[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"gastroparesis-like-syndrome\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:gastroparesis-like-syndrome":28},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,1,0,[8],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":15,"eligibilityCriteria":16,"healthyVolunteers":11,"sex":17,"minAge":18,"maxAge":19,"enrollmentInfo":20,"targetDuration":23,"studyType":24,"phases":4,"briefSummary":25,"conditions":26,"keywords":29,"overallStatus":32,"whyStopped":4,"lastUpdateSubmitDate":33,"lastUpdatePostDateStruct":34,"startDateStruct":37,"completionDateStruct":39,"leadSponsor":41,"locationsCount":44},"100514653","gpcrc-pediatric-gastroparesis-registry-2-100514653",false,"NCT05981300","GpCRC Pediatric Gastroparesis Registry 2","GpCRC Pediatric Gastroparesis Registry 2: Characterization and Clinical Course of Symptoms and Gastric Emptying in Pediatric, Adolescent, and Young Adult Participants With Symptoms of Gastroparesis","PGpR2","Inclusion Criteria:\n\n* Provision of signed and dated informed consent form and assent, as age appropriate.\n* Stated willingness to comply with all study procedures and availability for the duration of the study\n* 8 to 25 years of age at the time of enrollment\n* Symptoms of Gp of at least 12 weeks duration: constellation of some combination of:\n\nnausea, vomiting, early satiety, postprandial fullness; symptoms sometimes may be accompanied by upper abdominal pain\n\n* Have undergone a gastric emptying scintigraphic study of solids using 4-hour Egg Beaters protocol (or equivalent generic liquid egg white meal) within the last 12 months who fall into one of the two categories:\n* Delayed gastric emptying-defined as an abnormal 2-hour (\\>60% retention) and\u002For 4- hour (\\>10% retention) result based on a 4-hour scintigraphic gastric emptying study\n* Gastric emptying that is not delayed but who have symptoms of Gp (designated in this study as GLS) or have previously participated in the Pediatric Gastroparesis Registry (PGpR) study\n* An etiology of either diabetic or idiopathic Gp or GLS\n\nExclusion Criteria:\n\n* Inability to comply with or complete the scintigraphic gastric emptying test (including allergy to eggs)\n* Pregnancy\n* Autism spectrum disorder, significant developmental delay, psychosis (because of inability to complete questionnaires)\n* Use of narcotic analgesics greater than three days per week.\n* Presence of conditions associated with GI mucosal disease (e.g., inflammatory bowel disease, known eosinophilic gastroenteritis or eosinophilic esophagitis, gastric ulcer, peptic ulcer, celiac disease)\n* Presence of any other condition that could case delayed gastric emptying\n* Gastrointestinal construction confirmed by upper endoscopy (EGD), upper gastrointestinal series (UGI), or abdominal CT\n* Primary neurological conditions that can cause nausea and vomiting such as increased intracranial pressure, space occupying or inflammatory\u002Finfectious legions\n* Acute or chronic renal failure (abnormal creatinine for age) and \u002For on hemodialysis or peritoneal dialysis\n* Acute liver failure\n* Advanced liver disease (features of portal hypertension)\n* Clinically significant congenital heart disease (i.e., vaginal injury during cardiac repair)\n* History of esophageal, gastric or bowel surgery.\n* Metabolic disease including mitochondrial disease and inborn errors of metabolism\n* Chronic lung disease (including cystic fibrosis)\n* A serious chronic medical condition (e.g., inflammatory bowel disease)\n* Use of medications that can affect motility during the gastric emptying study\n* Any other condition, which in the option of the investigator, could explain the symptoms or could interfere with study requirements.","ALL","8 Years","25 Years",{"count":21,"type":22},216,"ESTIMATED","3 Years","OBSERVATIONAL","The objective of the Pediatric Gastroparesis Registry 2 is to create a national prospective registry of children, adolescents, and young adults with gastroparesis and gastroparesis-like syndrome (symptoms of gastroparesis but normal gastric emptying).",[27,28],"Gastroparesis","Gastroparesis-like Syndrome",[30,31],"Functional Disorder of Gastrointestinal Tract","Gastro-Intestinal Disorder","RECRUITING","2026-03-30",{"date":35,"type":36},"2026-04-03","ACTUAL",{"date":38,"type":36},"2024-12-18",{"date":40,"type":22},"2027-04-30",{"name":42,"class":43},"Johns Hopkins Bloomberg School of Public Health","OTHER",6]