[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"genu-varum\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:genu-varum":26},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,7,0,[8,39,65,96,128,149,172],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":4,"eligibilityCriteria":15,"healthyVolunteers":11,"sex":16,"minAge":4,"maxAge":4,"enrollmentInfo":17,"targetDuration":4,"studyType":20,"phases":21,"briefSummary":23,"conditions":24,"keywords":4,"overallStatus":27,"whyStopped":4,"lastUpdateSubmitDate":28,"lastUpdatePostDateStruct":29,"startDateStruct":32,"completionDateStruct":34,"leadSponsor":36,"locationsCount":4},"100635315","kinematic-vs-mechanical-alignment-in-high-tibial-osteotomy-100635315",false,"NCT07551089","Kinematic vs Mechanical Alignment in High Tibial Osteotomy","The Short Term Outcome of Kinematic Versus Mechanichal Alignment After High Tibial Osteotomy for Varus Osteoarthritic Knee : A Prospective Randomized Controlled Trial","Inclusion Criteria:\n\n* Clinical: 1. Age : Adult with symptomatic osteoarthritic varus knee 2-Medial knee pain with functional limitation ≥6 months despite optimized non-operative care.\n\nRadiological: 1- Medial compartment OA in Xray AP-Lateral view 2-Degree of varus ≥3 and ≤15 degree in long film(full-length, standing hip-to-ankle radiographs) 3-•Varus knee (mpta ≤85 degree and ldfa ≤93 and jlca ≤5)\n\nPhysical : 1-Range of motion: Flexion ≥110°, flexion contracture ≤10°, extension lag ≤5°.\n\n2-Gait testing: Able to walk unaided (or with standard aid) for instrumented gait analysis.\n\nExclusion Criteria:\n\n* 1- Predominantly lateral compartment OA 2- severe patellofemoral arthritis 3- Prior high tibial osteotomy, knee arthroplasty, or complex fracture around the knee 4-Inflammatory arthropathies (eg, rheumatoid arthritis) 5- end stage medial compartment osteoarthritis with bone erosions 6-chondrocalcinosis","ALL",{"count":18,"type":19},100,"ESTIMATED","INTERVENTIONAL",[22],"NA","To compare between kinematic and mechanichal alignment after High Tibial Osteotomy (clinically and radiologically)",[25,26],"Osteo Arthritis of the Knee","Genu Varum","NOT_YET_RECRUITING","2026-05-21",{"date":30,"type":31},"2026-05-26","ACTUAL",{"date":33,"type":19},"2026-06-01",{"date":35,"type":19},"2029-10-01",{"name":37,"class":38},"Assiut University","OTHER",{"id":40,"slug":41,"hasResults":11,"nctId":42,"briefTitle":43,"officialTitle":44,"acronym":4,"eligibilityCriteria":45,"healthyVolunteers":11,"sex":16,"minAge":46,"maxAge":4,"enrollmentInfo":47,"targetDuration":4,"studyType":20,"phases":49,"briefSummary":50,"conditions":51,"keywords":4,"overallStatus":27,"whyStopped":4,"lastUpdateSubmitDate":55,"lastUpdatePostDateStruct":56,"startDateStruct":58,"completionDateStruct":60,"leadSponsor":62,"locationsCount":64},"100609888","to-plate-fixation-vs-external-fixator-comparison-hto-plate-vs-exfix-study-100609888","NCT07220434","TO Plate Fixation vs. External Fixator Comparison (HTO Plate vs. ExFix Study)","Medial Opening Wedge High Tibial Osteotomy: A Comparative Study of Plate Fixation and Self-Adjusting HTO External Fixator Techniques","Inclusion Criteria:\n\n* Varus malalignment associated with medial compartment degeneration\u002Fosteoarthritis.\n\nIndication for Medial Opening Wedge HTO. Aged 18 years or older. Willing to participate in the study and provide written informed consent.\n\nExclusion Criteria:\n\n* Advanced-stage osteoarthritis (Indication for Total Knee Arthroplasty). Previous open knee surgery on the same extremity. Inability to comply with follow-up appointments. Significant comorbidities (e.g., uncontrolled diabetes, rheumatoid arthritis).","18 Years",{"count":48,"type":19},28,[22],"This study aims to compare the efficacy, accuracy, and functional outcomes of two different surgical stabilization techniques for medial opening wedge high tibial osteotomy (HTO) in patients with varus deformity and medial compartment osteoarthritis. Patients will be prospectively randomized into two groups: Group 1 (Plate Fixation) will receive acute (single-stage) correction and stabilization with a medial HTO locking plate. Group 2 (HTO External Fixator) will receive stabilization using a self-adjusting HTO external