[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"functional-status\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:functional-status":35},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,9,0,[8,60,88,111,139,168,203,243,274],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":15,"eligibilityCriteria":16,"healthyVolunteers":11,"sex":17,"minAge":18,"maxAge":4,"enrollmentInfo":19,"targetDuration":4,"studyType":22,"phases":23,"briefSummary":25,"conditions":26,"keywords":37,"overallStatus":47,"whyStopped":4,"lastUpdateSubmitDate":48,"lastUpdatePostDateStruct":49,"startDateStruct":52,"completionDateStruct":54,"leadSponsor":56,"locationsCount":59},"100603978","early-exercise-based-rehabilitation-in-patients-hospitalized-for-acute-pulmonary-embolism-100603978",false,"NCT07143539","Early Exercise-Based Rehabilitation in Patients Hospitalized for Acute Pulmonary Embolism","Early Exercise-based Rehabilitation in High-risk Patients Hospitalized for Acute Pulmonary Embolism: a Pragmatic Multicenter Randomized Partially Blinded Superiority Trial","RehabPE","Inclusion Criteria:\n\n1. Age ≥18 years\n2. Hospitalization for objectively confirmed acute symptomatic PE, defined as intraluminal filling defect of a segmental or more proximal pulmonary artery on computed tomography pulmonary angiography (CTPA) or a high-probability ventilation-perfusion scintigraphy, and admission within the past 7 days\n3. Increased risk for post-PE syndrome, defined as simplified Pulmonary Embolism Severity Index (sPESI) ≥1 point at the time of admission\n4. Written informed consent\n\nExclusion Criteria:\n\n1. Contraindication to EBR (known unstable cardiac conditions like angina pectoris, severe valvular heart disease, or severe resting pulmonary hypertension)\n2. Medical condition that clearly precludes participation in EBR (e.g., inability to walk, unstable joints, severe neurological impairment)\n3. Recently completed (i.e., \\\u003C6 months), ongoing, or planned in- or outpatient EBR, or planned supervised outpatient physiotherapy for any indication\n4. Planned hospitalization during follow-up (e.g., elective surgery or inpatient chemotherapy)\n5. Contraindication to anticoagulation\n6. Life expectancy \\\u003C1 year based on the treating physician's clinical judgement\n7. Known pregnancy\n8. Inability to speak German or French\n9. Participation in another study that prohibits concurrent participation in RehabPE\n10. Unable to provide informed consent (e.g., due to dementia)\n11. Unwilling to provide informed consent\n12. Prior enrollment in this study","ALL","18 Years",{"count":20,"type":21},160,"ESTIMATED","INTERVENTIONAL",[24],"NA","Up to half of patients with pulmonary embolism (PE) suffer from impaired quality of life, reduced physical capacity, and symptoms like shortness of breath even three months after diagnosis, despite standard treatment with anticoagulation (blood thinners). The randomized RehabPE trial investigates whether an early, structured rehabilitation program with physical training and patient education can prevent such long-term effects.\n\nThe study includes hospitalized patients with acute symptomatic PE who are at increased risk of impaired quality of life three months after diagnosis. After informed consent, patients are randomly assigned to one of two groups: one receives an early 6-8-week, center-based rehabilitation program; the other receives standard follow-up care without rehabilitation. The intervention group completes 16-18 outpatient sessions of endurance and strength training, along with two education sessions covering the condition, treatment, and symptom management.\n\nOver 180 days, changes in quality of life, physical exercise capacity, breathlessness, and psychological symptoms, and the time to return to work \u002F usual daily activities will be monitored and compared between groups.",[27,28,29,30,31,32,33,34,35,36],"Venous Thromboembolism (VTE)","Exercise Therapy","Quality of Life (QOL)","Anxiety Depression","Humans","Exercise Tolerance","Rehabilitation Exercise","Dyspnea","Functional Status","Pulmonary Embolism (Diagnosis)",[38,39,40,41,42,43,44,45,46],"pulmonary embolism","deep vein thrombosis","excercise-based rehabilitation","post-PE syndrome","health-related quality of life","anxiety","depression","dyspnea","impact