[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"general-anesthetic-drug-adverse-reaction\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:general-anesthetic-drug-adverse-reaction":25},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,4,0,[8,40,76,103],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":13,"acronym":4,"eligibilityCriteria":14,"healthyVolunteers":11,"sex":15,"minAge":16,"maxAge":4,"enrollmentInfo":17,"targetDuration":4,"studyType":20,"phases":4,"briefSummary":21,"conditions":22,"keywords":4,"overallStatus":27,"whyStopped":4,"lastUpdateSubmitDate":28,"lastUpdatePostDateStruct":29,"startDateStruct":32,"completionDateStruct":34,"leadSponsor":36,"locationsCount":39},"100578650","carotid-artery-corrected-flow-time-and-inferior-vena-cava-collapsibility-index-for-prediction-of-hypotension-after-induction-of-general-anesthesia-in-geriatric-patients-undergoing-elective-surgery-100578650",false,"NCT06814054","Carotid Artery Corrected Flow Time and Inferior Vena Cava Collapsibility Index for Prediction of Hypotension After Induction of General Anesthesia in Geriatric Patients Undergoing Elective Surgery","Inclusion Criteria:\n\n* American Society of Anaesthesiologists Physical Status I to Ⅱ\n* receiving general anesthesia for elective surgery\n* fasted for at least 6 to 8 hours were recruited in this study\n\nExclusion Criteria:\n\n* • patients who refused to participate in the study\n\n  * American Society of Anaesthesiologists Physical Status Ⅲ or Ⅳ\n  * Patients with a history of peripheral arterial diseases or atherosclerosis\n  * Patients with body mass index of greater than 30 kg\u002Fm2\n  * Patients with arrhythmia or cardiomyopathy\n  * Chronic obstructive pulmonary disease (COPD)\n  * baseline systolic arterial pressure (SAP) ≥ 180 mmHg or \\\u003C 90mmHg\n  * Any episode of desaturation or difficult intubation during general anasethia induction","ALL","65 Years",{"count":18,"type":19},189,"ESTIMATED","OBSERVATIONAL","In this observational study, we will assess cFT by Carotid ultrasound and IVC collapsibility index for prediction of hypotension after induction of general anesthesia in geriatric patients undergoing elective surgery.",[23,24,25,26],"Geriatrics","Hypotension on Induction","General Anesthetic Drug Adverse Reaction","Elective Surgery","RECRUITING","2025-06-29",{"date":30,"type":31},"2025-07-01","ACTUAL",{"date":33,"type":31},"2025-03-01",{"date":35,"type":19},"2026-05",{"name":37,"class":38},"Tanta University","OTHER",1,{"id":41,"slug":42,"hasResults":11,"nctId":43,"briefTitle":44,"officialTitle":45,"acronym":46,"eligibilityCriteria":47,"healthyVolunteers":11,"sex":48,"minAge":49,"maxAge":4,"enrollmentInfo":50,"targetDuration":4,"studyType":52,"phases":53,"briefSummary":55,"conditions":56,"keywords":61,"overallStatus":27,"whyStopped":4,"lastUpdateSubmitDate":67,"lastUpdatePostDateStruct":68,"startDateStruct":70,"completionDateStruct":72,"leadSponsor":74,"locationsCount":39},"100532684","incidence-of-residual-neuromuscular-blockade-in-fraility-in-oncogynae-surgery-100532684","NCT06216002","Incidence of Residual Neuromuscular Blockade in Fraility in OncoGynae Surgery","Incidence of Residual Neuromuscular Blockade in Patients With Frailty Undergoing Gynecologic Cancer Surgery","FIGO","Inclusion Criteria:\n\n* Age \\>,= 18 years\n* Patients undergoing elective gynecologic-oncology surgery\n\nExclusion Criteria:\n\n* Unable to communicate Thai\n* Unable to understand the questionnaire\n* Preexisting neuromuscular disease\n* Preexisting disease involved wrist that may affect the nerve stimulator examination","FEMALE","18 Years",{"count":51,"type":19},622,"INTERVENTIONAL",[54],"NA","Frailty among patients undergoing surgery is strongly associated with an elevated risk of adverse perioperative outcomes, heightened incidence of postoperative complications, increased mortality rates, and prolonged hospital length of stay. Our focus centers on investigating the frailty index in the context of complications experienced by patients undergoing oncologic gynecology surgery. The principal objective of this research is to elucidate the extent to which residual neuromuscular blocking agents are linked to frailty.",[57,58,25,59,60],"Frailty","Neuromuscular Blockade","Gynecologic Cancer","Surgical Complication",[62,63,64,65,66],"neuromuscular blocking agents","frailty","gynecologic oncology","surgery","anesthetic complications","2025-05-07",{"date":69,"type":31},"2025-05-08",{"date":71,"type":31},"2024-01-02",{"date":73,"type":19},"2025-12-31",{"name":75,"class":38},"Mahidol