[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"geriatric-anesthesia\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:geriatric-anesthesia":28},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,5,0,[8,42,67,88,118],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":4,"eligibilityCriteria":15,"healthyVolunteers":11,"sex":16,"minAge":17,"maxAge":4,"enrollmentInfo":18,"targetDuration":4,"studyType":21,"phases":22,"briefSummary":24,"conditions":25,"keywords":4,"overallStatus":29,"whyStopped":4,"lastUpdateSubmitDate":30,"lastUpdatePostDateStruct":31,"startDateStruct":34,"completionDateStruct":36,"leadSponsor":38,"locationsCount":41},"100640397","binaural-sound-during-phacoemulsification-and-posterior-chamber-lens-implantation-in-geriatric-patients-100640397",false,"NCT07609186","Binaural Sound During Phacoemulsification and Posterior Chamber Lens Implantation in Geriatric Patients","Effect of Binaural Sound During Phacoemulsification and Posterior Chamber Lens Implantation on Postoperative Patient Satisfaction in Geriatric Patients: a Single-blind, Randomized Controlled Trial","Inclusion Criteria:\n\n* Patients scheduled to undergo their first phacoemulsification and posterior chamber intraocular lens implantation (PE \\& PCL) under monitored anesthesia care (MAC).\n* Patients aged 65 years or older.\n* Patients who fully understand the study and voluntarily provide written informed consent to participate.\n\nExclusion Criteria:\n\n* Patients undergoing their second consecutive PE \\& PCL surgery.\n* Patients with hearing loss, hearing impairment, or those who use hearing aids.\n* Patients unable to wear earphones due to diseases of the external auditory canal.\n* Patients who chronically use hypnotics or sedatives.\n* Patients with a history of obstructive sleep apnea or a Body Mass Index of 35 kg\u002Fm² or higher.\n* Patients with a history of alcohol or drug dependence.\n* Patients with a history of epilepsy or seizure disorders.\n* Patients who are unable to complete a written questionnaire.\n* Patients deemed unsuitable for participation in the clinical trial based on the investigator's clinical judgment.","ALL","65 Years",{"count":19,"type":20},60,"ESTIMATED","INTERVENTIONAL",[23],"NA","The purpose of this study is to evaluate the effects of binaural beats on patient satisfaction and intraoperative comfort in patients aged 65 years or older undergoing cataract surgery (phacoemulsification and posterior chamber intraocular lens implantation) under monitored anesthesia care (MAC) with propofol.\n\nParticipants are randomly assigned to either a binaural beat group or a control group. The binaural beat group will wear earphones and listen to binaural beats from the time they arrive at the operating room until the surgery is completed. The control group will wear identical earphones but will not receive any auditory stimulus.\n\nDuring the procedure, standard vital signs and the bispectral index (BIS) will be continuously monitored in both groups. Following the surgery, the investigators will assess the patients' overall satisfaction using a 7-point Likert scale. Secondary assessments include patient preference for the anesthesia method, intraoperative pain intensity, sedation level, anxiety level, and quality of life (EQ-VAS) measured by a visual analogue scale. Any surgery-related discomfort or adverse events will also be recorded and compared between the two groups.",[26,27,28],"Cataract","Binaural Beats","Geriatric Anesthesia","RECRUITING","2026-05-19",{"date":32,"type":33},"2026-05-27","ACTUAL",{"date":35,"type":33},"2025-08-07",{"date":37,"type":20},"2026-07-08",{"name":39,"class":40},"Seoul National University Hospital","OTHER",1,{"id":43,"slug":44,"hasResults":11,"nctId":45,"briefTitle":46,"officialTitle":47,"acronym":4,"eligibilityCriteria":48,"healthyVolunteers":11,"sex":16,"minAge":17,"maxAge":4,"enrollmentInfo":49,"targetDuration":51,"studyType":52,"phases":4,"briefSummary":53,"conditions":54,"keywords":4,"overallStatus":56,"whyStopped":4,"lastUpdateSubmitDate":57,"lastUpdatePostDateStruct":58,"startDateStruct":60,"completionDateStruct":62,"leadSponsor":64,"locationsCount":4},"100634825","systemic-immun-inflamation-score-corelation-in-postoperative-patients-prognosis-100634825","NCT07544719","Systemic Immun Inflamation Score Corelation in Postoperative Patients Prognosis","Prognostic Value of Systemic Immun Inflamation Index in Geriatrik Patient Admitted to the ICU After Surgery: A Prospective Observational Study","Inclusion Criteria:\n\n* The patient must be 65 years of age or older (in the geriatric age group),\n* Admitted to the intensive care unit after elective or emergency surgery\n* Have access to complete blood count (hemogram) data (neutrophils, lymphocytes, platelets) during their stay in the intensive care unit\n* Be able to undergo 30-day mortality monitoring from the date of admission to the intensive care unit\n* Have provided informed consent from the patient or their legal representative.