of early excercise-based rehabilitation","RECRUITING","2026-06-11",{"date":50,"type":51},"2026-06-12","ACTUAL",{"date":53,"type":51},"2025-12-17",{"date":55,"type":21},"2028-06",{"name":57,"class":58},"Insel Gruppe AG, University Hospital Bern","OTHER",6,{"id":61,"slug":62,"hasResults":11,"nctId":63,"briefTitle":64,"officialTitle":65,"acronym":4,"eligibilityCriteria":66,"healthyVolunteers":11,"sex":17,"minAge":18,"maxAge":67,"enrollmentInfo":68,"targetDuration":70,"studyType":71,"phases":4,"briefSummary":72,"conditions":73,"keywords":77,"overallStatus":47,"whyStopped":4,"lastUpdateSubmitDate":78,"lastUpdatePostDateStruct":79,"startDateStruct":81,"completionDateStruct":83,"leadSponsor":85,"locationsCount":87},"100633639","functional-and-respiratory-predictors-of-early-postoperative-outcomes-100633639","NCT07529301","Functional and Respiratory Predictors of Early Postoperative Outcomes","The Effect of Functional Status and Respiratory Parameters on Early Postoperative Clinical Outcomes in Patients With Colorectal Cancer","Inclusion Criteria\n\nBeing between 18 and 80 years of age\n\nVoluntary agreement to participate in the study\n\nExclusion Criteria\n\nWithdrawal from the study at the participant's own request\n\nElimination Criteria\n\nPresence of a musculoskeletal condition that may prevent completion of the planned assessments\n\nPresence of a mental impairment\n\nHistory of psychiatric disorder\n\nHistory of previous major surgery","80 Years",{"count":69,"type":21},42,"12 Months","OBSERVATIONAL","Functional status is a fundamental indicator reflecting a patient's ability to perform activities of daily living and is closely associated with early postoperative outcomes. Patients with low functional capacity are known to have an increased risk of postoperative complications, prolonged length of hospital stay, and higher mortality rates. Similarly, respiratory function plays a decisive role in the development of postoperative complications and influences early surgical outcomes. In the preoperative period, inadequate respiratory capacity and poor functional performance increase the risk of postoperative pulmonary complications and delayed recovery. Therefore, functional and respiratory assessments are regarded as integral components of the preoperative preparation process.\n\nEarly outcomes in patients undergoing colorectal cancer surgery are of critical importance in reducing mortality and morbidity. In this surgical population, advanced age, comorbidities, and diminished physical capacity may further increase the risk of postoperative complications. Accordingly, the evaluation of preoperative functional status and physiological reserve has gained increasing importance for risk stratification and perioperative management. However, studies examining the impact of functional status and respiratory parameters on early surgical outcomes in patients with colorectal cancer remain limited. Consequently, the available evidence is insufficient to establish a standardized assessment approach in clinical practice.\n\nMoreover, objective evaluation of patients' functional and respiratory capacities in the preoperative period is essential for predicting surgical risk and planning individualized perioperative care. Determining the relationships between these parameters and early clinical outcomes may facilitate the identification of high-risk patients and contribute to the development of targeted strategies aimed at preventing postoperative complications. Findings obtained in this context are expected to provide a scientific basis for clinical decision-making and multidisciplinary patient management in individuals undergoing colorectal cancer surgery, thereby guiding clinical practice.",[74,35,75,76],"Colorectal Cancer","Respiratory Parameters","Clinical Outcomes",[74,35,75,76],"2026-04-09",{"date":80,"type":51},"2026-04-14",{"date":82,"type":51},"2026-03-01",{"date":84,"type":21},"2027-02-25",{"name":86,"class":58},"Müşerref Ebru YALÇIN",1,{"id":89,"slug":90,"hasResults":11,"nctId":91,"briefTitle":92,"officialTitle":93,"acronym":4,"eligibilityCriteria":94,"healthyVolunteers":11,"sex":17,"minAge":18,"maxAge":67,"enrollmentInfo":95,"targetDuration":97,"studyType":71,"phases":4,"briefSummary":98,"conditions":99,"keywords":4,"overallStatus":47,"whyStopped":4,"lastUpdateSubmitDate":102,"lastUpdatePostDateStruct":103,"startDateStruct":105,"completionDateStruct":107,"leadSponsor":109,"locationsCount":87},"100633225","functional-and-respiratory-determinants-of-long-term-colorectal-cancer-outcomes-100633225","NCT07523919","Functional