[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"gastrointestinal-neoplasm-malignant\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:gastrointestinal-neoplasm-malignant":26},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,2,0,[8,47],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":4,"eligibilityCriteria":15,"healthyVolunteers":11,"sex":16,"minAge":17,"maxAge":4,"enrollmentInfo":18,"targetDuration":4,"studyType":21,"phases":22,"briefSummary":24,"conditions":25,"keywords":28,"overallStatus":34,"whyStopped":4,"lastUpdateSubmitDate":35,"lastUpdatePostDateStruct":36,"startDateStruct":39,"completionDateStruct":41,"leadSponsor":43,"locationsCount":46},"100557035","telephone-support-in-advanced-gastrointestinal-cancer-100557035",false,"NCT06532877","Telephone Support in Advanced Gastrointestinal Cancer","Telephone Support Program for Patients With Advanced Gastrointestinal Cancer and Their Family Caregivers","Patient Inclusion Criteria:\n\n* Patient is at least 3 weeks post-diagnosis of unresectable stage III or stage IV gastrointestinal cancer (i.e., ampullary, anal, appendix, bile duct, colon, esophageal, gallbladder, liver, pancreatic, rectal, small intestine, or stomach cancer) and is receiving cancer care at one of the study sites.\n* Patient is at least 18 years of age.\n* Patient can speak and read English.\n* Patient has an eligible, consenting family caregiver (see criteria below).\n* Patient has moderate to severe fatigue interference with functioning.\n\nPatient Exclusion Criteria:\n\n* Patient shows significant psychiatric or cognitive impairment that would preclude providing informed consent and study participation.\n* Patient reports being able to do little activity on a functional status measure.\n* Patient is receiving hospice care at screening.\n* Patient does not have working phone service.\n* Patient has hearing impairment that precludes participation.\n* Patient participated in the pilot trial testing the same intervention.\n\nCaregiver Inclusion Criteria:\n\n* Family caregiver identified by a gastrointestinal cancer patient who meets the eligibility criteria.\n* Caregiver has significant caregiving burden.\n* Caregiver lives with the patient or has visited the patient in-person at least twice a week for the past month.\n* Caregiver is at least 18 years of age.\n* Caregiver can speak and read English.\n\nCaregiver Exclusion Criteria:\n\n* Caregiver shows significant psychiatric or cognitive impairment that would preclude providing informed consent and study participation.\n* Caregiver does not have working phone service.\n* Caregiver has hearing impairment that precludes participation.\n* Patient declines study participation.","ALL","18 Years",{"count":19,"type":20},488,"ESTIMATED","INTERVENTIONAL",[23],"NA","The goal of this clinical trial is to see if telephone support programs help patients and their family caregivers adjust to advanced gastrointestinal cancer. A new telephone counseling program that involves practicing strategies for managing stress and symptoms will be compared to a telephone program involving education on quality-of-life issues and psychosocial support. The main questions it aims to answer are:\n\nDoes our telephone counseling program lower the negative impact of patients' fatigue on their activities, emotions, and thinking abilities compared to a telephone program involving education and support? Does our telephone counseling program lower family caregivers' feelings of burden compared to a telephone program involving education and support?\n\nParticipants in both study conditions will:\n\nComplete 6 weekly telephone sessions of counseling or education\u002Fsupport Complete a telephone booster session Complete 3 telephone interviews over about 5 months",[26,27],"Gastrointestinal Neoplasm Malignant","Caregiver Burden",[29,30,31,32,33,27],"Gastrointestinal Neoplasms","Family Caregivers","Acceptance and Commitment Therapy","Fatigue","Psychotherapy","RECRUITING","2026-01-22",{"date":37,"type":38},"2026-01-23","ACTUAL",{"date":40,"type":38},"2024-08-21",{"date":42,"type":20},"2029-02",{"name":44,"class":45},"Indiana University","OTHER",4,{"id":48,"slug":49,"hasResults":11,"nctId":50,"briefTitle":51,"officialTitle":52,"acronym":4,"eligibilityCriteria":53,"healthyVolunteers":11,"sex":16,"minAge":17,"maxAge":4,"enrollmentInfo":54,"targetDuration":4,"studyType":21,"phases":56,"briefSummary":57,"conditions":58,"keywords":59,"overallStatus":34,"whyStopped":4,"lastUpdateSubmitDate":64,"lastUpdatePostDateStruct":65,"startDateStruct":67,"completionDateStruct":69,"leadSponsor":71,"locationsCount":74},"100516277","treatment-recommendations-for-gastrointestinal-cancers-via-large-language-models-100516277","NCT06002425","Treatment Recommendations for Gastrointestinal Cancers Via Large Language Models","Application of Large Language Models in the Recommendation of Treatment Plans for Gastrointestinal Cancers","Inclusion Criteria:\n\n* Age ≥18 years, both male and female.\n* Pathologically confirmed diagnosis of gastrointestinal cancer (gastric cancer or colorectal Cancer).\n* Detailed medical records available prior to treatment (including chief complaint, history of present illness, radiological examinations, pathological examinations, laboratory tests, etc.).\n* Participants will receive complete treatment in the participating hospitals.\n\nExclusion Criteria:\n\n* Participants with cancers other than gastrointestinal cancers.\n* Participants who receive treatment in multiple hospitals.",{"count":55,"type":20},400,[23],"This study will evaluate the utility of ChatGPT in recommending treatment plans for patients with gastrointestinal cancers, using both retrospective and prospective data.",[26],[60,61,62,63],"Artificial Intelligence","Large Language Model","Gastrointestinal Cancers","Treatment Recommendation","2023-09-06",{"date":66,"type":38},"2023-09-08",{"date":68,"type":38},"2023-08-29",{"date":70,"type":20},"2028-12-31",{"name":72,"class":73},"Chinese Academy of Sciences","OTHER_GOV",7]