\n\nExclusion Criteria:\n\n* Patients under 65 years of age\n* Patients admitted to the intensive care unit for non-surgical reasons (e.g., trauma, medical intensive care indications)\n* Patients with deficient neutrophil, lymphocyte, or platelet counts upon admission to the intensive care unit\n* Patients with a history of malignancy, hematological disease, or immunosuppressive therapy\n* Terminally ill palliative patients\n* Patients who refuse informed consent.",{"count":50,"type":20},150,"30 Days","OBSERVATIONAL","The Systemic Immuno-Inflammation Index (SII) is a ratio derived from complete blood count parameters (neutrophils, lymphocytes, platelets) and is a non-invasive and easily calculable biomarker. The SIPI effectively reflects both local and systemic inflammatory responses in the human body. It has been used to predict and evaluate the prognosis of various solid tumors such as gastric cancer, non-small cell lung cancer, and colorectal cancer. Furthermore, the SIPI has been shown to have significant prognostic value in cardiovascular and cerebrovascular diseases. In this study, the SIPI will be calculated using laboratory data at the time of admission to the intensive care unit, and the relationship between the obtained values and the 30-day mortality status of the patients will be analyzed.",[28,55],"Postop Adult ICU Patients","NOT_YET_RECRUITING","2026-04-18",{"date":59,"type":33},"2026-04-22",{"date":61,"type":20},"2026-06-15",{"date":63,"type":20},"2026-07-30",{"name":65,"class":66},"Malatya Egitim Ve Arastirma Hastanesi","OTHER_GOV",{"id":68,"slug":69,"hasResults":11,"nctId":70,"briefTitle":71,"officialTitle":72,"acronym":4,"eligibilityCriteria":73,"healthyVolunteers":11,"sex":16,"minAge":17,"maxAge":4,"enrollmentInfo":74,"targetDuration":4,"studyType":52,"phases":4,"briefSummary":76,"conditions":77,"keywords":4,"overallStatus":56,"whyStopped":4,"lastUpdateSubmitDate":80,"lastUpdatePostDateStruct":81,"startDateStruct":83,"completionDateStruct":85,"leadSponsor":87,"locationsCount":41},"100624425","risk-prediction-model-for-older-adults-undergoing-noncardiac-surgery-100624425","NCT07409467","Risk Prediction Model for Older Adults Undergoing Noncardiac Surgery","Development of a Surgical Risk Prediction Model for Older Adults Undergoing Major Noncardiac Surgery: A Prospective Cohort Study","Inclusion Criteria:\n\n* Patients aged 65 years or older scheduled for elective surgery who visit the preoperative assessment clinic.\n* Patients scheduled for major non-cardiac surgery.\n* Patients who voluntarily provide written informed consent.\n\nExclusion Criteria:\n\n* Patients unable to communicate.\n* Patients unable to complete questionnaires or perform physical function tests.\n* Patients with implanted electronic medical devices, such as cardiac pacemakers or implantable patient monitoring devices.\n* Patients whose scheduled surgery is cancelled.\n* Patients with underlying medical or psychiatric conditions that may affect the study outcomes.\n* Any other reason that, in the opinion of the investigator, makes the patient unsuitable for participation.",{"count":75,"type":20},520,"This prospective observational study aims to develop and evaluate predictive models for postoperative complications in patients aged 65 years or older scheduled for elective major surgery. The investigators will recruit 520 eligible patients visiting the preoperative assessment clinic.\n\nThe study involves the prospective collection of comprehensive preoperative data using specific validated tools:\n\n* Physical Activity: Assessed using the Saltin-Grimby Physical Activity Scale (SGPAS) to categorize physical activity intensity.\n* Nutritional Risk: Screened using the Nutritional Risk Screening 2002 (NRS-2002) tool.\n* Psychological Status: Evaluated for anxiety and depression using the Hospital Anxiety and Depression Scale (HADS).\n* Body Composition: Measured using a portable bioelectrical impedance analysis (BIA) device (BWA2.0S, InBody) to assess muscle mass, body fat\u002Fwater, and phase angle.\n* Physical Function: Assessed via the short physical performance battery (SPPB) using electronic measurement devices (AndanteFit, DYPHI) to calculate frailty index and physical age.