and Respiratory Determinants of Long-Term Colorectal Cancer Outcomes","The Impact of Functional Status and Respiratory Parameters on Long-Term Outcomes in Colorectal Cancer","Inclusion Criteria:\n\n* Age between 18 and 80 years\n* Voluntary participation in the study\n\nExclusion Criteria:\n\n* Presence of musculoskeletal disorders that may prevent completion of the required tests\n* Presence of cognitive impairment\n* History of psychiatric disease\n* History of major surgery",{"count":96,"type":21},52,"2 Years","Colorectal cancer is one of the most commonly diagnosed malignancies worldwide and a leading cause of cancer-related morbidity and mortality. Its global incidence continues to increase, with a substantial proportion of cases diagnosed at advanced stages, which adversely affects prognosis. Patients diagnosed at an early stage and treated with surgery have significantly better long-term survival outcomes. Five-year survival rates are approximately 90% for stage I disease, decreasing to around 70% in stage II and 60% in stage III, and dropping to as low as 8% in stage IV disease.\n\nAdvanced age, family history, and environmental exposures are well-established risk factors for colorectal cancer. In addition, modifiable lifestyle factors-including smoking, physical inactivity, unhealthy dietary patterns, and obesity-have been shown to significantly increase the risk of disease.\n\nAlthough surgical resection remains the cornerstone of curative treatment in colorectal cancer, long-term outcomes are influenced not only by tumor stage but also by various patient-related factors, including comorbidities, functional capacity, and respiratory reserve. Functional status, which reflects a patient's ability to perform activities of daily living, is a key determinant of postoperative recovery and long-term outcomes. Reduced functional capacity has been associated with poorer long-term survival, diminished quality of life, and increased late morbidity. Therefore, objective preoperative assessment of functional status is considered essential for predicting long-term prognosis.\n\nRespiratory function also plays a critical role, particularly in patients undergoing abdominal surgery. Impaired pulmonary capacity increases the risk of postoperative pulmonary complications, prolongs hospital stay, and may indirectly affect long-term survival. However, studies evaluating the impact of preoperative respiratory parameters on long-term outcomes in patients with colorectal cancer remain limited. Furthermore, comprehensive analyses integrating both functional capacity and respiratory function are scarce in the current literature. Therefore, further investigation in this area is warranted.\n\nThe aim of this study is to evaluate the impact of functional status and respiratory parameters on long-term clinical outcomes in patients with colorectal cancer.\n\nH0: There is no statistically significant association between functional status, respiratory parameters, and long-term clinical outcomes in patients with colorectal cancer.\n\nH1: There is a statistically significant association between functional status, respiratory parameters, and long-term clinical outcomes in patients with colorectal cancer.",[74,100,35,101],"Respiratory Function","Long Term","2026-04-05",{"date":104,"type":51},"2026-04-13",{"date":106,"type":51},"2026-03-10",{"date":108,"type":21},"2028-03-10",{"name":110,"class":58},"Inonu University",{"id":112,"slug":113,"hasResults":11,"nctId":114,"briefTitle":115,"officialTitle":115,"acronym":4,"eligibilityCriteria":116,"healthyVolunteers":11,"sex":17,"minAge":18,"maxAge":117,"enrollmentInfo":118,"targetDuration":4,"studyType":71,"phases":4,"briefSummary":120,"conditions":121,"keywords":125,"overallStatus":47,"whyStopped":4,"lastUpdateSubmitDate":131,"lastUpdatePostDateStruct":132,"startDateStruct":134,"completionDateStruct":135,"leadSponsor":137,"locationsCount":87},"100628935","evaluation-of-the-relationship-between-the-conut-score-and-balance-and-functional-status-in-patients-with-chronic-stroke-100628935","NCT07468110","Evaluation