[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"gender\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:gender":28},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,7,0,[8,51,83,107,134,160,182],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":15,"eligibilityCriteria":16,"healthyVolunteers":11,"sex":17,"minAge":18,"maxAge":19,"enrollmentInfo":20,"targetDuration":23,"studyType":24,"phases":4,"briefSummary":25,"conditions":26,"keywords":30,"overallStatus":38,"whyStopped":4,"lastUpdateSubmitDate":39,"lastUpdatePostDateStruct":40,"startDateStruct":43,"completionDateStruct":45,"leadSponsor":47,"locationsCount":50},"100550044","prospective-multicenter-registry-of-gender-diversity-and-inclusion-gedi-of-women-with-acute-coronary-syndrome-100550044",false,"NCT06441942","Prospective Multicenter Registry of Gender, Diversity and Inclusion (GEDI) of Women With Acute Coronary Syndrome","Creation of a Prospective Multicenter Registry of Gender, Diversity and Inclusion (GEDI) in Phenotypic and Genetic Characterization of Acute Coronary Syndrome.","ACS GEDI","Inclusion Criteria:\n\n* Women \\>\u002F= 18 years with ACS (STEMI, NSTEMI or Unstable Angina).\n\nExclusion Criteria:\n\n* age \\\u003C 18 years and\u002For unwillingness to sign informed consent and\u002For unwillingness to make follow-up visits","FEMALE","18 Years","100 Years",{"count":21,"type":22},100,"ESTIMATED","12 Months","OBSERVATIONAL","Create a multicenter prospective registry that collects information from women affected by acute coronary syndrome (ACS). This registry aims to understand the diversity in the presentation of women with ACS. It proposes to conduct a thorough characterization of the women involved in the study through genetic, biochemical, and molecular analysis.This approach aims to identify any differences in the characteristics of women with ACS and to identify disease subtypes that may influence treatment options and clinical outcomes.",[27,28,29],"Acute Coronary Syndrome","Gender","Genetic Predisposition",[31,32,33,34,35,36,37],"ACS","GEDI","Genetic","DNA","mRNA","Proteomic","Metabolomic","RECRUITING","2026-03-30",{"date":41,"type":42},"2026-04-03","ACTUAL",{"date":44,"type":42},"2025-01-28",{"date":46,"type":22},"2027-02-28",{"name":48,"class":49},"IRCCS San Raffaele","OTHER",4,{"id":52,"slug":53,"hasResults":11,"nctId":54,"briefTitle":55,"officialTitle":56,"acronym":4,"eligibilityCriteria":57,"healthyVolunteers":11,"sex":58,"minAge":18,"maxAge":4,"enrollmentInfo":59,"targetDuration":4,"studyType":61,"phases":62,"briefSummary":64,"conditions":65,"keywords":69,"overallStatus":38,"whyStopped":4,"lastUpdateSubmitDate":73,"lastUpdatePostDateStruct":74,"startDateStruct":76,"completionDateStruct":78,"leadSponsor":80,"locationsCount":82},"100590313","study-on-sex-specific-individualized-dose-calculation-of-contrast-agent-in-ct-examinations-100590313","NCT06965790","Study on Sex-specific, Individualized Dose Calculation of Contrast Agent in CT Examinations","Randomized Controlled Study on Sex-specific, Individualized Dose Calculation of Intravenously Administered Contrast Agent in CT Examinations in Portal Venous Phase to Achieve Equivalent Contrast in Men and Women","Inclusion Criteria:\n\n* Presence of a justifying indication for a CT scan of the thorax and abdomen with application of intravenous contrast medium and a start delay corresponding to the portal venous contrast medium phase\n* Ability to give informed consent, as well as written and verbal consent to participate in the study available\n\nExclusion Criteria:\n\n* Cardiorespiratory instability (as assessed by the attending physician)\n* Age \\\u003C18 years\n* Existing or suspected pregnancy\n* Known post hepatectomy and\u002For splenectomy\n* Lack of current height (in the same inpatient\u002Foutpatient hospital stay) or lack of possibility of height measurement\n* Lack of current daily body weight or inability to measure body weight\n* Height under 140 cm or over 220 cm\n* Body weight under 50 kg or over 120 kg\n* Contraindication to iodine-containing contrast medium (Allergy to contrast media containing iodine, Severe renal insufficiency (eGFR \\\u003C 30 ml\u002Fmin), Hyperthyroidism)","ALL",{"count":60,"type":22},400,"INTERVENTIONAL",[63],"NA","A large proportion of radiological CT examinations require the intravenous administration of iodine-containing X-ray contrast medium. According to current guidelines, the amount required for CT examinations in the (portal) venous phase is calculated on the basis of body weight (e.g. 0.2-0.4 g iodine\u002Fkg body weight), but a standardized application dose of the contrast agent is often also used.