\n\nThe primary endpoint is the occurrence and severity of postoperative complications within 30 days, evaluated using both the Clavien-Dindo Classification and the Comprehensive Complication Index (CCI). Using the collected dataset, the investigators will develop prediction models using both classical regression analysis and machine learning algorithms to compare their predictive performance.",[78,28,79],"Major Noncardiac Surgery","Postoperative Complications","2026-02-08",{"date":82,"type":33},"2026-02-13",{"date":84,"type":20},"2026-02-19",{"date":86,"type":20},"2027-02-28",{"name":39,"class":40},{"id":89,"slug":90,"hasResults":11,"nctId":91,"briefTitle":92,"officialTitle":93,"acronym":4,"eligibilityCriteria":94,"healthyVolunteers":11,"sex":16,"minAge":17,"maxAge":4,"enrollmentInfo":95,"targetDuration":4,"studyType":52,"phases":4,"briefSummary":97,"conditions":98,"keywords":103,"overallStatus":56,"whyStopped":4,"lastUpdateSubmitDate":110,"lastUpdatePostDateStruct":111,"startDateStruct":113,"completionDateStruct":114,"leadSponsor":116,"locationsCount":41},"100619015","the-effect-of-single-lung-ventilation-duration-and-intraoperative-brain-oxygenation-on-cognitive-function-and-postoperative-pain-in-geriatric-patients-100619015","NCT07339124","The Effect of Single Lung Ventilation Duration and Intraoperative Brain Oxygenation on Cognitive Function and Postoperative Pain in Geriatric Patients","The Effect of Single Lung Ventilation Duration and Intraoperative Brain Oxygenation on Cognitive Function and Postoperative Pain in Geriatric Patients Undergoing Single Lung Ventilation; Prospective Observational Study","Inclusion Criteria:\n\n* Patients aged 65 and over with a high school diploma or higher education\n* Patients undergoing lung resection via thoracotomy (wedge resection, lingulectomy, segmentectomy, lobectomy, pneumonectomy)\n* American Society of Anesthesiologists (ASA) score I-II-III,\n* Body mass index (BMI) between 18-40 kg\u002Fm2,\n* Patients undergoing surgery under general anesthesia will be included in the study.\n\nExclusion Criteria:\n\n* Patients under 65 years of age, patients over 65 who are illiterate,\n* Who have completed primary or secondary school,\n* Patients with pre-existing cognitive impairment confirmed by preoperative Mini Mental State Examination (MMSE),\n* Patients with a history of previously diagnosed mental illness, cerebrovascular disease, senile dementia, stroke,\n* Patients using continuous anti-inflammatory\u002Fanalgesic medications,\n* Patients with preoperative chronic pain,\n* Severe cardiovascular disease,\n* Diagnosed neurological and psychiatric diseases,\n* Patients allergic to the anesthetic and analgesic drugs to be administered,\n* Patients with severe renal failure, gastrointestinal ulceration or severe asthma that prevents the administration of standard analgesia protocols,\n* Patients undergoing surgery other than lung resection,\n* Patients undergoing surgery with TIVA (total intravenous anesthesia) will be excluded from the study.",{"count":96,"type":20},30,"One lung ventilation (OLV) is commonly used in thoracic surgery. Although the lack of ventilation of the lung in the surgical area (independent lung) during OLV redirects pulmonary blood flow to the dependent lung, shunt development is inevitable, and consequently, hypoxia is a frequently encountered condition. Therefore, one of the most important aspects that clinicians pay attention to during OLV is cerebral oxygen saturation in addition to peripheral oxygenation monitoring.\n\nStudies have shown a correlation between decreased cerebral oxygen saturation and postoperative cognitive dysfunction (POCD). Patients undergoing OLV are also at risk of cerebral desaturation due to this non-physiological ventilation.\n\nPatients undergoing OLV are at risk of cerebral oxygen desaturation. Therefore, in these patients, both cognitive dysfunction and changes in brain oxygenation can negatively affect pain-related centers, altering pain perception. Geriatric patients are particularly more affected by these negative effects. It is generally accepted by healthcare professionals specializing in pain management that the application of pain management should differ for elderly patients compared to younger patients. Analgesic dose adjustment should be done more carefully in geriatric patients. Increased sensitivity to opioids due to hypoxia can cause respiratory depression and increased analgesic effects. To avoid these, opioid dose adjustment is necessary in these patients. In conclusion, cerebral oxygen saturation measurement can be an effective method to detect cerebral oxygen desaturation, especially in the geriatric patient group. In this way, the effect of hypoxia caused by OLV on cerebral oxygen saturation can be detected early, and POCD can be limited. We believe that this situation can also contribute to effective postoperative pain management. This study aimed to investigate the effect of intraoperative brain oxygenation on cognitive function and postoperative pain in geriatric patients who underwent OLV.