android ou Iphone)\n* Participants must be of the age of majority\n* Participants must have signed an informed consent\n* Sufficiently fluent in French to understand study documents and instructions\n* Consistency in performing repeated questionnaires\n* Normal or corrected-to-normal visual acuity\n\nExclusion Criteria:\n\n* Specially protected participants: juveniles, pregnant womens, nursing mothers, law's protection peoples\n* Participants suffering from a severe psychiatric disease needing specialised attention\n* History of severe neurosurgical pathology\n* Alcohol dependence or drug use\n* Participants suffering from or have suffered from a severe disease causing autonomic dysfunctions (heart failure, asthma, blood disease, renal failure, peripheral neuropathy, vagotomy, thyroid disorder, alcoholism, liver disease, amyloidosis)\n* Participants taking medication which could be impact autonomic nervous system activity (anticholinergic, antiarrhythmics, clonidine, beta-blockers, tricyclic anti-depressants, metronidazole)\n* Participants placing under judicial or administrative supervisions",{"count":272,"type":20},31,[78],"Evaluation of the clinical effects of the Heart Rate Variability biofeedback training with patients suffering from Functional neurological Disorders compared with placebo.",[25],[25,277,278,279,280,281],"Emotional dysregulation","Autonomic nervous system","Endophenotypes","Biofeedback of Heart Rate Variability","Transdiagnostic approach","2024-09-10",{"date":284,"type":32},"2024-09-19",{"date":286,"type":32},"2024-09-09",{"date":288,"type":20},"2027-05",{"name":290,"class":39},"Centre hospitalier de l'Université de Montréal (CHUM)"]