Of The Relationship Between The Conut Score And Balance And Functional Status In Patients With Chronic Stroke","Inclusion Criteria:\n\n* Being 18 years of age or older\n* Having a diagnosis of ischemic or hemorrhagic stroke\n* At least 6 months having elapsed since the stroke event (chronic phase)\n* Being clinically stable\n* Being able to participate in standing and balance assessments (walking with an assistive device is acceptable)\n* Having sufficient cognitive capacity to understand and respond to the assessment scales used in the study\n* Voluntarily agreeing to participate in the study and providing written informed consent\n\nExclusion Criteria:\n\n* Acute or subacute stroke phase (\\\u003C 6 months)\n* Inability to administer assessment scales due to severe cognitive impairment or aphasia\n* Presence of other neurological disorders that may significantly affect balance and functional status (e.g., Parkinson's disease, multiple sclerosis, peripheral neuropathy)\n* Significant orthopedic conditions unrelated to stroke (e.g., advanced hip or knee osteoarthritis, lower extremity amputation)\n* Presence of active infection, malignancy, or systemic inflammatory disease (as these conditions may affect the CONUT score)\n* Cerebellar localization of the cerebrovascular event\n* History of major surgery or intensive care unit admission within the past 3 months\n* Inability to safely perform balance tests due to severe visual or hearing impairment\n* Patients with incomplete laboratory data or insufficient information to calculate the CONUT score","85 Years",{"count":119,"type":21},47,"The primary aim of this study is to evaluate the relationship between the CONUT score, which reflects nutritional status, and balance performance in patients with chronic stroke. The secondary aims are to investigate the association between the CONUT score and functional status and stroke-specific quality of life, as well as to assess the relationships of mid-upper arm circumference, an anthropometric indicator of nutritional status, and ultrasonographic rectus femoris muscle thickness, which reflects muscle mass, with balance performance, functional status, and stroke-specific quality of life. In addition, the study aims to examine the relationships between bone mineral density and balance, functional status, and ambulation level in patients with chronic stroke.",[122,123,124,35],"Chronic Stroke","CONUT Score","Balance Assessment",[123,126,127,128,129,130],"Tinetti Performance-Oriented Mobility Assessment (POMA)","Stroke-Specific Quality of Life Scale (SS-QOL)","Rectus femoris muscle thickness","Mid-upper arm circumference measurement","Bone Mineral Density (BMD)","2026-03-19",{"date":133,"type":51},"2026-03-24",{"date":106,"type":51},{"date":136,"type":21},"2027-03-10",{"name":138,"class":58},"Marmara University",{"id":140,"slug":141,"hasResults":11,"nctId":142,"briefTitle":143,"officialTitle":144,"acronym":4,"eligibilityCriteria":145,"healthyVolunteers":11,"sex":17,"minAge":18,"maxAge":146,"enrollmentInfo":147,"targetDuration":149,"studyType":71,"phases":4,"briefSummary":150,"conditions":151,"keywords":154,"overallStatus":47,"whyStopped":4,"lastUpdateSubmitDate":159,"lastUpdatePostDateStruct":160,"startDateStruct":161,"completionDateStruct":163,"leadSponsor":165,"locationsCount":167},"100615353","the-investigation-of-kinesiophobia-in-conservative-distal-radius-fractures-100615353","NCT07291505","The Investigation of Kinesiophobia in Conservative Distal Radius Fractures","Investigation of the Predictability of Kinesiophobia on Functional Outcomes in Conservatively Treated Distal Radius Fractures","Inclusion Criteria:\n\n* Having been treated conservatively with an isolated distal radius fracture diagnosis,\n* Having a cognitive level that allows one to understand assessment methods and apply instructions.