[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"gender-affirmation-surgery\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:gender-affirmation-surgery":30},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,3,0,[8,50,82],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":15,"eligibilityCriteria":16,"healthyVolunteers":17,"sex":18,"minAge":19,"maxAge":20,"enrollmentInfo":21,"targetDuration":4,"studyType":24,"phases":25,"briefSummary":27,"conditions":28,"keywords":34,"overallStatus":37,"whyStopped":4,"lastUpdateSubmitDate":38,"lastUpdatePostDateStruct":39,"startDateStruct":42,"completionDateStruct":44,"leadSponsor":46,"locationsCount":49},"100521762","the-role-of-amnion-membrane-allografts-in-nipple-preservation-100521762",false,"NCT06073808","The Role of Amnion Membrane Allografts in Nipple Preservation","The Role of Amnion Membrane Allografts in Nipple Preservation After Nipple Sparing Mastectomy: A Double-Blinded Randomized Controlled Trial","AmnioFix","Inclusion Criteria:\n\n* Biologically female with documented diagnosis of gender dysphoria, desire to undergo gender affirming surgery (female-to-male) NSM, and age 15 years of age or older.\n* Biological female, age 18 to 75 years old, who desire to undergo bilateral prophylactic NSM for nonmalignant breast conditions or to reduce the risk of breast cancer.\n\nExclusion Criteria:\n\n* Current steroid use\n* Known connective tissue disorder\n* Known neuropathy\n* Known history of breast cancer\n* History of breast radiotherapy\n* Pregnant or nursing",true,"ALL","15 Years","75 Years",{"count":22,"type":23},30,"ESTIMATED","INTERVENTIONAL",[26],"NA","The overall objective of this proposal is to conduct a randomized-controlled study to determine whether treatment with dehydrated human amnion\u002Fchorion membrane (dHACMs) allografts can improve NAC viability in patients undergoing nipple sparing mastectomy (NSM). dHACM allografts are commercially available tissue membranes with biocompatible extracellular matrix and growth factors that have been shown to improve wound healing in patients with chronic and lower extremity wounds. To date, no study has evaluated the impact of dHACMs on NAC preservation following NSM. Investigators hypothesize that subareolar surgical implantation of dHACM allografts at time of NSM will reduce NAC necrosis and improve viability.",[29,30,31,32,33],"Mastectomy","Gender Affirmation Surgery","Nipple Sparing Mastectomy","Prophylactic Mastectomy","Benign Breast Condition",[35,36],"nipple sparing mastectomy","gender affirming surgery","NOT_YET_RECRUITING","2026-04-24",{"date":40,"type":41},"2026-04-30","ACTUAL",{"date":43,"type":23},"2026-06-01",{"date":45,"type":23},"2026-09",{"name":47,"class":48},"Stanford University","OTHER",1,{"id":51,"slug":52,"hasResults":11,"nctId":53,"briefTitle":54,"officialTitle":54,"acronym":55,"eligibilityCriteria":56,"healthyVolunteers":17,"sex":57,"minAge":58,"maxAge":59,"enrollmentInfo":60,"targetDuration":62,"studyType":63,"phases":4,"briefSummary":64,"conditions":65,"keywords":68,"overallStatus":72,"whyStopped":4,"lastUpdateSubmitDate":73,"lastUpdatePostDateStruct":74,"startDateStruct":76,"completionDateStruct":78,"leadSponsor":80,"locationsCount":49},"100603034","evaluating-sexual-functioning-in-trans-men-during-the-gender-affirmation-process-a-mixed-methods-study-100603034","NCT07131267","Evaluating Sexual Functioning in Trans Men During the Gender Affirmation Process: A Mixed Methods Study","ESFTMGAP","Inclusion Criteria:\n\n18 years or older Diagnosed with gender dysphoria by two different physicians Getting medical support for the gender affirmation process\n\nExclusion Criteria:\n\nOver 65 years Diagnosed with intellectual disability, dementia, or organic mental disorders Having a systemic disease that negatively impacts sexual function Getting a score above 3 on the Clinical Global Impression Scale","FEMALE","18 Years","65 Years",{"count":61,"type":23},52,"1 Day","OBSERVATIONAL","Both sexual experiences and the process of gender transition initiated to reduce gender dysphoria carry cultural characteristics. Gender categories, societal expectations for each gender, and attitudes toward sexual minorities in a given society can shape the lived experiences of trans individuals. Therefore, research on individuals with gender dysphoria in different cultural contexts is of great importance. To our knowledge, no study in Türkiye has examined sexual functioning in trans individuals undergoing gender transition. For this reason, our study aimed to investigate how sexual functioning is affected by the gender transition process in trans men with gender dysphoria, using both quantitative and qualitative methods.",[66,67,30],"Sexual Functioning","Transgender Men",[69,70,71],"sexual functioning","transgender men","gender affirmation","RECRUITING","2025-08-19",{"date":75,"type":41},"2025-08-20",{"date":77,"type":41},"2025-08-05",{"date":79,"type":23},"2026-12-31",{"name":81,"class":48},"Eskisehir Osmangazi University",{"id":83,"slug":84,"hasResults":11,"nctId":85,"briefTitle":86,"officialTitle":86,"acronym":4,"eligibilityCriteria":87,"healthyVolunteers":11,"sex":57,"minAge":58,"maxAge":4,"enrollmentInfo":88,"targetDuration":4,"studyType":63,"phases":4,"briefSummary":90,"conditions":91,"keywords":100,"overallStatus":37,"whyStopped":4,"lastUpdateSubmitDate":104,"lastUpdatePostDateStruct":105,"startDateStruct":107,"completionDateStruct":109,"leadSponsor":111,"locationsCount":49},"100570688","histological-results-in-transgender-individuals-assigned-to-females-at-birth-undergoing-gender-affirmation-surgery-and-in-testosterone-therapy-100570688","NCT06710496","HISTOLOGICAL RESULTS IN TRANSGENDER INDIVIDUALS ASSIGNED TO FEMALES AT BIRTH UNDERGOING GENDER AFFIRMATION SURGERY AND IN TESTOSTERONE THERAPY","Inclusion Criteria:\n\n* gender incongruence diagnosis\n* people assigned female at birth\n* age \\>18 years\n* gender affirming surgery with hysterectomy\n* testosterone therapy\n\nExclusion Criteria:\n\n* previous gynecological surgery\n* previous gynecological disorder diagnosis",{"count":89,"type":23},100,"The aim of this study is to report histological results of genital organs removed during gender affirmg surgery in transgender people assigned female at birth (AFAB), to increase the knowledge about the long-term effects of gender affirming hormone therapy with testosterone on these organs and to evaluate the incidence of benign and malign gynecological pathology in AFAB transgender people.",[92,93,94,95,96,97,67,30,98,99],"Pregnancy","Smoking Behavior","Testosterone Replacement Therapy","Drugs","Comorbidities and Coexisting Conditions","Gynecological Surgery","Hormone Replacement Therapy","Gynecological Disorders",[101,102,103],"transgender","afab","histology","2024-11-26",{"date":106,"type":41},"2024-11-29",{"date":108,"type":23},"2024-12",{"date":110,"type":23},"2025-12",{"name":112,"class":48},"IRCCS Azienda Ospedaliero-Universitaria di Bologna"]