[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"gastrointestinal-motility-disorder\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:gastrointestinal-motility-disorder":25},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,3,0,[8,45,72],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":13,"acronym":14,"eligibilityCriteria":15,"healthyVolunteers":11,"sex":16,"minAge":17,"maxAge":18,"enrollmentInfo":19,"targetDuration":4,"studyType":22,"phases":4,"briefSummary":23,"conditions":24,"keywords":28,"overallStatus":32,"whyStopped":4,"lastUpdateSubmitDate":33,"lastUpdatePostDateStruct":34,"startDateStruct":37,"completionDateStruct":39,"leadSponsor":41,"locationsCount":44},"100378536","ivig-for-drug-and-device-refractory-gastrointestinal-auto-immune-neuropathy-100378536",false,"NCT04208828","IVIG for Drug and Device Refractory Gastrointestinal Auto-Immune Neuropathy","GAIN","Inclusion Criteria: Patient with otherwise refractory symptoms of gastrointestinal (GI) motor disorders.\n\n\\-\n\nExclusion Criteria: Inability to receive intravenous immunoglobulin.\n\n\\-","ALL","12 Years","90 Years",{"count":20,"type":21},400,"ESTIMATED","OBSERVATIONAL","Patients with the symptoms of generalized GI dysmotility, including gastroparesis, are sometimes refractory to available medications, devices and other interventions\u002F Some of these patients have serologic and\u002For endo organ abnormalities and findings consistent with autoimmune neuropathies, primarily involving the GI tract. These disorders have been known as autoimmune gastrointestinal neuropathies (GAIN) or also as autoimmune gastrointestinal dysmotility (AGID), among other terms. Some patients respond to intravenous immunoglobulin (IVIG) and this study, which is an observational clinical series, documents the patients, their findings and standardized responses to therapy with IVIG.",[25,26,27],"Gastrointestinal Motility Disorder","Gastroparesis","Neuropathy",[26,29,30,31,27],"Nausea","Vomiting","Abdominal Pain","RECRUITING","2025-07-29",{"date":35,"type":36},"2025-08-01","ACTUAL",{"date":38,"type":36},"2020-01-02",{"date":40,"type":21},"2028-01-02",{"name":42,"class":43},"University of Louisville","OTHER",1,{"id":46,"slug":47,"hasResults":11,"nctId":48,"briefTitle":49,"officialTitle":49,"acronym":50,"eligibilityCriteria":51,"healthyVolunteers":11,"sex":16,"minAge":52,"maxAge":4,"enrollmentInfo":53,"targetDuration":4,"studyType":55,"phases":56,"briefSummary":58,"conditions":59,"keywords":4,"overallStatus":32,"whyStopped":4,"lastUpdateSubmitDate":63,"lastUpdatePostDateStruct":64,"startDateStruct":66,"completionDateStruct":68,"leadSponsor":70,"locationsCount":44},"100515304","interrogating-the-pathophysiological-mechanisms-of-constipation-in-patients-with-systemic-sclerosis-100515304","NCT05989763","Interrogating the Pathophysiological Mechanisms of Constipation in Patients With Systemic Sclerosis","TEA in SSc","Inclusion Criteria\n\n* Patients with SSc-constipation from Aim 1 of the study\n* Patients with SCT (\\>20% radiopaque marks left in the colon 5 days (120 hours) after swallowing the Sitzmark capsule or patients with RH (defined in Aim 1)\n* Patients not yet on therapy for constipation or patients who continue to experience constipation while on stable therapy for one month prior to TEA.\n\nExclusion Criteria\n\n-Patients with symptoms of both diarrhea and constipation but not predominantly symptoms of constipation.","18 Years",{"count":54,"type":21},60,"INTERVENTIONAL",[57],"NA","The purpose of this study is to determine whether transcutaneous electrical acustimulation (TEA) alters systemic sclerosis (SSc)-related colonic and anorectal physiology by enhancing autonomic nervous system (ANS) function. The study will examine the effects of TEA on slow colonic transit (SCT) and rectal hyposensitivity (RH), to examine whether TEA improves autonomic dysfunction and modulates inflammatory pathways.",[60,61,25,62],"Systemic Sclerosis","Constipation","Autonomic Dysfunction","2025-06-21",{"date":65,"type":36},"2025-06-26",{"date":67,"type":36},"2024-02-17",{"date":69,"type":21},"2029-09-01",{"name":71,"class":43},"The University of Texas Health Science Center, Houston",{"id":73,"slug":74,"hasResults":11,"nctId":75,"briefTitle":76,"officialTitle":77,"acronym":78,"eligibilityCriteria":79,"healthyVolunteers":11,"sex":16,"minAge":52,"maxAge":4,"enrollmentInfo":80,"targetDuration":4,"studyType":55,"phases":82,"briefSummary":83,"conditions":84,"keywords":87,"overallStatus":32,"whyStopped":4,"lastUpdateSubmitDate":92,"lastUpdatePostDateStruct":93,"startDateStruct":95,"completionDateStruct":97,"leadSponsor":99,"locationsCount":44},"100564578","the-effect-of-abdominal-massage-on-gastrointestinal-functions-in-mechanically-ventilated-patients-receiving-enteral-nutrition-in-intensive-care-100564578","NCT06631001","\"The Effect of Abdominal Massage on Gastrointestinal Functions in Mechanically Ventilated Patients Receiving Enteral Nutrition in Intensive Care\"","The Effect of Abdominal Massage on Gastrointestinal Functions in Mechanically Ventilated Patients Receiving Enteral Nutrition in Intensive Care","AMGF-ICU","Inclusion Criteria:\n\n* Patients over 18 years of age.\n* Patients who have been intubated and are on enteral feeding for at least 5 days.\n* Patients without wounds on the extremities or abdominal area.\n* Patients without a history of surgical intervention or radiotherapy in the abdominal area.\n* Patients without current gastrointestinal symptoms (constipation, diarrhea, vomiting, abdominal distension, or increased gastric residual volume).\n* Patients without intestinal obstruction.\n* Patients who have given consent through a first-degree relative.\n* Patients with no contraindications for abdominal massage.\n* Glasgow Coma Scale GCS \\> 3.\n* Acute Physiology and Chronic Health Evaluation (APACHE II) score \\> 16\n\nExclusion Criteria:\n\n* Patients receiving intermittent enteral nutrition\n* Patients not on mechanical ventilation\n* Patients with contraindications for abdominal massage\n* Patients fed via Percutaneous Endoscopic Gastrostomy\n* Patients who were intubated later\n* Patients hospitalized due to postoperative reasons",{"count":81,"type":21},70,[57],"This study aims to evaluate the effects of abdominal massage on gastrointestinal functions in mechanically ventilated patients receiving enteral nutrition in intensive care units.",[85,25,86],"Defecation Disorder","Gastrointestinal Motility and Defecation Conditions",[88,86,89,90,91],"Abdominal massage","Gastrointestinal Motility","Intensive care","enteral nutrition","2025-02-15",{"date":94,"type":36},"2025-02-19",{"date":96,"type":36},"2025-01-06",{"date":98,"type":21},"2025-08-29",{"name":100,"class":43},"Mersin University"]