\n\nMATERİAL AND METHODS This study will be conducted in accordance with the Helsinki Declaration and will take place at Health Sciences University Ankara Atatürk Sanatorium Training and Research Hospital . The study will be planned for geriatric patients over 65 years of age with a high school diploma or higher education level who have given informed consent and are scheduled for OLV with standard anesthesia monitoring. These patients, undergoing thoracic surgery via thoracotomy and who agree to participate in this study and sign an informed consent form, will be prospectively enrolled. A total of 30 patients will be included in our study. Preoperatively, patients will undergo standard monitoring including non-invasive arterial blood pressure, electrocardiography, and peripheral oxygen saturation (SpO2). Cerebral oxygenation of patients who have signed an informed consent form the day before will be recorded throughout the surgical procedure using probes placed on the forehead before the induction of anesthetic drugs.\n\nThe standard anesthesia and analgesia protocol that we routinely apply to patients will be applied throughout the surgery. Routine preoperative blood tests, age, height, weight, Body Mass Index (BMI), gender, diagnosis, preoperative comorbidities (hypertension, diabetes, coronary artery disease, chronic obstructive pulmonary disease, etc.), previous surgeries (any surgical procedure performed under general anesthesia before this study), American Society of Anesthesiologists ( ASA) score, and duration of surgery will be recorded for each patient. Hemodynamic data (systolic arterial pressure (SAP), diastolic arterial pressure (DAP), mean arterial pressure (MAP), pulse, SpO2, and cerebral oxygen saturation will be recorded before anesthesia induction, after induction, and at 5, 10, 20, 30, and 60 minutes after the start of OLV. These hemodynamic data will also be recorded at the end OLV and at the end of the operation. OLV duration, anesthesia duration, surgery duration, amount of fluid administered, urine output, and whether blood replacement was performed will be recorded. Visual Analog Scale (VAS) scores will be recorded at 1, 2, 4, 8, 16, and 24 hours postoperatively. Analgesic medications administered during the 24-hour postoperative period will also be recorded. VAS evaluation will be performed on a 100 mm scale, where 0: no pain and 100: maximum pain, indicating the patient's pain level. During this process, any possible side effects that may develop due to analgesic treatment will be recorded.\n\nThe Mini Mental Test (MMT) form will be completed by patients one day before surgery, 48 hours postoperatively, on the 7th day postoperatively. MMT consists of eleven items grouped under five main headings: Orientation, recording memory, attention and calculation, recall, and language, and is evaluated out of a total score of 30.",[99,28,100,101,102],"Thoracic Anesthesia","One Lung Ventillation (OLV)","POCD - Postoperative Cognitive Dysfunction","Postoperative Pain Management",[104,105,106,107,108,109],"thoracic anesthesia","geriatric patients","cognitive function","one lung ventilation","cerebral oxygenation","postoperative pain","2026-01-14",{"date":112,"type":33},"2026-01-15",{"date":112,"type":20},{"date":115,"type":20},"2026-10-30",{"name":117,"class":66},"Ankara Ataturk Sanatorium Training and Research Hospital",{"id":119,"slug":120,"hasResults":11,"nctId":121,"briefTitle":122,"officialTitle":123,"acronym":4,"eligibilityCriteria":124,"healthyVolunteers":11,"sex":16,"minAge":17,"maxAge":125,"enrollmentInfo":126,"targetDuration":4,"studyType":52,"phases":4,"briefSummary":128,"conditions":129,"keywords":4,"overallStatus":56,"whyStopped":4,"lastUpdateSubmitDate":132,"lastUpdatePostDateStruct":133,"startDateStruct":135,"completionDateStruct":137,"leadSponsor":139,"locationsCount":4},"100598708","nol-guided-vs-conventional-intraoperative-opioid-infusion-on-outcomes-in-geriatric-patients-100598708","NCT07075003","NOL-Guided vs Conventional Intraoperative Opioid Infusion on Outcomes in Geriatric Patients","Effect of NOL-Guided vs Conventional Intraoperative Opioid Infusion on Outcomes in Geriatric Patients Undergoing Lumbar Stabilization Surgery","Inclusion Criteria:\n\n* Patients undergoing lumbar stabilization surgery\n\nExclusion Criteria:\n\n* Chronic opioid use\n* Severe congestive heart failıure\n* Severe arrhythmia\n* Uncontrolled hypertension","90 Years",{"count":127,"type":20},80,"The aim of this study is to compare the effects of conventional methods and goal-directed therapy guided by pain monitoring on total remifentanil dosage, wake-up time, and complications in geriatric patients undergoing lumbar stabilization surgery.",[130,131,28],"Pain","Opioid Use","2025-07-10",{"date":134,"type":33},"2025-07-20",{"date":136,"type":20},"2025-07",{"date":138,"type":20},"2025-10",{"name":140,"class":40},"Saglik Bilimleri Universitesi"]