[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"gave---gastric-antral-vascular-ectasia\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:gave---gastric-antral-vascular-ectasia":25},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,1,0,[8],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":15,"eligibilityCriteria":16,"healthyVolunteers":11,"sex":17,"minAge":18,"maxAge":4,"enrollmentInfo":19,"targetDuration":4,"studyType":22,"phases":4,"briefSummary":23,"conditions":24,"keywords":26,"overallStatus":28,"whyStopped":4,"lastUpdateSubmitDate":29,"lastUpdatePostDateStruct":30,"startDateStruct":33,"completionDateStruct":35,"leadSponsor":37,"locationsCount":4},"100579901","study-on-the-efficacy-of-endoscopic-radiofrequency-treatment-in-reducing-the-need-for-blood-transfusions-in-gave-100579901",false,"NCT06830317","Study on the Efficacy of Endoscopic Radiofrequency Treatment in Reducing the Need for Blood Transfusions in GAVE","A Multicenter, Observational, Prospective Study on the Efficacy of Endoscopic Radiofrequency Treatment in Reducing the Need for Blood Transfusions Compared with Conventional Therapies in Patients with Gastric Antral Vascular Ectasia (GAVE)","GAVE","Inclusion Criteria:\n\n* At least 18 years of age\n* Existing diagnosis of GAVE (validated by an external expert)\n* Melena and\u002For hematemesis secondary to GAVE and\u002For iron deficiency anemia persisting despite systemic iron therapy or oral supplementation and\u002For (concentrated red globules) GRC transfusions for at least 6 months\n* Negative colonoscopy (performed within 12 months prior to enrollment, exclusion of any site of bleeding)\n* Able to comply with study requirements and understand and sign the informed consent form\n\nExclusion Criteria:\n\n* Alternative causes for iron deficiency anemia (gastro-duodenal erosions and\u002For ulcerations, celiac disease, Inflammatory Bowel Disease (IBD), etc)\n* Pregnancy\n* Active malignancy (malignancy diagnosed in past five years or ongoing treatment)\n* Anatomical malformations precluding treatment with RFA\n* Blood coagulation deficit: International normalized ratio (INR)\\>2, Platelets (PLT) \\\u003C50,000","ALL","18 Years",{"count":20,"type":21},80,"ESTIMATED","OBSERVATIONAL","The aim of the study therefore is to permanently resolve the existence of the bleeding sites caused by Gave and reduce both bleeding episodes and the need for transfusion in such patients applying \"Barrx\" (trademark) radiofrequency endoscopic ablation technology in selected cohort of patients that will be defined the patient inclusion section.",[25],"GAVE - Gastric Antral Vascular Ectasia",[27],"GAVE, RADIOFREQUENCY TREATMENT, BLOOD TRANSFUSION","NOT_YET_RECRUITING","2025-02-11",{"date":31,"type":32},"2025-02-17","ACTUAL",{"date":34,"type":21},"2025-04-02",{"date":36,"type":21},"2027-09-02",{"name":38,"class":39},"Azienda Ospedaliera Specializzata in Gastroenterologia Saverio de Bellis","OTHER"]