[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"gait-disorder-sensorimotor\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:gait-disorder-sensorimotor":30},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,3,0,[8,61,88],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":15,"eligibilityCriteria":16,"healthyVolunteers":11,"sex":17,"minAge":18,"maxAge":4,"enrollmentInfo":19,"targetDuration":4,"studyType":22,"phases":23,"briefSummary":25,"conditions":26,"keywords":32,"overallStatus":48,"whyStopped":4,"lastUpdateSubmitDate":49,"lastUpdatePostDateStruct":50,"startDateStruct":53,"completionDateStruct":55,"leadSponsor":57,"locationsCount":60},"100621832","spinal-stimulation-with-gait-training-to-improve-lower-limbs-motor-recovery-in-spinal-cord-injury-100621832",false,"NCT07375745","Spinal Stimulation With Gait Training to Improve Lower Limbs Motor Recovery in Spinal Cord Injury","Combined Gait Training and Transcutaneous Spinal Cord Stimulation to Enhance Lower Limbs Motor Recovery After Subacute SCI","CIMELocomotion","Inclusion Criteria:\n\n* paraplegic or quadriplegic participants with a subacute spinal cord injury (sSCI), defined as the stage of spinal cord damage occuring between 1 week and 6 months post-injury\n* above 16 years old\n* have a lesion between C1 - L2\n* be considered as AIS A to D\n* be able to stay at least 10 minutes standing with or without assistance\n* can provide informed consent (no cognitive deficits by MoCA)\n* be able to follow instructions in French or English\n\nExclusion Criteria:\n\n* pacemaker\n* active cancer on stimulation site or metastatic cancer\n* unhealed wound, scar or pain which makes positioning of the electrodes impossible\n* participants with specific contraindications to TMS (epilepsy, non-union cranial fracture and increased intracranial pressure) will be able to participate in the study, but will not receive TMS\n* chronic and severe neuropathic pain\n* pharmacology or implants that may impede with rehabilitation or spinal stimulation\n* pregnancy","ALL","16 Years",{"count":20,"type":21},40,"ESTIMATED","INTERVENTIONAL",[24],"NA","Spinal cord injury (SCI) often results in partial or complete loss of movement. In the subacute phase (\\\u003C 6 months), the central nervous system shows increased potential for neuroplasticity, making it more responsive to rehabilitation and external stimulation. Standard care in rehabilitation centers relies on activity-based therapy (ABT), which uses intensive, task-specific training to promote recovery. Although ABT can improve mobility, its effects are often limited due to the nature of SCI and the indirect activation of neural circuits.\n\nRecent findings suggest that adding transcutaneous spinal cord stimulation (tSCS) to ABT in chronic SCI (\\> 12 months) can enhance lower-limb motor recovery. This study will evaluate whether combining tSCS with gait training is safe and feasible in individuals with subacute SCI and whether it improves lower-limb motor outcomes compared with gait training alone.\n\nThe investigators hypothesize that pairing gait training with tSCS early after injury will be safe and feasible and that tSCS delivered during gait training will augment leg muscle activation and lead to greater functional improvements. The study will also assess the feasibility, safety and tolerability of implementing this combined intervention in a intensive functional rehabilitation setting.",[27,28,29,30,31],"Spinal Cord Injury","Spinal Cord Injury Subacute","Locomotion","Gait Disorder, Sensorimotor","Gait Disorders",[27,33,29,34,35,36,37,38,39,40,41,42,43,44,45,46,47],"Neuromodulation","tSCS","Non-invasive","Transcutaneous","Gait","Transcranial Magnetic Stimulation","Subacute","Artificial Intelligence","AI","Lower Limb","Gait training","Walking","Transcutaneous spinal stimulation","Tonic stimulation","Combined gait training and neuromodulation","NOT_YET_RECRUITING","2026-03-04",{"date":51,"type":52},"2026-03-06","ACTUAL",{"date":54,"type":21},"2026-07-01",{"date":56,"type":21},"2029-07",{"name":58,"class":59},"Centre for Interdisciplinary Research in Rehabilitation of Greater Montreal","OTHER",1,{"id":62,"slug":63,"hasResults":11,"nctId":64,"briefTitle":65,"officialTitle":66,"acronym":4,"eligibilityCriteria":67,"healthyVolunteers":11,"sex":17,"minAge":68,"maxAge":69,"enrollmentInfo":70,"targetDuration":4,"studyType":22,"phases":72,"briefSummary":73,"conditions":74,"keywords":4,"overallStatus":48,"whyStopped":4,"lastUpdateSubmitDate":79,"lastUpdatePostDateStruct":80,"startDateStruct":82,"completionDateStruct":84,"leadSponsor":86,"locationsCount":4},"100621035","pelvic-restricted-vs-pelvic-free-robot-assisted-gait-training-in-stroke-patients-100621035","NCT07365384","Pelvic-Restricted vs. Pelvic-Free Robot-Assisted Gait Training in Stroke Patients","Comparison of Pelvic-Free and Pelvic-Restricted Robot-Assisted Gait Training on Walking Pattern, Balance, and Fear of Falling After Stroke","Inclusion Criteria:\n\n* Age 18 years or older\n* History of stroke more than 6 months prior\n* Presence of hemiplegia-related gait disorder\n* Functional Ambulation Category (FAC) score ≥ 2\n* Ability to walk independently prior