\n\nExclusion Criteria:\n\n* Comorbid musculoskeletal-neurovascular injuries\n* Bilateral injuries","65 Years",{"count":148,"type":21},34,"18 Weeks","This study aimed to investigate the predictability of kinesiophobia on functional outcomes in conservatively treated patients with distal radius fractures. For this purpose, patients' level of kinesiophobia will be assessed using the Tampa Kinesiophobia Scale. To assess the functional status of patients, joint range of motion and upper extremity weight bearing measurements will be performed. Patients' functionality will be additionally assessed with the Patient Rated Wrist Evaluation Questionnaire.",[152,153,35],"Distal Radius Fracture","Kinesiophobia",[155,156,157,158],"Tampa Scale of Kinesiophobia","distal radius fracture","wrist function","upper extremity weight bearing","2026-03-09",{"date":106,"type":51},{"date":162,"type":51},"2026-02-02",{"date":164,"type":21},"2026-12-30",{"name":166,"class":58},"Pamukkale University",2,{"id":169,"slug":170,"hasResults":11,"nctId":171,"briefTitle":172,"officialTitle":173,"acronym":174,"eligibilityCriteria":175,"healthyVolunteers":176,"sex":17,"minAge":177,"maxAge":4,"enrollmentInfo":178,"targetDuration":4,"studyType":71,"phases":4,"briefSummary":180,"conditions":181,"keywords":189,"overallStatus":47,"whyStopped":4,"lastUpdateSubmitDate":194,"lastUpdatePostDateStruct":195,"startDateStruct":197,"completionDateStruct":199,"leadSponsor":201,"locationsCount":167},"100562510","visual-frailty-in-ageing-100562510","NCT06604104","Visual Frailty in Ageing","Seeing Through Their Eyes - Towards Defining Visual Frailty in Ageing","VFiA","Inclusion Criteria:\n\n* Participants should be residents of Scotland aged 60 years and above with a known diagnosis of advanced AMD.\n* The patients should be receiving treatment from Princess Alexandra Eye Pavilion (PAEP) for at least 6 months and should be responding positively to the treatment. This is to rule out poor results due to either not receiving medication or non-compliance.\n* The participants should be able to provide informed consent before taking part in the study.\n\nExclusion Criteria:\n\n* Participants who cannot speak and read English language will not be included in this pilot study. However, non-English speakers will be included in the future together with interpreters at the validation phase of the developed tool.\n* Participants who have undergone invasive ocular surgery like cataract extraction in their previous visit.\n* The potential participants who fail to provide or do not provide informed consent will not be included in the study.",true,"60 Years",{"count":179,"type":21},20,"The goal of this observational study is to define visual frailty and refine monitoring for an ageing population. It involves piloting a visual frailty assessment tool in a cohort of patients aged 60 and above with a known diagnosis of Age-related Macular Degeneration (AMD) in Princess Alexandra Eye Pavilion (PAEP), Anne Rowling Clinic which is hosting the NHS Low Visual Aid Clinic, or any other NHS Lothian facility treating patients with Age-related Macular Degeneration (AMD). The main questions it aims to answer are:\n\n* What is visual frailty and how can it be assessed or predicted in the global ageing population using visual acuity, reading performance, functional status, mental health and systemic co-morbidities?\n* What is the relationship between visual acuity, reading performance, ocular diagnosis, co-morbidities, mental health, and functional status?\n\nParticipants will have the following data collected from them from either Princess Alexandra Eye Pavilion, Anne Rowling Clinic which is hosting the NHS Low Visual Aid Clinic, or any other NHS Lothian facility treating patients with Age-related Macular Degeneration (AMD):\n\n* Visual acuity (both distance and near)\n* Reading performance\n* Functional status\n* Mental health\n* Co-morbidities\n\nData will also be collected remotely (by phone call) from both the participants and their carers\u002Frelatives about their perceptions of visual frailty.