fixator, followed by gradual correction (hemicallotasis\u002Fdistraction) starting 7 days post-operatively. The study will evaluate radiological correction, functional improvement (using the Oxford Knee Score), and complication rates over a 12-month follow-up period.",[52,26,53,54],"Medial Compartment Osteoarthritis","Varus Deformity","High Tibial Osteotomy","2025-10-22",{"date":57,"type":31},"2025-10-23",{"date":59,"type":19},"2025-11-15",{"date":61,"type":19},"2028-12-31",{"name":63,"class":38},"Muhammed Cagatay Engin",1,{"id":66,"slug":67,"hasResults":11,"nctId":68,"briefTitle":69,"officialTitle":70,"acronym":71,"eligibilityCriteria":72,"healthyVolunteers":11,"sex":16,"minAge":73,"maxAge":74,"enrollmentInfo":75,"targetDuration":4,"studyType":20,"phases":77,"briefSummary":78,"conditions":79,"keywords":80,"overallStatus":27,"whyStopped":4,"lastUpdateSubmitDate":87,"lastUpdatePostDateStruct":88,"startDateStruct":90,"completionDateStruct":92,"leadSponsor":94,"locationsCount":64},"100603767","effects-of-hip-blood-flow-restriction-and-shockwave-therapy-on-q-angle-and-plantar-pressure-in-adults-with-genu-varum-100603767","NCT07140796","Effects of Hip Blood Flow Restriction and Shockwave Therapy on Q-Angle and Plantar Pressure in Adults With Genu Varum","\"A Crossover Study Investigating the Effects of Gluteus Medius-Focused Blood Flow Restriction Training With or Without Radial Shockwave Therapy on Q-Angle and Plantar Pressure in Adults With Genu Varum\"","BFR-GVQ","Inclusion Criteria:\n\n* Adults aged between 20 and 40 years\n* Diagnosed with genu varum (inter-knee distance ≥ 3 cm in standing position)\n* No pain or surgery history in lower extremities within the last 6 months\n* Able to walk independently without assistance\n* Provide written informed consent\n\nExclusion Criteria:\n\n* Neurological or musculoskeletal disorders affecting gait or posture\n* Current use of medication affecting musculoskeletal or circulatory function\n* Previous surgery on the spine, pelvis, or lower limbs\n* Contraindications to shockwave therapy or BFR training (e.g., thromboembolic - disorders, deep vein thrombosis, cancer, etc.)\n* Participation in other clinical trials within the past month","20 Years","40 Years",{"count":76,"type":19},14,[22],"This study aims to investigate the effects of gluteus medius-focused blood flow restriction (BFR) training, with or without the addition of radial shockwave therapy, on lower limb alignment in adults with genu varum. The study uses a crossover design and evaluates changes in Q-angle(Quadriceps-angle) and plantar pressure as primary outcomes. All interventions are non-invasive and supervised, and the goal is to identify effective therapeutic strategies to improve biomechanical alignment in individuals with bowed legs.",[26],[81,82,83,84,85,86],"Genu varum","Blood Flow Restriction","BFR Training","Radial Shockwave Therapy","Q-angle","Plantar pressure","2025-08-25",{"date":89,"type":31},"2025-09-02",{"date":91,"type":19},"2025-09-10",{"date":93,"type":19},"2026-01-01",{"name":95,"class":38},"Sungjin Park",{"id":97,"slug":98,"hasResults":11,"nctId":99,"briefTitle":100,"officialTitle":101,"acronym":102,"eligibilityCriteria":103,"healthyVolunteers":11,"sex":16,"minAge":104,"maxAge":105,"enrollmentInfo":106,"targetDuration":4,"studyType":20,"phases":108,"briefSummary":109,"conditions":110,"keywords":115,"overallStatus":27,"whyStopped":4,"lastUpdateSubmitDate":120,"lastUpdatePostDateStruct":121,"startDateStruct":123,"completionDateStruct":125,"leadSponsor":127,"locationsCount":64},"100583645","plate-vs-screw-for-guided-growth-in-coronal-knee-deformities-100583645","NCT06879015","Plate vs. Screw for Guided Growth in Coronal Knee Deformities","Tension Band Plate (TBP) vs Percutaneous Epiphysiodesis by Transphyseal Screw (PETS) in Coronal Angular Knee Deformities in Children: a Randomized Controlled Study","PETS vs TBP","Inclusion Criteria:\n\n1. Children and adolescents beyond the age of physiological varus\u002Fvalgus correction (i.e., typically ≥4 years for genu varum and ≥7 years for genu valgum) with Mechanical Axis Deviation (MAD) in lower limbs and abnormal joint orientation angles, in the coronal plane either femoral or tibial.