[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"gingival-recession-generalized-moderate\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:gingival-recession-generalized-moderate":26},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,2,0,[8,55],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":4,"eligibilityCriteria":15,"healthyVolunteers":11,"sex":16,"minAge":17,"maxAge":4,"enrollmentInfo":18,"targetDuration":4,"studyType":21,"phases":22,"briefSummary":24,"conditions":25,"keywords":33,"overallStatus":42,"whyStopped":4,"lastUpdateSubmitDate":43,"lastUpdatePostDateStruct":44,"startDateStruct":47,"completionDateStruct":49,"leadSponsor":51,"locationsCount":54},"100605131","comparing-caf-and-tcaf-with-soft-tissue-grafting-for-treating-multiple-recessions-in-the-maxilla-100605131",false,"NCT07158528","Comparing CAF and TCAF With Soft Tissue Grafting for Treating Multiple Recessions in the Maxilla.","An RCT Comparing Coronally Advanced Flap (CAF) and Tunneled Coronally Advanced Flap (TCAF) in Combination With a Soft Tissue Graft for Multiple Recessions Coverage in the Maxilla.","Inclusion Criteria:\n\n* At least 18 years of age\n* Good oral hygiene\n* Presence of multiple gingival recessions in the maxilla\n* Good general health\n\nExclusion Criteria:\n\n* Smoker\n* Pregnant women (assessed at each visit; if the patient becomes pregnant during follow-up, radiographs will not be taken)","ALL","18 Years",{"count":19,"type":20},34,"ESTIMATED","INTERVENTIONAL",[23],"NA","Multiple techniques can be used for recession coverage. The most common techniques are: tunnel technique (T), coronally advanced flap (CAF) or a combination of both (TCAF). Tunnel and coronally advanced flap are frequently used in clinical practice, whereas the combined technique is a relatively recently developed surgical approach.\n\nThis randomized controlled trial compares CAF and TCAF to determine which technique provides better root coverage for receding gums at multiple adjacent teeth in the upper jaw. The main question it aims to answer is:\n\n\\- What is the average root coverage achieved with each technique in the short and long term? This may be clinically relevant because covering gum recession can reduce tooth sensitivity, improve aesthetics and make oral hygiene easier.\n\nResearchers will compare the coronally advanced flap (CAF = the gum is detached and repositioned higher) with the tunneled coronally advanced flap (TCAF = the gum is undermined, only partially detached and repositioned higher). In both techniques, a small piece of tissue is removed from the palate, which is used to cover the recession. The purpose of the connective tissue graft under the flap\u002Ftunnel is to increase thickness and provide support.\n\nParticipants will:\n\n* Undergo surgery (CAF or TCAF, randomly assigned) to cover recessions\n* Attend regular check-ups for up to 10 years after surgery\n* Keep a postoperative journal (recording medication use, pain levels, tooth sensitivity, etc.)",[26,27,28,29,30,31,32],"Gingival Recession Generalized Moderate","Gingival Recession Localized Moderate","Gingival Recession, Generalized","Gingival Recession, Localized","Gingival Recession, Plastic Surgery","Gingival Recessions","Gingival Recession, Mucogingival Surgery",[34,35,36,37,38,39,40,41],"TCAF","CAF","tunneled coronally advanced flap","coronally advanced flap","maxilla","multiple recessions","MAGR","multiple adjacent gingival recessions","RECRUITING","2025-09-09",{"date":45,"type":46},"2025-09-16","ACTUAL",{"date":48,"type":46},"2025-08-18",{"date":50,"type":20},"2037-12-31",{"name":52,"class":53},"University Hospital, Ghent","OTHER",1,{"id":56,"slug":57,"hasResults":11,"nctId":58,"briefTitle":59,"officialTitle":60,"acronym":4,"eligibilityCriteria":61,"healthyVolunteers":62,"sex":16,"minAge":17,"maxAge":63,"enrollmentInfo":64,"targetDuration":4,"studyType":21,"phases":66,"briefSummary":67,"conditions":68,"keywords":69,"overallStatus":42,"whyStopped":4,"lastUpdateSubmitDate":73,"lastUpdatePostDateStruct":74,"startDateStruct":76,"completionDateStruct":78,"leadSponsor":80,"locationsCount":54},"100490303","the-use-of-coronary-displaced-flap-and-deepithelialized-free-graft-in-the-treatment-of-multiple-gingival-recessions-100490303","NCT05664373","The