\n\nIn earlier studies, the investigators found that the iodine contrast in vessels and organs achieved with a standardized amount of contrast agent differs significantly between women and men. On average, women showed around 10% higher iodine contrast than men of the same height and weight. The investigators attribute these differences to physiological, sex-specific differences in blood volume. For example, the blood volume of a woman 175 cm tall and weighing 75 kg is approx. 400 ml less than that of a man of the same height and weight (approx. 4.6 vs. 5.0 l, calculated according to Nadler). Taking blood volume into account, sex was no longer a significant influencing factor in a retrospective cohort (n=274).\n\nThe investigators would now like to investigate these results in a prospective study. For this purpose, two groups of patients with a clinical indication for a contrast-enhanced CT scan in the venous phase will be compared:\n\n1. control group with regular weight-adjusted (n = 200)\n2. study group with dosing according to blood volume (n = 200).\n\nThe hypothesis is that the application scheme adapted to the blood volume leads to a more homogeneous contrasting of women and men. In order to quantify this effect, the iodine contrast values of both groups will be quantitatively analyzed, taking into account other influencing variables (height, weight).\n\nThe investigators hope that this approach will reduce or even eliminate the observed sex-specific differences. This would lead to a sex-equal contrast based on an individualized amount of contrast medium.",[66,67,28,68],"CT Scans","Contrast Media","Womens Health",[70,66,67,71,72],"CT","contrast","gender","2025-12-07",{"date":75,"type":42},"2025-12-09",{"date":77,"type":42},"2025-04-01",{"date":79,"type":22},"2027-03",{"name":81,"class":49},"University Hospital Augsburg",1,{"id":84,"slug":85,"hasResults":11,"nctId":86,"briefTitle":87,"officialTitle":88,"acronym":4,"eligibilityCriteria":89,"healthyVolunteers":11,"sex":58,"minAge":90,"maxAge":4,"enrollmentInfo":91,"targetDuration":93,"studyType":24,"phases":4,"briefSummary":94,"conditions":95,"keywords":4,"overallStatus":38,"whyStopped":4,"lastUpdateSubmitDate":98,"lastUpdatePostDateStruct":99,"startDateStruct":101,"completionDateStruct":103,"leadSponsor":105,"locationsCount":82},"100396335","barts-minoca-registry-100396335","NCT04440761","Barts-MINOCA Registry","Barts Myocardial Infarction With Non-Obstructed Coronary Arteries (MINOCA) Registry","Inclusion Criteria:\n\n* Both male and female patients ≥16 years of age will be included\n* All patients will have a diagnosis MINOCA. Any patient who does not have a clear cause of troponin rise\n\nExclusion Criteria:\n\n* Patients \\\u003C16 years will not be included in this study.","16 Years",{"count":92,"type":22},3000,"5 Years","The last 15 years the introduction of primary angioplasty has radically improved outcomes for acute myocardial infarction (AMI). However, the system wide availability of prompt investigation has revealed an important group of patients where progress has stalled, the diagnosis is unclear and therapeutic approaches are uncertain. Myocardial infarction with non-obstructive coronary arteries (MINOCA) is found in 1 - 13% of all patients with a clinical diagnosis of AMI.