to stroke\n\nExclusion Criteria:\n\n* Severe cognitive or communication impairment\n* Movement limitations due to joint contracture or deformity\n* Presence of open wounds or pressure ulcers\n* Uncontrolled hypertension or orthostatic hypotension\n* Severe cardiovascular disease, heart failure, cancer, or serious pulmonary disease\n* High risk of fracture due to severe osteoporosis\n* Gait impairment caused by lower extremity musculoskeletal disorders\n* Severe psychosis\u002Fneurosis\n* Modified Ashworth Scale \\> 3 in the lower extremities (severe spasticity)","18 Years","75 Years",{"count":71,"type":21},36,[24],"This randomized controlled clinical trial aims to compare the effects of pelvic-free versus pelvic-restricted robot-assisted gait training (RAGT) on gait pattern, balance, and fear of falling in stroke patients. Stroke survivors often experience gait impairments, reduced balance, and fear of falling, which limit independence and quality of life. Conventional physiotherapy requires high intensity and repetition but is restricted by therapist capacity. Robotic gait systems provide intensive, repetitive, and safe training; however, most limit pelvic motion, potentially disrupting natural gait patterns and balance strategies.\n\nA total of 36 participants with chronic stroke (≥6 months post-stroke, age ≥18 years, hemiplegic gait disorder, Functional Ambulation Category ≥2) will be randomized into two groups: (1) pelvic-free RAGT plus conventional rehabilitation, or (2) pelvic-restricted RAGT plus conventional rehabilitation. Interventions will consist of 8 RAGT sessions (twice weekly) and 20 conventional rehabilitation sessions (five times weekly) over 4 weeks.\n\nPrimary outcomes include gait analysis parameters (gait speed, step length, cadence, temporal symmetry index) and clinical measures such as the Berg Balance Scale, Functional Ambulation Category, Motricity Index (lower limb), and Falls Efficacy Scale-International. Assessments will be performed at baseline and after 4 weeks of treatment.\n\nThe study hypothesizes that pelvic-free RAGT will improve gait symmetry, balance, and reduce fear of falling more effectively than pelvic-restricted training. Results are expected to provide evidence supporting the integration of pelvic-free robotic gait systems into post-stroke rehabilitation to enhance functional recovery and patient confidence",[75,76,30,77,78],"Stroke","Hemiplegia","Balance Impairment","Fear of Falling","2026-01-23",{"date":81,"type":52},"2026-01-26",{"date":83,"type":21},"2026-01-15",{"date":85,"type":21},"2026-04",{"name":87,"class":59},"Meltem Gunes Akinci",{"id":89,"slug":90,"hasResults":11,"nctId":91,"briefTitle":92,"officialTitle":93,"acronym":4,"eligibilityCriteria":94,"healthyVolunteers":95,"sex":17,"minAge":68,"maxAge":96,"enrollmentInfo":97,"targetDuration":4,"studyType":99,"phases":4,"briefSummary":100,"conditions":101,"keywords":102,"overallStatus":105,"whyStopped":4,"lastUpdateSubmitDate":106,"lastUpdatePostDateStruct":107,"startDateStruct":109,"completionDateStruct":111,"leadSponsor":113,"locationsCount":60},"100367286","gait-parameters-and-balance-in-patients-with-obstructive-lung-diseases-100367286","NCT04062292","Gait Parameters and Balance in Patients With Obstructive Lung Diseases","Investigation of Gait Parameters and Balance in Patients With Obstructive Lung Diseases","Inclusion Criteria for Obstructive Lung Diseases\n\n1. Being diagnosed with obstructive lung disease,\n2. Have not experienced acute exacerbation or infection in the last 1 week,\n3. To be between 18-65 years,\n4. Volunteering for research,\n5. To be able to walk and cooperate.\n\nExclusion Criteria for Obstructive Lung Diseases:\n\n1. Use walking aid or be chronic oxygen support\n2. To have orthopedic or neuromuscular comorbidities that may affect walking patterns.\n3. Having had lung cancer, sarcoidosis, tuberculosis disease or lung surgery.\n\nInclusion Criteria for Healthy People 1.18-65 years of age, 2. Volunteer to participate in the research, 3. To be able to walk and cooperate.\n\nExclusion Criteria for Healthy People\n\n1. Having any cardiopulmonary disease,\n2. To have an advanced orthopedic disease that may affect functional capacity measurement and gait patterns.",true,"65 Years",{"count":98,"type":21},30,"OBSERVATIONAL","In the literature, most of the studies examining the gait characteristics and balance separately or examining the relationship between them are on patients with COPD.\n\nNo study examining gait parameters in other obstructive pulmonary patients such as bronchiectasis and asthma was found.A convincing link between gait disturbances and falls in COPD patients is still unknown and further research is needed. Therefore, the purpose of our study; gait parameters and balance in individuals with obstructive pulmonary disease. We will also examine the relationship between gait parameters and extrapulmonary clinical indicators of these individuals.",[30],[103,104],"balance","chronic obstructive diseases","RECRUITING","2024-08-29",{"date":108,"type":52},"2024-08-30",{"date":110,"type":52},"2019-07-17",{"date":112,"type":21},"2024-12",{"name":114,"class":59},"Hacettepe University"]