Use of Coronary Displaced Flap and Deepithelialized Free Graft in the Treatment of Multiple Gingival Recessions","The Use of Coronary Displaced Flap and Deepithelialized Free Graft in the Treatment of Multiple Adjacent Gingival Recessions - A Randomized Controlled Clinical Study","Inclusion Criteria:\n\n* Age between 18 and 60 years,\n* Non-smokers or consumption of up to 10 cigarettes per day,\n* no signs of gingival inflammation,\n* Presence of at least two single-rooted teeth with type I gingival recession ≥2 mm deep on the buccal side on both sides of the jaw,\n* Plaque index (PI) and gingival bleeding on provocation (BOP) \\\u003C15% and probing depth (PPD) \\\u003C3 mm,\n* Absence of non-carious cervical lesions (NCL) and undetectable cemento-enamel junctionr (CEJ) at defect sites,\n* No history of previous periodontal plastic surgery on the affected teeth.\n\nExclusion Criteria:\n\n* Presence of carious lesions or restorations in the CEJ area,\n* Use of medications that affect periodontal health and healing,\n* Medical contraindications for periodontal surgical procedures,\n* Pregnancy and breastfeeding.",true,"60 Years",{"count":65,"type":20},50,[23],"Successful treatment of multiple gingival recessions (MRG) is a major challenge in periodontal plastic surgery due to complicated predisposing anatomical features of the surrounding tissues, such as a thin gingival phenotype or a limited zone of keratinized gingiva, variations in the depth and width of adjacent gingival recessions, shallow vestibulum and coronally inserted frenums and\u002For plica.The application of coronary advanced flap (CAF) or tunnel technique (TUN) with connective tissue graft (CTG) gives the best results in the therapy of MRG The application of connective tissue grafts in combination with various surgical techniques is accepted as the \"gold standard\" in GR therapy. A limitation in the application of CTG is the limited region of the donor site, especially in cases where a larger dimension of the CTG is required, or if the thickness of the hard palate tissue is inadequate. Techniques for obtaining subepithelial CTG (S-CTG), whether it is the trap-door technique or the single incision technique, are often associated with postoperative pain and discomfort, as well as necrosis\u002Fdehiscence of the palatal flap at the donor site.\n\nIn order to overcome these limitations and obtain a firmer and more uniform CTG, especially when the thickness of the palatal tissue is inadequate (≤2.5 mm) and when a large dimension of the graft in the apico-coronary or mesio-distal direction is required, deepithelialization of the free gingival graft has been proposed (D-FGG). D-FGG has also been shown to be less prone to postoperative contraction, as it consists predominantly of collagen-rich connective tissue from the lamina propria, while adipose\u002Fglandular tissue is minimally represented. FGG can be deepithelialized intraorally with a diamond bur or diode laser, or extraorally with a scalpel. Despite all the biological advantages of D-FGG, there is scarce evidence in the literature about its histological characteristics after intraoral and extraoral deepithelialization, as well as the clinical outcomes of grafts thus obtained in combination with CAF in the treatment of MGR. Therefore, this aims of the study are to investigate the clinical efficacy and postoperative patient morbidity using D-FGG and modified CAF in the treatment of MGR, as well as to evaluate the histological characteristics of grafts obtained using two different deepithelialization techniques.",[26],[70,71,37,72],"gingival recession","deepithelialized free gingival graft","epithelial remnants","2022-12-17",{"date":75,"type":46},"2022-12-23",{"date":77,"type":46},"2022-11-01",{"date":79,"type":20},"2034-12-10",{"name":81,"class":53},"University of Belgrade"]