\n2. Open physis (growth plate) on radiographs and at least one year of growth remaining before age of skeletal maturity (typically ≤14 years in females, ≤16 years in males).\n\nExclusion Criteria:\n\n1. Sick Physis as in Blount's disease stages III-V or any partial or total physeal arrest caused by trauma, inflammation or neoplasia.\n2. Uncorrectable systemic disorders affecting bone growth and alignment, including but not limited to:\n\n   i- Severe metabolic disorders (e.g., advanced rickets, hypophosphatasia, mucopolysaccharidoses) ii- Uncontrolled endocrine disorders (e.g., untreated hypothyroidism, growth hormone abnormalities) iii- Severe connective tissue disorders (e.g., osteogenesis imperfecta, advanced Ehlers-Danlos syndrome) iv- Chronic inflammatory or hematologic conditions that impair bone growth (e.g., severe juvenile idiopathic arthritis, advanced sickle cell disease)","7 Years","16 Years",{"count":107,"type":19},60,[22],"The goal of this clinical trial is to compare two surgical techniques, Tension Band Plate (TBP) and Percutaneous Epiphysiodesis by Transphyseal Screw (PETS), in children with coronal angular knee deformities.\n\nThe main questions it aims to answer are:\n\n* Which technique provides better correction of coronal knee deformities?\n* Are there differences in complication rates or recovery times between TBP and PETS?\n\nParticipants will:\n\n* Undergo either TBP or PETS surgery for knee deformity correction.\n* Attend follow-up visits for radiographic and clinical evaluations.\n\nResearchers will compare TBP and PETS groups to see if one method leads to better deformity correction and fewer complications.",[111,112,113,26,114],"Epiphysiodesis","Bone Malalignment","Lower Extremity Deformities, Congenital","Genu Valgum",[116,117,118,119],"Guided Growth","Growth Modulation","Tension Band Plate","Percutaneous Epiphysiodesis by Transphyseal Screw","2025-03-14",{"date":122,"type":31},"2025-03-17",{"date":124,"type":19},"2025-04-01",{"date":126,"type":19},"2027-06-01",{"name":37,"class":38},{"id":129,"slug":130,"hasResults":11,"nctId":131,"briefTitle":132,"officialTitle":132,"acronym":4,"eligibilityCriteria":133,"healthyVolunteers":11,"sex":16,"minAge":73,"maxAge":134,"enrollmentInfo":135,"targetDuration":4,"studyType":20,"phases":136,"briefSummary":137,"conditions":138,"keywords":4,"overallStatus":139,"whyStopped":4,"lastUpdateSubmitDate":140,"lastUpdatePostDateStruct":141,"startDateStruct":143,"completionDateStruct":145,"leadSponsor":147,"locationsCount":64},"100564704","effect-of-lateral-wedged-insoles-with-subtalar-strapping-on-genu-varum-with-medial-compartment-knee-pain-100564704","NCT06632639","Effect of Lateral Wedged Insoles With Subtalar Strapping on Genu Varum With Medial Compartment Knee Pain","Inclusion Criteria:\n\n* Patients of both genders aged 20-60.\n* Patients with medial compartment pain. Pain level of 3 or more on the VAS.\n* Patients with varus deformity are defined as those Those whose femorotibial angle measures 5-10 degrees of genu varum on long film weight bearing x-ray.\n* Patients with grade one O.A. on Kellgren-Lawrence classification system or without O.A.\n* BMI less than 35\n* Patients with decompensated hind foot (hind foot varus)\n\nExclusion Criteria:\n\n* Patients already wearing custom wedged insoles.\n* Patients with other inflammatory conditions like rheumatoid arthritis or systematic inflammatory arthritis.\n* Patients with central or peripheral nervous system disease.\n* Any previous surgical procedure to the knee joint.\n* Patients who are unable to walk without assistance (cane or a walker).