\n\nThese patients present a therapeutic predicament since coronary revascularization is not appropriate. Guidelines do not exist for their management - yet the condition is not benign - the 12-month prognosis, although better than obstructive coronary artery disease patients is still guarded with recent data suggesting many questions remain unanswered.",[96,28,97],"Myocardial Infarction","Coronary Microvascular Disease","2025-11-17",{"date":100,"type":42},"2025-11-18",{"date":102,"type":42},"2020-07-01",{"date":104,"type":22},"2026-09-16",{"name":106,"class":49},"Queen Mary University of London",{"id":108,"slug":109,"hasResults":11,"nctId":110,"briefTitle":111,"officialTitle":111,"acronym":4,"eligibilityCriteria":112,"healthyVolunteers":113,"sex":58,"minAge":18,"maxAge":114,"enrollmentInfo":115,"targetDuration":4,"studyType":61,"phases":117,"briefSummary":118,"conditions":119,"keywords":4,"overallStatus":124,"whyStopped":4,"lastUpdateSubmitDate":125,"lastUpdatePostDateStruct":126,"startDateStruct":128,"completionDateStruct":130,"leadSponsor":132,"locationsCount":82},"100603648","impact-of-gender-difference-and-exercise-intensities-on-depression-and-anxiety-symptoms-among-university-students-100603648","NCT07139249","Impact of Gender Difference and Exercise Intensities on Depression and Anxiety Symptoms Among University Students","Inclusion Criteria:\n\n* Being a student in higher education\n* Being single\n* Age between 18 and 25 years of both sexes\n* Accepting the principle of randomization in the trial.\n* The body mass index is 18.5-24.9 kg\u002Fm².\n* Diagnosed by psychiatrist as having a mild to moderate degree of anxiety and depression.\n* Having scores of 7-24 on the Hamilton Rating Scale for Depression.\n* Having scores of 17-30 on the Hamilton Anxiety Rating Scale.\n\nExclusion Criteria:\n\n* Neurological history such as illness or head trauma\n* Present severe and unstable respiratory disease\n* History of heart defect or cardiovascular disease or any other medical conditions prohibiting high-intensity sport or physical activity\n* Being professional athlete.\n* Involved in regular routine of exercises\n* Taking medication for mental health history of any neurological disorders like neuropathy or seizures.",true,"25 Years",{"count":116,"type":22},84,[63],"This study was done to investigate the impact of gender differences and exercise intensities on depression and anxiety symptoms among university students",[120,121,122,28,123],"Depression","Anxiety","University Students","Exercise Intensity","NOT_YET_RECRUITING","2025-08-17",{"date":127,"type":42},"2025-08-24",{"date":129,"type":22},"2025-08-20",{"date":131,"type":22},"2026-02-01",{"name":133,"class":49},"Cairo University",{"id":135,"slug":136,"hasResults":11,"nctId":137,"briefTitle":138,"officialTitle":138,"acronym":139,"eligibilityCriteria":140,"healthyVolunteers":11,"sex":58,"minAge":18,"maxAge":4,"enrollmentInfo":141,"targetDuration":4,"studyType":24,"phases":4,"briefSummary":143,"conditions":144,"keywords":147,"overallStatus":38,"whyStopped":4,"lastUpdateSubmitDate":151,"lastUpdatePostDateStruct":152,"startDateStruct":154,"completionDateStruct":156,"leadSponsor":158,"locationsCount":82},"100484871","gender-differences-and-age-related-differences-in-emergency-department-admission-100484871","NCT05593692","Gender Differences and Age Related Differences in Emergency Department Admission","SADE","Inclusion Criteria:\n\n* Age over 18 y\n* Admitted to emergency department\n\nExclusion Criteria:\n\n* Age under 18 y",{"count":142,"type":22},15000,"The goal of this observational study is to learn about difference related to age and gender in patients admitted to emergency department.",[145,28,146],"Emergencies","Age Problem",[148,72,149,150],"sex","age","emergency department","2025-03-03",{"date":153,"type":42},"2025-03-05",{"date":155,"type":42},"2022-10-18",{"date":157,"type":22},"2025-10-28",{"name":159,"class":49},"Fondazione Policlinico Universitario Agostino Gemelli IRCCS",{"id":161,"slug":162,"hasResults":11,"nctId":163,"briefTitle":164,"officialTitle":165,"acronym":166,"eligibilityCriteria":167,"healthyVolunteers":11,"sex":58,"minAge":18,"maxAge":4,"enrollmentInfo":168,"targetDuration":4,"studyType":24,"phases":4,"briefSummary":170,"conditions":171,"keywords":4,"overallStatus":38,"whyStopped":4,"lastUpdateSubmitDate":173,"lastUpdatePostDateStruct":174,"startDateStruct":176,"completionDateStruct":178,"leadSponsor":180,"locationsCount":82},"100499931","gender-based-impact-on-safety-and-efficacy-of-lenvatinib-in-patients-with-differentiated-thyroid-cancer-100499931","NCT05789667","Gender-based