University",{"id":77,"slug":78,"hasResults":11,"nctId":79,"briefTitle":80,"officialTitle":81,"acronym":82,"eligibilityCriteria":83,"healthyVolunteers":11,"sex":15,"minAge":84,"maxAge":85,"enrollmentInfo":86,"targetDuration":4,"studyType":20,"phases":4,"briefSummary":88,"conditions":89,"keywords":90,"overallStatus":92,"whyStopped":4,"lastUpdateSubmitDate":93,"lastUpdatePostDateStruct":94,"startDateStruct":96,"completionDateStruct":98,"leadSponsor":100,"locationsCount":102},"100555668","predicting-outcomes-using-infra-red-sensors-a-feasibility-study-100555668","NCT06515080","Predicting Outcomes Using Infra-red SEnsors, a Feasibility Study.","Physiological Monitoring in the OR; Predicting Outcomes Using Infra-red SEnsors, a Feasibility Study.","PORPOISE-F","Inclusion Criteria:\n\n* Children scheduled for both elective and non-elective, non-cardiac surgical procedures under general anaesthesia.\n\nExclusion Criteria:\n\n* age \\< 6 months or ≥ 59 months\n\n  * procedures requiring \\< 30 minutes of general anaesthesia\n  * imaging procedures\n  * procedures involving neurosurgery, oncology or burns\n  * procedures involving significant pain lasting for more than 1 week on average (e.g. tonsillectomies, major orthopaedic surgery)\n  * other procedures that limit access to the forehead\n  * children that are on supplemental oxygen, are sedated or intubated at the time of inclusion\n  * children with severe developmental delay\n  * procedures with planned postoperative intensive care or hospital stay \\> 3 days","6 Months","59 Months",{"count":87,"type":19},500,"The aim of this study is to investigate if it is feasible to use a protocol in which avoiding oxygen desaturation in the brain during general anaesthesia can reduce the risk of negative postoperative behavior changes in children.\n\nWe will recruit children from at least five centres around the world for this feasibility study. Brain oxygenation will be monitored with Near Red Infrascopy (NIRS) which is like a saturation monitor placed on the forehead of the child during anesthesia. The anesthesia is done as per routine, but we will ask the anesthesiologist to record what actions they took when there were signs of decreasing oxygen saturation in the brain. We will also ask the parents to fill in a questionnaire with 27 questions about changes in their child's behavior 7 days after the operation.",[25],[91],"regional oxygen saturation","NOT_YET_RECRUITING","2025-02-20",{"date":95,"type":31},"2025-02-24",{"date":97,"type":19},"2025-03-31",{"date":99,"type":19},"2026-07-31",{"name":101,"class":38},"Uppsala University",5,{"id":104,"slug":105,"hasResults":11,"nctId":106,"briefTitle":107,"officialTitle":108,"acronym":4,"eligibilityCriteria":109,"healthyVolunteers":11,"sex":15,"minAge":49,"maxAge":110,"enrollmentInfo":111,"targetDuration":4,"studyType":52,"phases":113,"briefSummary":114,"conditions":115,"keywords":122,"overallStatus":27,"whyStopped":4,"lastUpdateSubmitDate":130,"lastUpdatePostDateStruct":131,"startDateStruct":133,"completionDateStruct":135,"leadSponsor":137,"locationsCount":39},"100570460","the-potential-protective-effect-of-using-muscle-relaxants-during-electroporation-ablation-pfa-100570460","NCT06707532","The Potential Protective Effect of Using Muscle Relaxants During Electroporation Ablation (PFA)","The Use of Muscle Relaxants During Electroporation Ablation (PFA) as a Potential Protective Factor Against Damage to Transverse Striated Muscle Tissue and the Heart","Inclusion Criteria:\n\n* Patients with requirement for PFA ablation for cardiac indications and ability to provide informed consent for study participation\n\nExclusion Criteria:\n\n* Patients with allergies to the general anaesthetics used, genetic diseases of the neuromuscular plateau - e.g. Duchenne dystrophy, myasthenia gravis - and patients who do not gived informed consent to participate in the study will be excluded from the study.","90 Years",{"count":112,"type":19},32,[54],"The study aims to improve the safety of the electroporation ablation (PFA) procedure by using muscle relaxants to reduce skeletal muscle damage during the procedure. It will also assess myocardial damage to improve the procedure's quality and speed up recovery after the procedure.",[116,117,118,119,120,25,121],"Kidney Failure, Acute","Myopathy; Drugs","Heart Arrhythmia","Succinylcholine Sensitivity","Muscle Relaxation","Projection",[123,124,125,126,127,128,129],"electroporation ablation (PFA)","muscle relaxants","rocuronium","chronic pain","acute kidney failure","chronic heart failure","drug protection","2024-11-26",{"date":132,"type":31},"2024-11-27",{"date":134,"type":31},"2024-08-01",{"date":136,"type":19},"2025-12-01",{"name":138,"class":38},"4th Military Clinical Hospital with Polyclinic, Poland"]