\n* Pregnancy\n* Uncooperative patient types due to mental disorders or others.","60 Years",{"count":107,"type":19},[22],"The purpose of the study is to investigate the effect of lateral wedged insoles with subtalar strapping in genu varum with medial compartment knee pain on:\n\n1. Space between knees (measured by vernier calipers)\n2. Degree of genu varum deformity (Femorotibial angle (FTA)) measured on long film weight bearing x-ray)\n3. Pain level (Measured by VAS)\n4. Hind foot angle (measured by long axial hindfoot alignment view)\n5. Functional outcome (measured by the lower extremity function scale)\n6. Functional performance (measured by the 6 minute walk test)",[26],"RECRUITING","2024-11-22",{"date":142,"type":31},"2024-11-26",{"date":144,"type":31},"2024-11-12",{"date":146,"type":19},"2025-10-31",{"name":148,"class":38},"Cairo University",{"id":150,"slug":151,"hasResults":11,"nctId":152,"briefTitle":153,"officialTitle":154,"acronym":4,"eligibilityCriteria":155,"healthyVolunteers":156,"sex":16,"minAge":157,"maxAge":46,"enrollmentInfo":158,"targetDuration":4,"studyType":20,"phases":160,"briefSummary":161,"conditions":162,"keywords":4,"overallStatus":139,"whyStopped":4,"lastUpdateSubmitDate":163,"lastUpdatePostDateStruct":164,"startDateStruct":166,"completionDateStruct":168,"leadSponsor":170,"locationsCount":64},"100564576","hemiepiphysiodesis-by-eight-plate-versus-osteotomy-in-the-management-of-pediatric-coronal-knee-deformities-100564576","NCT06630975","Hemiepiphysiodesis by Eight Plate Versus Osteotomy in the Management of Pediatric Coronal Knee Deformities","Resident at AlAzhar University Assuit","Inclusion Criteria:\n\n* Growth plate still open at Time of Surgery\n\nExclusion Criteria:\n\n* Epiphyseal plate involved in trauma resulting in a bridging callus formation,",true,"2 Years",{"count":159,"type":19},2,[22],"Coronal angular deformities of lower limb in children are a common finding in pediatric orthopedic surgery.These angular deformities can be idiopathic in origin, or they can emerge secondary to congenital and acquired abnormalities. Persistent coronal plane deformities around knee (genu varum\u002Fvalgum) could lead to meniscal tears, collateral ligament laxity, cartilage degeneration, and early osteoarthritis due to gradual mechanical axis disruption",[26],"2024-10-05",{"date":165,"type":31},"2024-10-08",{"date":167,"type":31},"2024-09-25",{"date":169,"type":19},"2025-10-01",{"name":171,"class":38},"Al-Azhar University",{"id":173,"slug":174,"hasResults":11,"nctId":175,"briefTitle":176,"officialTitle":177,"acronym":4,"eligibilityCriteria":178,"healthyVolunteers":11,"sex":16,"minAge":179,"maxAge":4,"enrollmentInfo":180,"targetDuration":4,"studyType":182,"phases":4,"briefSummary":183,"conditions":184,"keywords":187,"overallStatus":139,"whyStopped":4,"lastUpdateSubmitDate":192,"lastUpdatePostDateStruct":193,"startDateStruct":195,"completionDateStruct":197,"leadSponsor":199,"locationsCount":64},"100511236","adductor-ratio-in-severe-varus-gonarthrosis-100511236","NCT05936814","Adductor Ratio in Severe Varus Gonarthrosis","The Adductor Ratio is More Reliable Than Other Techniques in Determining Joint Line in Severe Type M Varus Gonarthrosis","Inclusion Criteria:\n\n* Patients over 65 years of age\n* Candidates with varus alignment osteoarthritis of the knee\n* Patients with complete data set\n* Patients who have agreed to participate in the study\n\nExclusion Criteria:\n\n* Patients who did not provide consent to participate in the study\n* Patients with post-traumatic osteoarthritis\n* Patients with inflammatory type of osteoarthritis\n* Patients with incomplete data set","65 Years",{"count":181,"type":19},68,"OBSERVATIONAL","The restoration of the joint line (JL) is essential for the proper functioning of Total Knee Arthroplasty (TKA). The exact position of JL can be determined using anatomical landmarks such as femoral condylar width (TEW), tibial tubercle, fibular head, and adductor tubercle during preoperative planning or intraoperatively. However, in cases of severe varus deformity in Type M gonarthrosis, it is unknown which method is most suitable for accurately determining the precise JL position. The aim of this study is to identify the most appropriate method for determining the JL position in Type M gonarthrosis. To achieve this goal, two groups of patients with Type 1A and Type M gonarthrosis will be compared by measuring preoperative values and comparing them with intraoperative reference values.",[185,26,186],"Osteoarthritis, Knee","Joint Prosthesis; Complications",[188,189,190,191],"Varus deformity","Adductor tubercle","Joint line restoration","Total knee arthroplasty","2023-07-08",{"date":194,"type":31},"2023-07-11",{"date":196,"type":31},"2021-12-01",{"date":198,"type":19},"2027-01-31",{"name":200,"class":38},"Saglik Bilimleri Universitesi"]