[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"gastrointestinal-malignancy\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:gastrointestinal-malignancy":27},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,2,0,[8,46],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":15,"eligibilityCriteria":16,"healthyVolunteers":11,"sex":17,"minAge":18,"maxAge":4,"enrollmentInfo":19,"targetDuration":4,"studyType":22,"phases":23,"briefSummary":25,"conditions":26,"keywords":29,"overallStatus":33,"whyStopped":4,"lastUpdateSubmitDate":34,"lastUpdatePostDateStruct":35,"startDateStruct":38,"completionDateStruct":40,"leadSponsor":42,"locationsCount":45},"100609194","the-erector-spinae-plane-block-for-gastrointestinal-malignancy-pain-treatment-egipt-100609194",false,"NCT07211386","The Erector Spinae Plane Block For Gastrointestinal Malignancy Pain Treatment (EGIPT)","Efficacy of the Erector Spinae Plane Block for Abdominal Pain From Gastrointestinal Malignancies","EGIPT","Inclusion Criteria:\n\n1. Patients age \\> 18 years old with GI malignancy presenting to a Penn Medicine ED with intractable abdominal pain.\n2. Same-day or recent CT scan of the abdomen \u002F pelvis which demonstrates that the patient's abdominal pain can be reasonably attributed to a malignant source.\n\nExclusion Criteria:\n\n1. Allergy to ropivacaine or history of local anesthetic systemic toxicity.\n2. Pregnancy\n3. Incarcerated\n4. Patients being admitted for serial abdominal examinations to determine their surgical course.\n5. Altered mental status or inability for patient to consent for the procedure\n6. Hemodynamic instability\n7. Previously enrolled in the study","ALL","18 Years",{"count":20,"type":21},25,"ESTIMATED","INTERVENTIONAL",[24],"NA","This study will target patients with gastrointestinal (GI) malignancy who present to any of 4 Penn Medicine emergency departments (EDs) with intractable abdominal pain. We will offer eligible patients an erector spinae plane block (ESPB), a regional anesthesia technique which is already offered to such patients in the ED at the University of Pennsylvania Healthy System (UPHS), for their intractable abdominal pain. We will compare the outcomes of this prospective cohort of patients to a matched historical control of patients with GI malignancy who were treated in the ED during the same time period as recruitment, but who were not recruited to partake in the study and who were managed with standard of care. Opioid consumption as measured by total milligram morphine equivalents (MMEs) over a 24-hour period and hospital length of stay (LOS) will be compared between cohorts. Additionally, for the ESPB cohort, pain level pre\u002Fpost ESPB, and functionality and satisfaction with pain management at 24 hours will also be examined.",[27,28],"Gastrointestinal Malignancy","Pain Control",[30,31,32],"Gastrointestinal malignancy","pain control","nerve block","RECRUITING","2025-11-24",{"date":36,"type":37},"2025-11-28","ACTUAL",{"date":39,"type":21},"2025-12-11",{"date":41,"type":21},"2027-06-15",{"name":43,"class":44},"Abramson Cancer Center at Penn Medicine","OTHER",4,{"id":47,"slug":48,"hasResults":11,"nctId":49,"briefTitle":50,"officialTitle":51,"acronym":4,"eligibilityCriteria":52,"healthyVolunteers":11,"sex":17,"minAge":18,"maxAge":4,"enrollmentInfo":53,"targetDuration":4,"studyType":22,"phases":55,"briefSummary":56,"conditions":57,"keywords":4,"overallStatus":33,"whyStopped":4,"lastUpdateSubmitDate":58,"lastUpdatePostDateStruct":59,"startDateStruct":61,"completionDateStruct":63,"leadSponsor":65,"locationsCount":67},"100557476","the-5-fu-holter-study-100557476","NCT06538610","The 5-FU Holter Study","Feasibility Study of Ambulatory Holter Monitoring While Receiving Infusional Fluorouracil (5-FU) Chemotherapy","Inclusion Criteria:\n\n* Patients with diagnosis of gastrointestinal malignancy\n* Planned to receive either FOLFOX chemotherapy with any treatment intent\n* Aged ≥ 18 years at time of signing informed consent form\n\nExclusion Criteria:\n\n• ECG with left bundle branch block or left ventricular hypertrophy with strain",{"count":54,"type":21},10,[24],"To assess the feasibility of using ambulatory ECG monitoring (Holter monitor) for patients receiving 5-FU chemotherapy",[27],"2024-12-04",{"date":60,"type":37},"2024-12-09",{"date":62,"type":37},"2024-11-01",{"date":64,"type":21},"2026-01",{"name":66,"class":44},"University of Auckland, New Zealand",1]