[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"genicular-nerves\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:genicular-nerves":26},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,2,0,[8,41],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":13,"acronym":4,"eligibilityCriteria":14,"healthyVolunteers":11,"sex":15,"minAge":16,"maxAge":4,"enrollmentInfo":17,"targetDuration":4,"studyType":20,"phases":21,"briefSummary":23,"conditions":24,"keywords":4,"overallStatus":28,"whyStopped":4,"lastUpdateSubmitDate":29,"lastUpdatePostDateStruct":30,"startDateStruct":33,"completionDateStruct":35,"leadSponsor":37,"locationsCount":40},"100516466","peripheral-nerve-stimulation-of-genicular-nerves-versus-conventional-therapy-with-intra-articular-steroid-injection-for-chronic-knee-pain-a-prospective-randomized-pilot-study-100516466",false,"NCT06004882","Peripheral Nerve Stimulation of Genicular Nerves Versus Conventional Therapy With Intra-articular Steroid Injection for Chronic Knee Pain: A Prospective, Randomized Pilot Study","Inclusion Criteria:\n\n* Patients diagnosed with chronic knee pain (baseline pain score \\>=4), seen at Pain Management Center at MD Anderson Cancer Center; if patient has bilateral knee pain, the side with the more severe knee pain will be treated first and counted towards the primary and secondary endpoints\n* Patients between ages 18-85 years old\n* Patient signed informed consent\n\nExclusion Criteria:\n\n* Patients with cognitive dysfunction or without capacity to consent\n* Patient with recent history (\\\u003C6 months) of drug or alcohol abuse\n* Patients with open skin lesion or undergoing antibiotic therapy for local for systemic infection\n* Patients with allergies to local anesthesia, steroids, or adhesives\n* Patients who are on opioids for reasons other than knee pain","ALL","18 Years",{"count":18,"type":19},45,"ESTIMATED","INTERVENTIONAL",[22],"NA","To compare the effects of the following types of therapy on knee range of motion when given to patients with chronic knee pain:\n\n* A standard steroid injection\n* Peripheral nerve stimulation (PNS) therapy in combination with a standard steroid injection\n* PNS therapy in combination with a placebo injection\n\nSteroid injections are given directly into the knee joints and are considered to be the standard therapy for chronic knee pain. In this study, the injection will be made of the steroid drugs triamcinolone and bupivacaine.",[25,26,27],"Peripheral Nerve Stimulation","Genicular Nerves","Chronic Knee Pain","RECRUITING","2026-02-27",{"date":31,"type":32},"2026-03-03","ACTUAL",{"date":34,"type":32},"2023-08-10",{"date":36,"type":19},"2027-01-31",{"name":38,"class":39},"M.D. Anderson Cancer Center","OTHER",1,{"id":42,"slug":43,"hasResults":11,"nctId":44,"briefTitle":45,"officialTitle":46,"acronym":47,"eligibilityCriteria":48,"healthyVolunteers":11,"sex":15,"minAge":16,"maxAge":4,"enrollmentInfo":49,"targetDuration":4,"studyType":20,"phases":51,"briefSummary":52,"conditions":53,"keywords":59,"overallStatus":28,"whyStopped":4,"lastUpdateSubmitDate":64,"lastUpdatePostDateStruct":65,"startDateStruct":67,"completionDateStruct":69,"leadSponsor":71,"locationsCount":40},"100625655","cryoneurolysis-prior-to-total-knee-arthroplasty-cryo-tka-trial-100625655","NCT07425457","Cryoneurolysis Prior to Total Knee Arthroplasty (CRYO-TKA Trial)","Association of Pre-operative Genicular Nerves Cryoneurolysis With Improved Pain and Function in Patients Undergoing Total Knee Arthroplasty","CRYO-TKA","Inclusion Criteria:\n\n* Adults ≥18 years undergoing primary TKA for osteoarthritis.\n* Cognitively normal and able to self-assess pain and function.\n* Provide written informed consent.\n\nExclusion Criteria:\n\n* Cancer-related knee pain.\n* Neurological, psychiatric, or medical conditions interfering with assessment.\n* Chronic opioid users.",{"count":50,"type":19},100,[22],"Approximately 20-30% of patients experience persistent pain after a Total Knee Arthroplasty (TKA). This study investigates whether percutaneous cryoneurolysis of genicular nerves can reduce pain and improve physical function when performed at least 24 hours before surgery. Participants will be randomized to receive either the cryoneurolysis procedure + TKA or TKA only. Results will be tracked for 6 months to see if the intervention improves long-term recovery and quality of life.",[54,55,56,57,26,58],"Arthroplasty","Replacement Material","Knee Arthritis Osteoarthritis","Knee Arthroplasty, Total","Chronic Pain",[60,61,62,63],"Cryoneurolysis","Interventional Radiology","Pain Management","Post-operative recovery","2026-02-19",{"date":66,"type":32},"2026-02-20",{"date":68,"type":32},"2026-01-02",{"date":70,"type":19},"2028-03-31",{"name":72,"class":39},"Attikon Hospital"]