Impact on Safety and Efficacy of Lenvatinib in Patients With Differentiated Thyroid Cancer","Observational Study on Gender-based Impact on Safety and Efficacy of Lenvatinib in Patients With Radioiodine Refractory Differentiated Thyroid Cancer","Gisel","Inclusion Criteria:\n\n* Patients with refractory iodine DTC treated with lenvatinib\n* Signed written informed consent\n\nExclusion Criteria:\n\n\\- Age \\\u003C 18 years",{"count":169,"type":22},50,"Lenvatinib is approved for the treatment of radioiodine refractory differentiated thyroid cancer. Despite gender can play a crucial role un in safety and efficacy of oncological product, little is know on gender difference in lenvatinb effacacy and safety in the context of radioiodine refractory differentiated thyroid cancer.\n\nThe primary objective of the study is to assess safety and toxicity profile in male and female patients in terms of dose reduction. The secondary objectives are to assess sex and gender difference in: the number and the incidence of adverse events; response rate according to RECIST criteria 1.1; progression free survival, overall survival and duration of response.",[172,28],"Differentiated Thyroid Cancer","2024-12-05",{"date":175,"type":42},"2024-12-06",{"date":177,"type":42},"2020-05-27",{"date":179,"type":22},"2025-12-31",{"name":181,"class":49},"Regina Elena Cancer Institute",{"id":183,"slug":184,"hasResults":11,"nctId":185,"briefTitle":186,"officialTitle":187,"acronym":4,"eligibilityCriteria":188,"healthyVolunteers":113,"sex":189,"minAge":4,"maxAge":4,"enrollmentInfo":190,"targetDuration":4,"studyType":61,"phases":192,"briefSummary":193,"conditions":194,"keywords":197,"overallStatus":124,"whyStopped":4,"lastUpdateSubmitDate":203,"lastUpdatePostDateStruct":204,"startDateStruct":206,"completionDateStruct":208,"leadSponsor":210,"locationsCount":4},"100556019","building-your-successful-nursing-career-100556019","NCT06519643","Building Your Successful Nursing Career","Building Your Successful Nursing Career: Evaluating the Effectiveness of a Career Planning Mobile Application for Male Nurses - a Randomized Double-blind Controlled Trial","Inclusion Criteria:\n\n1. Male nursing staff currently engaged in clinical nursing work.\n2. Care Within 15 years of working experience.\n3. Have a mobile phone with Internet access.\n4. Have clear consciousness and can understand and answer the researcher's questions.\n5. Audible and understandable Or understand Chinese.\n6. Willing to participate in this study and sign the subject consent form.\n\nExclusion Criteria:\n\n1. Unwilling to participate in this study.\n2. Those who cannot download the App.","MALE",{"count":191,"type":22},120,[63],"This study aims to evaluate a career planning mobile App specifically tailored for male nurses.This three-year experimental project aims to recruit 120 male nurses (60）in the experimental group and 60 in the control group). Employing a prospective double-blind randomized controlled trial (RCT) design, the study will include six follow-up points (pre-intervention, post-intervention at 0, 6, 12, 18, and 24 months) to examine the effectiveness of career self-efficacy, career adaptive behaviors, occupational resilience, career success, and career continuity intentions of male nurses over time. The repeated measures data will be analyzed with the intention-to-treat analysis method and General Estimating Equations (GEE). This research represents an innovative development of the world's first theoretically grounded career planning mobile App for male nurses.The study's results can serve as a valuable reference for future career planning initiatives in nursing practice and education.",[195,28,196],"Nurse's Role","Professional Burnout",[198,199,200,201,202],"male nurse","career plan","mobile application (App)","intervention study","randomized controlled trial","2024-07-19",{"date":205,"type":42},"2024-07-25",{"date":207,"type":22},"2024-08-01",{"date":209,"type":22},"2027-08-05",{"name":211,"class":49},"Chang Gung Memorial Hospital"]