\n\nExpert opinion will be sought from optometrists and ophthalmologists about the concept of visual frailty using an online survey.",[182,183,35,184,185,186,187,188],"Frailty","Age-Related Macular Degeneration","Mental Health","Depression","Anxiety","Cognitive Impairment","Visual Impairment",[190,182,191,192,193],"Visual frailty","Ageing","Reading performance","Age-related Macular Degeneration (AMD)","2026-03-02",{"date":196,"type":51},"2026-03-04",{"date":198,"type":51},"2025-04-09",{"date":200,"type":21},"2027-02",{"name":202,"class":58},"University of Edinburgh",{"id":204,"slug":205,"hasResults":11,"nctId":206,"briefTitle":207,"officialTitle":207,"acronym":208,"eligibilityCriteria":209,"healthyVolunteers":176,"sex":17,"minAge":18,"maxAge":4,"enrollmentInfo":210,"targetDuration":4,"studyType":22,"phases":212,"briefSummary":213,"conditions":214,"keywords":219,"overallStatus":47,"whyStopped":4,"lastUpdateSubmitDate":234,"lastUpdatePostDateStruct":235,"startDateStruct":237,"completionDateStruct":239,"leadSponsor":241,"locationsCount":167},"100501810","red-blood-cell-transfusion-in-ecmo---a-feasibility-trial-100501810","NCT05814094","Red Blood Cell Transfusion in ECMO - A Feasibility Trial","ROSETTA","Inclusion Criteria:\n\n* Patients receiving ECMO\n* Age: 18 years or older\n\nExclusion Criteria:\n\n* Contraindication to RBC transfusion (including known patient preference)\n* Limitations of care put in place either through patient wishes or the treating medical teams\n* ECMO treatment for more than 12 hours. The start of ECMO is defined as the time of initiation of extracorporeal blood flow unless ECMO was initiated during a surgical intervention in which case the start is defined as the arrival time into the initial ICU.\n* The treating physician anticipates that ECMO treatment will cease before the end of tomorrow\n* Where the treating physician deems the study is not in the patient's best interest\n* Where the treating physician has concern regarding patient ability to tolerate restrictive or liberal transfusion trigger thresholds\n* Patients actively listed for a solid organ transplant\n* Patients who are suspected or confirmed to be pregnant\n* Previous ECMO treatment during the same hospital admission",{"count":211,"type":21},120,[24],"Extracorporeal Membrane Oxygenation (ECMO) is an invasive and resource intense treatment used to support critically ill patients who have suffered severe cardiac arrest, cardiac failure or respiratory failure (including severe cases of COVID-19). ECMO acts as a mechanical circulatory support temporarily replacing the function of the heart or lungs by oxygenating blood and removing carbon dioxide, allowing time for these organs to recover. Many critically ill patients, including those on ECMO, have an increased risk of bleeding and reduced production\u002Fincreased destruction of red blood cells (RBCs). This can lead to anaemia (haemoglobin levels \\\u003C120 g\u002Fl), a condition where the body lacks enough healthy RBCs to carry enough oxygen to the body's tissues. Therefore, patients on ECMO frequently require RBC transfusion, with clinicians having to decide if administering an RBC transfusion (with its associated risks) is higher than tolerating complications of anaemia.\n\nROSETTA is a feasibility study that aims to determine the safety and feasibility of randomizing patients on ECMO to a restrictive RBC transfusion strategy (maintain Hb concentration above 70g\u002FL) or to a more liberal transfusion strategy (maintain Hb concentration above 90g\u002FL). Feasibility is defined as the ability to achieve a mean separation of at least 10g\u002FL between the average lowest daily haemoglobin values in the two study groups.",[215,216,217,218,35],"Blood Loss Anemia","Extracorporeal Membrane Oxygenation Complication","Disability Physical","Cognitive Ability, General",[220,221,222,223,224,225,226,227,228,229,230,231,232,233],"Hb","RBC transfusion","ECMO","feasibility","safety","blood transfusion","Australia","blood products","ICU","critical care","intensive care","bleeding","transfusion","Hb values","2025-05-27",{"date":236,"type":51},"2025-05-31",{"date":238,"type":51},"2023-09-20",{"date":240,"type":21},"2025-12-30",{"name":242,"class":58},"Australian and New Zealand Intensive Care Research Centre",{"id":244,"slug":245,"hasResults":11,"nctId":246,"briefTitle":247,"officialTitle":248,"acronym":4,"eligibilityCriteria":249,"healthyVolunteers":176,"sex":17,"minAge":250,"maxAge":4,"enrollmentInfo":251,"targetDuration":4,"studyType":71,"phases":4,"briefSummary":253,"conditions":254,"keywords":259,"overallStatus":47,"whyStopped":4,"lastUpdateSubmitDate":265,"lastUpdatePostDateStruct":266,"startDateStruct":268,"completionDateStruct":270,"leadSponsor":272,"locationsCount":87},"100377980","glucose-variability-and-cognition-in-prediabetes-100377980","NCT04201600","Glucose Variability and Cognition in Prediabetes","Relations of Glucose Variability with Cognitive Function and Functional Status Among Older Adults At Risk for Diabetes","Inclusion Criteria:\n\n* Aged 50 years and older\n* At least 8th grade education\n\nExclusion Criteria:\n\n* Diagnosed type 1 or type 2 diabetes\n* Current use of mediation for diabetes (oral hypoglycemic agents, insulin), or with diabetic properties (e.g., steroids)\n* Chronic disorders (cardiovascular disease, peripheral vascular disease, stroke, transient ischemic attack, chronic kidney disease, past year cancer)\n* Neurological disorders (e.g., Parkinson's, epilepsy, multiple sclerosis)\n* History of dementia or suspected dementia\n* Known HIV\n* Serious mental illness, psychosis, or use of psychotropic medication\n* Heavy alcohol use","50 Years",{"count":252,"type":21},30,"This study examines the association of variability in glucose values over a 10-day period with cognitive function and functional status among individuals with prediabetes, aged 50 or older.",[255,256,35,257,258,185],"Glucose Metabolism Disorders (Including Diabetes Mellitus)","Cognitive Decline","PreDiabetes","Aging",[260,261,262,258,263,264,256],"Glucose Variability","Continuous Glucose Monitoring System (CGMS)","Prediabetes","Physical Functioning","Neurocognition","2025-03-25",{"date":267,"type":51},"2025-03-30",{"date":269,"type":51},"2022-03-01",{"date":271,"type":21},"2026-12-31",{"name":273,"class":58},"University of Maryland, Baltimore",{"id":275,"slug":276,"hasResults":11,"nctId":277,"briefTitle":278,"officialTitle":279,"acronym":280,"eligibilityCriteria":281,"healthyVolunteers":11,"sex":17,"minAge":149,"maxAge":4,"enrollmentInfo":282,"targetDuration":4,"studyType":22,"phases":283,"briefSummary":284,"conditions":285,"keywords":290,"overallStatus":294,"whyStopped":4,"lastUpdateSubmitDate":295,"lastUpdatePostDateStruct":296,"startDateStruct":298,"completionDateStruct":300,"leadSponsor":302,"locationsCount":4},"100583138","the-effect-of-psychosocial-skills-focused-group-psychoeducation-in-schizophrenia-patients-100583138","NCT06872424","The Effect of Psychosocial Skills Focused Group Psychoeducation in Schizophrenia Patients","The Effect of Psychosocial Skills Focused Group Psychoeducation on Functional Improvement, Treatment Compliance and Mental Well-Being in Schizophrenia Patients: a Randomised Controlled Study","Schizophrenia","Inclusion Criteria:\n\n1. Having a diagnosis of schizophrenia according to DSM-5 diagnostic criteria\n2. To have continuity in the Community Mental Health Center\n3. Being in remission (period without psychotic exacerbation) as a result of the evaluation of the outpatient clinic doctor,\n4. To be mentally capable of understanding the questions posed\n5. To have the cognitive competence to understand the training provided\n6. Not having any visual or auditory disability\n7. Graduating from at least primary school\n\nExclusion Criteria:\n\n1. Refusing to participate in the study\n2. Being under 18 years of age\n3. Being illiterate in Turkish\n4. Having Mental Retardation",{"count":148,"type":21},[24],"The aim of this study was to evaluate the effect of psychosocial skills-oriented group psychoeducation on functional recovery, treatment adherence and mental well-being in patients with schizophrenia. This research will be conducted in Giresun Community Mental Health Center. The study was planned as a randomized controlled pretest-posttest design. In addition to the Sociodemographic Information Form prepared by the researchers, the Functional Recovery Scale in Schizophrenia, the Modified Morisky Treatment Adherence Scale and the Warwick-Edinburgh Mental Well-Being Scale will be used to collect the data. The sample size was calculated as 34 people (experimental group= 17, control group= 17). Forms and scales will be applied to the experimental and control groups before psychoeducation and scales will be applied again to both groups after psychoeducation.",[286,287,35,288,289],"Schizophrenia Patients","Psychoeducation","Treatment Outcome","Mental Development",[280,287,291,292,293],"Functional recovery","Treatment adherence","Mental well-being","NOT_YET_RECRUITING","2025-03-10",{"date":297,"type":51},"2025-03-12",{"date":299,"type":21},"2025-04-15",{"date":301,"type":21},"2025-08-15",{"name":303,"class":58},"Gazi University"]